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  1. Published

    In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines

    Roursgaard, Martin, Knudsen, K. B., