Lifepharm

  1. Published

    Plasma and serum serotonin concentrations and surface-bound platelet serotonin expression in Cavalier King Charles Spaniels with myxomatous mitral valve disease

    Cremer, Signe Emilie, Kristensen, Annemarie T., Reimann, Maria Josefine, Eriksen, N. B., Petersen, S. F., Marschner, C. B., Tarnow, I., Oyama, M. A. & Olsen, Lisbeth Høier, 2015, In: American Journal of Veterinary Research. 76, 6, p. 520-531 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Plasma lipid oxidation predicts atherosclerotic status better than cholesterol in diabetic apolipoprotein E deficient mice

    Petersen, Karen Ekkelund, Lykkesfeldt, Jens, Raun, K. & Rakipovski, G., Jan 2017, In: Experimental Biology and Medicine (Maywood). 242, 1, p. 88-91

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Plasma proANP and SDMA and microRNAs are associated with chronic mitral regurgitation in a pig model

    Cirera, Susanna, Moesgaard, S. G., Zois, N. E., Ravn, N., Goetze, Jens P. , Cremer, Signe Emilie, Teerlink, T., Leifsson, Páll S., Honge, J. L., Hasenkam, J. M. & Olsen, Lisbeth Høier, 2013, In: Endocrine Connections. 2, 3, p. 161-171 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease

    Reimann, Maria Josefine, Fredholm, Merete, Cremer, Signe Emilie, Christiansen, L. B., Meurs, K. M., Møller, J. E., Häggström, J., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Journal of Veterinary Internal Medicine. 35, 6, p. 2596-2606

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in Guinea Pigs

    Jensen, Peter Østrup, Lykkesfeldt, Jens, Bjarnsholt, Thomas, Hougen, H. P., Høiby, Niels & Ciofu, Oana, 2012, In: Basic & Clinical Pharmacology & Toxicology. 110, 4, p. 353-358 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Poor vitamin C status late in pregnancy is associated with increased risk of complications in type 1 diabetic women: A cross-sectional study

    Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, 2017, In: Nutrients. 9, 3, 9 p., 186.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Positive charge, negative effect: the impact of cationic nanoparticles in the brain

    Møller, Peter & Lykkesfeldt, Jens, Jul 2014, In: Nanomedicine. 9, 10, p. 1441-3 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  8. Published

    Potassium and calcium channel gene expression in small arteries in porcine and rat models of diet-induced obesity (Poster)

    Jensen, Lars Jørn, Salomonsson, M., Sorensen, Charlotte Mehlin, von Holstein-Rathlou, Niels-Henrik, Pedersen, H. D., Christoffersen, B. Ø., Olsen, Lisbeth Høier & Ludvigsen, Trine Pagh, 27 Apr 2014, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28, Supplement 1, 1 p., 676.4.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  9. Published

    Predictive validity and immune cell involvement in the pathogenesis of piroxicam-accelerated colitis in interleukin-10 knockout mice

    Holgersen, Kristine, Kvist, P. H., Hansen, Axel Kornerup & Holm, T. L., 2014, In: International Immunopharmacology. 21, 1, p. 137-147 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Prenatal vitamin C deficiency results in differential levels of oxidative stress during late gestation in foetal guinea pig brains

    Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Redox Biology. 2, p. 361-367 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    ProANP plasma measurement predicts all-cause mortality in acutely hospitalised patients: a cohort study

    Lauridsen, B. K., Iversen, K., Hunter, I., Bay, M., Kirk, V., Nielsen, O. W., Nielsen, H., Boesgaard, S., Køber, Lars Valeur & Goetze, J. P., 2013, In: B M J Open. 3, 10 p., e003288.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Prolonged effect of a new O-glycoPEGylated FVIII (N8-GP) in a murine saphenous vein bleeding model

    Pastoft, A. E., Ezban, M., Tranholm, M., Lykkesfeldt, Jens & Lauritzen, B., 2013, In: Haemophilia Online. 19, 6, p. 913-919 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Prolonged insulin-induced hypoglycaemia reduces ß-cell activity rather than number in pancreatic islets in non-diabetic rats

    Jensen, Vivi Flou Hjorth, Mølck, A. M., Nowak, J., Fels, J. J., Lykkesfeldt, Jens & Bøgh, I. B., 2022, In: Scientific Reports. 12, 14113.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Prolonged maternal vitamin C deficiency overrides preferential fetal ascorbate transport but does not influence perinatal survival in guinea pigs

