- 2018
- Published
Long-term diet-induced hypertension in rats is associated with reduced expression and function of small artery SKCa, IKCa, and Kir2.1 channels
Gradel, Anna Katrina Jógvansdóttir, Salomonsson, M., Sorensen, Charlotte Mehlin, von Holstein-Rathlou, Niels-Henrik & Jensen, Lars Jørn, 28 Feb 2018, In: Clinical Science. 132, 4, p. 461–474 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vasomotor function in rat arteries after ex vivo and intragastric exposure to food-grade titanium dioxide and vegetable carbon particles
Jensen, Ditte Marie, Christophersen, D. V., Sheykhzade, Majid, Skovsted, Gry Freja, Lykkesfeldt, Jens, Münter, R., Roursgaard, Martin, Loft, Steffen & Møller, Peter, 26 Feb 2018, In: Particle and Fibre Toxicology. 15, p. 1-18 12.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of Three Sample Preparation Procedures for the Quantification of L-Arginine, Asymmetric Dimethylarginine, and Symmetric Dimethylarginine in Human Plasma Using HPLC-FLD
Schou-Pedersen, A. M. V. & Lykkesfeldt, Jens, 1 Feb 2018, In: Journal of Analytical Methods in Chemistry. 2018, 7 p., 6148515.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proximal Neuropathy and Associated Skeletal Muscle Changes Resembling Denervation Atrophy in Hindlimbs of Chronic Hypoglycaemic Rats
Jensen, Vivi Flou Hjorth, Molck, A. M., Soeborg, H., Nowak, J., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., Jan 2018, In: Basic & Clinical Pharmacology & Toxicology. 122, 1, p. 165-175Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Symmetric Dimethylarginine in Cats with Hypertrophic Cardiomyopathy and Diabetes Mellitus
Langhorn, Rebecca, Kieler, Ida Nordang, Koch, Jørgen, Christiansen, L. B. & Jessen, Lisbeth Rem, Jan 2018, In: Journal of Veterinary Internal Medicine. 32, 1, p. 57-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A cafeteria diet alters the decision making strategy and metabolic markers in Sprague-Dawley male rats
Virtuoso, Alessandro, Forkman, Björn, Sarruf, D. A., Tveden-Nyborg, Pernille & Sørensen, Dorte Bratbo, 2018, In: Applied Animal Behaviour Science. 199, p. 35-44 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Abrogating fibrinolysis does not improve bleeding or rFVIIa/rFVIII treatment in a non-mucosal venous injury model in haemophilic rodents
Stagaard, R., Flick, M. J., Bojko, B., Goryński, K., Goryńska, P. Z., Ley, C. D., Olsen, Lisbeth Høier & Knudsen, T., 2018, In: Journal of Thrombosis and Haemostasis. 16, 7, p. 1369-1382 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Absence of functional compensation between coagulation factor VIII and plasminogen in double-knockout mice
Stagaard, R., Ley, C. D., Almholt, K., Olsen, Lisbeth Høier, Knudsen, T. & Flick, M. J., 2018, In: Blood advances. 2, 22, p. 3126-3136 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Early Life Mucosal Insult Temporarily Decreases Acute Oxazolone-Induced Inflammation in Mice
Bendtsen, K. M., Tougaard, P. & Hansen, Axel Kornerup, 2018, In: Inflammation. 41, 4, p. 1437-1447 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Angiotensin-converting enzyme activity in Cavalier King Charles Spaniels with an ACE gene polymorphism and myxomatous mitral valve disease
Meurs, K. M., Olsen, Lisbeth Høier, Reimann, Maria Josefine, Keene, B. W., Atkins, C. E., Adin, D., Aona, B., Condit, J., Defrancesco, T., Reina-Doreste, Y., Stern, J. A., Tou, S., Ward, J. & Woodruff, K., 2018, In: Pharmacogenetics and Genomics. 28, 2, p. 37-40 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies
Tveden-Nyborg, Pernille, Bergmann, T. K. & Lykkesfeldt, Jens, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 233-235 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Biochemical and cognitive effects of docosahexaenoic acid differ in a developmental and SorLA dependent manner
