Lifepharm

  1. Published

    Asymmetric dimethylarginine in somatically healthy schizophrenia patients treated with atypical antipsychotics: a case-control study

    Jørgensen, Anders, Knorr, Ulla Benedichte Søsted, Soendergaard, M. G., Lykkesfeldt, Jens, Fink-Jensen, Anders, Poulsen, Henrik Enghusen, Jørgensen, Martin Balslev, Olsen, N. V. & Staalsø, J. M., 2015, In: B M C Psychiatry. 15, 8 p., 67.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Increased systemic oxidatively generated DNA and RNA damage in schizophrenia

    Jørgensen, A., Brødbæk, K., Fink-Jensen, Anders, Knorr, U., Greisen Søndergaard, M., Henriksen, T., Weimann, A., Jepsen, P., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen & Jørgensen, Martin Balslev, 2013, In: Psychiatry Research. 209, 3, p. 417–423 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Dietary magnesium deficiency affects gut microbiota and anxiety-like behaviour in C57BL/6N mice

    Jørgensen, B. M. P., Winther, G., Kihl, Pernille, Nielsen, Dennis Sandris, Wegener, G., Hansen, Axel Kornerup & Sørensen, Dorte Bratbo, 2015, In: Acta Neuropsychiatrica (Print). 27, 5, p. 307-311 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Cardiac adaptation in hibernating, free-ranging Scandinavian Brown Bears (Ursus arctos)

    Jørgensen, P. G., Evans, A., Kindberg, J., Olsen, Lisbeth Høier, Galatius, S. & Fröbert, O., 2020, In: Scientific Reports. 10, 1, 9 p., 247.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Distribution and time course of corticosterone excretion in faeces and urine of female mice with varying systemic concentrations

    Kalliokoski, Otto, Hau, Jann, Jacobsen, K. R., Schumacher-Petersen, Camilla & Abelson, Klas, 2010, In: General and Comparative Endocrinology. 168, 3, p. 450-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The Zebra Fish IBD Model Assessed By Novel Probe Based TagMan Assays

    Kania, Per, Buchmann, Kurt & Haarder, S., 29 Jun 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  7. Published

    Fgf21 regulates hepatic metabolic pathways to improve steatosis and inflammation

    Keinicke, H., Sun, G., Mentzel, Caroline M. Junker, Fredholm, Merete, John, L. M., Andersen, B., Raun, K. & Kjaergaard, M., 2020, In: Endocrine Connections. 9, 8, p. 755-768 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Oral insulin does not alter gut microbiota composition of NOD mice

    Kihl, Pernille, Krych, Lukasz, Buschard, K., Wesley, J. D., Kot, W., Hansen, Axel Kornerup, Nielsen, Dennis Sandris & von Herrath, M. G., 2018, In: Diabetes/Metabolism Research and Reviews. 34, 6, 9 p., e3010.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Oral LPS Dosing Induces Local Immunological Changes in the Pancreatic Lymph Nodes in Mice

    Kihl, Pernille, Krych, Lukasz, Deng, Ling, Kildemoes, A. O., Laigaard, A., Hansen, L. H., Hansen, Camilla Hartmann Friis, Buschard, K., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2019, In: Journal of Diabetes Research. 2019, 9 p., 1649279.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Effect of gluten-free diet and antibiotics on murine gut microbiota and immune response to tetanus vaccination

    Kihl, Pernille, Krych, Lukasz, Deng, Ling, Hansen, Lars Hestbjerg, Buschard, K., Skov, Søren, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: Plos One. 17, 4, 21 p., e0266719.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Dietary Intervention Accelerates NASH Resolution Depending on Inflammatory Status with Minor Additive Effects on Hepatic Injury by Vitamin E Supplementation

    Klaebel, J. H., Rakipovski, G., Andersen, B., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2020, In: Antioxidants. 9, 9, 808.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Atorvastatin and vitamin e accelerates NASH resolution by dietary intervention in a preclinical guinea pig model

    Klaebel, J. H., Skjødt, M., Skat-Rørdam, Josephine, Rakipovski, G., Ipsen, David Højland, Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 11, 20 p., 2834.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Efficacy of fibroblast growth factor 21 in non-alcoholic fatty liver disease in guinea pigs

    Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Basic & Clinical Pharmacology & Toxicology. 130, 3, p. 385-393

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Differential toxicological response to positively and negatively charged nanoparticles in the rat brain

    Knudsen, K. B., Northeved, H., Ek, P. K., Permin, A., Andresen, T. L., Larsen, S., Wegener, K. M., Lam, H. R. & Lykkesfeldt, Jens, 2014, In: Nanotoxicology. 8, 7, p. 764-774 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats

    Knudsen, K. B., Northeved, H., Gjetting, T., Permin, A., Andresen, T. L., Wegener, K. M., Rye Lam, H. & Lykkesfeldt, Jens, 2014, In: Journal of Nanoparticle Research. 16, 1, 11 p., 2221.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    In vivo toxicity of cationic micelles and liposomes

    Knudsen, K. B., Northeved, H., Kumar Ek, P., Permin, A., Gjetting, T., Andresen, T. L., Larsen, S., Wegener, K. M., Lykkesfeldt, Jens, Jantzen, K., Loft, Steffen, Møller, Peter & Roursgaard, Martin, 25 Feb 2015, In: Nanomedicine: Nanotechnology, Biology and Medicine. 11, 2, p. 467-477 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by MKL2, ternary complex factors, and actin dynamics

    Krawczyk, K. K., Skovsted, Gry Freja, Perisic, L., Dreier, R., Berg, Jais Oliver, Hedin, U., Rippe, C. & Swärd, K., 2018, In: American Journal of Physiology - Cell Physiology. 315, 6, p. C873-C884

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by ternary complex factors and the actin cytoskeleton

    Krawczyk, K. K., Skovsted, Gry Freja, Perisic, L., Rippe, C., Dreier, R., Berg, J. O., Lykkesfeldt, Jens, Hedin, U. & Sward, K., Apr 2018.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  19. Published

    Calcium signaling in coronary artery after reperfusion damage in rat model of acute myocardial infarct

    Kristiansen, S. B., Skovsted, Gry Freja, Sheykhzade, Majid & Edvinsson, L., Sep 2015, In: Acta Physiologica (Print). 215, Supplement, p. 3-4 7.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  20. Published

    Role of pannexin and adenosine triphosphate (ATP) following myocardial ischemia/reperfusion

    Kristiansen, S. B., Skovsted, Gry Freja, Berchtold, L. A., Radziwon-Balicka, A., Dreisig, K., Edvinsson, L., Sheykhzade, Majid & Haanes, Kristian Agmund, 2018, In: Scandinavian Cardiovascular Journal. 52, 6, p. 340-343

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Myocardial Changes in Diabetic and Nondiabetic Nonhuman Primates

    Krog, S., Ludvigsen, Trine Pagh, Nielsen, O. L., Kirk, R. K., Lykkegaard, K., Wulff, E. M., Møller, J. E., Pedersen, H. D. & Olsen, Lisbeth Høier, 2020, In: Veterinary Pathology. 57, 2, p. 332-343 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Have you tried spermine? A rapid and cost-effective method to eliminate dextran sodium sulfate inhibition of PCR and RT-PCR

    Krych, Lukasz, Kot, W., Bendtsen, K. M. B., Hansen, Axel Kornerup, Vogensen, Finn Kvist & Nielsen, Dennis Sandris, 2018, In: Journal of Microbiological Methods. 144, p. 1-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    No effect of melatonin to modify surgical-stress response after major vascular surgery: a randomised placebo-controlled trial

    Kücükakin, B., Wilhelmsen, M., Lykkesfeldt, Jens, Reiter, R. J., Rosenberg, J. & Gögenur, I., 2010, In: European Journal of Vascular and Endovascular Surgery. 40, 4, p. 461-467 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    No effect of melatonin on oxidative stress after laparoscopic cholecystectomy: a randomized placebo-controlled trial

    Kücükakin, B., Klein, M., Lykkesfeldt, Jens, Reiter, R. J., Rosenberg, J. & Gögenür, I., 2010, In: Acta Anaesthesiologica Scandinavica. 54, 9, p. 1121-1127 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Storage-induced increase in biomarkers of oxidative stress and inflammation in red blood cell components

