- Published
CTLA4-Ig prevents development of neutralizing antibody formation after continuous treatment with human FVIII in HA rats
Øvlisen, Gabi Overgaard, Thygesen, P., Weldingh, K. N., Bloem, E., Skov, Søren, Almholt, K., Lövgren, K. M., Ley, C. D. & Holm, T. L., 2022, In: Haemophilia. 28, 4, p. 568-577Research output: Contribution to journal › Journal article › Research › peer-review
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Efficacy of Elimination of Pasteurella pneumotropica from a Mouse Specific Pathogen-Free Barrier Breeding Unit through Treatment with Enrofloxacin
Østergaard, Grete, Arnorsdottir, S. E., Schumacher-Petersen, Camilla, Bundgaard, C. J., Koch, J. & Hau, Jann, 2010, In: JAALAS - Journal of the American Association for Laboratory Animal Science. 49, 5, p. 671-671 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Cross-species reactive monoclonal antibodies against the extracellular domains of the insulin receptor and IGF1 receptor
Ørstrup, Laura Kofoed Hvidsten, Slaaby, R., Rasch, M. G., Rasmussen, N., Lund, S., Brandt, J., Schluckebier, G., Wang, Z., Lützen, A., Pedersen, T. Å., Hvid, H., Hansen, B. F. & Blume, N., 2019, In: Journal of Immunological Methods. 465, p. 20-26 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Towards a Göttingen minipig model of adult onset growth hormone deficiency: evaluation of stereotactic electrocoagulation method
Ørstrup, Laura Kofoed Hvidsten, Tvilling, L., Orlowski, D., Zaer, H., Bjarkam, C. R., von Voss, P., Andersen, P. S., Christoffersen, B., Hedemann Sørensen, J. C., Laursen, T., Thygesen, P., Lykkesfeldt, Jens & Glud, A. N., 2019, In: Heliyon. 5, 11, 8 p., e02892.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Radial and longitudinal strain and strain rate assessed by speckle-tracking echocardiography in dogs with myxomatous mitral valve disease
Zois, N. E., Tidholm, A., Nägga, K. M., Moesgaard, S. G., Rasmussen, C. E., Falk, B. T., Häggström, J., Pedersen, H. D., Åblad, B., Nilsen, H. Y. & Olsen, Lisbeth Høier, 2012, In: Journal of Veterinary Internal Medicine. 26, 6, p. 1309-1319 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Left ventricular twist and circumferential strain in dogs with myxomatous mitral valve disease
Zois, N. E., Olsen, N. T., Moesgaard, S. G., Rasmussen, C. E., Falk, B. T., Häggström, J., Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2013, In: Journal of Veterinary Internal Medicine. 27, 4, p. 875-883 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Left ventricular twist and twist rate in dogs with mitral regurgitation attributable to myxomatous mitral valve disease
Zois, N. E. & Olsen, Lisbeth Høier, Sep 2012. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
Echocardiographic assessment of left ventricular function in mitral regurgitation: is the dog a useful model of man?
