Lifepharm

  1. 2014
  2. Published

    An oxazolone zebrafish model for inflammatory bowel disease (IBD): preliminary results

    Haarder, S., Kania, Per, Hyttel, P., Lindebo Holm, T. & Buchmann, Kurt, 2014.

    Research output: Contribution to conferencePosterResearchpeer-review

  3. Published

    Increased Contracaecum osculatum infection in Baltic cod (Gadus morhua) livers (1982-2012) associated with increasing grey seal (Halichoerus gryphus) populations.

    Haarder, S., Kania, Per, Galatius, A. & Buchmann, Kurt, 2014, In: Journal of Wildlife Diseases. 50, 3, p. 537-543 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Zebra fish as a model for inflammatory bowel disease (IBD): preliminary results

    Haarder, S., Kania, Per, Hyttel, P., Lindebo Holm, T. & Buchmann, Kurt, Nov 2014.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  5. Published

    Melatonin does not affect oxidative/inflammatory biomarkers in a closed-chest porcine model of acute myocardial infarction

    Halladin, N. L., Busch, S. V. E., Jensen, S. E., Aarøe, J., Kjærgaard, B., Heegaard, P. M. H., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, p. 483-488 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Does vitamin C deficiency affect cognitive development and function?

    Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 9, p. 3818-3846 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Associations between N-terminal procollagen type III, fibrosis and echocardiographic indices in dogs that died due to myxomatous mitral valve disease

    Hezzell, M. J., Falk, B. T., Olsen, Lisbeth Høier, Boswood, A. & Elliott, J., 2014, In: Journal of Veterinary Cardiology. 16, 4, p. 257-264 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Characterisation of enterocolitis in the piroxicam-accelerated interleukin-10 knock out mouse: a model mimicking inflammatory bowel disease

    Holgersen, Kristine, Kvist, P. H., Markholst, H., Hansen, Axel Kornerup & Holm, T. L., 2014, In: Journal of Crohn's and Colitis. 8, 2, p. 147-160 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Predictive validity and immune cell involvement in the pathogenesis of piroxicam-accelerated colitis in interleukin-10 knockout mice

    Holgersen, Kristine, Kvist, P. H., Hansen, Axel Kornerup & Holm, T. L., 2014, In: International Immunopharmacology. 21, 1, p. 137-147 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Validation of Piroxicam-Accelerated Colitis in the Interleukin-10 Knock out Mouse - a Preclinical Model Mimicking Human Inflammatory Bowel Disease

    Holgersen, Kristine, Kvist, P. H., Hansen, Axel Kornerup & Holm, T. L., May 2014.

    Research output: Contribution to conferencePosterResearchpeer-review

  11. Published

    Pig models for the human heart failure syndrome

    Hunter, I., Terzic, D., Zois, N. E., Olsen, Lisbeth Høier & Gøtze, J. P., 2014, In: Cardiovascular Endocrinology. 3, 1, p. 15-18 4 p.

    Research output: Contribution to journalReviewResearchpeer-review

  12. Published

    Canine mitral valve disease: From genetics through screening programs, to practical breeding advice

    Häggström, J., Swift, S. & Olsen, Lisbeth Høier, 2014.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  13. Published

    Does vitamin C deficiency promote fatty liver disease development?

    Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 12, p. 5473-5499 27 p.

    Research output: Contribution to journalReviewResearchpeer-review

  14. Published

    Potassium and calcium channel gene expression in small arteries in porcine and rat models of diet-induced obesity (Poster)

    Jensen, Lars Jørn, Salomonsson, M., Sorensen, Charlotte Mehlin, von Holstein-Rathlou, Niels-Henrik, Pedersen, H. D., Christoffersen, B. Ø., Olsen, Lisbeth Høier & Ludvigsen, Trine Pagh, 27 Apr 2014, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28, Supplement 1, 1 p., 676.4.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  15. Published