    Schjoldager, J. G., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: British Journal of Nutrition. 110, 9, p. 1573-1579 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Pronounced inflammatory response to endotoxaemia during nighttime: a randomised cross-over trial

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, I., 2014, In: PloS one. 9, 1, 7 p., e87413.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Proteoglycan synthesis rate as a novel method to measure blood-induced cartilage degeneration in non-haemophilic and haemophilic rats

    Pulles, A. E., Vøls, Kåre Kryger, Christensen, K. R., Coeleveld, K., Hansen, Axel Kornerup, van Vulpen, L. F. D., Petersen, M., Mastbergen, S. C., Roepstorff, K., Schutgens, R. E. G., Kjelgaard-Hansen, M. & Lafeber, F. P. J. G., 2020, In: Haemophilia. 26, 3, p. e88-e96

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Proximal Neuropathy and Associated Skeletal Muscle Changes Resembling Denervation Atrophy in Hindlimbs of Chronic Hypoglycaemic Rats

    Jensen, Vivi Flou Hjorth, Molck, A. M., Soeborg, H., Nowak, J., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., Jan 2018, In: Basic & Clinical Pharmacology & Toxicology. 122, 1, p. 165-175

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Pulsatile Hyperglycaemia Induces Vascular Oxidative Stress and GLUT 1 Expression More Potently than Sustained Hyperglycaemia in Rats on High Fat Diet

    Rakipovski, G., Lykkesfeldt, Jens & Raun, K., 20 Jan 2016, In: P L o S One. 11, 1, e0147412.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Quality of life assessment in dogs and cats receiving chemotherapy: a review of current methods

    Vøls, Kåre Kryger, Heden, M. A., Kristensen, Annemarie T. & Sandøe, Peter, 2017, In: Veterinary and Comparative Oncology. 15, 3, p. 684–691 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    R-R interval variations influence the degree of mitral regurgitation in dogs with myxomatous mitral valve disease

    Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2013.

    Research output: Contribution to conferencePosterResearch

  21. Published

    R-R interval variations influence the degree of mitral regurgitation in dogs with myxomatous mitral valve disease

    Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: The Veterinary Journal. 199, 3, p. 348-354 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Radial and longitudinal strain and strain rate assessed by speckle-tracking echocardiography in dogs with myxomatous mitral valve disease

    Zois, N. E., Tidholm, A., Nägga, K. M., Moesgaard, S. G., Rasmussen, C. E., Falk, B. T., Häggström, J., Pedersen, H. D., Åblad, B., Nilsen, H. Y. & Olsen, Lisbeth Høier, 2012, In: Journal of Veterinary Internal Medicine. 26, 6, p. 1309-1319 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Randall Selitto pressure algometry for assessment of bone-related pain in rats

    Falk, S., Ipsen, David Højland, Appel, C. K., Ugarak, A., Durup, D., Dickenson, A. H. & Heegaard, Anne-Marie, 2015, In: European Journal of Pain. 19, 3, p. 305-312 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Rapid inflammation and early degeneration of bone and cartilage revealed in a time-course study of induced haemarthrosis in haemophilic rats

    Christensen, K. R., Kjelgaard-Hansen, M., Nielsen, Lise Nikolic, Wiinberg, B., Althoehn, F. A., Poulsen, N. B., Vøls, Kåre Kryger, Thyme, A. P., Lovgren, K. M., Hansen, Axel Kornerup & Roepstorff, K., 2019, In: Rheumatology. 58, 4, p. 588-599

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Reduced Mechanical Stretch Induces Enhanced Endothelin B Receptor-mediated Contractility via Activation of Focal Adhesion Kinase and Extra Cellular-regulated Kinase 1/2 in Cerebral Arteries from Rat

    Spray, S., Rasmussen, M. N. P., Skovsted, Gry Freja, Warfvinge, K., Sheykhzade, Majid & Edvinsson, L., Jun 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 1, p. 68-77 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Reduced early life mucosal integrity decreases thymic cell counts and increases local, but not thymic regulatory, T cell recruitment: Gut mucosal integrity breach and thymic T cells

    Zakariassen, Hannah Louise, Bendtsen, K. M., Tougaard, P. & Hansen, Axel Kornerup, 2019, In: European Journal of Inflammation. 17, p. 1-16

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Regulation of vitamin C homeostasis during deficiency

    Lindblad, M. M., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrients. 5, 8, p. 2860-2879 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Reply to Hemilä by Lykkesfeldt and Poulsen

    Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2011, In: British Journal of Nutrition. 105, 3, p. 488 1 p.