Zois, N. E., Pedersen, H. D., Häggström, J. & Olsen, Lisbeth Høier, 2014, In: Cardiovascular Endocrinology. 3, 1, p. 9-14 6 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Natriuretic peptides in cardiometabolic regulation and disease
Zois, N. E., Bartels, E. D., Hunter, I., Kousholt, B. S., Olsen, Lisbeth Høier & Gøtze, J. P., 2014, In: Nature Reviews Cardiology. 11, 7, p. 403-412 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Circulating cytokine concentrations in dogs with different degrees of myxomatous mitral valve disease
Zois, N. E., Moesgaard, S. G., Kjelgaard-Hansen, M., Rasmussen, C. E., Falk, B. T., Fossing, C., Häggström, J., Pedersen, H. D. & Olsen, Lisbeth Høier, 2012, In: Veterinary Journal. 192, 1, p. 106-111 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
Central control of energy balance by amylin and calcitonin receptor agonists and their potential for treatment of metabolic diseases
Zakariassen, Hannah Louise, John, L. M. & Lutz, T. A., 2020, In: Basic & Clinical Pharmacology & Toxicology. 127, 3, p. 163-177Research output: Contribution to journal › Review › Research › peer-review
- Published
Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice
Zakariassen, Hannah Louise, John, L. M., Lykkesfeldt, Jens, Raun, K., Glendorf, T., Schaffer, L., Lundh, S., Secher, A., Lutz, T. A. & Le Foll, C., 2020, In: Neuropharmacology. 167, 107987.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced early life mucosal integrity decreases thymic cell counts and increases local, but not thymic regulatory, T cell recruitment: Gut mucosal integrity breach and thymic T cells
Zakariassen, Hannah Louise, Bendtsen, K. M., Tougaard, P. & Hansen, Axel Kornerup, 2019, In: European Journal of Inflammation. 17, p. 1-16Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of melatonin on endothelial dysfunction in patients after acute coronary syndrome: The MEFACS randomized clinical trial
Zahid, J. A., Isbrand, A., Kleif, J., Schou-Pedersen, A. V., Lykkesfeldt, Jens, Madsen, M. T. & Gögenur, Ismail, 2019, In: Journal of Pineal Research. 67, 3, e12600.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Antioxidant supplementation does not alter endurance training adaptation
Yfanti, C., Åkerström, T., Nielsen, S., Nielsen, A. R., Mounier, R., Mortensen, Ole Hartvig, Lykkesfeldt, Jens, Rose, A. J., Fischer, C. P. & Pedersen, Bente Klarlund, 1 Jul 2010, In: Medicine and Science in Sports and Exercise. 42, 7, p. 1388-95 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of vitamin C and E supplementation on IL-6 in response to training
Yfanti, C., Fischer, C. P., Nielsen, S., Åkerström, T., Nielsen, A. R., Veskoukis, A. S., Kouretas, D., Lykkesfeldt, Jens, Pilegaard, Henriette & Pedersen, Bente Klarlund, 2012, In: Journal of Applied Physiology. 112, 6, p. 990-1000 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of antioxidant supplementation on insulin sensitivity in response to endurance exercise training
Yfanti, C., Nielsen, A. R., Åkerström, T., Nielsen, S., Rose, A. J., Richter, Erik A., Lykkesfeldt, Jens, Fischer, C. P. & Pedersen, Bente Klarlund, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 300, 5, p. E761-E770 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary magnesium deficiency alters gut microbiota and leads to depressive-like behaviour
Winther, G., Jørgensen, B. M. P., Elfving, B., Nielsen, Dennis Sandris, Kihl, Pernille, Lund, S., Sørensen, Dorte Bratbo & Wegener, G., 2015, In: Acta Neuropsychiatrica (Print). 27, 3, p. 168-176 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Remote Ischaemic Preconditioning on Perioperative Endothelial Dysfunction in Non-Cardiac Surgery: A Randomised Clinical Trial
Wahlstrøm, K. L., Hansen, H. F., Kvist, M., Burcharth, Jakob, Lykkesfeldt, Jens, Gögenur, Ismail & Ekeloef, S., 2023, In: Cells. 12, 6, 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quality of life assessment in dogs and cats receiving chemotherapy: a review of current methods
Vøls, Kåre Kryger, Heden, M. A., Kristensen, Annemarie T. & Sandøe, Peter, 2017, In: Veterinary and Comparative Oncology. 15, 3, p. 684–691 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Bleed volume of experimental knee haemarthrosis correlates with the subsequent degree of haemophilic arthropathy
