- 2020
- Published
Myocardial Changes in Diabetic and Nondiabetic Nonhuman Primates
Krog, S., Ludvigsen, Trine Pagh, Nielsen, O. L., Kirk, R. K., Lykkegaard, K., Wulff, E. M., Møller, J. E., Pedersen, H. D. & Olsen, Lisbeth Høier, 2020, In: Veterinary Pathology. 57, 2, p. 332-343 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the effect of vitamin C intake on human health: How to (mis)interprete the clinical evidence
Lykkesfeldt, Jens, 2020, In: Redox Biology. 34, 13 p., 101532.Research output: Contribution to journal › Review › Research › peer-review
- Published
Pharmacokinetics of Repeated Oral Dosing with Coenzyme Q10 in Cavalier King Charles Spaniels with Myxomatous Mitral Valve Disease
Christiansen, L. B., Morsing, Malene Kjelin, Reimann, Maria Josefine, Martinussen, Torben, Birlie, Z., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2020, In: Antioxidants. 9, 9 p., 827.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteoglycan synthesis rate as a novel method to measure blood-induced cartilage degeneration in non-haemophilic and haemophilic rats
Pulles, A. E., Vøls, Kåre Kryger, Christensen, K. R., Coeleveld, K., Hansen, Axel Kornerup, van Vulpen, L. F. D., Petersen, M., Mastbergen, S. C., Roepstorff, K., Schutgens, R. E. G., Kjelgaard-Hansen, M. & Lafeber, F. P. J. G., 2020, In: Haemophilia. 26, 3, p. e88-e96Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice
Zakariassen, Hannah Louise, John, L. M., Lykkesfeldt, Jens, Raun, K., Glendorf, T., Schaffer, L., Lundh, S., Secher, A., Lutz, T. A. & Le Foll, C., 2020, In: Neuropharmacology. 167, 107987.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subcutaneous Administration of Insulin is Associated With Regional Differences in Injection Depot Variability and Kinetics in The Rat
Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Lykkesfeldt, Jens, Brockhoff, P. M. B., Seested, T. & Refsgaard, H. H. F., 2020, In: Experimental and Clinical Endocrinology and Diabetes. 128, 5, p. 332-338 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TL1A regulates adipose-resident innate lymphoid immune responses and enables diet-induced obesity in mice
Tougaard, P., Martinsen, L. O., Lützhøft, Ditte Olsen, Jensen, Henrik Elvang, Flethøj, M., Vandenabeele, P., Pedersen, Anders Elm, Skov, Søren, Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2020, In: International journal of obesity (2005). 44, p. 1062–1074Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The expression signatures in liver and adipose tissue from obese Göttingen Minipigs reveal a predisposition for healthy fat accumulation
Cirera, Susanna, Taşöz, E., Juul Jacobsen, M., Schumacher-Petersen, Camilla, Østergaard Christoffersen, B., Kaae Kirk, R., Pagh Ludvigsen, T., Hvid, H., Duelund Pedersen, H., Olsen, Lisbeth Høier & Fredholm, Merete, 2020, In: Nutrition and Diabetes. 10, 1, 12 p., 9.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The potential of human milk oligosaccharides to impact the microbiota-gut-brain axis through modulation of the gut microbiota
Al-Khafaji, A. H., Jepsen, Stine Dam, Christensen, K. R. & Vigsnæs, L. K., 2020, In: Journal of Functional Foods. 74, 104176.Research output: Contribution to journal › Review › Research › peer-review
- Published
Variation in diagnostic NAFLD/NASH read-outs in paired liver samples from rodent models
Jensen, Victoria Svop, Tveden-Nyborg, Pernille, Zacho-Rasmussen, C., Quaade, Michelle Lauge, Ipsen, David Højland, Hvid, H., Fledelius, C., Wulff, E. M. & Lykkesfeldt, Jens, 2020, In: Journal of Pharmacological and Toxicological Methods. 101, 9 p., 106651.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes
Gillberg, Linn, mxz703, mxz703, Nasif, A., Ohtani, H., Madaj, Z., Hansen, Jakob Werner, Rapin, N., Mogensen, J. B., Liu, M., Dufva, I. H., Lykkesfeldt, Jens, Hajkova, P., Jones, P. A. & Grønbæk, Kirsten, 17 Oct 2019, In: Clinical Epigenetics. 11, 1, p. 143-153 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Burrowing and nest building activity in mice after exposure to grid floor, isoflurane or ip injections
