Lifepharm

  1. 2014
  2. Published

    Differential toxicological response to positively and negatively charged nanoparticles in the rat brain

    Knudsen, K. B., Northeved, H., Ek, P. K., Permin, A., Andresen, T. L., Larsen, S., Wegener, K. M., Lam, H. R. & Lykkesfeldt, Jens, 2014, In: Nanotoxicology. 8, 7, p. 764-774 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Does vitamin C deficiency affect cognitive development and function?

    Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 9, p. 3818-3846 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Does vitamin C deficiency promote fatty liver disease development?

    Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 12, p. 5473-5499 27 p.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies

    Mortensen, A. & Lykkesfeldt, Jens, 2014, In: Nitric Oxide: Biology and Chemistry. 36, p. 51-57 7 p.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Echocardiographic assessment of left ventricular function in mitral regurgitation: is the dog a useful model of man?

    Zois, N. E., Pedersen, H. D., Häggström, J. & Olsen, Lisbeth Høier, 2014, In: Cardiovascular Endocrinology. 3, 1, p. 9-14 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    Effect of insulin-induced hypoglycaemia on the central nervous system: evidence from experimental studies

    Jensen, Vivi Flou Hjorth, Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 3, p. 123-150 28 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Effect of insulin-induced hypoglycaemia on the peripheral nervous system: focus on adaptive mechanisms, pathogenesis and histopathological changes

    Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 8, p. 482-496 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Effect of melatonin on human nighttime endotoxaemia: randomized, double-blinded, cross-over study

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, 6, p. 1057-1063 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Feasibility of simultaneous PET/MR in diet-induced atherosclerotic minipig: a pilot study for translational imaging

    Pedersen, S. F., Ludvigsen, Trine Pagh, Johannesen, Helle Hjorth, Löfgren, J., Ripa, Rasmus Sejersten, Hansen, Adam Espe, Ettrup, A. J., Christoffersen, B. Ø., Pedersen, H. D., Olsen, Lisbeth Høier, Højgaard, Liselotte & Kjær, Andreas, 2014, In: American Journal of Nuclear Medicine and Molecular Imaging. 4, 5, p. 448-58 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs

    Boonen, H. C. M., Moesgaard, S. G., Birck, M. M., Christoffersen, B. Ø., Cirera, Susanna, Heegaard, P. M. H., Højbøge, T. R., Jensen, Lars Jørn, Mortensen, A., Olsen, Lisbeth Høier, Sheykhzade, Majid, Tang, J. & Lykkesfeldt, Jens, 2014, In: Pflügers ARchiv (European Journal of Physiology). 466, 12, p. 2167-2176 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    High-fat feeding increases hepatic vitamin C synthesis and its circulatory mobilization in mice

    Christensen, B. T., Hansen, Axel Kornerup & Lykkesfeldt, Jens, 2014, In: European Journal of Nutrition. 53, 6, p. 1441-1444 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    High-level serotonin binding in subpopulation of highly activated platelets in cavalier King charles spaniels with myxomatous mitral valve disease

    Cremer, Signe Emilie, Kristensen, Annemarie T., Reimann, Maria Josefine, Eriksen, N. B., Petersen, S. F., Marschner, C. B., Tarnow, I., Oyama, M. A. & Olsen, Lisbeth Høier, 2014.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  14. Published

    High-level serotonin-binding in subpopulation of highly-activated platelets in Cavalier King Charles Spaniels with myxomateous valve disease

    Cremer, S. E., Kristensen, Annemarie T., Reimann, M. J., Eriksen, N. B., Petersen, S. F., Marschner, C. B., Tarnow, I., Oyama, M. A. & Olsen, Lisbeth Høier, 2014. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  15. Published

    Holter monitoring of small breed dogs with advanced myxomatous mitral valve disease with and without a history of syncope

