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  1. Published

    Diet-Dependent Changes of the DNA Methylome Using a Göttingen Minipig Model for Obesity

    Feng, Y., Cirera, Susanna, Taşöz, E., Liu, Y., Olsen, Lisbeth Høier, Christoffersen, B. Ø., Pedersen, H. D., Ludvigsen, T. P., Kirk, R. K., Schumacher-Petersen, Camilla, Deng, Y., Fredholm, Merete & Gao, Fei, 2021, In: Frontiers in Genetics. 12, 632859.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Diet-induced dyslipidemia leads to nonalcoholic fatty liver disease and oxidative stress in guinea pigs

    Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland, Thiessen, T. S., Feldmann, L. D. B., Lindblad, M. M., Jensen, Henrik Elvang & Lykkesfeldt, Jens, 1 Feb 2016, In: Translational Research. 168, p. 146-160 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Dietary Intervention Accelerates NASH Resolution Depending on Inflammatory Status with Minor Additive Effects on Hepatic Injury by Vitamin E Supplementation

    Klaebel, J. H., Rakipovski, G., Andersen, B., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2020, In: Antioxidants. 9, 9, 808.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Dietary LPS traces influences disease expression of the diet-induced obese mouse

    Lindenberg, F. C. B., Ellekilde, M., Thörn, A. C., Kihl, Pernille, Larsen, C. S., Hansen, Camilla Hartmann Friis, Metzdorff, S. B., Aalbæk, Bent & Hansen, Axel Kornerup, 2019, In: Research in Veterinary Science. 123, p. 195-203 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Dietary Long-Chain Fatty Acids Accelerate Metabolic Dysfunction in Guinea Pigs with Non-Alcoholic Steatohepatitis

    Pedersen, Kamilla, Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2023, In: Nutrients. 15, 2445.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Dietary fat stimulates development of NAFLD more potently than dietary fructose in Sprague-Dawley rats

    Jensen, Victoria Svop, Hvid, H., Damgaard, J., Nygaard, H., Ingvorsen, C., Wulff, E. M., Lykkesfeldt, Jens & Fledelius, C., 2018, In: Diabetology and Metabolic Syndrome. 10, 13 p., 4.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Dietary magnesium deficiency affects gut microbiota and anxiety-like behaviour in C57BL/6N mice

    Jørgensen, B. M. P., Winther, G., Kihl, Pernille, Nielsen, Dennis Sandris, Wegener, G., Hansen, Axel Kornerup & Sørensen, Dorte Bratbo, 2015, In: Acta Neuropsychiatrica (Print). 27, 5, p. 307-311 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Dietary magnesium deficiency alters gut microbiota and leads to depressive-like behaviour

    Winther, G., Jørgensen, B. M. P., Elfving, B., Nielsen, Dennis Sandris, Kihl, Pernille, Lund, S., Sørensen, Dorte Bratbo & Wegener, G., 2015, In: Acta Neuropsychiatrica (Print). 27, 3, p. 168-176 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Dietary normalization from a fat, fructose and cholesterol-rich diet to chow limits the amount of myocardial collagen in a Göttingen Minipig model of obesity

    Andreasen, L. J., Krog, S., Ludvigsen, T. P., Nielsen, O. L., Møller, J. E., Christoffersen, B. Ø., Pedersen, H. D. & Olsen, Lisbeth Høier, 2018, In: Nutrition and Metabolism. 15, 64.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Differential effects of dietary components on glucose intolerance and non‐alcoholic steatohepatitis

    Skat-Rørdam, Josephine, Ipsen, David Højland, Hardam, P. D., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Nutrients. 13, 8, 2523.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Differential toxicological response to positively and negatively charged nanoparticles in the rat brain

    Knudsen, K. B., Northeved, H., Ek, P. K., Permin, A., Andresen, T. L., Larsen, S., Wegener, K. M., Lam, H. R. & Lykkesfeldt, Jens, 2014, In: Nanotoxicology. 8, 7, p. 764-774 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Discordant porcine cardiac natriuretic peptide gene expression and plasma concentrations during the first 72 h of life