Gjendal, K., Ottesen, J. L., Olsson, I. A. S. & Sørensen, Dorte Bratbo, 1 Jul 2019, In: Physiology and Behavior. 206, p. 59-66 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A role of peroxisome proliferator-activated receptor gamma in non-alcoholic fatty liver disease
Skat-Rørdam, Josephine, Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, May 2019, In: Basic & Clinical Pharmacology & Toxicology. 124, 5, p. 528-537Research output: Contribution to journal › Review › Research › peer-review
- Published
Peri-operative endothelial dysfunction in patients undergoing minor abdominal surgery: An observational study
Busch, S. V. E., Godthaab, C., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Gögenur, I., Feb 2019, In: European Journal of Anaesthesiology. 36, 2, p. 130-134 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
18F-FDG PET/MR-imaging in a Göttingen Minipig model of atherosclerosis: Correlations with histology and quantitative gene expression
Ludvigsen, T. P., Pedersen, S. F., Vegge, A., Ripa, Rasmus Sejersten, Johannesen, H. H., Hansen, Adam Espe, Löfgren, J., Schumacher-Petersen, Camilla, Kirk, R. K., Pedersen, H. D., Christoffersen, B. Ø., Ørbæk, M., Forman, Julie Lyng, Klausen, T. L., Olsen, Lisbeth Høier & Kjær, Andreas, 2019, In: Atherosclerosis. 285, p. 55-63 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An ELISA for detection of complement-bound circulating immune complexes in mice
Boysen, L., Lauritzen, B., Viuff, B. M., Lykkesfeldt, Jens & Landsy, L. H., 2019, In: Journal of Immunotoxicology. 16, 1, p. 82-86 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Analytical validation of a conventional cardiac troponin I assay for dogs and cats
Langhorn, Rebecca, Yrfelt, J. D., Stjernegaard, C. S., Christiansen, L. B., Olsen, Lisbeth Høier & Nielsen, Lise Nikolic, 2019, In: Veterinary Clinical Pathology. p. 36-41Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antioxidant supplementation for lung disease in cystic fibrosis
Ciofu, Oana, Smith, S. & Lykkesfeldt, Jens, 2019, In: Cochrane Database of Systematic Reviews. 2019, 10, CD007020.Research output: Contribution to journal › Review › Research › peer-review
- Published
Atorvastatin and vitamin e accelerates NASH resolution by dietary intervention in a preclinical guinea pig model
Klaebel, J. H., Skjødt, M., Skat-Rørdam, Josephine, Rakipovski, G., Ipsen, David Højland, Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 11, 20 p., 2834.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bleed volume of experimental knee haemarthrosis correlates with the subsequent degree of haemophilic arthropathy
Vøls, Kåre Kryger, Kjelgaard-Hansen, M., Ley, C. D., Hansen, Axel Kornerup & Petersen, M., 2019, In: Haemophilia. 25, 2, p. 324-333 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cross-species reactive monoclonal antibodies against the extracellular domains of the insulin receptor and IGF1 receptor
Ørstrup, Laura Kofoed Hvidsten, Slaaby, R., Rasch, M. G., Rasmussen, N., Lund, S., Brandt, J., Schluckebier, G., Wang, Z., Lützen, A., Pedersen, T. Å., Hvid, H., Hansen, B. F. & Blume, N., 2019, In: Journal of Immunological Methods. 465, p. 20-26 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Delayed insulin absorption correlates with alterations in subcutaneous depot kinetics in rats with diet‐induced obesity
Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Brockhoff, P. M. B., Seested, T., Lykkesfeldt, Jens & Refsgaard, H. H. F., 2019, In: Obesity Science & Practice. 5, 3, p. 281-288Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of reduced and oxidized coenzyme Q10 in canine plasma and heart tissue by HPLC-ECD: Comparison with LC-MS/MS quantification
Schou-Pedersen, A. M. V., Schemeth, D. & Lykkesfeldt, Jens, 2019, In: Antioxidants. 8, 8, 253.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary LPS traces influences disease expression of the diet-induced obese mouse
Lindenberg, F. C. B., Ellekilde, M., Thörn, A. C., Kihl, Pernille, Larsen, C. S., Hansen, Camilla Hartmann Friis, Metzdorff, S. B., Aalbæk, Bent & Hansen, Axel Kornerup, 2019, In: Research in Veterinary Science. 123, p. 195-203 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of exercise and dietary protein sources on adiposity and insulin sensitivity in obese mice
