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  1. 2015
  2. Published

    Piroxicam treatment augments bone abnormalities in interleukin-10 knockout mice

    Holgersen, Kristine, Dobie, R., Farquharson, C., Van't Hof, R., Ahmed, S. F., Hansen, Axel Kornerup & Lindebo Holm, T., Feb 2015, In: Inflammatory Bowel Diseases. 21, 2, p. 257-266 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    In vivo toxicity of cationic micelles and liposomes

    Knudsen, K. B., Northeved, H., Kumar Ek, P., Permin, A., Gjetting, T., Andresen, T. L., Larsen, S., Wegener, K. M., Lykkesfeldt, Jens, Jantzen, K., Loft, Steffen, Møller, Peter & Roursgaard, Martin, 25 Feb 2015, In: Nanomedicine: Nanotechnology, Biology and Medicine. 11, 2, p. 467-477 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    High-resolution gene expression profiling using RNA sequencing in patients with inflammatory bowel disease and in mouse models of colitis

    Holgersen, Kristine, Kutlu, B., Fox, B., Serikawa, K., Lord, J., Hansen, Axel Kornerup & Holm, T. L., Mar 2015, In: Journal of Crohn's and Colitis (JCC). 9, 6, p. 492-506 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study

    Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Alpha-smooth muscle actin and serotonin receptors 2A and 2B in dogs with myxomatous mitral valve disease

    Cremer, Signe Emilie, Moesgaard, S. G., Rasmussen, C. E., Zois, N. E., Falk, T., Reimann, Maria Josefine, Cirera, Susanna, Aupperle, H., Oyama, M. A. & Olsen, Lisbeth Høier, 19 Mar 2015, In: Research in Veterinary Science. 100, p. 197-206 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Lower limb ischaemia and reperfusion injury in healthy volunteers measured by oxidative and inflammatory biomarkers

    Halladin, N. L., Busch, S. V. E., Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 10 Apr 2015, In: Perfusion. 30, 1, p. 64-70 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The Zebra Fish IBD Model Assessed By Novel Probe Based TagMan Assays

    Kania, Per, Buchmann, Kurt & Haarder, S., 29 Jun 2015.

    Research output: Contribution to conference › Conference abstract for conference › Research

  9. Published

    Antimicrobial drug penetration into the pulmonary epithelial lining fluid and muscle measured by microdialysis in anesthetized pigs

    Rottbøll, Lisa Amanda Holm & Friis, C., Jul 2015, In: Journal of Veterinary Pharmacology and Therapeutics. 38, S1, p. 89 1 p., 1.12.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  10. Published

    Chronic dyslipidemia induces fatty liver disease in Guinea pigs

    Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland & Lykkesfeldt, Jens, Jul 2015, In: Atherosclerosis. 241, 1, p. e119-e120 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  11. Published

    Vascular gene expression in diet-induced atherosclerotic Gottingen minipigs

    Christensen, Liv von Voss, Skovgaard, K., Ludvigsen, T. P., Kirk, R. K., Christoffersen, B. O., Pedersen, H. D., Heegaard, P. M. & Olsen, Lisbeth Høier, Jul 2015, In: Atherosclerosis. 241, 1, p. E85-E85 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  12. Published

    Calcium signaling in coronary artery after reperfusion damage in rat model of acute myocardial infarct

    Kristiansen, S. B., Skovsted, Gry Freja, Sheykhzade, Majid & Edvinsson, L., Sep 2015, In: Acta Physiologica (Print). 215, Supplement, p. 3-4 7.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  13. Published

    Thick methacrylate sections devoid of lost caps simplify stereological quantifications based on the optical fractionator design

    Andersen, S. H., Lykkesfeldt, Jens & Larsen, J. O., 15 Sep 2015, In: Anatomical Record. 298, 12, p. 2141-2150 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Treatment with anti-C5aR mAb leads to early-onset clinical and mechanistic effects in the murine delayed-type hypersensitivity arthritis model

    Atkinson, S. M., Nansen, A., Usher, P. A., Sondergaard, B., Mackay, C. R., Friedrichsen, B., Chang, C., Tang, R., Skov, Søren, Haase, C. & Hornum, L., Nov 2015, In: Autoimmunity. 48, 7, p. 460-470 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. 2016
  16. Published