Højland, A., Richner, M., Mølgaard, S., Dieu, R. S., Eskelund, A., Nykjær, A., Nyengaard, J. R., Lykkesfeldt, Jens, Glerup, S. & Nielsen, M. S., 2018, In: Behavioural Brain Research. 348, p. 90-100 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deregulation of obesity-relevant genes is associated with progression in BMI and the amount of adipose tissue in pigs
Mentzel, Caroline M. Junker, Cardoso, T. F., Pipper, C. B., Jacobsen, M. J., Jørgensen, Claus Bøttcher, Cirera, Susanna & Fredholm, Merete, 2018, In: Molecular Genetics and Genomics. 293, 1, p. 129–136 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary fat stimulates development of NAFLD more potently than dietary fructose in Sprague-Dawley rats
Jensen, Victoria Svop, Hvid, H., Damgaard, J., Nygaard, H., Ingvorsen, C., Wulff, E. M., Lykkesfeldt, Jens & Fledelius, C., 2018, In: Diabetology and Metabolic Syndrome. 10, 13 p., 4.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary normalization from a fat, fructose and cholesterol-rich diet to chow limits the amount of myocardial collagen in a Göttingen Minipig model of obesity
Andreasen, L. J., Krog, S., Ludvigsen, T. P., Nielsen, O. L., Møller, J. E., Christoffersen, B. Ø., Pedersen, H. D. & Olsen, Lisbeth Høier, 2018, In: Nutrition and Metabolism. 15, 64.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does colour matter? Preference of mice for different colours of the house mouse igloo: An observational study
Gjendal, K., Ottesen, J. L. & Sørensen, Dorte Bratbo, 2018, In: Scandinavian Journal of Laboratory Animal Science. 44, 6.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early life vitamin C deficiency does not alter morphology of hippocampal CA1 pyramidal neurons or markers of synaptic plasticity in a Guinea pig model
Hansen, S. N., Jørgensen, J. M. B., Nyengaard, J. R., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Nutrients. 10, 6, 749.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by MKL2, ternary complex factors, and actin dynamics
Krawczyk, K. K., Skovsted, Gry Freja, Perisic, L., Dreier, R., Berg, Jais Oliver, Hedin, U., Rippe, C. & Swärd, K., 2018, In: American Journal of Physiology - Cell Physiology. 315, 6, p. C873-C884Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Eye, body or tail? Thermography as a measure of stress in mice
Gjendal, K., Franco, N. H., Ottesen, J. L., Sørensen, Dorte Bratbo & Olsson, I. A. S., 2018, In: Physiology and Behavior. 196, p. 135-143 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability
Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Lykkesfeldt, Jens, Seested, T., Gram-Nielsen, S., Kristensen, N. R. & Refsgaard, H., 2018, In: Journal of Diabetes Research. 2018, 17 p., 1205121.Research output: Contribution to journal › Review › Research › peer-review
- Published
Gut microbiota recovery and immune response in ampicillin-treated mice
Castro Mejia, J. L., Jakesevic, M., Fabricius, N. F., Krych, Lukasz, Nielsen, Dennis Sandris, Kot, W., Bendtsen, K. M. B., Vogensen, Finn Kvist, Hansen, Camilla Hartmann Friis & Hansen, Axel Kornerup, 2018, In: Research in Veterinary Science. 118, p. 357-364 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Have you tried spermine? A rapid and cost-effective method to eliminate dextran sodium sulfate inhibition of PCR and RT-PCR
Krych, Lukasz, Kot, W., Bendtsen, K. M. B., Hansen, Axel Kornerup, Vogensen, Finn Kvist & Nielsen, Dennis Sandris, 2018, In: Journal of Microbiological Methods. 144, p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity
Nasser, A., Møller, A. T., Hellmund, V., Thorborg, S. S., Jespersgaard, C., Bjerrum, Ole Jannik, Dupontd, E., Nachman, G., Lykkesfeldt, Jens, Jensen, T. S. & Møller, L. B., 2018, In: Pain. 159, 6, p. 1012-1024 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-fat feeding induces mobilization of vitamin C in obese prone rats
Tranberg, B., Hellgren, L. I., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2018, In: Research in Veterinary Science. 119, p. 167-169 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Holder C-vitamin dine blodkar sunde?