Fjære, E., Myrmel, L. S., Lützhøft, Ditte Olsen, Andersen, H., Holm, J. B., Kiilerich, P., Hannisdal, R., Liaset, B., Kristiansen, Karsten & Madsen, L., 2019, In: Journal of Nutritional Biochemistry. 66, p. 98-109Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Experimental non-alcoholic steatohepatitis in Göttingen Minipigs: Consequences of high fat-fructose-cholesterol diet and diabetes
Schumacher-Petersen, Camilla, Christoffersen, B. O., Kirk, R. K., Ludvigsen, T. P., Zois, N. E., Pedersen, H. D., Vyberg, M. & Olsen, Lisbeth Høier, 2019, In: Journal of Translational Medicine. 17, 1, 110.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of endothelin type B receptors in uterine artery smooth muscle cells from pregnant Guinea pigs
Skovsted, Gry Freja, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2019, In: Placenta. 77, p. 8-15 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Formation and glomerular deposition of immune complexes in mice administered bovine serum albumin: Evaluation of dose, frequency, and biomarkers
Boysen, L., Viuff, B. M., Landsy, L. H., Price, S. A., Raymond, J. T., Lykkesfeldt, Jens & Lauritzen, B., 2019, In: Journal of Immunotoxicology. 16, 1, p. 191-200 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Generic immune complex assay for detection of murine anti-drug-antibodies in complex with human IgG
Boysen, L., Sprinkel, A. M. E., Lauritzen, B., Breinholt, J., Lykkesfeldt, Jens, Viuff, B. M. & Landsy, L. H., 2019, In: Biologicals. 60, p. 42-48 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycemic control during pregnancy — A predictor of vitamin C status at labor in type 1 diabeticwomen?
Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, 2019, In: Antioxidants. 8, 6, 153.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyperglycemia-induced transcriptional regulation of ROCK1 and TGM2 expression is involved in small artery remodeling in obese diabetic Göttingen Minipigs
Ludvigsen, T. P., Olsen, Lisbeth Høier, Pedersen, H. D., Østergaard Christoffersen, B. & Jensen, Lars Jørn, 2019, In: Clinical Science. 133, 24, p. 2499–2516 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular drivers of non-alcoholic steatohepatitis are sustained in mild-to-late fibrosis progression in a guinea pig model
Ipsen, David Højland, Skat-Rørdam, Josephine, Tsamouri, M. M., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Molecular Genetics and Genomics. 294, 3, p. 649–661Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myxømatøs mitralklapsygdom hos hund: Medicinsk behandling
Reimann, Maria Josefine, Christiansen, L. B., Falk, B. T. & Olsen, Lisbeth Høier, 2019, In: Dansk Veterinaertidsskrift. 2019, 11, p. 38-43Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myxømatøs mitralklapsygdom hos hund: Metoder til diagnostik af behandlingskrævende sygdomsstadier
Reimann, Maria Josefine, Christiansen, L. B., Falk, T. & Olsen, Lisbeth Høier, 2019, In: Dansk Veterinaertidsskrift. 2019, 9, p. 28-32Research output: Contribution to journal › Review › Research › peer-review
- Published
Når leveren bliver for fed
Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Aktuel Naturvidenskab. 2019, 3, p. 28-31Research output: Contribution to journal › Journal article › Communication
- Published
Oral LPS Dosing Induces Local Immunological Changes in the Pancreatic Lymph Nodes in Mice
Kihl, Pernille, Krych, Lukasz, Deng, Ling, Kildemoes, A. O., Laigaard, A., Hansen, L. H., Hansen, Camilla Hartmann Friis, Buschard, K., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2019, In: Journal of Diabetes Research. 2019, 9 p., 1649279.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rapid inflammation and early degeneration of bone and cartilage revealed in a time-course study of induced haemarthrosis in haemophilic rats
Christensen, K. R., Kjelgaard-Hansen, M., Nielsen, Lise Nikolic, Wiinberg, B., Althoehn, F. A., Poulsen, N. B., Vøls, Kåre Kryger, Thyme, A. P., Lovgren, K. M., Hansen, Axel Kornerup & Roepstorff, K., 2019, In: Rheumatology. 58, 4, p. 588-599Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced early life mucosal integrity decreases thymic cell counts and increases local, but not thymic regulatory, T cell recruitment: Gut mucosal integrity breach and thymic T cells