    Kücükakin, B., Kocak, V., Lykkesfeldt, Jens, Nielsen, H. J., Magnussen, K., Rosenberg, Jacob & Gögenür, I., 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 4, p. 299-303 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Symmetric Dimethylarginine in Cats with Hypertrophic Cardiomyopathy and Diabetes Mellitus

    Langhorn, Rebecca, Kieler, Ida Nordang, Koch, Jørgen, Christiansen, L. B. & Jessen, Lisbeth Rem, Jan 2018, In: Journal of Veterinary Internal Medicine. 32, 1, p. 57-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Analytical validation of a conventional cardiac troponin I assay for dogs and cats

    Langhorn, Rebecca, Yrfelt, J. D., Stjernegaard, C. S., Christiansen, L. B., Olsen, Lisbeth Høier & Nielsen, Lise Nikolic, 2019, In: Veterinary Clinical Pathology. p. 36-41

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans: randomised, controlled trials

    Larsen, E. L., Cejvanovic, V., Kjær, L. K., Pedersen, M. T., Popik, S. D., Hansen, L. K., Andersen, Jon Thor Trærup, Solem, Espen Victor Jimenez, Broedbaek, K., Petersen, M., Weimann, A., Henriksen, T., Lykkesfeldt, Jens, Torp-Pedersen, C. & Poulsen, Henrik Enghusen, Aug 2017, In: British Journal of Clinical Pharmacology. 83, 8, p. 1643-1653

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Effects of two- and twelve-weeks sodium-glucose cotransporter 2 inhibition on DNA and RNA oxidation: two randomized, placebo-controlled trials

    Larsen, E. L., Andersen, A., Kjær, L. K., Eickhoff, M. K., Frimodt-Møller, M., Persson, F., Rossing, Peter, Lykkesfeldt, Jens, Knop, Filip Krag, Vilsbøll, Tina, Rungby, Jørgen & Poulsen, Henrik Enghusen, 2023, In: Free Radical Research. 57, 2, p. 140-151

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Gestational Protein Restriction in Wistar Rats; Effect of Taurine Supplementation on Properties of Newborn Skeletal Muscle

    Larsen, L. H., Sandø-Pedersen, S., Ørstrup, Laura Kofoed Hvidsten, Grunnet, N., Quistorff, B. & Mortensen, Ole Hartvig, 2017, Taurine 10. Lee, D-H., Schaffer, S. W., Park, E. & Kim, H. W. (eds.). Springer, Vol. 975. p. 413-433 21 p. (Advances in Experimental Medicine and Biology; No. 975).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  31. Published

    Effect of High Inspiratory Oxygen Fraction on Endothelial Dysfunction in Healthy Volunteers: A Randomized Controlled Cross-over Pilot Study

    Larsen, M. H. H., Ekeløf, S., Kokotovic, D., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Gögenur, I., 2017, In: Anesthesia and Analgesia. 125, 5, p. 1793–1796

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Physiological parameters of endurance horses pre-compared to post-race, correlated with performance: a two race study from Scandinavia

    Larsson, J., Pilborg, P. H., Johansen, M., Christophersen, M. T., Holte, A., Roepstorff, L., Olsen, Lisbeth Høier & Harrison, Adrian Paul, 2013, In: ISRN Veterinary Science. 2013, 12 p., 684353.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    ProANP plasma measurement predicts all-cause mortality in acutely hospitalised patients: a cohort study

    Lauridsen, B. K., Iversen, K., Hunter, I., Bay, M., Kirk, V., Nielsen, O. W., Nielsen, H., Boesgaard, S., Køber, Lars Valeur & Goetze, J. P., 2013, In: B M J Open. 3, 10 p., e003288.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Pasteurization Procedures for Donor Human Milk Affect Body Growth, Intestinal Structure, and Resistance against Bacterial Infections in Preterm Pigs

    Li, Y., Nguyen, Duc Ninh, de Waard, M., Christensen, Lars, Zhou, P., Jiang, Pingping, Sun, Jing, Bojesen, Anders Miki, Lauridsen, C., Lykkesfeldt, Jens, Dalsgaard, T. K., Bering, S. B. & Sangild, Per Torp, Jun 2017, In: Journal of Nutrition. 147, 6, p. 1121-1130

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Regulation of vitamin C homeostasis during deficiency