    Smith, J., Christoffersen, C., Nørgaard, L. M., Olsen, Lisbeth Høier, Vejlstrup, N. G., Andersen, C. B. & Goetze, J. P., 2012, In: Regulatory Peptides. 177, Supplement, p. S33 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  13. Published

    Discrepancies in global vitamin C recommendations: a review of RDA criteria and underlying health perspectives

    Carr, A. C. & Lykkesfeldt, Jens, 2021, In: Critical Reviews in Food Science and Nutrition. 61, 5, p. 742-755 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Distribution and time course of corticosterone excretion in faeces and urine of female mice with varying systemic concentrations

    Kalliokoski, Otto, Hau, Jann, Jacobsen, K. R., Schumacher-Petersen, Camilla & Abelson, Klas, 2010, In: General and Comparative Endocrinology. 168, 3, p. 450-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Distribution of vitamin C is tissue specific with early saturation of the brain and adrenal glands following differential oral dose regimens in guinea pigs

    Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2015, In: British Journal of Nutrition. 113, 10, p. 1539-1549 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Does Aging Affect Vitamin C Status Relative to Intake? Findings from NHANES 2017-2018

    Carr, A. C. & Lykkesfeldt, Jens, 2023, In: Nutrients. 15, 4, 10 p., 892.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Does Glucagon-like Peptide-1 Ameliorate Oxidative Stress in Diabetes? Evidence Based on Experimental and Clinical Studies

    Petersen, Karen Ekkelund, Rakipovski, G., Raun, K. & Lykkesfeldt, Jens, 2016, In: Current Diabetes Reviews. 12, 4, p. 331-358 28 p.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    Does colour matter? Preference of mice for different colours of the house mouse igloo: An observational study

    Gjendal, K., Ottesen, J. L. & Sørensen, Dorte Bratbo, 2018, In: Scandinavian Journal of Laboratory Animal Science. 44, 6.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Does vitamin C deficiency affect cognitive development and function?

    Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 9, p. 3818-3846 29 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Does vitamin C deficiency increase lifestyle-associated vascular disease progression? evidence based on experimental and clinical studies

    Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Antioxidants & Redox Signaling. 19, 17, p. 2084-2104 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Does vitamin C deficiency promote fatty liver disease development?

    Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 12, p. 5473-5499 27 p.

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies

    Mortensen, A. & Lykkesfeldt, Jens, 2014, In: Nitric Oxide: Biology and Chemistry. 36, p. 51-57 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    Dyslipidemia: Obese or Not Obese-That Is Not the Question

    Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Dec 2016, In: Current Obesity Reports. 5, 4, p. 405-412

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Early life vitamin C deficiency does not alter morphology of hippocampal CA1 pyramidal neurons or markers of synaptic plasticity in a Guinea pig model

    Hansen, S. N., Jørgensen, J. M. B., Nyengaard, J. R., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Nutrients. 10, 6, 749.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Echocardiographic assessment of left ventricular function in mitral regurgitation: is the dog a useful model of man?

    Zois, N. E., Pedersen, H. D., Häggström, J. & Olsen, Lisbeth Høier, 2014, In: Cardiovascular Endocrinology. 3, 1, p. 9-14 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    Effect of ES products from Anisakis (Nematoda: Anisakidae) on experimentally induced colitis in adult zebrafish

    Haarder, S., Kania, Per, Holm, T., Jørgensen, Louise von Gersdorff & Buchmann, Kurt, 2017, In: Parasite Immunology. 39, 10, 8 p., e12456.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Effect of High Inspiratory Oxygen Fraction on Endothelial Dysfunction in Healthy Volunteers: A Randomized Controlled Cross-over Pilot Study