Zakariassen, Hannah Louise, Bendtsen, K. M., Tougaard, P. & Hansen, Axel Kornerup, 2019, In: European Journal of Inflammation. 17, p. 1-16Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short communication: Gut microbial colonization of the mouse colon using faecal transfer was equally effective when comparing rectal inoculation and oral inoculation based on 16S rRNA sequencing
Lützhøft, Ditte Olsen, Sánchez-Alcoholado, L., Tougaard, P., Mentzel, Caroline M. Junker, Kot, Witold, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2019, In: Research in Veterinary Science. 126, p. 227-232 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Telomere length and genotoxicity in the lung of rats following intragastric exposure to food-grade titanium dioxide and vegetable carbon particles
Jensen, Ditte Marie, Løhr, M., Sheykhzade, Majid, Lykkesfeldt, Jens, Wils, Regitze Sølling, Loft, Steffen & Møller, Peter, 2019, In: Mutagenesis. 34, 2, p. 203-214 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Pharmacokinetics of Vitamin C
Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 10, 20 p., 2412.Research output: Contribution to journal › Review › Research › peer-review
- Published
The effect of melatonin on endothelial dysfunction in patients after acute coronary syndrome: The MEFACS randomized clinical trial
Zahid, J. A., Isbrand, A., Kleif, J., Schou-Pedersen, A. V., Lykkesfeldt, Jens, Madsen, M. T. & Gögenur, Ismail, 2019, In: Journal of Pineal Research. 67, 3, e12600.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Towards a Göttingen minipig model of adult onset growth hormone deficiency: evaluation of stereotactic electrocoagulation method
Ørstrup, Laura Kofoed Hvidsten, Tvilling, L., Orlowski, D., Zaer, H., Bjarkam, C. R., von Voss, P., Andersen, P. S., Christoffersen, B., Hedemann Sørensen, J. C., Laursen, T., Thygesen, P., Lykkesfeldt, Jens & Glud, A. N., 2019, In: Heliyon. 5, 11, 8 p., e02892.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Urine 5-hydroxyindoleacetic acid in Cavalier King Charles spaniels with preclinical myxomatous mitral valve disease
Christiansen, L. B., Cremer, Signe Emilie, Helander, A., Madsen, T., Reimann, Maria Josefine, Møller, J. E., Höglund, K., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2019, In: Veterinary Journal. 250, p. 36-43 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Cardiac procholecystokinin expression during haemodynamic changes in the mammalian heart
Goetze, Jens P. , Hunter, I., Zois, N. E., Terzic, D., Valeur, N., Olsen, Lisbeth Høier, Smith, J., Plomgaard, Peter Stendahl, Hansen, L. H., Rehfeld, Jens Frederik, Balling, L. & Gustafsson, Finn, Oct 2018, In: Peptides. 108, p. 7-13 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural remodeling in cerebral and mesenteric arteries from obese Göttingen minipigs with or without diabetes
Ludvigsen, Trine Pagh, Olsen, Lisbeth Høier, Pedersen, H. D., Østergaard Christoffersen, B. & Jensen, Lars Jørn, 13 Sep 2018, p. 467P-468P . 2 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Analytical validation of a flow cytometric protocol for quantification of platelet microparticles in dogs
Cremer, Signe Emilie, Krogh, Anne Kirstine Havnsøe, Hedström, M. E. K., Christiansen, L. B., Tarnow, I. & Kristensen, Annemarie T., Jun 2018, In: Veterinary Clinical Pathology. 47, 2, p. 186-196 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluating IL-21 as a Potential Therapeutic Target in Crohn's Disease
Lindebo Holm, T., Tornehave, D., Søndergaard, H., Kvist, P. H., Sondergaard, B., Hansen, L., Hermit, M. B., Holgersen, Kristine, Vergo , S., Frederiksen , K. S., Haase, C. & Lundsgaard, D., 10 Apr 2018, In: Gastroenterology Research and Practice. 2018, 22 p., 5962624.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of maternal hypoglycaemia during gestation on materno-foetal nutrient transfer and embryo-foetal development: Evidence from experimental studies focused primarily on the rat