    Lindblad, M. M., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrients. 5, 8, p. 2860-2879 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Evaluating IL-21 as a Potential Therapeutic Target in Crohn's Disease

    Lindebo Holm, T., Tornehave, D., Søndergaard, H., Kvist, P. H., Sondergaard, B., Hansen, L., Hermit, M. B., Holgersen, Kristine, Vergo , S., Frederiksen , K. S., Haase, C. & Lundsgaard, D., 10 Apr 2018, In: Gastroenterology Research and Practice. 2018, 22 p., 5962624.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Dietary LPS traces influences disease expression of the diet-induced obese mouse

    Lindenberg, F. C. B., Ellekilde, M., Thörn, A. C., Kihl, Pernille, Larsen, C. S., Hansen, Camilla Hartmann Friis, Metzdorff, S. B., Aalbæk, Bent & Hansen, Axel Kornerup, 2019, In: Research in Veterinary Science. 123, p. 195-203 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    An Oligosaccharide Rich Diet Increases Akkermansia spp. Bacteria in the Equine Microbiota

    Lindenberg, F. C., Lützhøft, Ditte Olsen, Krych, Lukasz, Fielden, J., Kot, Witold, Frøkiær, Hanne, van Galen, G., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2021, In: Frontiers in Microbiology. 12, 666039.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. E-pub ahead of print

    Validation of computed tomography as a diagnostic tool in guinea pigs with non-alcoholic fatty liver disease

    Lintrup, K., Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens, Tveden-Nyborg, Pernille & Buelund, Lene Elisabeth, 2024, (E-pub ahead of print) In: Laboratory Animals.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Coronary flow and reactivity, but not arrhythmia vulnerability, are affected by cardioplegia during cardiopulmonary bypass in piglets

    Liuba, P., Johansson, S., Pesonen, E., Odermarsky, M., Hansen, Axel Kornerup, Forslid, A., Aburawi, E. H., Higgins, T., Birck, M. M. & Perez-de-Sa, V., 2013, In: Journal of Cardiothoracic Surgery. 8, 6 p., 157.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Acute Haemarthrosis in the Haemophilia A Rat Generates a Local and Systemic Proinflammatory Response

    Lovgren, K. M., Christensen, K. R., Majewski, W., Ostrup, O., Skov, Søren & Wiinberg, B., Nov 2017, In: Thrombosis and Haemostasis. 117, 11, p. 2092-2104

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    18F-FDG PET/MR-imaging in a Göttingen Minipig model of atherosclerosis: Correlations with histology and quantitative gene expression

    Ludvigsen, T. P., Pedersen, S. F., Vegge, A., Ripa, Rasmus Sejersten, Johannesen, H. H., Hansen, Adam Espe, Löfgren, J., Schumacher-Petersen, Camilla, Kirk, R. K., Pedersen, H. D., Christoffersen, B. Ø., Ørbæk, M., Forman, Julie Lyng, Klausen, T. L., Olsen, Lisbeth Høier & Kjær, Andreas, 2019, In: Atherosclerosis. 285, p. 55-63 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Structural remodeling in cerebral and mesenteric arteries from obese Göttingen minipigs with or without diabetes

    Ludvigsen, Trine Pagh, Olsen, Lisbeth Høier, Pedersen, H. D., Østergaard Christoffersen, B. & Jensen, Lars Jørn, 13 Sep 2018, p. 467P-468P . 2 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  44. Published

    Hyperglycemia-induced transcriptional regulation of ROCK1 and TGM2 expression is involved in small artery remodeling in obese diabetic Göttingen Minipigs

    Ludvigsen, T. P., Olsen, Lisbeth Høier, Pedersen, H. D., Østergaard Christoffersen, B. & Jensen, Lars Jørn, 2019, In: Clinical Science. 133, 24, p. 2499–2516 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Development and Characterization of an Atherosclerotic Minipig Model

    Ludvigsen, Trine Pagh, 2014, Copenhagen University.

