- Published
Plasma lipid oxidation predicts atherosclerotic status better than cholesterol in diabetic apolipoprotein E deficient mice
Petersen, Karen Ekkelund, Lykkesfeldt, Jens, Raun, K. & Rakipovski, G., Jan 2017, In: Experimental Biology and Medicine (Maywood). 242, 1, p. 88-91Research output: Contribution to journal › Journal article › Research › peer-review
- Published
35Sulphate incorporation assay as a new tool for measuring early cartilage degradation following blood exposure in vitro and in vivo in f8 ko rats
Pulles, A. E., Christensen, K. R., Coeleveld, K., Kjelgaard-Hansen, M., Schutgens, R. E., Lafeber, F. P., Roepstorff, K. & Mastbergen, S. C., Apr 2017, In: Osteoarthritis and Cartilage. 25, S1, p. S156-S157Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Proteoglycan synthesis rate as a novel method to measure blood-induced cartilage degeneration in non-haemophilic and haemophilic rats
Pulles, A. E., Vøls, Kåre Kryger, Christensen, K. R., Coeleveld, K., Hansen, Axel Kornerup, van Vulpen, L. F. D., Petersen, M., Mastbergen, S. C., Roepstorff, K., Schutgens, R. E. G., Kjelgaard-Hansen, M. & Lafeber, F. P. J. G., 2020, In: Haemophilia. 26, 3, p. e88-e96Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pulsatile Hyperglycaemia Induces Vascular Oxidative Stress and GLUT 1 Expression More Potently than Sustained Hyperglycaemia in Rats on High Fat Diet
Rakipovski, G., Lykkesfeldt, Jens & Raun, K., 20 Jan 2016, In: P L o S One. 11, 1, e0147412.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fluctuating hyperglycaemia increases oxidative stress response in lean rats compared to sustained hyperglycaemia despite lower glycaemic exposure
Rakipovski, G., Raun, K. & Lykkesfeldt, Jens, 2011, In: Diabetes and Vascular Disease Research. 8, 4, p. 295-298 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heart rate, heart rate variability, and arrhythmias in dogs with myxomatous mitral valve disease
Rasmussen, C. E., Falk, B. T., Zois, N. E., Moesgaard, S. G., Häggström, J., Pedersen, H. D., Åblad, B., Nilsen, H. Y. & Olsen, Lisbeth Høier, 2012, In: Journal of Veterinary Internal Medicine. 26, 1, p. 76-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Holter monitoring of small breed dogs with advanced myxomatous mitral valve disease with and without a history of syncope
Rasmussen, C. E., Falk, B. T., Petrič, A. D., Schaldemose, M., Zois, N. E., Moesgaard, S. G., Åblad, B., Nielsen, H. Y., Ljungvall, I., Höglund, K., Häggström, J., Pedersen, H. D., Bland, J. M. & Olsen, Lisbeth Høier, 2014, In: Journal of Veterinary Internal Medicine. 28, 2, p. 363-370 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development
Rasmussen, K. K., Skat-Rørdam, Josephine, Andersen, P., Warzecha, C. B., Pye, M., Andersen, T. A., Ajbro, K. D., Bendsen, E., Narimatsu, M., Vilhardt, Frederik, Pedersen, Lotte Bang, Wrana, J. L., Anderson, R. H., Møllgård, Kjeld, Christensen, Søren Tvorup & Larsen, Lars Allan, 2018, In: Scientific Reports. 8, 1, 14 p., 9542.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simvastatin and oxidative stress in humans: A randomized, double-blinded, placebo-controlled clinical trial
Rasmussen, S. T., Andersen, Jon Thor Trærup, Nielsen, T. K., Cejvanovic, V., Petersen, K. M., Henriksen, T., Weimann, A., Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2016, In: Redox Biology. 9, p. 32-38Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of left ventricular hypertrophy in a novel porcine model of mitral regurgitation
Ravn, N., Zois, N. E., Moesgaard, S. G., Hønge, J. L., Smerup, M. H., Hasenkam, J. M., Sloth, E., Cremer, Signe Emilie & Olsen, Lisbeth Høier, 2014, In: Scandinavian Cardiovascular Journal. 48, 3, p. 189-195 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitral Regurgitation Severity and Left Ventricular Systolic Dimension Predict Survival in Young Cavalier King Charles Spaniels
Reimann, Maria Josefine, Moller, J. E., Haggstrom, J., Martinussen, Torben, Zatrazemi, S. S. C., Svanholm, L., Nielsen, L. B. M., Pedersen, H. D. & Olsen, Lisbeth Høier, 2017, In: Journal of Veterinary Internal Medicine. 31, 4, p. 1008-1016 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Markers of Oxidative Stress in Dogs with Myxomatous Mitral Valve Disease are Influenced by Sex, Neuter Status, and Serum Cholesterol Concentration