Vøls, Kåre Kryger, Kjelgaard-Hansen, M., Ley, C. D., Hansen, Axel Kornerup & Petersen, M., 2019, In: Haemophilia. 25, 2, p. 324-333 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Initial joint bleed volume in a delayed on-demand treatment setup correlates with subsequent synovial changes in hemophilic mice
Vøls, Kåre Kryger, Kjelgaard-Hansen, M., Ley, C. D., Hansen, Axel Kornerup & Petersen, M., 2020, In: Animal models and experimental medicine. 3, 2, p. 160-168 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo fluorescence molecular tomography of induced haemarthrosis in haemophilic mice: link between bleeding characteristics and development of bone pathology
Vøls, Kåre Kryger, Kjelgaard-Hansen, M., Ley, C. D., Hansen, Axel Kornerup & Petersen, M., 14 Apr 2020, In: BMC Musculoskeletal Disorders. 21, 1, 10 p., 241.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro cell cultures of Brunner's glands from male mouse to study GLP-1 receptor function
Voetmann, Louise Marie, Underwood, C. R., Rolin, B., Hansen, Axel Kornerup, Kirk, R. K., Pyke, C., Knudsen, L. B. & Frederiksen, K. S., 2022, In: American journal of physiology. Cell physiology. 322, 6, p. C1260-C1269Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intestinal permeability marker FITC-dextran 4kDa should be dosed according to lean body mass in obese mice
Voetmann, Louise Marie, Rolin, B., Kirk, R. K., Pyke, C. & Hansen, Axel Kornerup, 2023, In: Nutrition and Diabetes. 13, 1.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A cafeteria diet alters the decision making strategy and metabolic markers in Sprague-Dawley male rats
Virtuoso, Alessandro, Forkman, Björn, Sarruf, D. A., Tveden-Nyborg, Pernille & Sørensen, Dorte Bratbo, 2018, In: Applied Animal Behaviour Science. 199, p. 35-44 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A long‐term energy‐rich diet increases prefrontal bdnf in sprague‐dawley rats
Virtuoso, Alessandro, Tveden-Nyborg, Pernille, Schou‐pedersen, A. M. V., Lykkesfeldt, Jens, Müller, H. K., Elfving, B. & Sørensen, Dorte Bratbo, 2022, In: Nutrients. 14, 1, 126.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nephrectomized and hepatectomized animal models as tools in preclinical pharmacokinetics
Vestergaard, Bill, Agersø, H. & Lykkesfeldt, Jens, 2013, In: Basic & Clinical Pharmacology & Toxicology Online. 113, 2, p. 75-86 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colonic lesions, cytokine profiles, and gut microbiota in plasminogen-deficient mice
Vestergaard, Bill, Krych, Lukasz, Lund, L. R., Jørgensen, B. M. P., Hansen, Lars Hestbjerg, Jensen, Henrik Elvang, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2015, In: Comparative Medicine. 65, 5, p. 382-397 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The kidneys play a central role in the clearance of rhGH in rats
Vestergaard, Bill, Thygesen, P., Kreilgaard, M., Fels, J. J., Lykkesfeldt, Jens & Agerso, H., 30 Apr 2016, In: European Journal of Pharmaceutical Sciences. 86, p. 29-33Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The kidneys play an important role in the clearance of rFVIIa in rats
Vestergaard, Bill, Appa, R. S., Lykkesfeldt, Jens & Agersø, H., 2014, In: Thrombosis Research. 133, 6, p. 1124-1129 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Establishment and use of surgical rat models for assessment of organ specific in vivo clearance
Vestergaard, Bill, Jun 2016, In: Danish Medical Journal. 63, 6, 17 p., B5247.Research output: Contribution to journal › Review › Research › peer-review
- Published
Human and equine cardiovascular endocrinology: beware to compare
Vekens, N. V. D., Hunter, I., Goetze, Jens P. , Decloedt, A., Clercq, D. D. & Loon, G. V., 2013, In: Cardiovascular Endocrinology. 2, 4, p. 67-76 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies
Tveden-Nyborg, Pernille, Bergmann, T. K. & Lykkesfeldt, Jens, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 233-235 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
BCPT policy for experimental and clinical studies
Tveden-Nyborg, Pernille, Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, Jens, 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 4-8Research output: Contribution to journal › Review › Research › peer-review