    Rasmussen, C. E., Falk, B. T., Petrič, A. D., Schaldemose, M., Zois, N. E., Moesgaard, S. G., Åblad, B., Nielsen, H. Y., Ljungvall, I., Höglund, K., Häggström, J., Pedersen, H. D., Bland, J. M. & Olsen, Lisbeth Høier, 2014, In: Journal of Veterinary Internal Medicine. 28, 2, p. 363-370 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    In vivo vitamin C deficiency in guinea pigs increases ascorbate transporters in liver but not kidney and brain

    Søgaard, D., Lindblad, M. M., Paidi, M. D., Andersen, S. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrition Research. 34, 7, p. 639-645 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Increased Contracaecum osculatum infection in Baltic cod (Gadus morhua) livers (1982-2012) associated with increasing grey seal (Halichoerus gryphus) populations.

    Haarder, S., Kania, Per, Galatius, A. & Buchmann, Kurt, 2014, In: Journal of Wildlife Diseases. 50, 3, p. 537-543 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Matrix metalloproteinases (MMPs), tissue inhibitors of metalloproteinases (TIMPs) and transforming growth factor-β (TGF-β) in advanced canine myxomatous mitral valve disease

    Moesgaard, S. G., Aupperle, H., Rajamäki, M. M., Falk, T., Rasmussen, C. E., Zois, N. E. & Olsen, Lisbeth Høier, 2014, In: Research in Veterinary Science. 97, 3, p. 560-567 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Melatonin does not affect oxidative/inflammatory biomarkers in a closed-chest porcine model of acute myocardial infarction

    Halladin, N. L., Busch, S. V. E., Jensen, S. E., Aarøe, J., Kjærgaard, B., Heegaard, P. M. H., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, p. 483-488 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Melatonin suppresses markers of inflammation and oxidative damage in a human daytime endotoxemia model

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: Journal of Critical Care. 29, 1, p. 184.e9-184.e13 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Microdialysis as a tool for drug quantification in the bronchioles of anaesthetized pigs

    Rottbøll, Lisa Amanda Holm & Friis, C., 2014, In: Basic & Clinical Pharmacology & Toxicology Online. 114, 3, p. 226-232 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Natriuretic peptides in cardiometabolic regulation and disease

    Zois, N. E., Bartels, E. D., Hunter, I., Kousholt, B. S., Olsen, Lisbeth Høier & Gøtze, J. P., 2014, In: Nature Reviews Cardiology. 11, 7, p. 403-412 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  23. Published

    Neonatal Vitamin C Deficiency and Impaired Brain Development: A Dose-response Study

    Andersen, S. H., 2014, Copenhagen University.

    Research output: Book/ReportPh.D. thesisResearch

  24. Published

    New records of gall midges (Diptera: Cecidomyiidae) from Denmark

    Bruun, Hans Henrik, Haarder, S., Jørgensen, J. & Skuhravá, M., 2014, In: Entomologiske Meddelelser. 82, 1, p. 25-37 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Non-terminal blood sampling techniques in Guinea pigs

    Birck, M. M., Tveden-Nyborg, Pernille, Lindblad, M. M. & Lykkesfeldt, Jens, 2014, In: Journal of Visualized Experiments. 92, e51982.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Noninvasive assessment of pulse-wave velocity and flow-mediated vasodilation in anesthetized Göttingen minipigs

    Ludvigsen, Trine Pagh, Wiinberg, N., Jensen, C. J., Callesen, A. T., Andersen, R. W., Jørgensen, A. S. H., Christoffersen, B. Ø., Pedersen, H. D., Moesgaard, S. G. & Olsen, Lisbeth Høier, 2014, In: Comparative Medicine. 64, 6, p. 471-477 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Pig models for the human heart failure syndrome

    Hunter, I., Terzic, D., Zois, N. E., Olsen, Lisbeth Høier & Gøtze, J. P., 2014, In: Cardiovascular Endocrinology. 3, 1, p. 15-18 4 p.