    L-dehydroascorbic acid can substitute L-ascorbic acid as dietary vitamin C source in guinea pigs

    Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Redox Biology. 7, p. 8-13 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Breeding Restrictions Decrease the Prevalence of Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels over an 8-to 10-Year Period

    Birkegård, A. C., Reimann, Maria Josefine, Martinussen, Torben, Haggstrom, J., Pedersen, H. D. & Olsen, Lisbeth Høier, 2016, In: Journal of Veterinary Internal Medicine. 30, 1, p. 63-68 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Depletion of regulatory T cells leads to an exacerbation of delayedtype hypersensitivity arthritis in C57BL/6 mice that can be counteracted by IL-17 blockade

    Atkinson, S. M., Hoffmann, U., Bach, E., Danneskiold-Samsøe, Niels Banhos, Kristiansen, Karsten, Serikawa, K., Fox, B., Kruse, K., Haase, C., Skov, Søren & Nansen, A., 2016, In: Disease Models & Mechanisms. 9, p. 427-440 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Does Glucagon-like Peptide-1 Ameliorate Oxidative Stress in Diabetes? Evidence Based on Experimental and Clinical Studies

    Petersen, Karen Ekkelund, Rakipovski, G., Raun, K. & Lykkesfeldt, Jens, 2016, In: Current Diabetes Reviews. 12, 4, p. 331-358 28 p.

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    Gall midges (Diptera: Cecidomyiidae) new to the Danish fauna

    Haarder, S., Bruun, Hans Henrik, Harris, K. M. & Skuhravá, M., 2016, In: Entomologisk Tidskrift. 137, p. 79-98 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    High-fat but not sucrose intake is essential for induction of dyslipidemia and non-alcoholic steatohepatitis in guinea pigs

    Ipsen, David Højland, Tveden-Nyborg, Pernille, Rolin, B., Rakipovski, G., Beck, M., Mortensen, L. W., Færk, L., Heegaard, P. M. H., Møller, Peter & Lykkesfeldt, Jens, 2016, In: Nutrition & Metabolism. 13, p. 51

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Modulating the gut microbiota improves glucose tolerance, lipoprotein profile and atherosclerotic plaque development in ApoE-deficient mice

    Rune, Ida, Rolin, B., Larsen, C. S., Nielsen, Dennis Sandris, Kanter, J. E., Bornfeldt, K. E., Lykkesfeldt, Jens, Buschard, K., Kirk, R. K., Christoffersen, B., Fels, J. J., Josefsen, K., Kihl, Pernille & Hansen, Axel Kornerup, 2016, In: P L o S One. 11, 1, 16 p., e0146439.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Penetration of antimicrobials to pulmonary epithelial lining fluid and muscle and impact of drug physicochemical properties determined by microdialysis

    Rottbøll, Lisa Amanda Holm & Friis, C., 2016, In: Journal of Pharmacological and Toxicological Methods. 78, p. 58-65 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Simvastatin and oxidative stress in humans: A randomized, double-blinded, placebo-controlled clinical trial

    Rasmussen, S. T., Andersen, Jon Thor Trærup, Nielsen, T. K., Cejvanovic, V., Petersen, K. M., Henriksen, T., Weimann, A., Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2016, In: Redox Biology. 9, p. 32-38

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Spontaneous bleeds in the elbows of F8-/- rats cause development of blood-induced joint disease closely resembling human hemophilic arthropathy

    Thyme, A. P., Vøls, Kåre Kryger, Christensen, K. R., Löfgren, Karin Maria, Wiinberg, B., Kvist, P. H., Kjelgaard-Hansen, M., Roepstorff, K., Nielsen, Lise Nikolic & Tranholm, M., 2016.

    Research output: Contribution to conference › Conference abstract for conference › Research

  26. Published

    Vitaminer til hjernen

    Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Aktuel Naturvidenskab. 2016, 4, p. 8-11 4 p.

