Lifepharm

  1. Published

    The potential of human milk oligosaccharides to impact the microbiota-gut-brain axis through modulation of the gut microbiota

    Al-Khafaji, A. H., Jepsen, Stine Dam, Christensen, K. R. & Vigsnæs, L. K., 2020, In: Journal of Functional Foods. 74, 104176.

    Research output: Contribution to journalReviewResearchpeer-review

  2. Published

    Circadian Variation in the Response to Experimental Endotoxemia and Modulatory Effects of Exogenous Melatonin

    Alamili, M., Klein, M., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2013, In: Chronobiology International. 30, 9, p. 1174-1180 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Effect of melatonin on human nighttime endotoxaemia: randomized, double-blinded, cross-over study

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, 6, p. 1057-1063 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Melatonin suppresses markers of inflammation and oxidative damage in a human daytime endotoxemia model

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: Journal of Critical Care. 29, 1, p. 184.e9-184.e13 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Pronounced inflammatory response to endotoxaemia during nighttime: a randomised cross-over trial

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, I., 2014, In: PloS one. 9, 1, 7 p., e87413.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Thick methacrylate sections devoid of lost caps simplify stereological quantifications based on the optical fractionator design

    Andersen, S. H., Lykkesfeldt, Jens & Larsen, J. O., 15 Sep 2015, In: Anatomical Record. 298, 12, p. 2141-2150 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Distribution of vitamin C is tissue specific with early saturation of the brain and adrenal glands following differential oral dose regimens in guinea pigs

    Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2015, In: British Journal of Nutrition. 113, 10, p. 1539-1549 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Vitamin C and its role in brain development and cognition

    Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2012, Nutrition and mental performance: a develomental perspective. Riby, L., Smith, M. & Foster, J. (eds.). Palgrave Macmillan, p. 29-52 24 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  9. Published

    Neonatal Vitamin C Deficiency and Impaired Brain Development: A Dose-response Study

    Andersen, S. H., 2014, Copenhagen University.

    Research output: Book/ReportPh.D. thesisResearch

  10. Published

    Insulin Treatment Attenuates Small Nerve Fiber Damage in Rat Model of Type 2 Diabetes

    Andreasen, L. J., Kirk, R. K., Fledelius, C., Yorek, M. A., Lykkesfeldt, Jens & Akerstrom, T., 2020, In: Journal of Diabetes Research. 2020, 13 p., 9626398.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Dietary normalization from a fat, fructose and cholesterol-rich diet to chow limits the amount of myocardial collagen in a Göttingen Minipig model of obesity

    Andreasen, L. J., Krog, S., Ludvigsen, T. P., Nielsen, O. L., Møller, J. E., Christoffersen, B. Ø., Pedersen, H. D. & Olsen, Lisbeth Høier, 2018, In: Nutrition and Metabolism. 15, 64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Anti-RANKL treatment inhibits erosive joint destruction and lowers inflammation but has no effect on bone formation in the delayed-type hypersensitivity arthritis (DTHA) model

    Atkinson, S. M., Bleil, J., Maier, R., Kuehl, A. A., Thorn, M., Serikawa, K., Fox, B., Kruse, K., Haase, C., Skov, Søren, Nansen, A. & Syrbe, U., 23 Jan 2016, In: Arthritis Research & Therapy. 18, 12 p., 28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Depletion of regulatory T cells leads to an exacerbation of delayedtype hypersensitivity arthritis in C57BL/6 mice that can be counteracted by IL-17 blockade

    Atkinson, S. M., Hoffmann, U., Bach, E., Danneskiold-Samsøe, Niels Banhos, Kristiansen, Karsten, Serikawa, K., Fox, B., Kruse, K., Haase, C., Skov, Søren & Nansen, A., 2016, In: Disease Models & Mechanisms. 9, p. 427-440 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Treatment with anti-C5aR mAb leads to early-onset clinical and mechanistic effects in the murine delayed-type hypersensitivity arthritis model

    Atkinson, S. M., Nansen, A., Usher, P. A., Sondergaard, B., Mackay, C. R., Friedrichsen, B., Chang, C., Tang, R., Skov, Søren, Haase, C. & Hornum, L., Nov 2015, In: Autoimmunity. 48, 7, p. 460-470 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Inflammation and bone remodeling in the delayed-type hypersensitivity (DTH) arthritis model