- Published
Vitaminer til hjernen
Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Aktuel Naturvidenskab. 2016, 4, p. 8-11 4 p.Research output: Contribution to journal › Journal article › Research
- Published
BCPT 2023 policy for experimental and clinical studies
Tveden-Nyborg, Pernille, Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, Jens, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 4, p. 391-396Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does vitamin C deficiency increase lifestyle-associated vascular disease progression? evidence based on experimental and clinical studies
Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Antioxidants & Redox Signaling. 19, 17, p. 2084-2104 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maternal vitamin C deficiency during pregnancy persistently impairs hippocampal neurogenesis in offspring of guinea pigs
Tveden-Nyborg, Pernille, Vogt, L., Schjoldager, J. G., Jeannet, N., Andersen, S. H., Paidi, M. D., Christen, S. & Lykkesfeldt, Jens, 2012, In: P L o S One. 7, 10, 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diet-induced dyslipidemia leads to nonalcoholic fatty liver disease and oxidative stress in guinea pigs
Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland, Thiessen, T. S., Feldmann, L. D. B., Lindblad, M. M., Jensen, Henrik Elvang & Lykkesfeldt, Jens, 1 Feb 2016, In: Translational Research. 168, p. 146-160 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic vitamin C deficiency does not accelerate oxidative stress in ageing brains of guinea pigs
Tveden-Nyborg, Pernille, Andersen, S. H., Miyashita, N., Moos, T., Poulsen, Henrik Enghusen & Lykkesfeldt, Jens, 2012, In: Basic & Clinical Pharmacology & Toxicology Online. 110, 6, p. 524-529 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic dyslipidemia induces fatty liver disease in Guinea pigs
Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland & Lykkesfeldt, Jens, Jul 2015, In: Atherosclerosis. 241, 1, p. e119-e120 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
High-fat feeding induces mobilization of vitamin C in obese prone rats
Tranberg, B., Hellgren, L. I., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2018, In: Research in Veterinary Science. 119, p. 167-169 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TL1A regulates adipose-resident innate lymphoid immune responses and enables diet-induced obesity in mice
Tougaard, P., Martinsen, L. O., Lützhøft, Ditte Olsen, Jensen, Henrik Elvang, Flethøj, M., Vandenabeele, P., Pedersen, Anders Elm, Skov, Søren, Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2020, In: International journal of obesity (2005). 44, p. 1062–1074Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spontaneous bleeds in the elbows of F8-/- rats cause development of blood-induced joint disease closely resembling human hemophilic arthropathy
Thyme, A. P., Vøls, Kåre Kryger, Christensen, K. R., Löfgren, Karin Maria, Wiinberg, B., Kvist, P. H., Kjelgaard-Hansen, M., Roepstorff, K., Nielsen, Lise Nikolic & Tranholm, M., 2016.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Effect of insulin on natriuretic peptide gene expression in porcine heart
Terzic, D., Zois, N. E., Hunter, I., Christoffersen, Christina, Plomgaard, Peter Stendahl, Olsen, Lisbeth Høier, Jørgensen, Stine Ringholm, Pilegaard, Henriette & Goetze, Jens P. , 2020, In: Peptides. 131, 10 p., 170370.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo vitamin C deficiency in guinea pigs increases ascorbate transporters in liver but not kidney and brain
Søgaard, D., Lindblad, M. M., Paidi, M. D., Andersen, S. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrition Research. 34, 7, p. 639-645 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Third-stage nematode larvae of Contracaecum osculatum from Baltic cod (Gadus morhua) elicit eosinophilic granulomatous reactions when penetrating the stomach mucosa of pigs
Strøm, S. B., Haarder, S., Korbut, R., Mejer, H., Thamsborg, Stig Milan, Kania, Per & Buchmann, Kurt, 2015, In: Parasitology Research. 114, 3, p. 1217-1220 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vivo effect of rFVIII and rFVIIa in hemophilia A rats evaluated by the Tail Vein Transection Bleeding Model
