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  1. Published

    TL1A regulates adipose-resident innate lymphoid immune responses and enables diet-induced obesity in mice

    Tougaard, P., Martinsen, L. O., Lützhøft, Ditte Olsen, Jensen, Henrik Elvang, Flethøj, M., Vandenabeele, P., Pedersen, Anders Elm, Skov, Søren, Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2020, In: International journal of obesity (2005). 44, p. 1062–1074

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Tail vein transection bleeding model in fully anesthetized hemophilia A mice

    Carol Illa, Ariadna, Baumgarten, S., Danielsen, D., Larsen, K., Elm, T., Johansen, P. B., Knudsen, T., Lauritzen, B., Tranholm, M. & Ley, C. D., 2021, In: Journal of Visualized Experiments. 175, 17 p., e62952.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Telomere length and genotoxicity in the lung of rats following intragastric exposure to food-grade titanium dioxide and vegetable carbon particles

    Jensen, Ditte Marie, Løhr, M., Sheykhzade, Majid, Lykkesfeldt, Jens, Wils, Regitze Sølling, Loft, Steffen & Møller, Peter, 2019, In: Mutagenesis. 34, 2, p. 203-214 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Temporal development of dyslipidemia and nonalcoholic fatty liver disease (Nafld) in syrian hamsters fed a high‐fat, high‐fructose, high‐cholesterol diet

    Jensen, Victoria Svop, Fledelius, C., Wulff, E. M., Lykkesfeldt, Jens & Hvid, H., 2021, In: Nutrients. 13, 2, p. 1-18 18 p., 604.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development

    Rasmussen, K. K., Skat-Rørdam, Josephine, Andersen, P., Warzecha, C. B., Pye, M., Andersen, T. A., Ajbro, K. D., Bendsen, E., Narimatsu, M., Vilhardt, Frederik, Pedersen, Lotte Bang, Wrana, J. L., Anderson, R. H., Møllgård, Kjeld, Christensen, Søren Tvorup & Larsen, Lars Allan, 2018, In: Scientific Reports. 8, 1, 14 p., 9542.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The F8(-/-) rat as a model of hemophilic arthropathy

    Christensen, K. R., Roepstorff, K., Wiinberg, B., Hansen, Axel Kornerup, Tranholm, M., Nielsen, Lise Nikolic & Kjelgaard-Hansen, M., Jun 2016, In: Journal of Thrombosis and Haemostasis. 14, 6, p. 1216-1225 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

    Callø, Kirstine, Geryk, M., Freude, Kristine, Treat, J. A., Vold, V. A., Frederiksen, Henriette Reventlow S, Broendberg, A. K., Frederiksen, T. C., Jensen, H. K. & Cordeiro, J. M., 2022, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 24, 12, p. 2015–2027

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The Pharmacokinetics of Vitamin C

    Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 10, 20 p., 2412.

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    The Zebra Fish IBD Model Assessed By Novel Probe Based TagMan Assays

    Kania, Per, Buchmann, Kurt & Haarder, S., 29 Jun 2015.

    Research output: Contribution to conference › Conference abstract for conference › Research

  10. Published

    The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers

    Nielsen, C. F., van Putten, S. M., Lund, I. K., Melander, M. C., Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Reckzeh, K., Christensen, K. R., Ingvarsen, S. Z., Gårdsvoll, Henrik, Jensen, K. E., Hamerlik, P., Engelholm, Lars Henning & Behrendt, Niels, 2017, In: OncoTarget. 8, 27, p. 44605-44624 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The counterregulatory response to hypoglycaemia in the pig

    Gradel, Anna Katrina Jógvansdóttir, Kildegaard, J., Ludvigsen, T. P., Porsgaard, T., Schou-Pedersen, A. M. V., Fels, J. J., Lykkesfeldt, Jens & Refsgaard, H. H. F., Oct 2020, In: Basic & Clinical Pharmacology & Toxicology. 127, 4, p. 278-286

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The development of nonalcoholic steatohepatitis is subjected to breeder dependent variation in guinea pigs

    Ipsen, David Højland, Agerskov, R. H., Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Scientific Reports. 11, 2955.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The dietary regulation of LEAP2 depends on meal composition in mice