    Atkinson, S. M., Thorn, M., Autzen Usher, P., Fox, B., Serikawa, K., Biswas, S., Haase, C., Skov, Søren & Nansen, A., 2013, In: Scandinavian Journal of Immunology. 77, 4, p. 304

    Research output: Contribution to journalConference abstract in journalResearch

  16. Published

    The genetic consequences of dog breed formation - Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels: [+ correction]

    Axelsson, E., Ljungvall, I., Bhoumik, P., Conn, L. B., Muren, E., Ohlsson, Å., Olsen, L. H., Engdahl, K., Hagman, R., Hanson, J., Kryvokhyzha, D., Pettersson, M., Grenet, O., Moggs, J., Del Rio-Espinola, A., Epe, C., Taillon, B., Tawari, N., Mane, S., Hawkins, T. & 4 others, Hedhammar, Å., Gruet, P., Häggström, J. & Lindblad-Toh, K., 2021, In: PLOS Genetics. 17, 9, 34 p., e1009726.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    An Early Life Mucosal Insult Temporarily Decreases Acute Oxazolone-Induced Inflammation in Mice

    Bendtsen, K. M., Tougaard, P. & Hansen, Axel Kornerup, 2018, In: Inflammation. 41, 4, p. 1437-1447 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Effect of early-life gut mucosal compromise on disease progression in NOD mice

    Bendtsen, K. M., Hansen, Camilla Hartmann Friis, Krych, Lukasz, Buschard, K., Farlov, H. & Hansen, Axel Kornerup, 2017, In: Comparative Medicine. 67, 5, p. 388-399 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    The influence of the young microbiome on inflammatory diseases - lessons from animal studies

    Bendtsen, K. M. B., Fisker, L., Hansen, Axel Kornerup, Hansen, Camilla Hartmann Friis & Nielsen, Dennis Sandris, 2015, In: Birth Defects Research. Part C: Embryo Today Reviews (Print). 105, 4, p. 278-295 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  20. Published

    Gut microbiota composition is correlated to grid floor induced stress and behavior in the BALB/c mouse

    Bendtsen, K. M. B., Krych, Lukasz, Sørensen, Dorte Bratbo, Pang, W., Nielsen, Dennis Sandris, Josefsen, K., Hansen, Lars Hestbjerg, Sørensen, Søren Johannes & Hansen, Axel Kornerup, 2012, In: P L o S One. 7, 10, 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Immunological effects of reduced mucosal integrity in the early life of BALB/c mice

    Bendtsen, K. M. B., Hansen, Camilla Hartmann Friis, Krych, Lukasz, Skovgaard, K., Kot, W. P., Vogensen, Finn Kvist & Hansen, Axel Kornerup, 2017, In: PLOS ONE. 12, 5, 20 p., 0176662.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    [68Ga]Ga-NODAGA-E[(cRGDyK)]2 Angiogenesis PET/MR in a Porcine Model of Chronic Myocardial Infarction

    Bentsen, Simon, Clemmensen, Andreas Høeg, Loft, Mathias Hougaard, Flethøj, M., Debes, Karina Poulsdóttir, Ludvigsen, Trine Pagh, Larsen, C. B., Kirchhoff, J., Olsen, Lisbeth Høier, Møller, J. E., Andersen, Thomas Lund, Johannesen, Helle Hjorth, Jespersen, Thomas & Kjær, Andreas, 2021, In: Diagnostics. 11, 10, 1807.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Non-terminal blood sampling techniques in Guinea pigs

    Birck, M. M., Tveden-Nyborg, Pernille, Lindblad, M. M. & Lykkesfeldt, Jens, 2014, In: Journal of Visualized Experiments. 92, e51982.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Endothelial cell death and intimal foam cell accumulation in the coronary artery of infected hypercholesterolemic minipigs

    Birck, M. M., Saraste, A., Hyttel, P., Odermarsky, M., Liuba, P., Saukko, P., Hansen, Axel Kornerup & Pesonen, E., 2013, In: Journal of Cardiovascular Translational Research. 6, 4, p. 579-587 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Laparoscopic Roux-en-Y gastric bypass in super obese Göttingen minipigs

    Birck, M. M., Vegge, A., Støckel, M., Gögenur, Ismail, Thymann, Thomas, Hammelev, Karsten Pharao, Sangild, Per Torp, Hansen, Axel Kornerup, Raun, K., von Voss, P. & Eriksen, Thomas, 2013, In: American Journal of Translational Research. 5, 6, p. 643-653 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Evaluation of the breeding program aiming at reducing the prevalence of myxomatous mitral valve disease in Cavalier King Charles Spaniels in Denmark