Skovsted, Gry Freja, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2018Research output: Other contribution › Net publication - Internet publication › Communication
- Published
Liraglutide Decreases Hepatic Inflammation and Injury in Advanced Lean Non-Alcoholic Steatohepatitis
Ipsen, David Højland, Rolin, B., Rakipovski, G., Skovsted, Gry Freja, Madsen, A., Kolstrup, S., Schou-Pedersen, A. M., Skat-Rørdam, Josephine, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 704-713Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long term Westernized diet leads to region-specific changes in brain signaling mechanisms
Hansen, S. N., Ipsen, David Højland, Schou-Pedersen, A. M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Neuroscience Letters. 676, p. 85-91 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics
Rune, Ida, Rolin, B., Lykkesfeldt, Jens, Nielsen, Dennis Sandris, Krych, Lukasz, Kanter, J. E., Bornfeldt, K. E., Kihl, Pernille, Buschard, K., Josefsen, K., Fels, J. J., Mortensen, A., Christoffersen, B., Kirk, R. K. & Hansen, Axel Kornerup, 2018, In: Scientific Reports. 8, 1, 12 p., 5416.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease
Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Cellular and Molecular Life Sciences. 75, 18, p. 3313-3327 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Oral insulin does not alter gut microbiota composition of NOD mice
Kihl, Pernille, Krych, Lukasz, Buschard, K., Wesley, J. D., Kot, W., Hansen, Axel Kornerup, Nielsen, Dennis Sandris & von Herrath, M. G., 2018, In: Diabetes/Metabolism Research and Reviews. 34, 6, 9 p., e3010.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of pannexin and adenosine triphosphate (ATP) following myocardial ischemia/reperfusion
Kristiansen, S. B., Skovsted, Gry Freja, Berchtold, L. A., Radziwon-Balicka, A., Dreisig, K., Edvinsson, L., Sheykhzade, Majid & Haanes, Kristian Agmund, 2018, In: Scandinavian Cardiovascular Journal. 52, 6, p. 340-343Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SK channel inhibition did not increase short-term variability of the QT intervals in atrial tachypaced pigs with left ventricular dysfunction in contrast to the positive control dofetilide
Citerni, C., Kirchhoff, J., Olsen, Lisbeth Høier, Gentilini, F., Forni, M., Zannoni, A., Edvardsson, N., Bentzen, B., Grunnet, M. & Diness, J., 2018, In: European Heart Journal. 39, S1, p. 809-809 P3811.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Spatial Memory Dysfunction Induced by Vitamin C Deficiency Is Associated with Changes in Monoaminergic Neurotransmitters and Aberrant Synapse Formation
Hansen, S. N., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Antioxidants. 7, 7, p. 11 82.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development
Rasmussen, K. K., Skat-Rørdam, Josephine, Andersen, P., Warzecha, C. B., Pye, M., Andersen, T. A., Ajbro, K. D., Bendsen, E., Narimatsu, M., Vilhardt, Frederik, Pedersen, Lotte Bang, Wrana, J. L., Anderson, R. H., Møllgård, Kjeld, Christensen, Søren Tvorup & Larsen, Lars Allan, 2018, In: Scientific Reports. 8, 1, 14 p., 9542.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice
Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, Ditte Olsen, Halling, Jens Frey, Hansen, M., Al-Soud, W. A., Hansen, Lars Hestbjerg, Kiilerich, P. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vasomotor dysfunction in human subcutaneous arteries exposed ex vivo to food-grade titanium dioxide
Jensen, Ditte Marie, Skovsted, Gry Freja, Lykkesfeldt, Jens, Dreier, R., Berg, J. O., Jeppesen, J. L., Sheykhzade, Majid, Loft, Steffen & Møller, Peter, 2018, In: Food and Chemical Toxicology. 120, p. 321-327 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Acute Haemarthrosis in the Haemophilia A Rat Generates a Local and Systemic Proinflammatory Response
Lovgren, K. M., Christensen, K. R., Majewski, W., Ostrup, O., Skov, Søren & Wiinberg, B., Nov 2017, In: Thrombosis and Haemostasis. 117, 11, p. 2092-2104Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hang on: An evaluation of the hemp rope as environmental enrichment in C57BL/6 mice
Gjendal, K., Sørensen, Dorte Bratbo, Kiersgaard, M. K. & Ottesen, J. L., Nov 2017, In: Animal Welfare. 26, 4, p. 437-447 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans: randomised, controlled trials