Reimann, Maria Josefine, Haggstrom, J., Moller, J. E., Lykkesfeldt, Jens, Falk, T. & Olsen, Lisbeth Høier, 2017, In: Journal of Veterinary Internal Medicine. 31, 2, p. 295-302 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased serum C-reactive protein concentrations in dogs with congestive heart failure due to myxomatous mitral valve disease
Reimann, Maria Josefine, Ljungvall, I., Hillstrom, A., Møller, J. E., Hagman, R., Falk, T., Hoglund, K., Haggstrom, J. & Olsen, Lisbeth Høier, Mar 2016, In: Veterinary Journal. 209, p. 113-118Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intermittent mitral regurgitation in Cavalier King Charles spaniels: Short-term progression and influence of stress tests
Reimann, Maria Josefine, Møller, J. E., Häggström, J., Åkerström, L. L. B., Martinussen, Torben & Olsen, Lisbeth Høier, 2020, In: Veterinary Journal. 258, 105457.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease
Reimann, Maria Josefine, Fredholm, Merete, Cremer, Signe Emilie, Christiansen, L. B., Meurs, K. M., Møller, J. E., Häggström, J., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Journal of Veterinary Internal Medicine. 35, 6, p. 2596-2606Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No impact of polymorphism in the phosphodiesterase 5A gene in Cavalier King Charles Spaniels on pimobendan-induced inhibition of platelet aggregation response
Reimann, Maria Josefine, Faisst, D. N., Knold, M., Meurs, K. M., Stern, J. A., Cremer, Signe Emilie, Møller, J. E., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2023, In: Journal of Veterinary Internal Medicine. 37, 6, p. 1947-2660Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitral valve transcriptome analysis in thirty-four age-matched Cavalier King Charles Spaniels with or without congestive heart failure caused by myxomatous mitral valve disease
Reimann, Maria Josefine, Cremer, Signe Emilie, Christiansen, L., Ibragimov, Emil, Gao, Fei, Cirera, Susanna, Fredholm, Merete, Olsen, Lisbeth Høier & Karlskov-Mortensen, Peter, 2024, In: Mammalian Genome. 35, 1, p. 77-89 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
R-R interval variations influence the degree of mitral regurgitation in dogs with myxomatous mitral valve disease
Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: The Veterinary Journal. 199, 3, p. 348-354 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
R-R interval variations influence the degree of mitral regurgitation in dogs with myxomatous mitral valve disease
Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2013.Research output: Contribution to conference › Poster › Research
- Published
Biopterin status in dogs with myxomatous mitral valve disease is associated with disease severity and cardiovascular risk factors
Reimann, Maria Josefine, Häggström, J., Mortensen, A., Lykkesfeldt, Jens, Møller, J. E., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1520-1526 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Myxømatøs mitralklapsygdom hos hund: Medicinsk behandling
Reimann, Maria Josefine, Christiansen, L. B., Falk, B. T. & Olsen, Lisbeth Høier, 2019, In: Dansk Veterinaertidsskrift. 2019, 11, p. 38-43Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of R-R interval variations on the degree of mitral regurgitation in dogs with myxomatous mitral valve disease
Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2013, In: Journal of Veterinary Internal Medicine. 27, 3, p. 636-637 2 p., C-30.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Myxømatøs mitralklapsygdom hos hund: Metoder til diagnostik af behandlingskrævende sygdomsstadier
Reimann, Maria Josefine, Christiansen, L. B., Falk, T. & Olsen, Lisbeth Høier, 2019, In: Dansk Veterinaertidsskrift. 2019, 9, p. 28-32Research output: Contribution to journal › Review › Research › peer-review
- Published
Generation of eight hiPSCs lines from two pathogenic variants in CACNA1A using the CRISPR-Cas9 gene editing technology