    Birkegaard , A. C., Reimann, Maria Josefine, Häggström, J., Martinussen, Torben, Pedersen , H. D. & Olsen, Lisbeth Høier, 2013, American College of Veterinary Internal Medicine, Congress Proceedings. Sellon, R. K. & McClure, J. T. (eds.). Lakewood, p. 172 1 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  27. Published

    Breeding Restrictions Decrease the Prevalence of Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels over an 8-to 10-Year Period

    Birkegård, A. C., Reimann, Maria Josefine, Martinussen, Torben, Haggstrom, J., Pedersen, H. D. & Olsen, Lisbeth Høier, 2016, In: Journal of Veterinary Internal Medicine. 30, 1, p. 63-68 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Liraglutide treatment improves endothelial function in the Ldlr-/- mouse model of atherosclerosis, and affects genes involved in vascular remodelling and inflammation

    Bjørnholm, K. D., Skovsted, Gry Freja, Mitgaard-Thomsen, A., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Povlsen, G. K., 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 103-114

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Activation of the renal GLP-1R leads to expression of Ren1 in the renal vascular tree

    Bjørnholm, K. D., Ougaard, M. E., Skovsted, Gry Freja, Knudsen, L. B. & Pyke, C., 2021, In: Endocrinology, Diabetes and Metabolism. 4, 3, e00234.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Decreased expression of the GLP-1 receptor after segmental artery injury in mice

    Bjørnholm, K. D., Povlsen, G. K., Ougaard, M. E., Pyke, C., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Skovsted, Gry Freja, 2021, In: The Journal of endocrinology. 248, 3, p. 289-301 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Vascular gene expression in diet-induced atherosclerotic Gottingen minipigs

    Christensen, Liv von Voss, Skovgaard, K., Ludvigsen, T. P., Kirk, R. K., Christoffersen, B. O., Pedersen, H. D., Heegaard, P. M. & Olsen, Lisbeth Høier, Jul 2015, In: Atherosclerosis. 241, 1, p. E85-E85 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  32. Published

    Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs

    Boonen, H. C. M., Moesgaard, S. G., Birck, M. M., Christoffersen, B. Ø., Cirera, Susanna, Heegaard, P. M. H., Højbøge, T. R., Jensen, Lars Jørn, Mortensen, A., Olsen, Lisbeth Høier, Sheykhzade, Majid, Tang, J. & Lykkesfeldt, Jens, 2014, In: Pflügers ARchiv (European Journal of Physiology). 466, 12, p. 2167-2176 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Generic immune complex assay for detection of murine anti-drug-antibodies in complex with human IgG

    Boysen, L., Sprinkel, A. M. E., Lauritzen, B., Breinholt, J., Lykkesfeldt, Jens, Viuff, B. M. & Landsy, L. H., 2019, In: Biologicals. 60, p. 42-48 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    An ELISA for detection of complement-bound circulating immune complexes in mice

    Boysen, L., Lauritzen, B., Viuff, B. M., Lykkesfeldt, Jens & Landsy, L. H., 2019, In: Journal of Immunotoxicology. 16, 1, p. 82-86 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Formation and Glomerular Deposition of Immune Complexes in Mice Administered Human Antibodies: Evaluation of Dose, Frequency, and Biomarkers

    Boysen, L., Viuff, B. M., Landsy, L. H., Lykkesfeldt, Jens, Raymond, J. T., Price, S. A., Pelzer, H. & Lauritzen, B., 2020, In: Toxicologic Pathology. 48, 4, p. 570-585 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Formation and glomerular deposition of immune complexes in mice administered bovine serum albumin: Evaluation of dose, frequency, and biomarkers

    Boysen, L., Viuff, B. M., Landsy, L. H., Price, S. A., Raymond, J. T., Lykkesfeldt, Jens & Lauritzen, B., 2019, In: Journal of Immunotoxicology. 16, 1, p. 191-200 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice

    Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, Ditte Olsen, Halling, Jens Frey, Hansen, M., Al-Soud, W. A., Hansen, Lars Hestbjerg, Kiilerich, P. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Increased meal-induced neurotensin response predicts successful maintenance of weight loss: Data from a randomized controlled trial