Larsen, E. L., Cejvanovic, V., Kjær, L. K., Pedersen, M. T., Popik, S. D., Hansen, L. K., Andersen, Jon Thor Trærup, Solem, Espen Victor Jimenez, Broedbaek, K., Petersen, M., Weimann, A., Henriksen, T., Lykkesfeldt, Jens, Torp-Pedersen, C. & Poulsen, Henrik Enghusen, Aug 2017, In: British Journal of Clinical Pharmacology. 83, 8, p. 1643-1653Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Toxicological Effects during and following Persistent Insulin-Induced Hypoglycaemia in Healthy Euglycaemic Rats
Jensen, Vivi Flou Hjorth, Molck, A., Berthelsen, L. O., Alifrangis, L., Andersen, L., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., Jul 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 1, p. 53-66Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pasteurization Procedures for Donor Human Milk Affect Body Growth, Intestinal Structure, and Resistance against Bacterial Infections in Preterm Pigs
Li, Y., Nguyen, Duc Ninh, de Waard, M., Christensen, Lars, Zhou, P., Jiang, Pingping, Sun, Jing, Bojesen, Anders Miki, Lauridsen, C., Lykkesfeldt, Jens, Dalsgaard, T. K., Bering, S. B. & Sangild, Per Torp, Jun 2017, In: Journal of Nutrition. 147, 6, p. 1121-1130Research output: Contribution to journal › Journal article › Research › peer-review
- Published
35Sulphate incorporation assay as a new tool for measuring early cartilage degradation following blood exposure in vitro and in vivo in f8 ko rats
Pulles, A. E., Christensen, K. R., Coeleveld, K., Kjelgaard-Hansen, M., Schutgens, R. E., Lafeber, F. P., Roepstorff, K. & Mastbergen, S. C., Apr 2017, In: Osteoarthritis and Cartilage. 25, S1, p. S156-S157Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ETB receptors via the protein kinase MEK-ERK1/2 signaling pathway in rat
Skovsted, Gry Freja, Kruse, L. S., Berchtold, L. A., Grell, A., Warfvinge, K. & Edvinsson, L., 1 Mar 2017, In: PLOS ONE. 12, 3, 18 p., e0174119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endothelial dysfunction in the early postoperative period after major colon cancer surgery.
Ekeløf, S., Larsen, M. H., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, Feb 2017, In: British Journal of Anaesthesia. 118, 2, p. 200-206Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma lipid oxidation predicts atherosclerotic status better than cholesterol in diabetic apolipoprotein E deficient mice
Petersen, Karen Ekkelund, Lykkesfeldt, Jens, Raun, K. & Rakipovski, G., Jan 2017, In: Experimental Biology and Medicine (Maywood). 242, 1, p. 88-91Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visualization of haemophilic arthropathy in F8(-/-) rats by ultrasonography and micro-computed tomography
Christensen, K. R., Roepstorff, K., Petersen, M., Wiinberg, B., Hansen, Axel Kornerup, Kjelgaard-Hansen, M. & Nielsen, L. N., Jan 2017, In: Haemophilia. 23, 1, 11 p., 152-162.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A porcine subcutaneous Staphylococcus aureus abscess model - a pilot study
Nielsen, O. L., Larsen, M. N., Frees, Dorte, Pedersen, M. M., Skov, Søren & Olsen, Lisbeth Høier, 2017.Research output: Contribution to conference › Conference abstract for conference › Communication
- Published
Assessment of implantable infusion pumps for continuous infusion of human insulin in rats: potential for group housing
Jensen, Vivi Flou Hjorth, Molck, A., Martensson, M., Strid, M. A., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: Laboratory Animals. 51, 3, p. 273-283Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic Hyperinsulinaemic Hypoglycaemia in Rats Is Accompanied by Increased Body Weight, Hyperleptinaemia, and Decreased Neuronal Glucose Transporter Levels in the Brain
Jensen, Vivi Flou Hjorth, Molck, A., Chapman, M., Alifrangis, L., Andersen, L., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: International Journal of Endocrinology. 2017, 14 p., 7861236.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of ES products from Anisakis (Nematoda: Anisakidae) on experimentally induced colitis in adult zebrafish
Haarder, S., Kania, Per, Holm, T., Jørgensen, Louise von Gersdorff & Buchmann, Kurt, 2017, In: Parasite Immunology. 39, 10, 8 p., e12456.Research output: Contribution to journal › Journal article › Research › peer-review
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Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
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Increased systemic oxidatively generated DNA and RNA damage in schizophrenia
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Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
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