    Research output: Book/ReportPh.D. thesisResearch

  46. Published

    Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals

    Ludvigsen, Trine Pagh, Kirk, R. K., Christoffersen, B. Ø., Pedersen, H. D., Martinussen, Torben, Kildegaard, J., Heegaard, P. M. H., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2015, In: Journal of Translational Medicine. 13, 12 p., 312.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Noninvasive assessment of pulse-wave velocity and flow-mediated vasodilation in anesthetized Göttingen minipigs

    Ludvigsen, Trine Pagh, Wiinberg, N., Jensen, C. J., Callesen, A. T., Andersen, R. W., Jørgensen, A. S. H., Christoffersen, B. Ø., Pedersen, H. D., Moesgaard, S. G. & Olsen, Lisbeth Høier, 2014, In: Comparative Medicine. 64, 6, p. 471-477 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Hyperinsulinaemic hypoglycaemia in non-anaesthetized Göttingen minipigs induces a counter-regulatory endocrine response and electrocardiographic changes

    Lyhne, Mille Kronborg, Vegge, A., Povlsen, G. K., Slaaby, R., Kildegaard, J., Pedersen-Bjergaard, Ulrik & Olsen, Lisbeth Høier, 2021, In: Scientific Reports. 11, 11 p., 5983.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Electrocardiography and heart rate variability in Göttingen Minipigs: Impact of diurnal variation, lead placement, repeatability and streptozotocin-induced diabetes

    Lyhne, Mille Kronborg, Debes, Karina Poulsdóttir, Helgogaard, T., Vegge, A., Kildegaard, J., Pedersen-Bjergaard, Ulrik & Olsen, Lisbeth Høier, 2022, In: Journal of Pharmacological and Toxicological Methods. 118, 107221.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Vitamin C pharmacokinetics*

    Lykkesfeldt, Jens, 1 Jan 2020, Vitamin C: New Biochemical and Functional Insights. CRC Press, p. 55-70 16 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  51. Published

    Vitamin C

    Lykkesfeldt, Jens & Carr, A. C., Jan 2024, In: Advances in Nutrition. 15, 1, 100155.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Reply to Hemilä by Lykkesfeldt and Poulsen

    Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2011, In: British Journal of Nutrition. 105, 3, p. 488 1 p.

    Research output: Contribution to journalLetterResearchpeer-review

  53. Published

    Ascorbate and dehydroascorbic acid as biomarkers of oxidative stress: validity of clinical data depends on vacutainer system used

    Lykkesfeldt, Jens, 2012, In: Nutrition Research. 32, 1, p. 66-69 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Is vitamin C supplementation beneficial? lessons learned from randomised controlled trials

    Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2010, In: British Journal of Nutrition. 103, 9, p. 1251-1259 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    On the effect of vitamin C intake on human health: How to (mis)interprete the clinical evidence

    Lykkesfeldt, Jens, 2020, In: Redox Biology. 34, 13 p., 101532.

    Research output: Contribution to journalReviewResearchpeer-review

  56. Published

    The Pharmacokinetics of Vitamin C

    Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 10, 20 p., 2412.

    Research output: Contribution to journalReviewResearchpeer-review

  57. Published

    Vitamin C

    Lykkesfeldt, Jens, Michels, A. J. & Frei, B., 2014, In: Advances in Nutrition. 5, 1, p. 16-18 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Strategies for Using Plagiarism Software in the Screening of Incoming Journal Manuscripts: Recommendations Based on a Recent Literature Survey

    Lykkesfeldt, Jens, Aug 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 2, p. 161-164

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Vitamin C – a scoping review for Nordic Nutrition Recommendations 2023

    Lykkesfeldt, Jens & Carr, A. C., 2023, In: Food and Nutrition Research. 67, 19 p., 10300.

    Research output: Contribution to journalReviewResearchpeer-review

  60. Published

    Vitamin C

    Lykkesfeldt, Jens & Carr, A. C., Jan 2024, In: Advances in nutrition (Bethesda, Md.). 15, 1, p. 100155

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Antibody response to recombinant human coagulation factor VIII in a new rat model of severe hemophilia A

    Löfgren, Karin Maria, Sondergaard, H., Skov, Søren, Weldingh, K. N., Tranholm, M. & Wiinberg, B., Apr 2016, In: Journal of Thrombosis and Haemostasis. 14, 4, p. 747-756

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Joint bleeds increase the inhibitor response to human factor VIII in a rat model of severe haemophilia A