    Brethvad, Annemette Overgaard, Zakariassen, Hannah Louise, Holt, Joachim, Lundgren, J. R., Jakobsen, A., Hartmann, Bolette, Lehmann, E. W., Kissow, Hannelouise, Holst, Jens Juul, Madsbad, Sten, Torekov, Signe Sørensen & Holst, Birgitte, 2023, In: Metabolism: Clinical and Experimental. 143, 8 p., 155534.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Ascorbate status modulates reticuloendothelial iron stores and response to deferasirox iron chelation in ascorbate-deficient rats

    Brewer, C., Otto-Duessel, M., Lykkesfeldt, Jens, Nick, H. & Wood, J. C., 2012, In: Experimental Hematology. 40, 10, p. 820-827 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Co-bedding of Preterm Newborn Pigs Reduces Necrotizing Enterocolitis Incidence Independent of Vital Functions and Cortisol Levels

    Brunse, Anders, Peng, Y., Li, Y., Lykkesfeldt, Jens & Sangild, Per Torp, 2021, In: Frontiers in Pediatrics. 9, 636638.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    New records of gall midges (Diptera: Cecidomyiidae) from Denmark

    Bruun, Hans Henrik, Haarder, S., Jørgensen, J. & Skuhravá, M., 2014, In: Entomologiske Meddelelser. 82, 1, p. 25-37 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Immune reactions in fish against parasites from protozoans to metazoans

    Buchmann, Kurt, Chettri, J. K., Desmukh, S., Jaafar, Rzgar, Haarder, S., Bahlool, Q. Z. M., Jørgensen, L. G. & Kania, Per, 2013, In: Fish and Shellfish Immunology. 34, 6, p. 1641 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  43. Published

    Zebrafisken - en holistisk miljømodel

    Buchmann, Kurt, Kania, Per, Haarder, S. & Jørgensen, Louise von Gersdorff, 25 Jan 2016, Villum Fonden - Velux Fonden: årsskrift 2015. Søborg: Villum Fonden, p. 52-58 7 p. (Villum Fonden - Velux Fonden : årsskrift, Vol. 2015).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  44. Published

    Peri-operative endothelial dysfunction in patients undergoing minor abdominal surgery: An observational study

    Busch, S. V. E., Godthaab, C., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Gögenur, I., Feb 2019, In: European Journal of Anaesthesiology. 36, 2, p. 130-134 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Malnutrition predisposes to endotoxin-induced edema and impaired inflammatory response in parenterally fed piglets

    Bæk, Ole, Fabiansen, C., Friis, Henrik, Ritz, C., Koch, Jørgen, Willesen, Jakob, Heegaard, P. M. H., Lykkesfeldt, Jens, Briend, A., Golden, M. H., Sangild, Per Torp & Thymann, Thomas, 2020, In: Journal of Parenteral and Enteral Nutrition. 44, 4, p. 668-676

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

    Callø, Kirstine, Geryk, M., Freude, Kristine, Treat, J. A., Vold, V. A., Frederiksen, Henriette Reventlow S, Broendberg, A. K., Frederiksen, T. C., Jensen, H. K. & Cordeiro, J. M., 2022, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 24, 12, p. 2015–2027

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Implantation of telemetric blood pressure transmitters in Göttingen Minipigs: Validation of 24-h systemic blood pressure and heart rate monitoring and influence of anaesthesia

    Carlsen, M. F., Christoffersen, B. Ø., Lindgaard, R., Pedersen, H. D. & Olsen, Lisbeth Høier, 2022, In: Journal of Pharmacological and Toxicological Methods. 115, 107168.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Discrepancies in global vitamin C recommendations: a review of RDA criteria and underlying health perspectives

    Carr, A. C. & Lykkesfeldt, Jens, 2021, In: Critical Reviews in Food Science and Nutrition. 61, 5, p. 742-755 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  49. Published

    Factors Affecting the Vitamin C Dose-Concentration Relationship: Implications for Global Vitamin C Dietary Recommendations

    Carr, A. C. & Lykkesfeldt, Jens, 2023, In: Nutrients. 15, 7, 19 p., 1657.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Vitamin C: From Bench to Bedside

    Carr, A. C. & Lykkesfeldt, Jens, 2021, In: Nutrients. 13, 4, 3 p., 1102.

    Research output: Contribution to journalEditorialResearchpeer-review

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