Stagaard, Rikke, Øvlisen, Gabi Overgaard, Klæbel, J. H., Danielsen, D., Lund, A., Elm, T. & Ley, C. D., 2023, In: Journal of Thrombosis and Haemostasis. 21, 5, p. 1189-1199 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Absence of functional compensation between coagulation factor VIII and plasminogen in double-knockout mice
Stagaard, R., Ley, C. D., Almholt, K., Olsen, Lisbeth Høier, Knudsen, T. & Flick, M. J., 2018, In: Blood advances. 2, 22, p. 3126-3136 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Abrogating fibrinolysis does not improve bleeding or rFVIIa/rFVIII treatment in a non-mucosal venous injury model in haemophilic rodents
Stagaard, R., Flick, M. J., Bojko, B., Goryński, K., Goryńska, P. Z., Ley, C. D., Olsen, Lisbeth Høier & Knudsen, T., 2018, In: Journal of Thrombosis and Haemostasis. 16, 7, p. 1369-1382 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced Mechanical Stretch Induces Enhanced Endothelin B Receptor-mediated Contractility via Activation of Focal Adhesion Kinase and Extra Cellular-regulated Kinase 1/2 in Cerebral Arteries from Rat
Spray, S., Rasmussen, M. N. P., Skovsted, Gry Freja, Warfvinge, K., Sheykhzade, Majid & Edvinsson, L., Jun 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 1, p. 68-77 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of the sodium-glucose cotransporter-2 inhibitor dapagliflozinon platelet aggregation response in Cavalier King Charles Spanielswith and without cardiac disease
Speitzer, A., Øgelund, E., Reimann, Maria Josefine, Møller, J. E., Skovsted, G. F., Lyhne, Mille Kronborg, Verma, S., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2022, In: Journal of Veterinary Internal Medicine. 36, 6, p. 2473 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Cardiac natriuretic peptide gene expression and plasma concentrations during the first 72 hours of life in piglets
Smith, J., Christoffersen, Christina, Nørgaard, L. M., Olsen, Lisbeth Høier, Vejlstrup, N. G., Andersen, C. B. & Gøtze, J. P., 2013, In: Endocrinology. 154, 5, p. 1864-1872 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discordant porcine cardiac natriuretic peptide gene expression and plasma concentrations during the first 72 h of life
Smith, J., Christoffersen, C., Nørgaard, L. M., Olsen, Lisbeth Høier, Vejlstrup, N. G., Andersen, C. B. & Goetze, J. P., 2012, In: Regulatory Peptides. 177, Supplement, p. S33 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Vitamin C deficiency reduces muscarinic receptor coronary artery vasoconstriction and plasma tetrahydrobiopterin concentration in guinea pigs
Skovsted, Gry Freja, Tveden-Nyborg, Pernille, Lindblad, M. M., Hansen, S. N. & Lykkesfeldt, Jens, 2017, In: Nutrients. 9, 7, 14 p., 691.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expression of endothelin type B receptors in uterine artery smooth muscle cells from pregnant Guinea pigs
Skovsted, Gry Freja, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2019, In: Placenta. 77, p. 8-15 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of S1P-receptor and Rho-kinase in myogenic tone in mesenteric and cerebral arteries of young vs. middle-aged mice
Skovsted, Gry Freja, Aupetit, A., Björling , K., Haanes, K. A., Syberg, S., Jørgensen, N. R., Freude, Kristine, Pearson, J. T. & Jensen, Lars Jørn, 2023, In: Acta Physiologica. 239, S728, e14042.Research output: Contribution to journal › Conference abstract in journal › Communication
- Published
Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ETB receptors via the protein kinase MEK-ERK1/2 signaling pathway in rat
Skovsted, Gry Freja, Kruse, L. S., Berchtold, L. A., Grell, A., Warfvinge, K. & Edvinsson, L., 1 Mar 2017, In: PLOS ONE. 12, 3, 18 p., e0174119.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin C Deficiency Exacerbates Dysfunction of Atherosclerotic Coronary Arteries in Guinea Pigs Fed a High-Fat Diet
Skovsted, Gry Freja, Skat-Rørdam, Josephine, Frøkiær, A. P., Jensen, Henrik Elvang, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2022, In: Antioxidants. 11, 11, 2226.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Holder C-vitamin dine blodkar sunde?