Rivera-Sánchez, P., Søndergaard, L., Wathikthinnakon, Methi, B. D. Magnusson, H., Frederiksen, Henriette Reventlow S, Aabæk Hammer, F., Taleb, R., Christian Cassidy, C., Tranholm Bruun, M., Tümer, Asuman Zeynep, Holst, B., Brasch-Andersen, C., Møller, R., Freude, Kristine & Chandrasekaran, Abinaya, 2023, In: Stem Cell Research. 71, 103193.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antimicrobial drug penetration into the pulmonary epithelial lining fluid and muscle measured by microdialysis in anesthetized pigs
Rottbøll, Lisa Amanda Holm & Friis, C., Jul 2015, In: Journal of Veterinary Pharmacology and Therapeutics. 38, S1, p. 89 1 p., 1.12.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Microdialysis as a tool for drug quantification in the bronchioles of anaesthetized pigs
Rottbøll, Lisa Amanda Holm & Friis, C., 2014, In: Basic & Clinical Pharmacology & Toxicology Online. 114, 3, p. 226-232 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intrabronchial microdialysis: effects of probe localization on tissue trauma and drug penetration into the pulmonary epithelial lining fluid
Rottbøll, Lisa Amanda Holm, Skovgaard, K., Barington, Kristiane, Jensen, Henrik Elvang & Friis, C., 2015, In: Basic & Clinical Pharmacology & Toxicology. 117, 4, p. 242-250 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Penetration of antimicrobials to pulmonary epithelial lining fluid and muscle and impact of drug physicochemical properties determined by microdialysis
Rottbøll, Lisa Amanda Holm & Friis, C., 2016, In: Journal of Pharmacological and Toxicological Methods. 78, p. 58-65 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines
Roursgaard, Martin, Knudsen, K. B., Northeved, H., Persson, M., Christensen, T., Kumar, P. E. K., Permin, A., Andresen, T. L., Gjetting, T., Lykkesfeldt, Jens, Vesterdal, L. K., Loft, Steffen & Møller, Peter, Oct 2016, In: Toxicology in Vitro. 36, p. 164-171 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulating the gut microbiota improves glucose tolerance, lipoprotein profile and atherosclerotic plaque development in ApoE-deficient mice
Rune, Ida, Rolin, B., Larsen, C. S., Nielsen, Dennis Sandris, Kanter, J. E., Bornfeldt, K. E., Lykkesfeldt, Jens, Buschard, K., Kirk, R. K., Christoffersen, B., Fels, J. J., Josefsen, K., Kihl, Pernille & Hansen, Axel Kornerup, 2016, In: P L o S One. 11, 1, 16 p., e0146439.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice
Rune, Ida, Hansen, Axel Kornerup, Ellekilde, M., Nielsen, Dennis Sandris & Hansen, C., Nov 2011. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Ampicillin-improved glucose tolerance in diet-induced obese C57BL/6NTac mice is age dependent
Rune, Ida, Hansen, Camilla Hartmann Friis, Ellekilde, M., Nielsen, Dennis Sandris, Skovgaard, K., Rolin, B. C., Lykkesfeldt, Jens, Josefsen, K., Christensen, B. T., Kihl, Pernille & Hansen, Axel Kornerup, 2013, In: Experimental Diabetes Research. 2013, 13 p., 319321.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics
Rune, Ida, Rolin, B., Lykkesfeldt, Jens, Nielsen, Dennis Sandris, Krych, Lukasz, Kanter, J. E., Bornfeldt, K. E., Kihl, Pernille, Buschard, K., Josefsen, K., Fels, J. J., Mortensen, A., Christoffersen, B., Kirk, R. K. & Hansen, Axel Kornerup, 2018, In: Scientific Reports. 8, 1, 12 p., 5416.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
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Maternal vitamin C deficiency during pregnancy results in transient fetal and placental growth retardation in guinea pigs: [Plus] erratum
Schjoldager, J. G., Paidi, M. D., Lindblad, M. M., Birck, M. M., Kjærgaard, A. B., Dantzer, V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2015, In: European Journal of Nutrition. 54, 4, p. 667-676 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prolonged maternal vitamin C deficiency overrides preferential fetal ascorbate transport but does not influence perinatal survival in guinea pigs
Schjoldager, J. G., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: British Journal of Nutrition. 110, 9, p. 1573-1579 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of reduced and oxidized coenzyme Q10 in canine plasma and heart tissue by HPLC-ECD: Comparison with LC-MS/MS quantification