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Predictive validity and immune cell involvement in the pathogenesis of piroxicam-accelerated colitis in interleukin-10 knockout mice

    Holgersen, Kristine, Kvist, P. H., Hansen, Axel Kornerup & Holm, T. L., 2014, In: International Immunopharmacology. 21, 1, p. 137-147 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Prenatal vitamin C deficiency results in differential levels of oxidative stress during late gestation in foetal guinea pig brains

    Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Redox Biology. 2, p. 361-367 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Pronounced inflammatory response to endotoxaemia during nighttime: a randomised cross-over trial

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, I., 2014, In: PloS one. 9, 1, 7 p., e87413.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    R-R interval variations influence the degree of mitral regurgitation in dogs with myxomatous mitral valve disease

    Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: The Veterinary Journal. 199, 3, p. 348-354 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Serotonin concentration is elevated in platelet-rich plasma and left ventricular myocardial and mitral valve leaflet tissue in dogs with myxomatous mitral valve disease

    Cremer, Signe Emilie, Singletary, G. E., Olsen, Lisbeth Høier, Wallace, K., Häggström, J., Ljungvall, I., Höglund, K., Reynolds, C. A., Pizzinat, N. & Oyama, M. A., 2014.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  33. Published

    Serotonin concentrations in platelets, plasma, mitral valve leaflet, and left ventricular myocardial tissue in dogs with myxomatous mitral valve disease

    Cremer, Signe Emilie, Singletary, G. E., Olsen, Lisbeth Høier, Wallace, K., Häggström, J., Ljungvall, I., Höglund, K., Reynolds, C. A., Pizzinat, N. & Oyama, M. A., 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1534-1540 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Strong association between activated valvular interstitial cells and histopathological lesions in porcine model of induced mitral regurgitation

    Cremer, Signe Emilie, Zois, N. E., Moesgaard, S. G., Ravn, N., Cirera, Susanna, Honge, J. L., Smerup, M. H., Hasenkam, J. M., Sloth, E., Leifsson, Páll S., Falk, B. T., Oyama, M. A., Orton, C., Martinussen, Torben & Olsen, Lisbeth Høier, 2014, In: International Journal of Cardiology. 174, 2, p. 443-446 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  35. Published

    The kidneys play an important role in the clearance of rFVIIa in rats

    Vestergaard, Bill, Appa, R. S., Lykkesfeldt, Jens & Agersø, H., 2014, In: Thrombosis Research. 133, 6, p. 1124-1129 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The role of neutrophils and G-CSF in DNFB-induced contact hypersensitivity in mice

    Christensen, A. D., Skov, Søren & Haase, C., 2014, In: Immunity, Inflammation and Disease. 2, 1, p. 21-34 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Transfer of gut microbiota from lean and obese mice to antibiotic-treated mice

    Ellekilde, M., Selfjord, E. M., Larsen, C. S., Jakesevic, M., Rune, Ida, Christensen, B. T., Vogensen, Finn Kvist, Nielsen, Dennis Sandris, Bahl, M. I., Licht, T. R., Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2014, In: Scientific Reports. 4, 8 p., 5922.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Vitamin C

    Lykkesfeldt, Jens, Michels, A. J. & Frei, B., 2014, In: Advances in Nutrition. 5, 1, p. 16-18 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2013
  40. Published

    Ampicillin-improved glucose tolerance in diet-induced obese C57BL/6NTac mice is age dependent

    Rune, Ida, Hansen, Camilla Hartmann Friis, Ellekilde, M., Nielsen, Dennis Sandris, Skovgaard, K., Rolin, B. C., Lykkesfeldt, Jens, Josefsen, K., Christensen, B. T., Kihl, Pernille & Hansen, Axel Kornerup, 2013, In: Experimental Diabetes Research. 2013, 13 p., 319321.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Cardiac natriuretic peptide gene expression and plasma concentrations during the first 72 hours of life in piglets