    Larsen, M. H. H., Ekeløf, S., Kokotovic, D., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Gögenur, I., 2017, In: Anesthesia and Analgesia. 125, 5, p. 1793–1796

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Effect of Remote Ischaemic Preconditioning on Perioperative Endothelial Dysfunction in Non-Cardiac Surgery: A Randomised Clinical Trial

    Wahlstrøm, K. L., Hansen, H. F., Kvist, M., Burcharth, Jakob, Lykkesfeldt, Jens, Gögenur, Ismail & Ekeloef, S., 2023, In: Cells. 12, 6, 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Effect of Repeated Exposure to Isoflurane on Nest Building and Burrowing in Mice

    Gjendal, K., Ottesen, J. L., Olsson, I. A. S. & Sørensen, Dorte Bratbo, 2020, In: Journal of the American Association for Laboratory Animal Science : JAALAS. 59, 1, p. 30-36 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Effect of antioxidant supplementation on insulin sensitivity in response to endurance exercise training

    Yfanti, C., Nielsen, A. R., Åkerström, T., Nielsen, S., Rose, A. J., Richter, Erik A., Lykkesfeldt, Jens, Fischer, C. P. & Pedersen, Bente Klarlund, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 300, 5, p. E761-E770 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Effect of early-life gut mucosal compromise on disease progression in NOD mice

    Bendtsen, K. M., Hansen, Camilla Hartmann Friis, Krych, Lukasz, Buschard, K., Farlov, H. & Hansen, Axel Kornerup, 2017, In: Comparative Medicine. 67, 5, p. 388-399 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Effect of gluten-free diet and antibiotics on murine gut microbiota and immune response to tetanus vaccination

    Kihl, Pernille, Krych, Lukasz, Deng, Ling, Hansen, Lars Hestbjerg, Buschard, K., Skov, Søren, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: Plos One. 17, 4, 21 p., e0266719.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Effect of inoculating C57BL/6NTac mice with different gut microbiotas on gut colonization and glucose tolerance

    Ellekilde, M., Viscardi, M., Rune, Ida, Vogensen, Finn Kvist, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 1 Nov 2011. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research

  34. Published

    Effect of insulin on natriuretic peptide gene expression in porcine heart

    Terzic, D., Zois, N. E., Hunter, I., Christoffersen, Christina, Plomgaard, Peter Stendahl, Olsen, Lisbeth Høier, Jørgensen, Stine Ringholm, Pilegaard, Henriette & Goetze, Jens P. , 2020, In: Peptides. 131, 10 p., 170370.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Effect of insulin-induced hypoglycaemia on the central nervous system: evidence from experimental studies

    Jensen, Vivi Flou Hjorth, Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 3, p. 123-150 28 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Effect of insulin-induced hypoglycaemia on the peripheral nervous system: focus on adaptive mechanisms, pathogenesis and histopathological changes

    Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 8, p. 482-496 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Effect of maternal hypoglycaemia during gestation on materno-foetal nutrient transfer and embryo-foetal development: Evidence from experimental studies focused primarily on the rat

    Jensen, Vivi Flou Hjorth, Mølck, A. M., Lykkesfeldt, Jens & Bøgh, I. B., Apr 2018, In: Reproductive Toxicology. 77, p. 1-24 24 p.

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    Effect of melatonin on human nighttime endotoxaemia: randomized, double-blinded, cross-over study

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, 6, p. 1057-1063 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Effect of the sodium-glucose cotransporter-2 inhibitor dapagliflozinon platelet aggregation response in Cavalier King Charles Spanielswith and without cardiac disease

    Speitzer, A., Øgelund, E., Reimann, Maria Josefine, Møller, J. E., Skovsted, G. F., Lyhne, Mille Kronborg, Verma, S., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2022, In: Journal of Veterinary Internal Medicine. 36, 6, p. 2473 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  40. Published

    Effect of vitamin C and iron chelation on diesel exhaust particle and carbon black induced oxidative damage and cell adhesion molecule expression in human endothelial cells