Jensen, Vivi Flou Hjorth, Mølck, A. M., Lykkesfeldt, Jens & Bøgh, I. B., Apr 2018, In: Reproductive Toxicology. 77, p. 1-24 24 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by ternary complex factors and the actin cytoskeleton
Krawczyk, K. K., Skovsted, Gry Freja, Perisic, L., Rippe, C., Dreier, R., Berg, J. O., Lykkesfeldt, Jens, Hedin, U. & Sward, K., Apr 2018.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Long-term diet-induced hypertension in rats is associated with reduced expression and function of small artery SKCa, IKCa, and Kir2.1 channels
Gradel, Anna Katrina Jógvansdóttir, Salomonsson, M., Sorensen, Charlotte Mehlin, von Holstein-Rathlou, Niels-Henrik & Jensen, Lars Jørn, 28 Feb 2018, In: Clinical Science. 132, 4, p. 461–474 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vasomotor function in rat arteries after ex vivo and intragastric exposure to food-grade titanium dioxide and vegetable carbon particles
Jensen, Ditte Marie, Christophersen, D. V., Sheykhzade, Majid, Skovsted, Gry Freja, Lykkesfeldt, Jens, Münter, R., Roursgaard, Martin, Loft, Steffen & Møller, Peter, 26 Feb 2018, In: Particle and Fibre Toxicology. 15, p. 1-18 12.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of Three Sample Preparation Procedures for the Quantification of L-Arginine, Asymmetric Dimethylarginine, and Symmetric Dimethylarginine in Human Plasma Using HPLC-FLD
Schou-Pedersen, A. M. V. & Lykkesfeldt, Jens, 1 Feb 2018, In: Journal of Analytical Methods in Chemistry. 2018, 7 p., 6148515.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proximal Neuropathy and Associated Skeletal Muscle Changes Resembling Denervation Atrophy in Hindlimbs of Chronic Hypoglycaemic Rats
Jensen, Vivi Flou Hjorth, Molck, A. M., Soeborg, H., Nowak, J., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., Jan 2018, In: Basic & Clinical Pharmacology & Toxicology. 122, 1, p. 165-175Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Symmetric Dimethylarginine in Cats with Hypertrophic Cardiomyopathy and Diabetes Mellitus
Langhorn, Rebecca, Kieler, Ida Nordang, Koch, Jørgen, Christiansen, L. B. & Jessen, Lisbeth Rem, Jan 2018, In: Journal of Veterinary Internal Medicine. 32, 1, p. 57-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A cafeteria diet alters the decision making strategy and metabolic markers in Sprague-Dawley male rats
Virtuoso, Alessandro, Forkman, Björn, Sarruf, D. A., Tveden-Nyborg, Pernille & Sørensen, Dorte Bratbo, 2018, In: Applied Animal Behaviour Science. 199, p. 35-44 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Abrogating fibrinolysis does not improve bleeding or rFVIIa/rFVIII treatment in a non-mucosal venous injury model in haemophilic rodents
Stagaard, R., Flick, M. J., Bojko, B., Goryński, K., Goryńska, P. Z., Ley, C. D., Olsen, Lisbeth Høier & Knudsen, T., 2018, In: Journal of Thrombosis and Haemostasis. 16, 7, p. 1369-1382 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Absence of functional compensation between coagulation factor VIII and plasminogen in double-knockout mice
Stagaard, R., Ley, C. D., Almholt, K., Olsen, Lisbeth Høier, Knudsen, T. & Flick, M. J., 2018, In: Blood advances. 2, 22, p. 3126-3136 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Early Life Mucosal Insult Temporarily Decreases Acute Oxazolone-Induced Inflammation in Mice
Bendtsen, K. M., Tougaard, P. & Hansen, Axel Kornerup, 2018, In: Inflammation. 41, 4, p. 1437-1447 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Angiotensin-converting enzyme activity in Cavalier King Charles Spaniels with an ACE gene polymorphism and myxomatous mitral valve disease
Meurs, K. M., Olsen, Lisbeth Høier, Reimann, Maria Josefine, Keene, B. W., Atkins, C. E., Adin, D., Aona, B., Condit, J., Defrancesco, T., Reina-Doreste, Y., Stern, J. A., Tou, S., Ward, J. & Woodruff, K., 2018, In: Pharmacogenetics and Genomics. 28, 2, p. 37-40 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies
Tveden-Nyborg, Pernille, Bergmann, T. K. & Lykkesfeldt, Jens, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 233-235 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Biochemical and cognitive effects of docosahexaenoic acid differ in a developmental and SorLA dependent manner