    Gradel, Anna Katrina Jógvansdóttir, Holm, Stephanie Kjærulff, Byberg, Sarah, Merkestein, M., Hogendorf, W. F. J., Lund, M. L., Buijink, Jesse A., Damgaard, J., Lykkesfeldt, Jens & Holst, Birgitte, 2023, In: FASEB Journal. 37, 6, 21 p., 22923.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The effect of acetylsalicylic acid and pentoxifylline in guinea pigs with non-alcoholic steatohepatitis

    Ipsen, David Højland, Skat-Rørdam, Josephine, Svenningsen, M., Andersen, Mia Trein, Latta, M., Buelund, Lene Elisabeth, Lintrup, K., Skaarup, R., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 4, p. 583-593

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice

    Rune, Ida, Ellekilde, M., Hansen, Camilla Hartmann Friis, Nielsen, Dennis Sandris, Rolin, B. C., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2011. 1 p.

    Research output: Contribution to conference › Poster › Research

  16. Published

    The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice

    Rune, Ida, Nielsen, Dennis Sandris, Hansen, Axel Kornerup, Ellekilde, M., Lykkesfeldt, Jens, Hansen, Camilla Hartmann Friis & Rolin, B., Nov 2011. 1 p.

    Research output: Contribution to conference › Poster › Research

  17. Published

    The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice

    Rune, Ida, Hansen, Axel Kornerup, Ellekilde, M., Nielsen, Dennis Sandris & Hansen, C., Nov 2011. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research

  18. Published

    The effect of melatonin on endothelial dysfunction in patients after acute coronary syndrome: The MEFACS randomized clinical trial

    Zahid, J. A., Isbrand, A., Kleif, J., Schou-Pedersen, A. V., Lykkesfeldt, Jens, Madsen, M. T. & Gögenur, Ismail, 2019, In: Journal of Pineal Research. 67, 3, e12600.

    Research output: Contribution to journal › Letter › Research › peer-review

  19. Published

    The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study

    Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The expression signatures in liver and adipose tissue from obese Göttingen Minipigs reveal a predisposition for healthy fat accumulation

    Cirera, Susanna, Taşöz, E., Juul Jacobsen, M., Schumacher-Petersen, Camilla, Østergaard Christoffersen, B., Kaae Kirk, R., Pagh Ludvigsen, T., Hvid, H., Duelund Pedersen, H., Olsen, Lisbeth Høier & Fredholm, Merete, 2020, In: Nutrition and Diabetes. 10, 1, 12 p., 9.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The genetic consequences of dog breed formation - Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels: [+ correction]

    Axelsson, E., Ljungvall, I., Bhoumik, P., Conn, L. B., Muren, E., Ohlsson, Å., Olsen, L. H., Engdahl, K., Hagman, R., Hanson, J., Kryvokhyzha, D., Pettersson, M., Grenet, O., Moggs, J., Del Rio-Espinola, A., Epe, C., Taillon, B., Tawari, N., Mane, S., Hawkins, T. & 4 others, Hedhammar, Å., Gruet, P., Häggström, J. & Lindblad-Toh, K., 2021, In: PLOS Genetics. 17, 9, 34 p., e1009726.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice

    Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, Ditte Olsen, Halling, Jens Frey, Hansen, M., Al-Soud, W. A., Hansen, Lars Hestbjerg, Kiilerich, P. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The influence of the young microbiome on inflammatory diseases - lessons from animal studies

    Bendtsen, K. M. B., Fisker, L., Hansen, Axel Kornerup, Hansen, Camilla Hartmann Friis & Nielsen, Dennis Sandris, 2015, In: Birth Defects Research. Part C: Embryo Today Reviews (Print). 105, 4, p. 278-295 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    The intestinal permeability marker FITC-dextran 4kDa should be dosed according to lean body mass in obese mice

    Voetmann, Louise Marie, Rolin, B., Kirk, R. K., Pyke, C. & Hansen, Axel Kornerup, 2023, In: Nutrition and Diabetes. 13, 1.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The kidneys play a central role in the clearance of rhGH in rats

    Vestergaard, Bill, Thygesen, P., Kreilgaard, M., Fels, J. J., Lykkesfeldt, Jens & Agerso, H., 30 Apr 2016, In: European Journal of Pharmaceutical Sciences. 86, p. 29-33

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    The kidneys play an important role in the clearance of rFVIIa in rats

    Vestergaard, Bill, Appa, R. S., Lykkesfeldt, Jens & Agersø, H., 2014, In: Thrombosis Research. 133, 6, p. 1124-1129 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    The potential of human milk oligosaccharides to impact the microbiota-gut-brain axis through modulation of the gut microbiota

    Al-Khafaji, A. H., Jepsen, Stine Dam, Christensen, K. R. & Vigsnæs, L. K., 2020, In: Journal of Functional Foods. 74, 104176.