    Effect of insulin-induced hypoglycaemia on the central nervous system: evidence from experimental studies

    Jensen, Vivi Flou Hjorth, Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 3, p. 123-150 28 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Effect of insulin-induced hypoglycaemia on the peripheral nervous system: focus on adaptive mechanisms, pathogenesis and histopathological changes

    Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 8, p. 482-496 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats

    Knudsen, K. B., Northeved, H., Gjetting, T., Permin, A., Andresen, T. L., Wegener, K. M., Rye Lam, H. & Lykkesfeldt, Jens, 2014, In: Journal of Nanoparticle Research. 16, 1, 11 p., 2221.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Differential toxicological response to positively and negatively charged nanoparticles in the rat brain

    Knudsen, K. B., Northeved, H., Ek, P. K., Permin, A., Andresen, T. L., Larsen, S., Wegener, K. M., Lam, H. R. & Lykkesfeldt, Jens, 2014, In: Nanotoxicology. 8, 7, p. 764-774 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Development and Characterization of an Atherosclerotic Minipig Model

    Ludvigsen, Trine Pagh, 2014, Copenhagen University.

    Research output: Book/ReportPh.D. thesisResearch

  20. Published

    Noninvasive assessment of pulse-wave velocity and flow-mediated vasodilation in anesthetized Göttingen minipigs

    Ludvigsen, Trine Pagh, Wiinberg, N., Jensen, C. J., Callesen, A. T., Andersen, R. W., Jørgensen, A. S. H., Christoffersen, B. Ø., Pedersen, H. D., Moesgaard, S. G. & Olsen, Lisbeth Høier, 2014, In: Comparative Medicine. 64, 6, p. 471-477 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Vitamin C

    Lykkesfeldt, Jens, Michels, A. J. & Frei, B., 2014, In: Advances in Nutrition. 5, 1, p. 16-18 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Matrix metalloproteinases (MMPs), tissue inhibitors of metalloproteinases (TIMPs) and transforming growth factor-β (TGF-β) in advanced canine myxomatous mitral valve disease

    Moesgaard, S. G., Aupperle, H., Rajamäki, M. M., Falk, T., Rasmussen, C. E., Zois, N. E. & Olsen, Lisbeth Høier, 2014, In: Research in Veterinary Science. 97, 3, p. 560-567 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies

    Mortensen, A. & Lykkesfeldt, Jens, 2014, In: Nitric Oxide: Biology and Chemistry. 36, p. 51-57 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    Positive charge, negative effect: the impact of cationic nanoparticles in the brain

    Møller, Peter & Lykkesfeldt, Jens, Jul 2014, In: Nanomedicine. 9, 10, p. 1441-3 3 p.

    Research output: Contribution to journalEditorialResearchpeer-review

  25. Published

    Advances in targeted delivery of small interfering RNA using simple bioconjugates

    Nielsen, C., Kjems, J., Sørensen, K. R., Engelholm, Lars Henning & Behrendt, Niels, 2014, In: Expert Opinion on Drug Delivery. 11, 5, p. 791-822 32 p.

    Research output: Contribution to journalReviewResearchpeer-review

  26. Published

    Cardiovascular of Inflammatory Disease Models: In vivo imaging, Pathology and Pharmacology

    Olsen, Lisbeth Høier, Nielsen, O. L., Hunter, I., Falk, B. T., Cremer, Signe Emilie, Ludvigsen, Trine Pagh, Reimann, Maria Josefine, Olsen, H. G., Nielsen, K. M., Laursen, H., Kronborg, S. & Kjempff, C. T., 2014.