Højland, A., Richner, M., Mølgaard, S., Dieu, R. S., Eskelund, A., Nykjær, A., Nyengaard, J. R., Lykkesfeldt, Jens, Glerup, S. & Nielsen, M. S., 2018, In: Behavioural Brain Research. 348, p. 90-100 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deregulation of obesity-relevant genes is associated with progression in BMI and the amount of adipose tissue in pigs
Mentzel, Caroline M. Junker, Cardoso, T. F., Pipper, C. B., Jacobsen, M. J., Jørgensen, Claus Bøttcher, Cirera, Susanna & Fredholm, Merete, 2018, In: Molecular Genetics and Genomics. 293, 1, p. 129–136 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary fat stimulates development of NAFLD more potently than dietary fructose in Sprague-Dawley rats
Jensen, Victoria Svop, Hvid, H., Damgaard, J., Nygaard, H., Ingvorsen, C., Wulff, E. M., Lykkesfeldt, Jens & Fledelius, C., 2018, In: Diabetology and Metabolic Syndrome. 10, 13 p., 4.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary normalization from a fat, fructose and cholesterol-rich diet to chow limits the amount of myocardial collagen in a Göttingen Minipig model of obesity
Andreasen, L. J., Krog, S., Ludvigsen, T. P., Nielsen, O. L., Møller, J. E., Christoffersen, B. Ø., Pedersen, H. D. & Olsen, Lisbeth Høier, 2018, In: Nutrition and Metabolism. 15, 64.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does colour matter? Preference of mice for different colours of the house mouse igloo: An observational study
Gjendal, K., Ottesen, J. L. & Sørensen, Dorte Bratbo, 2018, In: Scandinavian Journal of Laboratory Animal Science. 44, 6.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early life vitamin C deficiency does not alter morphology of hippocampal CA1 pyramidal neurons or markers of synaptic plasticity in a Guinea pig model
Hansen, S. N., Jørgensen, J. M. B., Nyengaard, J. R., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Nutrients. 10, 6, 749.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by MKL2, ternary complex factors, and actin dynamics
Krawczyk, K. K., Skovsted, Gry Freja, Perisic, L., Dreier, R., Berg, Jais Oliver, Hedin, U., Rippe, C. & Swärd, K., 2018, In: American Journal of Physiology - Cell Physiology. 315, 6, p. C873-C884Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Eye, body or tail? Thermography as a measure of stress in mice
Gjendal, K., Franco, N. H., Ottesen, J. L., Sørensen, Dorte Bratbo & Olsson, I. A. S., 2018, In: Physiology and Behavior. 196, p. 135-143 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability
Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Lykkesfeldt, Jens, Seested, T., Gram-Nielsen, S., Kristensen, N. R. & Refsgaard, H., 2018, In: Journal of Diabetes Research. 2018, 17 p., 1205121.Research output: Contribution to journal › Review › Research › peer-review
- Published
Gut microbiota recovery and immune response in ampicillin-treated mice
Castro Mejia, J. L., Jakesevic, M., Fabricius, N. F., Krych, Lukasz, Nielsen, Dennis Sandris, Kot, W., Bendtsen, K. M. B., Vogensen, Finn Kvist, Hansen, Camilla Hartmann Friis & Hansen, Axel Kornerup, 2018, In: Research in Veterinary Science. 118, p. 357-364 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Have you tried spermine? A rapid and cost-effective method to eliminate dextran sodium sulfate inhibition of PCR and RT-PCR
Krych, Lukasz, Kot, W., Bendtsen, K. M. B., Hansen, Axel Kornerup, Vogensen, Finn Kvist & Nielsen, Dennis Sandris, 2018, In: Journal of Microbiological Methods. 144, p. 1-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity
Nasser, A., Møller, A. T., Hellmund, V., Thorborg, S. S., Jespersgaard, C., Bjerrum, Ole Jannik, Dupontd, E., Nachman, G., Lykkesfeldt, Jens, Jensen, T. S. & Møller, L. B., 2018, In: Pain. 159, 6, p. 1012-1024 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-fat feeding induces mobilization of vitamin C in obese prone rats
Tranberg, B., Hellgren, L. I., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2018, In: Research in Veterinary Science. 119, p. 167-169 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Holder C-vitamin dine blodkar sunde?