Skovsted, Gry Freja, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2018Research output: Other contribution › Net publication - Internet publication › Communication
- Published
Endothelin-1 and endothelin-3 regulate endothelin receptor expression in rat coronary arteries
Skovsted, Gry Freja, Kilic, S. & Edvinsson, L., 2015, In: Basic & Clinical Pharmacology & Toxicology Online. 117, 5, p. 297-305 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study
Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ascorbate deficiency increases progression of shigellosis in guinea pigs and mice infection models
Skerniskyte, J., Mulet, C., André, A. C., Anderson, M. C., Injarabian, L., Buck, A., Prade, V. M., Sansonetti, P. J., Reibel-Foisset, S., Walch, A. K., Lebel, M., Lykkesfeldt, Jens & Marteyn, B. S., 2023, In: Gut Microbes. 15, 2, 18 p., 2271597.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of dietary components on glucose intolerance and non‐alcoholic steatohepatitis
Skat-Rørdam, Josephine, Ipsen, David Højland, Hardam, P. D., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Nutrients. 13, 8, 2523.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modelling nonalcoholic steatohepatitis in vivo—a close transcriptomic similarity supports the guinea pig disease model
Skat-Rørdam, Josephine, Ipsen, David Højland, Seemann, Ernst Stefan, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, Sep 2021, In: Biomedicines. 9, 9, 1198.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modelling Nonalcoholic Steatohepatitis In Vivo—A Close Transcriptomic Similarity Supports the Guinea Pig Disease Model
Skat-Rørdam, Josephine, Ipsen, David Højland, Seemann, Ernst Stefan, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 9, 18 p., 1198.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin C deficiency may delay diet-induced NASH regression in the guinea pig
Skat-Rørdam, Josephine, Pedersen, Kamilla, Skovsted, Gry Freja, Gregersen, I., Vangsgaard, S., Ipsen, David Højland, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Antioxidants. 11, 1, 69.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A role of peroxisome proliferator-activated receptor gamma in non-alcoholic fatty liver disease
Skat-Rørdam, Josephine, Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, May 2019, In: Basic & Clinical Pharmacology & Toxicology. 124, 5, p. 528-537Research output: Contribution to journal › Review › Research › peer-review
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Welcome to Basic & Clinical Pharmacology & Toxicology 2024
Simonsen, U. & Lykkesfeldt, Jens, 2024, In: Basic and Clinical Pharmacology and Toxicology. 134, 1, p. 126-128Research output: Contribution to journal › Journal article › Research
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Charting a new course: A vision for the future as editors-in-chief
Simonsen, U. & Lykkesfeldt, Jens, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 4, p. 390 1 p.Research output: Contribution to journal › Editorial › Research
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IL-33 promotes GATA-3 polarization of gut-derived T cells in experimental and ulcerative colitis
Seidelin, Jakob Benedict, Coskun, M., Kvist, P. H., Holm, T. L., Holgersen, Kristine & Nielsen, Ole Haagen, Feb 2015, In: Journal of Gastroenterology. 50, 2, p. 180-190 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Experimental non-alcoholic steatohepatitis in Göttingen Minipigs: Consequences of high fat-fructose-cholesterol diet and diabetes
Schumacher-Petersen, Camilla, Christoffersen, B. O., Kirk, R. K., Ludvigsen, T. P., Zois, N. E., Pedersen, H. D., Vyberg, M. & Olsen, Lisbeth Høier, 2019, In: Journal of Translational Medicine. 17, 1, 110.Research output: Contribution to journal › Journal article › Research › peer-review
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An improved method for lifting and transporting anesthetized pigs within an animal facility
Schumacher-Petersen, Camilla, Hammelev, Karsten Pharao & Flescher, Jens, Jul 2014, In: Lab Animal. 43, 7, p. 237-41 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Simultaneous quantification of monoamine neurotransmitters and their biogenic metabolites intracellularly and extracellularly in primary neuronal cell cultures and in sub-regions of guinea pig brain