Schou-Pedersen, A. M. V., Schemeth, D. & Lykkesfeldt, Jens, 2019, In: Antioxidants. 8, 8, 253.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous quantification of monoamine neurotransmitters and their biogenic metabolites intracellularly and extracellularly in primary neuronal cell cultures and in sub-regions of guinea pig brain
Schou-Pedersen, A. M. V., Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 15 Aug 2016, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1028, p. 222-230 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of Three Sample Preparation Procedures for the Quantification of L-Arginine, Asymmetric Dimethylarginine, and Symmetric Dimethylarginine in Human Plasma Using HPLC-FLD
Schou-Pedersen, A. M. V. & Lykkesfeldt, Jens, 1 Feb 2018, In: Journal of Analytical Methods in Chemistry. 2018, 7 p., 6148515.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Experimental non-alcoholic steatohepatitis in Göttingen Minipigs: Consequences of high fat-fructose-cholesterol diet and diabetes
Schumacher-Petersen, Camilla, Christoffersen, B. O., Kirk, R. K., Ludvigsen, T. P., Zois, N. E., Pedersen, H. D., Vyberg, M. & Olsen, Lisbeth Høier, 2019, In: Journal of Translational Medicine. 17, 1, 110.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An improved method for lifting and transporting anesthetized pigs within an animal facility
Schumacher-Petersen, Camilla, Hammelev, Karsten Pharao & Flescher, Jens, Jul 2014, In: Lab Animal. 43, 7, p. 237-41 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
IL-33 promotes GATA-3 polarization of gut-derived T cells in experimental and ulcerative colitis
Seidelin, Jakob Benedict, Coskun, M., Kvist, P. H., Holm, T. L., Holgersen, Kristine & Nielsen, Ole Haagen, Feb 2015, In: Journal of Gastroenterology. 50, 2, p. 180-190 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Welcome to Basic & Clinical Pharmacology & Toxicology 2024
Simonsen, U. & Lykkesfeldt, Jens, 2024, In: Basic and Clinical Pharmacology and Toxicology. 134, 1, p. 126-128Research output: Contribution to journal › Journal article › Research
- Published
Charting a new course: A vision for the future as editors-in-chief
Simonsen, U. & Lykkesfeldt, Jens, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 4, p. 390 1 p.Research output: Contribution to journal › Editorial › Research
- Published
A role of peroxisome proliferator-activated receptor gamma in non-alcoholic fatty liver disease
Skat-Rørdam, Josephine, Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, May 2019, In: Basic & Clinical Pharmacology & Toxicology. 124, 5, p. 528-537Research output: Contribution to journal › Review › Research › peer-review
- Published
Vitamin C deficiency may delay diet-induced NASH regression in the guinea pig
Skat-Rørdam, Josephine, Pedersen, Kamilla, Skovsted, Gry Freja, Gregersen, I., Vangsgaard, S., Ipsen, David Højland, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Antioxidants. 11, 1, 69.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modelling Nonalcoholic Steatohepatitis In Vivo—A Close Transcriptomic Similarity Supports the Guinea Pig Disease Model
Skat-Rørdam, Josephine, Ipsen, David Højland, Seemann, Ernst Stefan, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 9, 18 p., 1198.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of dietary components on glucose intolerance and non‐alcoholic steatohepatitis
Skat-Rørdam, Josephine, Ipsen, David Højland, Hardam, P. D., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Nutrients. 13, 8, 2523.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modelling nonalcoholic steatohepatitis in vivo—a close transcriptomic similarity supports the guinea pig disease model
Skat-Rørdam, Josephine, Ipsen, David Højland, Seemann, Ernst Stefan, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, Sep 2021, In: Biomedicines. 9, 9, 1198.Research output: Contribution to journal › Journal article › Research › peer-review
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Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
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Increased systemic oxidatively generated DNA and RNA damage in schizophrenia
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Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
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