    Research output: Contribution to journal › Review › Research › peer-review

  28. Published

    The role of neutrophils and G-CSF in DNFB-induced contact hypersensitivity in mice

    Christensen, A. D., Skov, Søren & Haase, C., 2014, In: Immunity, Inflammation and Disease. 2, 1, p. 21-34 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    The role of vitamin C in epigenetic cancer therapy

    Mikkelsen, Stine Ulrik, Gillberg, Linn, Lykkesfeldt, Jens & Grønbæk, Kirsten, 2021, In: Free Radical Biology and Medicine. 170, p. 179-193 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Thick methacrylate sections devoid of lost caps simplify stereological quantifications based on the optical fractionator design

    Andersen, S. H., Lykkesfeldt, Jens & Larsen, J. O., 15 Sep 2015, In: Anatomical Record. 298, 12, p. 2141-2150 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Third-stage nematode larvae of Contracaecum osculatum from Baltic cod (Gadus morhua) elicit eosinophilic granulomatous reactions when penetrating the stomach mucosa of pigs

    Strøm, S. B., Haarder, S., Korbut, R., Mejer, H., Thamsborg, Stig Milan, Kania, Per & Buchmann, Kurt, 2015, In: Parasitology Research. 114, 3, p. 1217-1220 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Towards a Göttingen minipig model of adult onset growth hormone deficiency: evaluation of stereotactic electrocoagulation method

    Ørstrup, Laura Kofoed Hvidsten, Tvilling, L., Orlowski, D., Zaer, H., Bjarkam, C. R., von Voss, P., Andersen, P. S., Christoffersen, B., Hedemann Sørensen, J. C., Laursen, T., Thygesen, P., Lykkesfeldt, Jens & Glud, A. N., 2019, In: Heliyon. 5, 11, 8 p., e02892.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Toxicological Effects during and following Persistent Insulin-Induced Hypoglycaemia in Healthy Euglycaemic Rats

    Jensen, Vivi Flou Hjorth, Molck, A., Berthelsen, L. O., Alifrangis, L., Andersen, L., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., Jul 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 1, p. 53-66

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Transfer of gut microbiota from lean and obese mice to antibiotic-treated mice

    Ellekilde, M., Selfjord, E. M., Larsen, C. S., Jakesevic, M., Rune, Ida, Christensen, B. T., Vogensen, Finn Kvist, Nielsen, Dennis Sandris, Bahl, M. I., Licht, T. R., Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2014, In: Scientific Reports. 4, 8 p., 5922.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Translational aspects of rectal evoked potentials: a comparative study in rats and humans

    Nissen, T. D., Brock, C., Graversen, C., J. Coen, S., Hultin, L., Aziz, Q., Lykkesfeldt, Jens & Drewes, A. M., 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, p. G119-G128 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Treatment with anti-C5aR mAb leads to early-onset clinical and mechanistic effects in the murine delayed-type hypersensitivity arthritis model

    Atkinson, S. M., Nansen, A., Usher, P. A., Sondergaard, B., Mackay, C. R., Friedrichsen, B., Chang, C., Tang, R., Skov, Søren, Haase, C. & Hornum, L., Nov 2015, In: Autoimmunity. 48, 7, p. 460-470 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Urine 5-hydroxyindoleacetic acid in Cavalier King Charles spaniels with preclinical myxomatous mitral valve disease

    Christiansen, L. B., Cremer, Signe Emilie, Helander, A., Madsen, T., Reimann, Maria Josefine, Møller, J. E., Höglund, K., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2019, In: Veterinary Journal. 250, p. 36-43 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Validation of Piroxicam-Accelerated Colitis in the Interleukin-10 Knock out Mouse - a Preclinical Model Mimicking Human Inflammatory Bowel Disease

    Holgersen, Kristine, Kvist, P. H., Hansen, Axel Kornerup & Holm, T. L., May 2014.