    Löfgren, Karin Maria, Søndergaard, H., Skov, Søren & Wiinberg, B., Sep 2016, In: Haemophilia. 22, 5, p. 772-779 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Non-genetic risk factors in haemophilia A inhibitor management: the danger theory and the use of animal models

    Löfgren, Karin Maria, Søndergaard, H., Skov, Søren & Wiinberg, B., Sep 2016, In: Haemophilia. 22, 5, p. 657-666 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  64. Published

    Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model

    Lützhøft, Ditte Olsen, Sinioja, T., Christoffersen, B., Jakobsen, Rasmus Riemer, Geng, Dawei, Ahmad, H. F. B., Straarup, E. M., Pedersen, K. M., Kot, Witold, Pedersen, H. D., Cirera, Susanna, Hyötyläinen, T., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: BMC Microbiology. 22, 1, 287.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Short communication: Gut microbial colonization of the mouse colon using faecal transfer was equally effective when comparing rectal inoculation and oral inoculation based on 16S rRNA sequencing

    Lützhøft, Ditte Olsen, Sánchez-Alcoholado, L., Tougaard, P., Mentzel, Caroline M. Junker, Kot, Witold, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2019, In: Research in Veterinary Science. 126, p. 227-232 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings

    Madsen, M. F., Kanters, Jørgen K., Pedersen, P. J., Haugaard, M. M., Carstensen, Helena, Olsen, Lisbeth Høier & Buhl, Rikke, 28 Nov 2016, In: BMC Veterinary Research. 12, 10 p., 266.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Changes in heart rate, arrhythmia frequency, and cardiac biomarker values in horses during recovery after a long-distance endurance ride

    Madsen, M. F., Kanters, Jørgen K., Haugaard, M. M., Pedersen, P. J., Carstensen, Helena, Balling, J. D., Olsen, Lisbeth Høier & Buhl, Rikke, 1 May 2016, In: Journal of the American Veterinary Medical Association. 248, 9, p. 1034-1042 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Oxidative stress response after laparoscopic versus conventional sigmoid resection: a randomized, double-blind clinical trial

    Madsen, M. T., Kücükakin, B., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2012, In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques. 22, 3, p. 215-219 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Deregulation of obesity-relevant genes is associated with progression in BMI and the amount of adipose tissue in pigs

    Mentzel, Caroline M. Junker, Cardoso, T. F., Pipper, C. B., Jacobsen, M. J., Jørgensen, Claus Bøttcher, Cirera, Susanna & Fredholm, Merete, 2018, In: Molecular Genetics and Genomics. 293, 1, p. 129–136 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Angiotensin-converting enzyme activity in Cavalier King Charles Spaniels with an ACE gene polymorphism and myxomatous mitral valve disease

    Meurs, K. M., Olsen, Lisbeth Høier, Reimann, Maria Josefine, Keene, B. W., Atkins, C. E., Adin, D., Aona, B., Condit, J., Defrancesco, T., Reina-Doreste, Y., Stern, J. A., Tou, S., Ward, J. & Woodruff, K., 2018, In: Pharmacogenetics and Genomics. 28, 2, p. 37-40 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Animal models in pharmacology and toxicology

    Meyer, O. A., Svendsen, O. & Lykkesfeldt, Jens, 2011, Handbook of laboratory animal science: volume II: Animal models. Hau, J. & J. Schapiro, S. (eds.). 3. ed. ed. CRC Press, Vol. 2. p. 149-184 36 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  72. Published

    The role of vitamin C in epigenetic cancer therapy

    Mikkelsen, Stine Ulrik, Gillberg, Linn, Lykkesfeldt, Jens & Grønbæk, Kirsten, 2021, In: Free Radical Biology and Medicine. 170, p. 179-193 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Matrix metalloproteinases (MMPs), tissue inhibitors of metalloproteinases (TIMPs) and transforming growth factor-β (TGF-β) in advanced canine myxomatous mitral valve disease

    Moesgaard, S. G., Aupperle, H., Rajamäki, M. M., Falk, T., Rasmussen, C. E., Zois, N. E. & Olsen, Lisbeth Høier, 2014, In: Research in Veterinary Science. 97, 3, p. 560-567 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Flow-mediated vasodilation measurements in Cavalier King Charles Spaniels with increasing severity of myxomatous mitral valve disease