    Research output: Contribution to journal › Journal article › Research

  27. Published

    Histopathological nerve and skeletal muscle changes in rats subjected to persistent insulin-induced hypoglycemia

    Jensen, Vivi Flou Hjorth, Mølck, A., Heydenreich, A., Jensen, K. J., Bertelsen, L. O., Alifrangis, L., Andersen, L., Søeborg, H., Chapman, M., Lykkesfeldt, Jens & Bøgh, I. B., Jan 2016, In: Toxicologic Pathology. 29, 1, p. 17-30 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Pulsatile Hyperglycaemia Induces Vascular Oxidative Stress and GLUT 1 Expression More Potently than Sustained Hyperglycaemia in Rats on High Fat Diet

    Rakipovski, G., Lykkesfeldt, Jens & Raun, K., 20 Jan 2016, In: P L o S One. 11, 1, e0147412.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Anti-RANKL treatment inhibits erosive joint destruction and lowers inflammation but has no effect on bone formation in the delayed-type hypersensitivity arthritis (DTHA) model

    Atkinson, S. M., Bleil, J., Maier, R., Kuehl, A. A., Thorn, M., Serikawa, K., Fox, B., Kruse, K., Haase, C., Skov, Søren, Nansen, A. & Syrbe, U., 23 Jan 2016, In: Arthritis Research & Therapy. 18, 12 p., 28.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Zebrafisken - en holistisk miljømodel

    Buchmann, Kurt, Kania, Per, Haarder, S. & Jørgensen, Louise von Gersdorff, 25 Jan 2016, Villum Fonden - Velux Fonden: årsskrift 2015. Søborg: Villum Fonden, p. 52-58 7 p. (Villum Fonden - Velux Fonden : årsskrift, Vol. 2015).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  31. Published

    Similar Adiponectin Levels in Obese Normotensive and Obese Hypertensive Men and No Vasorelaxant Effect of Adiponectin on Human Arteries

    Dreier, R., Asferg, C., Berg, J. O., Andersen, U. B., Flyvbjerg, A., Frystyk, J., Linneberg, Allan René, Jeppesen, J. L., Edvinsson, L. & Skovsted, Gry Freja, Feb 2016, In: Basic & Clinical Pharmacology & Toxicology. 118, 2, p. 128–135 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Diet-induced dyslipidemia leads to nonalcoholic fatty liver disease and oxidative stress in guinea pigs

    Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland, Thiessen, T. S., Feldmann, L. D. B., Lindblad, M. M., Jensen, Henrik Elvang & Lykkesfeldt, Jens, 1 Feb 2016, In: Translational Research. 168, p. 146-160 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Increased serum C-reactive protein concentrations in dogs with congestive heart failure due to myxomatous mitral valve disease

    Reimann, Maria Josefine, Ljungvall, I., Hillstrom, A., Møller, J. E., Hagman, R., Falk, T., Hoglund, K., Haggstrom, J. & Olsen, Lisbeth Høier, Mar 2016, In: Veterinary Journal. 209, p. 113-118

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Normal Weight Dyslipidemia: Is It All About the Liver?

    Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Mar 2016, In: Obesity. 24, 3, p. 556-567 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  35. Published

    Antibody response to recombinant human coagulation factor VIII in a new rat model of severe hemophilia A

    Löfgren, Karin Maria, Sondergaard, H., Skov, Søren, Weldingh, K. N., Tranholm, M. & Wiinberg, B., Apr 2016, In: Journal of Thrombosis and Haemostasis. 14, 4, p. 747-756

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    The kidneys play a central role in the clearance of rhGH in rats

    Vestergaard, Bill, Thygesen, P., Kreilgaard, M., Fels, J. J., Lykkesfeldt, Jens & Agerso, H., 30 Apr 2016, In: European Journal of Pharmaceutical Sciences. 86, p. 29-33

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Changes in heart rate, arrhythmia frequency, and cardiac biomarker values in horses during recovery after a long-distance endurance ride

    Madsen, M. F., Kanters, Jørgen K., Haugaard, M. M., Pedersen, P. J., Carstensen, Helena, Balling, J. D., Olsen, Lisbeth Høier & Buhl, Rikke, 1 May 2016, In: Journal of the American Veterinary Medical Association. 248, 9, p. 1034-1042 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Establishment and use of surgical rat models for assessment of organ specific in vivo clearance

    Vestergaard, Bill, Jun 2016, In: Danish Medical Journal. 63, 6, 17 p., B5247.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    Reduced Mechanical Stretch Induces Enhanced Endothelin B Receptor-mediated Contractility via Activation of Focal Adhesion Kinase and Extra Cellular-regulated Kinase 1/2 in Cerebral Arteries from Rat