    Research output: Contribution to journalLetterResearchpeer-review

  29. Published

    Rodent model choice has major impact on variability of standard preclinical readouts associated with diabetes and obesity research

    Jensen, Victoria Svop, Porsgaard, T., Lykkesfeldt, Jens & Hvid, H., 15 Aug 2016, In: American Journal of Translational Research. 8, 8, p. 3574-3584

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Role of S1P-receptor and Rho-kinase in myogenic tone in mesenteric and cerebral arteries of young vs. middle-aged mice

    Skovsted, Gry Freja, Aupetit, A., Björling , K., Haanes, K. A., Syberg, S., Jørgensen, N. R., Freude, Kristine, Pearson, J. T. & Jensen, Lars Jørn, 2023, In: Acta Physiologica. 239, S728, e14042.

    Research output: Contribution to journalConference abstract in journalCommunication

  31. Published

    Role of pannexin and adenosine triphosphate (ATP) following myocardial ischemia/reperfusion

    Kristiansen, S. B., Skovsted, Gry Freja, Berchtold, L. A., Radziwon-Balicka, A., Dreisig, K., Edvinsson, L., Sheykhzade, Majid & Haanes, Kristian Agmund, 2018, In: Scandinavian Cardiovascular Journal. 52, 6, p. 340-343

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Role of vitamin C and E supplementation on IL-6 in response to training

    Yfanti, C., Fischer, C. P., Nielsen, S., Åkerström, T., Nielsen, A. R., Veskoukis, A. S., Kouretas, D., Lykkesfeldt, Jens, Pilegaard, Henriette & Pedersen, Bente Klarlund, 2012, In: Journal of Applied Physiology. 112, 6, p. 990-1000 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    SK channel inhibition did not increase short-term variability of the QT intervals in atrial tachypaced pigs with left ventricular dysfunction in contrast to the positive control dofetilide

    Citerni, C., Kirchhoff, J., Olsen, Lisbeth Høier, Gentilini, F., Forni, M., Zannoni, A., Edvardsson, N., Bentzen, B., Grunnet, M. & Diness, J., 2018, In: European Heart Journal. 39, S1, p. 809-809 P3811.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  34. Published

    Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice

    Zakariassen, Hannah Louise, John, L. M., Lykkesfeldt, Jens, Raun, K., Glendorf, T., Schaffer, L., Lundh, S., Secher, A., Lutz, T. A. & Le Foll, C., 2020, In: Neuropharmacology. 167, 107987.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Semaglutide treatment attenuates vessel remodelling in ApoE−/− mice following vascular injury and blood flow perturbation

    Jensen, Ditte Marie, Skovsted, Gry Freja, Bonde, M. F. B., Bentzon, J. F., Rolin, B., Franck, G., Ougaard, M. K. E., Voetmann, Louise Marie, Bachmann, J. C., Uryga, A., Pyke, C., Kirk, R. K., Hvid, H., Knudsen, L. B., Lykkesfeldt, Jens & Nyberg, M., 2022, In: Atherosclerosis Plus. 49, p. 32-41 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Serotonin concentration is elevated in platelet-rich plasma and left ventricular myocardial and mitral valve leaflet tissue in dogs with myxomatous mitral valve disease

    Cremer, Signe Emilie, Singletary, G. E., Olsen, Lisbeth Høier, Wallace, K., Häggström, J., Ljungvall, I., Höglund, K., Reynolds, C. A., Pizzinat, N. & Oyama, M. A., 2014.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  37. Published

    Serotonin concentrations in platelets, plasma, mitral valve leaflet, and left ventricular myocardial tissue in dogs with myxomatous mitral valve disease

    Cremer, Signe Emilie, Singletary, G. E., Olsen, Lisbeth Høier, Wallace, K., Häggström, J., Ljungvall, I., Höglund, K., Reynolds, C. A., Pizzinat, N. & Oyama, M. A., 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1534-1540 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Serotonin markers show altered transcription levels in an experimental pig model of mitral regurgitation