    Moesgaard, S. G., Løwert, C. K., Zois, N. E., Teerlink, T., Molin, M., Falk, B. T., Rasmussen, C. E., Fuentes, V. L., Jones, I. D. & Olsen, Lisbeth Høier, 2012, In: Journal of Veterinary Internal Medicine. 26, 1, p. 61-68 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies

    Mortensen, A. & Lykkesfeldt, Jens, 2014, In: Nitric Oxide: Biology and Chemistry. 36, p. 51-57 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  76. Published

    Guinea pig ascorbate status predicts tetrahydrobiopterin plasma concentration and oxidation ratio in vivo

    Mortensen, A., Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrition Research. 33, 10, p. 859-867 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Kinetics of acid-induced degradation of tetra- and dihydrobiopterin in relation to their relevance as biomarkers of endothelial function

    Mortensen, A. & Lykkesfeldt, Jens, 2013, In: Biomarkers. 18, 1, p. 55-62 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Lower Vitamin C Levels Are Associated With Less Improvement in Negative Symptoms in Initially Antipsychotic-Naïve Patients With First-Episode Psychosis

    Myken, A. N., Ebdrup, Bjørn, Sørensen, M. E., Broberg, B. V., Skjerbæk, M. W., Glenthøj, Birte Yding, Lykkesfeldt, Jens & Nielsen, Mette Ødegaard, 2022, In: The international journal of neuropsychopharmacology. 25, 8, p. 613-618 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Positive charge, negative effect: the impact of cationic nanoparticles in the brain

    Møller, Peter & Lykkesfeldt, Jens, Jul 2014, In: Nanomedicine. 9, 10, p. 1441-3 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  80. Published

    Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity

    Nasser, A., Møller, A. T., Hellmund, V., Thorborg, S. S., Jespersgaard, C., Bjerrum, Ole Jannik, Dupontd, E., Nachman, G., Lykkesfeldt, Jens, Jensen, T. S. & Møller, L. B., 2018, In: Pain. 159, 6, p. 1012-1024 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Advances in targeted delivery of small interfering RNA using simple bioconjugates

    Nielsen, C., Kjems, J., Sørensen, K. R., Engelholm, Lars Henning & Behrendt, Niels, 2014, In: Expert Opinion on Drug Delivery. 11, 5, p. 791-822 32 p.

    Research output: Contribution to journalReviewResearchpeer-review

  82. Published

    The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers

    Nielsen, C. F., van Putten, S. M., Lund, I. K., Melander, M. C., Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Reckzeh, K., Christensen, K. R., Ingvarsen, S. Z., Gårdsvoll, Henrik, Jensen, K. E., Hamerlik, P., Engelholm, Lars Henning & Behrendt, Niels, 2017, In: OncoTarget. 8, 27, p. 44605-44624 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    A porcine model of subcutaneous Staphylococcus aureus infection: a pilot study

    Nielsen, O. L., Mellergaard, M., Frees, Dorte, Larsen, M. N., Skov, Søren, Olsen, Lisbeth Høier & Reimann, Maria Josefine, 2022, In: APMIS - Journal of Pathology, Microbiology and Immunology. 130, 7, p. 359-370

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    A porcine subcutaneous Staphylococcus aureus abscess model - a pilot study

    Nielsen, O. L., Larsen, M. N., Frees, Dorte, Pedersen, M. M., Skov, Søren & Olsen, Lisbeth Høier, 2017.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  85. Published

    Weekly ascorbic acid infusion in castration-resistant prostate cancer patients: A single-arm phase II trial

    Nielsen, Torben Kjær, Højgaard, M., Andersen, Jon Thor Trærup, Jørgensen, N. R., Zerahn, B., Kristensen, B., Henriksen, T., Lykkesfeldt, Jens, Mikines, K. J. & Poulsen, Henrik Enghusen, 2017, In: Translational Andrology and Urology. 6, 3, p. 517-528 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Elimination of ascorbic acid after high-dose infusion in prostate cancer patients: a pharmacokinetic evaluation

    Nielsen, Torben Kjær, Højgaard, M., Andersen, J. T. T., Poulsen, Henrik Enghusen, Lykkesfeldt, Jens & Mikines, K. J., 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 4, p. 343-348 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Translational aspects of rectal evoked potentials: a comparative study in rats and humans