    Research output: Contribution to conferencePosterCommunication

  27. Published

    Chronic vitamin C deficiency promotes redox imbalance in the brain but does not alter sodium-dependent vitamin C transporter 2 expression

    Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrients. 6, 5, p. 1809-1822 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Prenatal vitamin C deficiency results in differential levels of oxidative stress during late gestation in foetal guinea pig brains

    Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Redox Biology. 2, p. 361-367 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Feasibility of simultaneous PET/MR in diet-induced atherosclerotic minipig: a pilot study for translational imaging

    Pedersen, S. F., Ludvigsen, Trine Pagh, Johannesen, Helle Hjorth, Löfgren, J., Ripa, Rasmus Sejersten, Hansen, Adam Espe, Ettrup, A. J., Christoffersen, B. Ø., Pedersen, H. D., Olsen, Lisbeth Høier, Højgaard, Liselotte & Kjær, Andreas, 2014, In: American Journal of Nuclear Medicine and Molecular Imaging. 4, 5, p. 448-58 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Holter monitoring of small breed dogs with advanced myxomatous mitral valve disease with and without a history of syncope

    Rasmussen, C. E., Falk, B. T., Petrič, A. D., Schaldemose, M., Zois, N. E., Moesgaard, S. G., Åblad, B., Nielsen, H. Y., Ljungvall, I., Höglund, K., Häggström, J., Pedersen, H. D., Bland, J. M. & Olsen, Lisbeth Høier, 2014, In: Journal of Veterinary Internal Medicine. 28, 2, p. 363-370 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Development of left ventricular hypertrophy in a novel porcine model of mitral regurgitation

    Ravn, N., Zois, N. E., Moesgaard, S. G., Hønge, J. L., Smerup, M. H., Hasenkam, J. M., Sloth, E., Cremer, Signe Emilie & Olsen, Lisbeth Høier, 2014, In: Scandinavian Cardiovascular Journal. 48, 3, p. 189-195 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Biopterin status in dogs with myxomatous mitral valve disease is associated with disease severity and cardiovascular risk factors

    Reimann, Maria Josefine, Häggström, J., Mortensen, A., Lykkesfeldt, Jens, Møller, J. E., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1520-1526 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    R-R interval variations influence the degree of mitral regurgitation in dogs with myxomatous mitral valve disease

    Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: The Veterinary Journal. 199, 3, p. 348-354 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Microdialysis as a tool for drug quantification in the bronchioles of anaesthetized pigs

    Rottbøll, Lisa Amanda Holm & Friis, C., 2014, In: Basic & Clinical Pharmacology & Toxicology Online. 114, 3, p. 226-232 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    An improved method for lifting and transporting anesthetized pigs within an animal facility

    Schumacher-Petersen, Camilla, Hammelev, Karsten Pharao & Flescher, Jens, Jul 2014, In: Lab Animal. 43, 7, p. 237-41 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    In vivo vitamin C deficiency in guinea pigs increases ascorbate transporters in liver but not kidney and brain

    Søgaard, D., Lindblad, M. M., Paidi, M. D., Andersen, S. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrition Research. 34, 7, p. 639-645 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The kidneys play an important role in the clearance of rFVIIa in rats

    Vestergaard, Bill, Appa, R. S., Lykkesfeldt, Jens & Agersø, H., 2014, In: Thrombosis Research. 133, 6, p. 1124-1129 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Echocardiographic assessment of left ventricular function in mitral regurgitation: is the dog a useful model of man?

    Zois, N. E., Pedersen, H. D., Häggström, J. & Olsen, Lisbeth Høier, 2014, In: Cardiovascular Endocrinology. 3, 1, p. 9-14 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published

    Natriuretic peptides in cardiometabolic regulation and disease

    Zois, N. E., Bartels, E. D., Hunter, I., Kousholt, B. S., Olsen, Lisbeth Høier & Gøtze, J. P., 2014, In: Nature Reviews Cardiology. 11, 7, p. 403-412 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  40. 2013
  41. Published

    Circadian Variation in the Response to Experimental Endotoxemia and Modulatory Effects of Exogenous Melatonin

    Alamili, M., Klein, M., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2013, In: Chronobiology International. 30, 9, p. 1174-1180 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Inflammation and bone remodeling in the delayed-type hypersensitivity (DTH) arthritis model