Skovsted, Gry Freja, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2018Research output: Other contribution › Net publication - Internet publication › Communication
- Published
Liraglutide Decreases Hepatic Inflammation and Injury in Advanced Lean Non-Alcoholic Steatohepatitis
Ipsen, David Højland, Rolin, B., Rakipovski, G., Skovsted, Gry Freja, Madsen, A., Kolstrup, S., Schou-Pedersen, A. M., Skat-Rørdam, Josephine, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 704-713Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long term Westernized diet leads to region-specific changes in brain signaling mechanisms
Hansen, S. N., Ipsen, David Højland, Schou-Pedersen, A. M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Neuroscience Letters. 676, p. 85-91 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics
Rune, Ida, Rolin, B., Lykkesfeldt, Jens, Nielsen, Dennis Sandris, Krych, Lukasz, Kanter, J. E., Bornfeldt, K. E., Kihl, Pernille, Buschard, K., Josefsen, K., Fels, J. J., Mortensen, A., Christoffersen, B., Kirk, R. K. & Hansen, Axel Kornerup, 2018, In: Scientific Reports. 8, 1, 12 p., 5416.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease
Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Cellular and Molecular Life Sciences. 75, 18, p. 3313-3327 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Oral insulin does not alter gut microbiota composition of NOD mice
Kihl, Pernille, Krych, Lukasz, Buschard, K., Wesley, J. D., Kot, W., Hansen, Axel Kornerup, Nielsen, Dennis Sandris & von Herrath, M. G., 2018, In: Diabetes/Metabolism Research and Reviews. 34, 6, 9 p., e3010.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of pannexin and adenosine triphosphate (ATP) following myocardial ischemia/reperfusion
Kristiansen, S. B., Skovsted, Gry Freja, Berchtold, L. A., Radziwon-Balicka, A., Dreisig, K., Edvinsson, L., Sheykhzade, Majid & Haanes, Kristian Agmund, 2018, In: Scandinavian Cardiovascular Journal. 52, 6, p. 340-343Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SK channel inhibition did not increase short-term variability of the QT intervals in atrial tachypaced pigs with left ventricular dysfunction in contrast to the positive control dofetilide
Citerni, C., Kirchhoff, J., Olsen, Lisbeth Høier, Gentilini, F., Forni, M., Zannoni, A., Edvardsson, N., Bentzen, B., Grunnet, M. & Diness, J., 2018, In: European Heart Journal. 39, S1, p. 809-809 P3811.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Spatial Memory Dysfunction Induced by Vitamin C Deficiency Is Associated with Changes in Monoaminergic Neurotransmitters and Aberrant Synapse Formation
Hansen, S. N., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Antioxidants. 7, 7, p. 11 82.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development
Rasmussen, K. K., Skat-Rørdam, Josephine, Andersen, P., Warzecha, C. B., Pye, M., Andersen, T. A., Ajbro, K. D., Bendsen, E., Narimatsu, M., Vilhardt, Frederik, Pedersen, Lotte Bang, Wrana, J. L., Anderson, R. H., Møllgård, Kjeld, Christensen, Søren Tvorup & Larsen, Lars Allan, 2018, In: Scientific Reports. 8, 1, 14 p., 9542.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice
Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, Ditte Olsen, Halling, Jens Frey, Hansen, M., Al-Soud, W. A., Hansen, Lars Hestbjerg, Kiilerich, P. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vasomotor dysfunction in human subcutaneous arteries exposed ex vivo to food-grade titanium dioxide
Jensen, Ditte Marie, Skovsted, Gry Freja, Lykkesfeldt, Jens, Dreier, R., Berg, J. O., Jeppesen, J. L., Sheykhzade, Majid, Loft, Steffen & Møller, Peter, 2018, In: Food and Chemical Toxicology. 120, p. 321-327 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Acute Haemarthrosis in the Haemophilia A Rat Generates a Local and Systemic Proinflammatory Response
Lovgren, K. M., Christensen, K. R., Majewski, W., Ostrup, O., Skov, Søren & Wiinberg, B., Nov 2017, In: Thrombosis and Haemostasis. 117, 11, p. 2092-2104Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hang on: An evaluation of the hemp rope as environmental enrichment in C57BL/6 mice
Gjendal, K., Sørensen, Dorte Bratbo, Kiersgaard, M. K. & Ottesen, J. L., Nov 2017, In: Animal Welfare. 26, 4, p. 437-447 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans: randomised, controlled trials