    Frikke-Schmidt, H. R., Roursgaard, Martin, Lykkesfeldt, Jens, Loft, Steffen, Nøjgaard, J. K. & Møller, Peter, 2011, In: Toxicology Letters. 203, 3, p. 181-189 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Effects of exercise and dietary protein sources on adiposity and insulin sensitivity in obese mice

    Fjære, E., Myrmel, L. S., Lützhøft, Ditte Olsen, Andersen, H., Holm, J. B., Kiilerich, P., Hannisdal, R., Liaset, B., Kristiansen, Karsten & Madsen, L., 2019, In: Journal of Nutritional Biochemistry. 66, p. 98-109

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Effects of two- and twelve-weeks sodium-glucose cotransporter 2 inhibition on DNA and RNA oxidation: two randomized, placebo-controlled trials

    Larsen, E. L., Andersen, A., Kjær, L. K., Eickhoff, M. K., Frimodt-Møller, M., Persson, F., Rossing, Peter, Lykkesfeldt, Jens, Knop, Filip Krag, Vilsbøll, Tina, Rungby, Jørgen & Poulsen, Henrik Enghusen, 2023, In: Free Radical Research. 57, 2, p. 140-151

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Efficacy of Elimination of Pasteurella pneumotropica from a Mouse Specific Pathogen-Free Barrier Breeding Unit through Treatment with Enrofloxacin

    Østergaard, Grete, Arnorsdottir, S. E., Schumacher-Petersen, Camilla, Bundgaard, C. J., Koch, J. & Hau, Jann, 2010, In: JAALAS - Journal of the American Association for Laboratory Animal Science. 49, 5, p. 671-671 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  44. Published

    Efficacy of fibroblast growth factor 21 in non-alcoholic fatty liver disease in guinea pigs

    Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Basic & Clinical Pharmacology & Toxicology. 130, 3, p. 385-393

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Electrocardiography and heart rate variability in Göttingen Minipigs: Impact of diurnal variation, lead placement, repeatability and streptozotocin-induced diabetes

    Lyhne, Mille Kronborg, Debes, Karina Poulsdóttir, Helgogaard, T., Vegge, A., Kildegaard, J., Pedersen-Bjergaard, Ulrik & Olsen, Lisbeth Høier, 2022, In: Journal of Pharmacological and Toxicological Methods. 118, 107221.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Elimination of ascorbic acid after high-dose infusion in prostate cancer patients: a pharmacokinetic evaluation

    Nielsen, Torben Kjær, Højgaard, M., Andersen, J. T. T., Poulsen, Henrik Enghusen, Lykkesfeldt, Jens & Mikines, K. J., 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 4, p. 343-348 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Endothelial cell death and intimal foam cell accumulation in the coronary artery of infected hypercholesterolemic minipigs

    Birck, M. M., Saraste, A., Hyttel, P., Odermarsky, M., Liuba, P., Saukko, P., Hansen, Axel Kornerup & Pesonen, E., 2013, In: Journal of Cardiovascular Translational Research. 6, 4, p. 579-587 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Endothelial dysfunction and myocardial injury after major emergency abdominal surgery: a prospective cohort study

    Ekeloef, S., Oreskov, J. O., Falkenberg, A., Burcharth, J., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Gögenur, Ismail, 2020, In: BMC Anesthesiology. 20, 9 p., 67.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Endothelial dysfunction in the early postoperative period after major colon cancer surgery.

    Ekeløf, S., Larsen, M. H., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, Feb 2017, In: British Journal of Anaesthesia. 118, 2, p. 200-206

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Endothelin-1 and endothelin-3 regulate endothelin receptor expression in rat coronary arteries

    Skovsted, Gry Freja, Kilic, S. & Edvinsson, L., 2015, In: Basic & Clinical Pharmacology & Toxicology Online. 117, 5, p. 297-305 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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