    Cremer, Signe Emilie, Zois, N. E., Moesgaard, S. G., Ravn, N., Cirera, Susanna, Honge, J. L., Smerup, M. H., Hasenkam, J. M., Sloth, E., Leifsson, Páll S., Falk, B. T., Oyama, M. A., Orton, C., Martinussen, Torben & Olsen, Lisbeth Høier, 2015, In: The Veterinary Journal. 203, 2, p. 192-198 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Short communication: Gut microbial colonization of the mouse colon using faecal transfer was equally effective when comparing rectal inoculation and oral inoculation based on 16S rRNA sequencing

    Lützhøft, Ditte Olsen, Sánchez-Alcoholado, L., Tougaard, P., Mentzel, Caroline M. Junker, Kot, Witold, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2019, In: Research in Veterinary Science. 126, p. 227-232 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Similar Adiponectin Levels in Obese Normotensive and Obese Hypertensive Men and No Vasorelaxant Effect of Adiponectin on Human Arteries

    Dreier, R., Asferg, C., Berg, J. O., Andersen, U. B., Flyvbjerg, A., Frystyk, J., Linneberg, Allan René, Jeppesen, J. L., Edvinsson, L. & Skovsted, Gry Freja, Feb 2016, In: Basic & Clinical Pharmacology & Toxicology. 118, 2, p. 128–135 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Simultaneous quantification of monoamine neurotransmitters and their biogenic metabolites intracellularly and extracellularly in primary neuronal cell cultures and in sub-regions of guinea pig brain

    Schou-Pedersen, A. M. V., Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 15 Aug 2016, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1028, p. 222-230 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Simvastatin and oxidative stress in humans: A randomized, double-blinded, placebo-controlled clinical trial

    Rasmussen, S. T., Andersen, Jon Thor Trærup, Nielsen, T. K., Cejvanovic, V., Petersen, K. M., Henriksen, T., Weimann, A., Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2016, In: Redox Biology. 9, p. 32-38

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Spatial Memory Dysfunction Induced by Vitamin C Deficiency Is Associated with Changes in Monoaminergic Neurotransmitters and Aberrant Synapse Formation

    Hansen, S. N., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Antioxidants. 7, 7, p. 11 82.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Spontaneous bleeds in the elbows of F8-/- rats cause development of blood-induced joint disease closely resembling human hemophilic arthropathy

    Thyme, A. P., Vøls, Kåre Kryger, Christensen, K. R., Löfgren, Karin Maria, Wiinberg, B., Kvist, P. H., Kjelgaard-Hansen, M., Roepstorff, K., Nielsen, Lise Nikolic & Tranholm, M., 2016.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  45. Published

    Storage-induced increase in biomarkers of oxidative stress and inflammation in red blood cell components

    Kücükakin, B., Kocak, V., Lykkesfeldt, Jens, Nielsen, H. J., Magnussen, K., Rosenberg, Jacob & Gögenür, I., 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 4, p. 299-303 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Strategies for Using Plagiarism Software in the Screening of Incoming Journal Manuscripts: Recommendations Based on a Recent Literature Survey

    Lykkesfeldt, Jens, Aug 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 2, p. 161-164

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Strong association between activated valvular interstitial cells and histopathological lesions in porcine model of induced mitral regurgitation

    Cremer, Signe Emilie, Zois, N. E., Moesgaard, S. G., Ravn, N., Cirera, Susanna, Honge, J. L., Smerup, M. H., Hasenkam, J. M., Sloth, E., Leifsson, Páll S., Falk, B. T., Oyama, M. A., Orton, C., Martinussen, Torben & Olsen, Lisbeth Høier, 2014, In: International Journal of Cardiology. 174, 2, p. 443-446 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  48. Published

    Structural remodeling in cerebral and mesenteric arteries from obese Göttingen minipigs with or without diabetes

    Ludvigsen, Trine Pagh, Olsen, Lisbeth Høier, Pedersen, H. D., Østergaard Christoffersen, B. & Jensen, Lars Jørn, 13 Sep 2018, p. 467P-468P . 2 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  49. Published

    Subcutaneous Administration of Insulin is Associated With Regional Differences in Injection Depot Variability and Kinetics in The Rat

    Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Lykkesfeldt, Jens, Brockhoff, P. M. B., Seested, T. & Refsgaard, H. H. F., 2020, In: Experimental and Clinical Endocrinology and Diabetes. 128, 5, p. 332-338 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Symmetric Dimethylarginine in Cats with Hypertrophic Cardiomyopathy and Diabetes Mellitus

    Langhorn, Rebecca, Kieler, Ida Nordang, Koch, Jørgen, Christiansen, L. B. & Jessen, Lisbeth Rem, Jan 2018, In: Journal of Veterinary Internal Medicine. 32, 1, p. 57-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    TL1A regulates adipose-resident innate lymphoid immune responses and enables diet-induced obesity in mice

    Tougaard, P., Martinsen, L. O., Lützhøft, Ditte Olsen, Jensen, Henrik Elvang, Flethøj, M., Vandenabeele, P., Pedersen, Anders Elm, Skov, Søren, Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2020, In: International journal of obesity (2005). 44, p. 1062–1074

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Tail vein transection bleeding model in fully anesthetized hemophilia A mice

    Carol Illa, Ariadna, Baumgarten, S., Danielsen, D., Larsen, K., Elm, T., Johansen, P. B., Knudsen, T., Lauritzen, B., Tranholm, M. & Ley, C. D., 2021, In: Journal of Visualized Experiments. 175, 17 p., e62952.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published
  54. Published

    Temporal development of dyslipidemia and nonalcoholic fatty liver disease (Nafld) in syrian hamsters fed a high‐fat, high‐fructose, high‐cholesterol diet

    Jensen, Victoria Svop, Fledelius, C., Wulff, E. M., Lykkesfeldt, Jens & Hvid, H., 2021, In: Nutrients. 13, 2, p. 1-18 18 p., 604.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development

    Rasmussen, K. K., Skat-Rørdam, Josephine, Andersen, P., Warzecha, C. B., Pye, M., Andersen, T. A., Ajbro, K. D., Bendsen, E., Narimatsu, M., Vilhardt, Frederik, Pedersen, Lotte Bang, Wrana, J. L., Anderson, R. H., Møllgård, Kjeld, Christensen, Søren Tvorup & Larsen, Lars Allan, 2018, In: Scientific Reports. 8, 1, 14 p., 9542.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    The F8(-/-) rat as a model of hemophilic arthropathy

    Christensen, K. R., Roepstorff, K., Wiinberg, B., Hansen, Axel Kornerup, Tranholm, M., Nielsen, Lise Nikolic & Kjelgaard-Hansen, M., Jun 2016, In: Journal of Thrombosis and Haemostasis. 14, 6, p. 1216-1225 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

    Callø, Kirstine, Geryk, M., Freude, Kristine, Treat, J. A., Vold, V. A., Frederiksen, Henriette Reventlow S, Broendberg, A. K., Frederiksen, T. C., Jensen, H. K. & Cordeiro, J. M., 2022, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 24, 12, p. 2015–2027

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    The Pharmacokinetics of Vitamin C

    Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 10, 20 p., 2412.

    Research output: Contribution to journalReviewResearchpeer-review

  59. Published

    The Zebra Fish IBD Model Assessed By Novel Probe Based TagMan Assays

    Kania, Per, Buchmann, Kurt & Haarder, S., 29 Jun 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  60. Published

    The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers

    Nielsen, C. F., van Putten, S. M., Lund, I. K., Melander, M. C., Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Reckzeh, K., Christensen, K. R., Ingvarsen, S. Z., Gårdsvoll, Henrik, Jensen, K. E., Hamerlik, P., Engelholm, Lars Henning & Behrendt, Niels, 2017, In: OncoTarget. 8, 27, p. 44605-44624 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    The counterregulatory response to hypoglycaemia in the pig

    Gradel, Anna Katrina Jógvansdóttir, Kildegaard, J., Ludvigsen, T. P., Porsgaard, T., Schou-Pedersen, A. M. V., Fels, J. J., Lykkesfeldt, Jens & Refsgaard, H. H. F., Oct 2020, In: Basic & Clinical Pharmacology & Toxicology. 127, 4, p. 278-286

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    The development of nonalcoholic steatohepatitis is subjected to breeder dependent variation in guinea pigs