    Smith, J., Christoffersen, Christina, Nørgaard, L. M., Olsen, Lisbeth Høier, Vejlstrup, N. G., Andersen, C. B. & Gøtze, J. P., 2013, In: Endocrinology. 154, 5, p. 1864-1872 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Cardiac troponin-I concentration, myocardial arteriosclerosis, and fibrosis in dogs with congestive heart failure because of Myxomatous Mitral Valve Disease

    Falk, B. T., Ljungvall, I., Zois, N. E., Höglund, K., Olsen, Lisbeth Høier, Pedersen, H. D. & Häggström, J., 2013, In: Journal of Veterinary Internal Medicine. 27, 3, p. 500-506 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Circadian Variation in the Response to Experimental Endotoxemia and Modulatory Effects of Exogenous Melatonin

    Alamili, M., Klein, M., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2013, In: Chronobiology International. 30, 9, p. 1174-1180 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Comparative infectivity of three larval nematode species in three different salmonids

    Haarder, S., Kania, Per & Buchmann, Kurt, 2013, In: Parasitology Research. 112, 8, p. 2997-3004 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Coronary flow and reactivity, but not arrhythmia vulnerability, are affected by cardioplegia during cardiopulmonary bypass in piglets

    Liuba, P., Johansson, S., Pesonen, E., Odermarsky, M., Hansen, Axel Kornerup, Forslid, A., Aburawi, E. H., Higgins, T., Birck, M. M. & Perez-de-Sa, V., 2013, In: Journal of Cardiothoracic Surgery. 8, 6 p., 157.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Decreased Right Ventricular Systolic Function in Dogs with Myxomatous Mitral Valve Disease

    Olsen, Lisbeth Høier, Reimann, Maria Josefine, Møller, J. E., Häggström, J., Jangdin, S. E., Falk, B. T., Uggla, T. & Zois, N. E., 2013, In: Journal of Veterinary Internal Medicine. 27, 3, p. 628-629 2 p., C6.

    Research output: Contribution to journalConference abstract in journalResearch

  47. Published

    Does vitamin C deficiency increase lifestyle-associated vascular disease progression? evidence based on experimental and clinical studies

    Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Antioxidants & Redox Signaling. 19, 17, p. 2084-2104 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Endothelial cell death and intimal foam cell accumulation in the coronary artery of infected hypercholesterolemic minipigs

    Birck, M. M., Saraste, A., Hyttel, P., Odermarsky, M., Liuba, P., Saukko, P., Hansen, Axel Kornerup & Pesonen, E., 2013, In: Journal of Cardiovascular Translational Research. 6, 4, p. 579-587 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Evaluation of the breeding program aiming at reducing the prevalence of myxomatous mitral valve disease in Cavalier King Charles Spaniels in Denmark

    Birkegaard , A. C., Reimann, Maria Josefine, Häggström, J., Martinussen, Torben, Pedersen , H. D. & Olsen, Lisbeth Høier, 2013, American College of Veterinary Internal Medicine, Congress Proceedings. Sellon, R. K. & McClure, J. T. (eds.). Lakewood, p. 172 1 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  50. Published

    Expression of immune relevant genes in rainbow trout following exposure to live Anisakis simplex larvae

    Haarder, S., Kania, Per, Bahlool, Q. Z. M. & Buchmann, Kurt, 2013, In: Experimental Parasitology. 135, 3, p. 564-569 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Guinea pig ascorbate status predicts tetrahydrobiopterin plasma concentration and oxidation ratio in vivo

    Mortensen, A., Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrition Research. 33, 10, p. 859-867 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Gut microbiota regulates NKG2D ligand expression on intestinal epithelial cells

    Hansen, Camilla Hartmann Friis, Holm, T. L., Krych, Lukasz, Andresen, Lars, Nielsen, Dennis Sandris, Rune, Ida, Hansen, Axel Kornerup & Skov, Søren, 2013, In: European Journal of Immunology. 43, 2, p. 447-457 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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