    Nissen, T. D., Brock, C., Graversen, C., J. Coen, S., Hultin, L., Aziz, Q., Lykkesfeldt, Jens & Drewes, A. M., 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, p. G119-G128 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published
  89. Published

    Decreased Right Ventricular Systolic Function in Dogs with Myxomatous Mitral Valve Disease

    Olsen, Lisbeth Høier, Reimann, Maria Josefine, Møller, J. E., Häggström, J., Jangdin, S. E., Falk, B. T., Uggla, T. & Zois, N. E., 2013, In: Journal of Veterinary Internal Medicine. 27, 3, p. 628-629 2 p., C6.

    Research output: Contribution to journalConference abstract in journalResearch

  90. Published

    Cardiovascular of Inflammatory Disease Models: In vivo imaging, Pathology and Pharmacology

    Olsen, Lisbeth Høier, Nielsen, O. L., Hunter, I., Falk, B. T., Cremer, Signe Emilie, Ludvigsen, Trine Pagh, Reimann, Maria Josefine, Olsen, H. G., Nielsen, K. M., Laursen, H., Kronborg, S. & Kjempff, C. T., 2014.

    Research output: Contribution to conferencePosterCommunication

  91. Published

    Chronic vitamin C deficiency promotes redox imbalance in the brain but does not alter sodium-dependent vitamin C transporter 2 expression

    Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrients. 6, 5, p. 1809-1822 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Prenatal vitamin C deficiency results in differential levels of oxidative stress during late gestation in foetal guinea pig brains

    Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Redox Biology. 2, p. 361-367 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Advanced electrocardiographic parameters change with severity of mitral regurgitation in Cavalier King Charles Spaniels in sinus rhythm

    Pakkanen, M. S., Petric, A. D., Olsen, Lisbeth Høier, Stepancic, A., Schlegel, T. T., Falk, B. T., Rasmussen, C. E. & Starc, V., 2012, In: Journal of Veterinary Internal Medicine. 26, 1, p. 93-100 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Prolonged effect of a new O-glycoPEGylated FVIII (N8-GP) in a murine saphenous vein bleeding model

    Pastoft, A. E., Ezban, M., Tranholm, M., Lykkesfeldt, Jens & Lauritzen, B., 2013, In: Haemophilia Online. 19, 6, p. 913-919 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate®)

    Pastoft, A. E., Lykkesfeldt, Jens, Ezban, M., Tranholm, M., Whinna, H. C. & Lauritzen, B., 2012, In: Haemophilia. 18, 5, p. 782-788 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs

    Pedersen, Kamilla, Kruhøffer, L. L., Lykkesfeldt, Jens & Kousholt, B. S., 2022, In: Acta Veterinaria Scandinavica. 64, 38.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published
  98. Published

    Optimization of pig models for translation of subcutaneous pharmacokinetics of therapeutic proteins: Liraglutide, insulin aspart and insulin detemir

    Pedersen, K., Gradel, Anna Katrina Jógvansdóttir, Ludvigsen, T. P., Christoffersen, B. Ø., Fuglsang-Damgaard, C. A., Bendtsen, K. M., Madsen, S. H., Manfé, V. & Refsgaard, H. H. F., 2022, In: Translational Research. 239, p. 71-84

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Feasibility of simultaneous PET/MR in diet-induced atherosclerotic minipig: a pilot study for translational imaging

    Pedersen, S. F., Ludvigsen, Trine Pagh, Johannesen, Helle Hjorth, Löfgren, J., Ripa, Rasmus Sejersten, Hansen, Adam Espe, Ettrup, A. J., Christoffersen, B. Ø., Pedersen, H. D., Olsen, Lisbeth Høier, Højgaard, Liselotte & Kjær, Andreas, 2014, In: American Journal of Nuclear Medicine and Molecular Imaging. 4, 5, p. 448-58 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Does Glucagon-like Peptide-1 Ameliorate Oxidative Stress in Diabetes? Evidence Based on Experimental and Clinical Studies

    Petersen, Karen Ekkelund, Rakipovski, G., Raun, K. & Lykkesfeldt, Jens, 2016, In: Current Diabetes Reviews. 12, 4, p. 331-358 28 p.

    Research output: Contribution to journalReviewResearchpeer-review