    Spray, S., Rasmussen, M. N. P., Skovsted, Gry Freja, Warfvinge, K., Sheykhzade, Majid & Edvinsson, L., Jun 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 1, p. 68-77 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    The F8(-/-) rat as a model of hemophilic arthropathy

    Christensen, K. R., Roepstorff, K., Wiinberg, B., Hansen, Axel Kornerup, Tranholm, M., Nielsen, Lise Nikolic & Kjelgaard-Hansen, M., Jun 2016, In: Journal of Thrombosis and Haemostasis. 14, 6, p. 1216-1225 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes

    Flethøj, M., Schwarzwald, C. C., Haugaard, M. M., Carstensen, Helena, Kanters, Jørgen K., Olsen, Lisbeth Høier & Buhl, Rikke, Jul 2016, In: Journal of Veterinary Internal Medicine. 30, 4, p. 1260-1269 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Maternal vitamin C deficiency does not reduce hippocampal volume and beta-tubulin III intensity in prenatal Guinea pigs

    Hansen, S. N., Schjoldager, J. G., Paidi, M. D., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, Jul 2016, In: Nutrition Research. 36, 7, p. 696-702

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Strategies for Using Plagiarism Software in the Screening of Incoming Journal Manuscripts: Recommendations Based on a Recent Literature Survey

    Lykkesfeldt, Jens, Aug 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 2, p. 161-164

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Rodent model choice has major impact on variability of standard preclinical readouts associated with diabetes and obesity research

    Jensen, Victoria Svop, Porsgaard, T., Lykkesfeldt, Jens & Hvid, H., 15 Aug 2016, In: American Journal of Translational Research. 8, 8, p. 3574-3584

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Simultaneous quantification of monoamine neurotransmitters and their biogenic metabolites intracellularly and extracellularly in primary neuronal cell cultures and in sub-regions of guinea pig brain

    Schou-Pedersen, A. M. V., Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 15 Aug 2016, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1028, p. 222-230 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Joint bleeds increase the inhibitor response to human factor VIII in a rat model of severe haemophilia A

    Löfgren, Karin Maria, Søndergaard, H., Skov, Søren & Wiinberg, B., Sep 2016, In: Haemophilia. 22, 5, p. 772-779 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Non-genetic risk factors in haemophilia A inhibitor management: the danger theory and the use of animal models

    Löfgren, Karin Maria, Søndergaard, H., Skov, Søren & Wiinberg, B., Sep 2016, In: Haemophilia. 22, 5, p. 657-666 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice

    Christophersen, D. V., Raun Jacobsen, N., Guerra Andersen, M. H., Connell, S. P., Barfod, K. K., Thomsen, Morten Bækgaard, Miller, M. R., Duffin, R., Lykkesfeldt, Jens, Vogel, U. B., Wallin, E. H. R., Loft, Steffen, Roursgaard, Martin & Møller, Peter, 14 Sep 2016, In: Toxicology. 371, p. 29-40 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Long-term excess fat and/or fructose ingestion causes changes in small artery K+ transporter expression and function with effects on blood pressure

    Gradel, Anna Katrina Jógvansdóttir, Salomonsson, M., Sorensen, Charlotte Mehlin, von Holstein-Rathlou, Niels-Henrik & Jensen, Lars Jørn, 22 Sep 2016. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  50. Published

    In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines

    Roursgaard, Martin, Knudsen, K. B., Northeved, H., Persson, M., Christensen, T., Kumar, P. E. K., Permin, A., Andresen, T. L., Gjetting, T., Lykkesfeldt, Jens, Vesterdal, L. K., Loft, Steffen & Møller, Peter, Oct 2016, In: Toxicology in Vitro. 36, p. 164-171 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Is Diabetes Associated with Lower Vitamin C Status in Pregnant Women? A Prospective Study

    Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, Oct 2016, In: International Journal for Vitamin and Nutrition Research. 86, 5-6, p. 184-189

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Oxidative costs of reproduction in mouse strains selected for different levels of food intake and which differ in reproductive performance

    Jothery, A. H. A., Vaanholt, L. M., Mody, N., Arnous, A., Lykkesfeldt, Jens, Bunger, L., Hill, W. G., Mitchell, S. E., Allison, D. B. & Speakman, J. R., 14 Nov 2016, In: Scientific Reports. 6, 12 p., 36353 .

    Research output: Contribution to journal › Journal article › Research › peer-review

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