Schou-Pedersen, A. M. V., Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 15 Aug 2016, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1028, p. 222-230 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of Three Sample Preparation Procedures for the Quantification of L-Arginine, Asymmetric Dimethylarginine, and Symmetric Dimethylarginine in Human Plasma Using HPLC-FLD
Schou-Pedersen, A. M. V. & Lykkesfeldt, Jens, 1 Feb 2018, In: Journal of Analytical Methods in Chemistry. 2018, 7 p., 6148515.Research output: Contribution to journal › Journal article › Research › peer-review
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Determination of reduced and oxidized coenzyme Q10 in canine plasma and heart tissue by HPLC-ECD: Comparison with LC-MS/MS quantification
Schou-Pedersen, A. M. V., Schemeth, D. & Lykkesfeldt, Jens, 2019, In: Antioxidants. 8, 8, 253.Research output: Contribution to journal › Journal article › Research › peer-review
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Maternal vitamin C deficiency during pregnancy results in transient fetal and placental growth retardation in guinea pigs: [Plus] erratum
Schjoldager, J. G., Paidi, M. D., Lindblad, M. M., Birck, M. M., Kjærgaard, A. B., Dantzer, V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2015, In: European Journal of Nutrition. 54, 4, p. 667-676 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prolonged maternal vitamin C deficiency overrides preferential fetal ascorbate transport but does not influence perinatal survival in guinea pigs
Schjoldager, J. G., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: British Journal of Nutrition. 110, 9, p. 1573-1579 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Modulating the gut microbiota improves glucose tolerance, lipoprotein profile and atherosclerotic plaque development in ApoE-deficient mice
Rune, Ida, Rolin, B., Larsen, C. S., Nielsen, Dennis Sandris, Kanter, J. E., Bornfeldt, K. E., Lykkesfeldt, Jens, Buschard, K., Kirk, R. K., Christoffersen, B., Fels, J. J., Josefsen, K., Kihl, Pernille & Hansen, Axel Kornerup, 2016, In: P L o S One. 11, 1, 16 p., e0146439.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice
Rune, Ida, Hansen, Axel Kornerup, Ellekilde, M., Nielsen, Dennis Sandris & Hansen, C., Nov 2011. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
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Ampicillin-improved glucose tolerance in diet-induced obese C57BL/6NTac mice is age dependent
Rune, Ida, Hansen, Camilla Hartmann Friis, Ellekilde, M., Nielsen, Dennis Sandris, Skovgaard, K., Rolin, B. C., Lykkesfeldt, Jens, Josefsen, K., Christensen, B. T., Kihl, Pernille & Hansen, Axel Kornerup, 2013, In: Experimental Diabetes Research. 2013, 13 p., 319321.Research output: Contribution to journal › Journal article › Research › peer-review
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Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics
Rune, Ida, Rolin, B., Lykkesfeldt, Jens, Nielsen, Dennis Sandris, Krych, Lukasz, Kanter, J. E., Bornfeldt, K. E., Kihl, Pernille, Buschard, K., Josefsen, K., Fels, J. J., Mortensen, A., Christoffersen, B., Kirk, R. K. & Hansen, Axel Kornerup, 2018, In: Scientific Reports. 8, 1, 12 p., 5416.Research output: Contribution to journal › Journal article › Research › peer-review
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In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines
Roursgaard, Martin, Knudsen, K. B., Northeved, H., Persson, M., Christensen, T., Kumar, P. E. K., Permin, A., Andresen, T. L., Gjetting, T., Lykkesfeldt, Jens, Vesterdal, L. K., Loft, Steffen & Møller, Peter, Oct 2016, In: Toxicology in Vitro. 36, p. 164-171 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Microdialysis as a tool for drug quantification in the bronchioles of anaesthetized pigs
Rottbøll, Lisa Amanda Holm & Friis, C., 2014, In: Basic & Clinical Pharmacology & Toxicology Online. 114, 3, p. 226-232 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Intrabronchial microdialysis: effects of probe localization on tissue trauma and drug penetration into the pulmonary epithelial lining fluid
Rottbøll, Lisa Amanda Holm, Skovgaard, K., Barington, Kristiane, Jensen, Henrik Elvang & Friis, C., 2015, In: Basic & Clinical Pharmacology & Toxicology. 117, 4, p. 242-250 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Penetration of antimicrobials to pulmonary epithelial lining fluid and muscle and impact of drug physicochemical properties determined by microdialysis