    Ipsen, David Højland, Agerskov, R. H., Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Scientific Reports. 11, 2955.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    The dietary regulation of LEAP2 depends on meal composition in mice

    Gradel, Anna Katrina Jógvansdóttir, Holm, Stephanie Kjærulff, Byberg, Sarah, Merkestein, M., Hogendorf, W. F. J., Lund, M. L., Buijink, Jesse A., Damgaard, J., Lykkesfeldt, Jens & Holst, Birgitte, 2023, In: FASEB Journal. 37, 6, 21 p., 22923.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    The effect of acetylsalicylic acid and pentoxifylline in guinea pigs with non-alcoholic steatohepatitis

    Ipsen, David Højland, Skat-Rørdam, Josephine, Svenningsen, M., Andersen, Mia Trein, Latta, M., Buelund, Lene Elisabeth, Lintrup, K., Skaarup, R., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 4, p. 583-593

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice

    Rune, Ida, Ellekilde, M., Hansen, Camilla Hartmann Friis, Nielsen, Dennis Sandris, Rolin, B. C., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2011. 1 p.

    Research output: Contribution to conferencePosterResearch

  66. Published

    The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice

    Rune, Ida, Nielsen, Dennis Sandris, Hansen, Axel Kornerup, Ellekilde, M., Lykkesfeldt, Jens, Hansen, Camilla Hartmann Friis & Rolin, B., Nov 2011. 1 p.

    Research output: Contribution to conferencePosterResearch

  67. Published

    The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice

    Rune, Ida, Hansen, Axel Kornerup, Ellekilde, M., Nielsen, Dennis Sandris & Hansen, C., Nov 2011. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  68. Published

    The effect of melatonin on endothelial dysfunction in patients after acute coronary syndrome: The MEFACS randomized clinical trial

    Zahid, J. A., Isbrand, A., Kleif, J., Schou-Pedersen, A. V., Lykkesfeldt, Jens, Madsen, M. T. & Gögenur, Ismail, 2019, In: Journal of Pineal Research. 67, 3, e12600.

    Research output: Contribution to journalLetterResearchpeer-review

  69. Published

    The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study

    Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    The expression signatures in liver and adipose tissue from obese Göttingen Minipigs reveal a predisposition for healthy fat accumulation

    Cirera, Susanna, Taşöz, E., Juul Jacobsen, M., Schumacher-Petersen, Camilla, Østergaard Christoffersen, B., Kaae Kirk, R., Pagh Ludvigsen, T., Hvid, H., Duelund Pedersen, H., Olsen, Lisbeth Høier & Fredholm, Merete, 2020, In: Nutrition and Diabetes. 10, 1, 12 p., 9.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    The genetic consequences of dog breed formation - Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels: [+ correction]

    Axelsson, E., Ljungvall, I., Bhoumik, P., Conn, L. B., Muren, E., Ohlsson, Å., Olsen, L. H., Engdahl, K., Hagman, R., Hanson, J., Kryvokhyzha, D., Pettersson, M., Grenet, O., Moggs, J., Del Rio-Espinola, A., Epe, C., Taillon, B., Tawari, N., Mane, S., Hawkins, T. & 4 others, Hedhammar, Å., Gruet, P., Häggström, J. & Lindblad-Toh, K., 2021, In: PLOS Genetics. 17, 9, 34 p., e1009726.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice

    Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, Ditte Olsen, Halling, Jens Frey, Hansen, M., Al-Soud, W. A., Hansen, Lars Hestbjerg, Kiilerich, P. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    The influence of the young microbiome on inflammatory diseases - lessons from animal studies

    Bendtsen, K. M. B., Fisker, L., Hansen, Axel Kornerup, Hansen, Camilla Hartmann Friis & Nielsen, Dennis Sandris, 2015, In: Birth Defects Research. Part C: Embryo Today Reviews (Print). 105, 4, p. 278-295 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  74. Published

    The intestinal permeability marker FITC-dextran 4kDa should be dosed according to lean body mass in obese mice

    Voetmann, Louise Marie, Rolin, B., Kirk, R. K., Pyke, C. & Hansen, Axel Kornerup, 2023, In: Nutrition and Diabetes. 13, 1.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    The kidneys play a central role in the clearance of rhGH in rats