    Atkinson, S. M., Thorn, M., Autzen Usher, P., Fox, B., Serikawa, K., Biswas, S., Haase, C., Skov, Søren & Nansen, A., 2013, In: Scandinavian Journal of Immunology. 77, 4, p. 304

    Research output: Contribution to journalConference abstract in journalResearch

  43. Published

    Endothelial cell death and intimal foam cell accumulation in the coronary artery of infected hypercholesterolemic minipigs

    Birck, M. M., Saraste, A., Hyttel, P., Odermarsky, M., Liuba, P., Saukko, P., Hansen, Axel Kornerup & Pesonen, E., 2013, In: Journal of Cardiovascular Translational Research. 6, 4, p. 579-587 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Laparoscopic Roux-en-Y gastric bypass in super obese Göttingen minipigs

    Birck, M. M., Vegge, A., Støckel, M., Gögenur, Ismail, Thymann, Thomas, Hammelev, Karsten Pharao, Sangild, Per Torp, Hansen, Axel Kornerup, Raun, K., von Voss, P. & Eriksen, Thomas, 2013, In: American Journal of Translational Research. 5, 6, p. 643-653 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Evaluation of the breeding program aiming at reducing the prevalence of myxomatous mitral valve disease in Cavalier King Charles Spaniels in Denmark

    Birkegaard , A. C., Reimann, Maria Josefine, Häggström, J., Martinussen, Torben, Pedersen , H. D. & Olsen, Lisbeth Høier, 2013, American College of Veterinary Internal Medicine, Congress Proceedings. Sellon, R. K. & McClure, J. T. (eds.). Lakewood, p. 172 1 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  46. Published

    Immune reactions in fish against parasites from protozoans to metazoans

    Buchmann, Kurt, Chettri, J. K., Desmukh, S., Jaafar, Rzgar, Haarder, S., Bahlool, Q. Z. M., Jørgensen, L. G. & Kania, Per, 2013, In: Fish and Shellfish Immunology. 34, 6, p. 1641 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  47. Published

    Whey protein reduces early life weight gain in mice fed a high-fat diet

    Christensen, B. T., Hellgren, L., Lykkesfeldt, Jens, Sejrsen, K., Jeamet, A., Rune, Ida, Ellekilde, M., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2013, In: PLOS ONE. 8, 8, 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Plasma proANP and SDMA and microRNAs are associated with chronic mitral regurgitation in a pig model

    Cirera, Susanna, Moesgaard, S. G., Zois, N. E., Ravn, N., Goetze, Jens P. , Cremer, Signe Emilie, Teerlink, T., Leifsson, Páll S., Honge, J. L., Hasenkam, J. M. & Olsen, Lisbeth Høier, 2013, In: Endocrine Connections. 2, 3, p. 161-171 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Cardiac troponin-I concentration, myocardial arteriosclerosis, and fibrosis in dogs with congestive heart failure because of Myxomatous Mitral Valve Disease

    Falk, B. T., Ljungvall, I., Zois, N. E., Höglund, K., Olsen, Lisbeth Høier, Pedersen, H. D. & Häggström, J., 2013, In: Journal of Veterinary Internal Medicine. 27, 3, p. 500-506 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Pigs in space

    Goetze, J. P., Hunter, I., Smith, J. & Hasenkam, J. M., 2013, In: Cardiovascular Endocrinology. 2, 1, p. 4-5 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Comparative infectivity of three larval nematode species in three different salmonids

    Haarder, S., Kania, Per & Buchmann, Kurt, 2013, In: Parasitology Research. 112, 8, p. 2997-3004 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Expression of immune relevant genes in rainbow trout following exposure to live Anisakis simplex larvae

    Haarder, S., Kania, Per, Bahlool, Q. Z. M. & Buchmann, Kurt, 2013, In: Experimental Parasitology. 135, 3, p. 564-569 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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