Larsen, E. L., Cejvanovic, V., Kjær, L. K., Pedersen, M. T., Popik, S. D., Hansen, L. K., Andersen, Jon Thor Trærup, Solem, Espen Victor Jimenez, Broedbaek, K., Petersen, M., Weimann, A., Henriksen, T., Lykkesfeldt, Jens, Torp-Pedersen, C. & Poulsen, Henrik Enghusen, Aug 2017, In: British Journal of Clinical Pharmacology. 83, 8, p. 1643-1653Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Toxicological Effects during and following Persistent Insulin-Induced Hypoglycaemia in Healthy Euglycaemic Rats
Jensen, Vivi Flou Hjorth, Molck, A., Berthelsen, L. O., Alifrangis, L., Andersen, L., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., Jul 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 1, p. 53-66Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pasteurization Procedures for Donor Human Milk Affect Body Growth, Intestinal Structure, and Resistance against Bacterial Infections in Preterm Pigs
Li, Y., Nguyen, Duc Ninh, de Waard, M., Christensen, Lars, Zhou, P., Jiang, Pingping, Sun, Jing, Bojesen, Anders Miki, Lauridsen, C., Lykkesfeldt, Jens, Dalsgaard, T. K., Bering, S. B. & Sangild, Per Torp, Jun 2017, In: Journal of Nutrition. 147, 6, p. 1121-1130Research output: Contribution to journal › Journal article › Research › peer-review
- Published
35Sulphate incorporation assay as a new tool for measuring early cartilage degradation following blood exposure in vitro and in vivo in f8 ko rats
Pulles, A. E., Christensen, K. R., Coeleveld, K., Kjelgaard-Hansen, M., Schutgens, R. E., Lafeber, F. P., Roepstorff, K. & Mastbergen, S. C., Apr 2017, In: Osteoarthritis and Cartilage. 25, S1, p. S156-S157Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ETB receptors via the protein kinase MEK-ERK1/2 signaling pathway in rat
Skovsted, Gry Freja, Kruse, L. S., Berchtold, L. A., Grell, A., Warfvinge, K. & Edvinsson, L., 1 Mar 2017, In: PLOS ONE. 12, 3, 18 p., e0174119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endothelial dysfunction in the early postoperative period after major colon cancer surgery.
Ekeløf, S., Larsen, M. H., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, Feb 2017, In: British Journal of Anaesthesia. 118, 2, p. 200-206Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma lipid oxidation predicts atherosclerotic status better than cholesterol in diabetic apolipoprotein E deficient mice
Petersen, Karen Ekkelund, Lykkesfeldt, Jens, Raun, K. & Rakipovski, G., Jan 2017, In: Experimental Biology and Medicine (Maywood). 242, 1, p. 88-91Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visualization of haemophilic arthropathy in F8(-/-) rats by ultrasonography and micro-computed tomography
Christensen, K. R., Roepstorff, K., Petersen, M., Wiinberg, B., Hansen, Axel Kornerup, Kjelgaard-Hansen, M. & Nielsen, L. N., Jan 2017, In: Haemophilia. 23, 1, 11 p., 152-162.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A porcine subcutaneous Staphylococcus aureus abscess model - a pilot study
Nielsen, O. L., Larsen, M. N., Frees, Dorte, Pedersen, M. M., Skov, Søren & Olsen, Lisbeth Høier, 2017.Research output: Contribution to conference › Conference abstract for conference › Communication
- Published
Assessment of implantable infusion pumps for continuous infusion of human insulin in rats: potential for group housing
Jensen, Vivi Flou Hjorth, Molck, A., Martensson, M., Strid, M. A., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: Laboratory Animals. 51, 3, p. 273-283Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic Hyperinsulinaemic Hypoglycaemia in Rats Is Accompanied by Increased Body Weight, Hyperleptinaemia, and Decreased Neuronal Glucose Transporter Levels in the Brain
Jensen, Vivi Flou Hjorth, Molck, A., Chapman, M., Alifrangis, L., Andersen, L., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: International Journal of Endocrinology. 2017, 14 p., 7861236.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of ES products from Anisakis (Nematoda: Anisakidae) on experimentally induced colitis in adult zebrafish
Haarder, S., Kania, Per, Holm, T., Jørgensen, Louise von Gersdorff & Buchmann, Kurt, 2017, In: Parasite Immunology. 39, 10, 8 p., e12456.Research output: Contribution to journal › Journal article › Research › peer-review
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Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
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Increased systemic oxidatively generated DNA and RNA damage in schizophrenia
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Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
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