    Research output: Contribution to conference › Poster › Research › peer-review

  39. E-pub ahead of print

    Validation of computed tomography as a diagnostic tool in guinea pigs with non-alcoholic fatty liver disease

    Lintrup, K., Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens, Tveden-Nyborg, Pernille & Buelund, Lene Elisabeth, 2024, (E-pub ahead of print) In: Laboratory Animals.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Variation in diagnostic NAFLD/NASH read-outs in paired liver samples from rodent models

    Jensen, Victoria Svop, Tveden-Nyborg, Pernille, Zacho-Rasmussen, C., Quaade, Michelle Lauge, Ipsen, David Højland, Hvid, H., Fledelius, C., Wulff, E. M. & Lykkesfeldt, Jens, 2020, In: Journal of Pharmacological and Toxicological Methods. 101, 9 p., 106651.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Vascular gene expression in diet-induced atherosclerotic Gottingen minipigs

    Christensen, Liv von Voss, Skovgaard, K., Ludvigsen, T. P., Kirk, R. K., Christoffersen, B. O., Pedersen, H. D., Heegaard, P. M. & Olsen, Lisbeth Høier, Jul 2015, In: Atherosclerosis. 241, 1, p. E85-E85 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  42. Published

    Vasomotor dysfunction in human subcutaneous arteries exposed ex vivo to food-grade titanium dioxide

    Jensen, Ditte Marie, Skovsted, Gry Freja, Lykkesfeldt, Jens, Dreier, R., Berg, J. O., Jeppesen, J. L., Sheykhzade, Majid, Loft, Steffen & Møller, Peter, 2018, In: Food and Chemical Toxicology. 120, p. 321-327 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Vasomotor function in rat arteries after ex vivo and intragastric exposure to food-grade titanium dioxide and vegetable carbon particles

    Jensen, Ditte Marie, Christophersen, D. V., Sheykhzade, Majid, Skovsted, Gry Freja, Lykkesfeldt, Jens, Münter, R., Roursgaard, Martin, Loft, Steffen & Møller, Peter, 26 Feb 2018, In: Particle and Fibre Toxicology. 15, p. 1-18 12.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Visualization of haemophilic arthropathy in F8(-/-) rats by ultrasonography and micro-computed tomography

    Christensen, K. R., Roepstorff, K., Petersen, M., Wiinberg, B., Hansen, Axel Kornerup, Kjelgaard-Hansen, M. & Nielsen, L. N., Jan 2017, In: Haemophilia. 23, 1, 11 p., 152-162.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Vitamin C: From Bench to Bedside

    Carr, A. C. & Lykkesfeldt, Jens, 2021, In: Nutrients. 13, 4, 3 p., 1102.

    Research output: Contribution to journal › Editorial › Research › peer-review

  46. Published

    Vitamin C

    Lykkesfeldt, Jens & Carr, A. C., Jan 2024, In: Advances in Nutrition. 15, 1, 100155.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Vitamin C

    Lykkesfeldt, Jens & Carr, A. C., Jan 2024, In: Advances in nutrition (Bethesda, Md.). 15, 1, p. 100155

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Vitamin C

    Lykkesfeldt, Jens, Michels, A. J. & Frei, B., 2014, In: Advances in Nutrition. 5, 1, p. 16-18 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Vitamin C - ascorbic acid

    Frikke-Schmidt, H., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens, Drake, V. J. & Frei, B., 28 Feb 2011, Vitamins in the Prevention of Human Diseases. Walter de Gruyter GmbH and Co. KG, p. 323-362 40 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  50. Published

    Vitamin C Deficiency Exacerbates Dysfunction of Atherosclerotic Coronary Arteries in Guinea Pigs Fed a High-Fat Diet

    Skovsted, Gry Freja, Skat-Rørdam, Josephine, Frøkiær, A. P., Jensen, Henrik Elvang, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2022, In: Antioxidants. 11, 11, 2226.

    Research output: Contribution to journal › Journal article › Research › peer-review

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