    Vestergaard, Bill, Thygesen, P., Kreilgaard, M., Fels, J. J., Lykkesfeldt, Jens & Agerso, H., 30 Apr 2016, In: European Journal of Pharmaceutical Sciences. 86, p. 29-33

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    The kidneys play an important role in the clearance of rFVIIa in rats

    Vestergaard, Bill, Appa, R. S., Lykkesfeldt, Jens & Agersø, H., 2014, In: Thrombosis Research. 133, 6, p. 1124-1129 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    The potential of human milk oligosaccharides to impact the microbiota-gut-brain axis through modulation of the gut microbiota

    Al-Khafaji, A. H., Jepsen, Stine Dam, Christensen, K. R. & Vigsnæs, L. K., 2020, In: Journal of Functional Foods. 74, 104176.

    Research output: Contribution to journalReviewResearchpeer-review

  78. Published

    The role of neutrophils and G-CSF in DNFB-induced contact hypersensitivity in mice

    Christensen, A. D., Skov, Søren & Haase, C., 2014, In: Immunity, Inflammation and Disease. 2, 1, p. 21-34 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    The role of vitamin C in epigenetic cancer therapy

    Mikkelsen, Stine Ulrik, Gillberg, Linn, Lykkesfeldt, Jens & Grønbæk, Kirsten, 2021, In: Free Radical Biology and Medicine. 170, p. 179-193 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Thick methacrylate sections devoid of lost caps simplify stereological quantifications based on the optical fractionator design

    Andersen, S. H., Lykkesfeldt, Jens & Larsen, J. O., 15 Sep 2015, In: Anatomical Record. 298, 12, p. 2141-2150 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Third-stage nematode larvae of Contracaecum osculatum from Baltic cod (Gadus morhua) elicit eosinophilic granulomatous reactions when penetrating the stomach mucosa of pigs

    Strøm, S. B., Haarder, S., Korbut, R., Mejer, H., Thamsborg, Stig Milan, Kania, Per & Buchmann, Kurt, 2015, In: Parasitology Research. 114, 3, p. 1217-1220 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Towards a Göttingen minipig model of adult onset growth hormone deficiency: evaluation of stereotactic electrocoagulation method

    Ørstrup, Laura Kofoed Hvidsten, Tvilling, L., Orlowski, D., Zaer, H., Bjarkam, C. R., von Voss, P., Andersen, P. S., Christoffersen, B., Hedemann Sørensen, J. C., Laursen, T., Thygesen, P., Lykkesfeldt, Jens & Glud, A. N., 2019, In: Heliyon. 5, 11, 8 p., e02892.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Toxicological Effects during and following Persistent Insulin-Induced Hypoglycaemia in Healthy Euglycaemic Rats

    Jensen, Vivi Flou Hjorth, Molck, A., Berthelsen, L. O., Alifrangis, L., Andersen, L., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., Jul 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 1, p. 53-66

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Transfer of gut microbiota from lean and obese mice to antibiotic-treated mice

    Ellekilde, M., Selfjord, E. M., Larsen, C. S., Jakesevic, M., Rune, Ida, Christensen, B. T., Vogensen, Finn Kvist, Nielsen, Dennis Sandris, Bahl, M. I., Licht, T. R., Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2014, In: Scientific Reports. 4, 8 p., 5922.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Translational aspects of rectal evoked potentials: a comparative study in rats and humans

    Nissen, T. D., Brock, C., Graversen, C., J. Coen, S., Hultin, L., Aziz, Q., Lykkesfeldt, Jens & Drewes, A. M., 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, p. G119-G128 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Treatment with anti-C5aR mAb leads to early-onset clinical and mechanistic effects in the murine delayed-type hypersensitivity arthritis model

    Atkinson, S. M., Nansen, A., Usher, P. A., Sondergaard, B., Mackay, C. R., Friedrichsen, B., Chang, C., Tang, R., Skov, Søren, Haase, C. & Hornum, L., Nov 2015, In: Autoimmunity. 48, 7, p. 460-470 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Urine 5-hydroxyindoleacetic acid in Cavalier King Charles spaniels with preclinical myxomatous mitral valve disease

    Christiansen, L. B., Cremer, Signe Emilie, Helander, A., Madsen, T., Reimann, Maria Josefine, Møller, J. E., Höglund, K., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2019, In: Veterinary Journal. 250, p. 36-43 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Validation of Piroxicam-Accelerated Colitis in the Interleukin-10 Knock out Mouse - a Preclinical Model Mimicking Human Inflammatory Bowel Disease

    Holgersen, Kristine, Kvist, P. H., Hansen, Axel Kornerup & Holm, T. L., May 2014.