Rottbøll, Lisa Amanda Holm & Friis, C., 2016, In: Journal of Pharmacological and Toxicological Methods. 78, p. 58-65 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Antimicrobial drug penetration into the pulmonary epithelial lining fluid and muscle measured by microdialysis in anesthetized pigs
Rottbøll, Lisa Amanda Holm & Friis, C., Jul 2015, In: Journal of Veterinary Pharmacology and Therapeutics. 38, S1, p. 89 1 p., 1.12.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Generation of eight hiPSCs lines from two pathogenic variants in CACNA1A using the CRISPR-Cas9 gene editing technology
Rivera-Sánchez, P., Søndergaard, L., Wathikthinnakon, Methi, B. D. Magnusson, H., Frederiksen, Henriette Reventlow S, Aabæk Hammer, F., Taleb, R., Christian Cassidy, C., Tranholm Bruun, M., Tümer, Asuman Zeynep, Holst, B., Brasch-Andersen, C., Møller, R., Freude, Kristine & Chandrasekaran, Abinaya, 2023, In: Stem Cell Research. 71, 103193.Research output: Contribution to journal › Journal article › Research › peer-review
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R-R interval variations influence the degree of mitral regurgitation in dogs with myxomatous mitral valve disease
Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: The Veterinary Journal. 199, 3, p. 348-354 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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R-R interval variations influence the degree of mitral regurgitation in dogs with myxomatous mitral valve disease
Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2013.Research output: Contribution to conference › Poster › Research
- Published
Biopterin status in dogs with myxomatous mitral valve disease is associated with disease severity and cardiovascular risk factors
Reimann, Maria Josefine, Häggström, J., Mortensen, A., Lykkesfeldt, Jens, Møller, J. E., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1520-1526 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Myxømatøs mitralklapsygdom hos hund: Medicinsk behandling
Reimann, Maria Josefine, Christiansen, L. B., Falk, B. T. & Olsen, Lisbeth Høier, 2019, In: Dansk Veterinaertidsskrift. 2019, 11, p. 38-43Research output: Contribution to journal › Journal article › Research › peer-review
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Influence of R-R interval variations on the degree of mitral regurgitation in dogs with myxomatous mitral valve disease
Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2013, In: Journal of Veterinary Internal Medicine. 27, 3, p. 636-637 2 p., C-30.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Myxømatøs mitralklapsygdom hos hund: Metoder til diagnostik af behandlingskrævende sygdomsstadier
Reimann, Maria Josefine, Christiansen, L. B., Falk, T. & Olsen, Lisbeth Høier, 2019, In: Dansk Veterinaertidsskrift. 2019, 9, p. 28-32Research output: Contribution to journal › Review › Research › peer-review
- Published
No impact of polymorphism in the phosphodiesterase 5A gene in Cavalier King Charles Spaniels on pimobendan-induced inhibition of platelet aggregation response
Reimann, Maria Josefine, Faisst, D. N., Knold, M., Meurs, K. M., Stern, J. A., Cremer, Signe Emilie, Møller, J. E., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2023, In: Journal of Veterinary Internal Medicine. 37, 6, p. 1947-2660Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitral valve transcriptome analysis in thirty-four age-matched Cavalier King Charles Spaniels with or without congestive heart failure caused by myxomatous mitral valve disease
Reimann, Maria Josefine, Cremer, Signe Emilie, Christiansen, L., Ibragimov, Emil, Gao, Fei, Cirera, Susanna, Fredholm, Merete, Olsen, Lisbeth Høier & Karlskov-Mortensen, Peter, 2024, In: Mammalian Genome. 35, 1, p. 77-89 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
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Increased systemic oxidatively generated DNA and RNA damage in schizophrenia
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Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
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Novel traceable CRISPR-Cas9 engineered human embryonic stem cell line (E1C3 + hSEAP + 2xKO + pCD47), has potential to evade immune detection in pigs
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Vitamin C
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