    Research output: Contribution to conferencePosterResearchpeer-review

  89. E-pub ahead of print

    Validation of computed tomography as a diagnostic tool in guinea pigs with non-alcoholic fatty liver disease

    Lintrup, K., Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens, Tveden-Nyborg, Pernille & Buelund, Lene Elisabeth, 2024, (E-pub ahead of print) In: Laboratory Animals.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Variation in diagnostic NAFLD/NASH read-outs in paired liver samples from rodent models

    Jensen, Victoria Svop, Tveden-Nyborg, Pernille, Zacho-Rasmussen, C., Quaade, Michelle Lauge, Ipsen, David Højland, Hvid, H., Fledelius, C., Wulff, E. M. & Lykkesfeldt, Jens, 2020, In: Journal of Pharmacological and Toxicological Methods. 101, 9 p., 106651.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Vascular gene expression in diet-induced atherosclerotic Gottingen minipigs

    Christensen, Liv von Voss, Skovgaard, K., Ludvigsen, T. P., Kirk, R. K., Christoffersen, B. O., Pedersen, H. D., Heegaard, P. M. & Olsen, Lisbeth Høier, Jul 2015, In: Atherosclerosis. 241, 1, p. E85-E85 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  92. Published

    Vasomotor dysfunction in human subcutaneous arteries exposed ex vivo to food-grade titanium dioxide

    Jensen, Ditte Marie, Skovsted, Gry Freja, Lykkesfeldt, Jens, Dreier, R., Berg, J. O., Jeppesen, J. L., Sheykhzade, Majid, Loft, Steffen & Møller, Peter, 2018, In: Food and Chemical Toxicology. 120, p. 321-327 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Vasomotor function in rat arteries after ex vivo and intragastric exposure to food-grade titanium dioxide and vegetable carbon particles

    Jensen, Ditte Marie, Christophersen, D. V., Sheykhzade, Majid, Skovsted, Gry Freja, Lykkesfeldt, Jens, Münter, R., Roursgaard, Martin, Loft, Steffen & Møller, Peter, 26 Feb 2018, In: Particle and Fibre Toxicology. 15, p. 1-18 12.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Visualization of haemophilic arthropathy in F8(-/-) rats by ultrasonography and micro-computed tomography

    Christensen, K. R., Roepstorff, K., Petersen, M., Wiinberg, B., Hansen, Axel Kornerup, Kjelgaard-Hansen, M. & Nielsen, L. N., Jan 2017, In: Haemophilia. 23, 1, 11 p., 152-162.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Vitamin C: From Bench to Bedside

    Carr, A. C. & Lykkesfeldt, Jens, 2021, In: Nutrients. 13, 4, 3 p., 1102.

    Research output: Contribution to journalEditorialResearchpeer-review

  96. Published

    Vitamin C

    Lykkesfeldt, Jens & Carr, A. C., Jan 2024, In: Advances in Nutrition. 15, 1, 100155.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Vitamin C

    Lykkesfeldt, Jens & Carr, A. C., Jan 2024, In: Advances in nutrition (Bethesda, Md.). 15, 1, p. 100155

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Vitamin C

    Lykkesfeldt, Jens, Michels, A. J. & Frei, B., 2014, In: Advances in Nutrition. 5, 1, p. 16-18 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Vitamin C - ascorbic acid

    Frikke-Schmidt, H., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens, Drake, V. J. & Frei, B., 28 Feb 2011, Vitamins in the Prevention of Human Diseases. Walter de Gruyter GmbH and Co. KG, p. 323-362 40 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  100. Published

    Vitamin C Deficiency Exacerbates Dysfunction of Atherosclerotic Coronary Arteries in Guinea Pigs Fed a High-Fat Diet

    Skovsted, Gry Freja, Skat-Rørdam, Josephine, Frøkiær, A. P., Jensen, Henrik Elvang, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2022, In: Antioxidants. 11, 11, 2226.

    Research output: Contribution to journalJournal articleResearchpeer-review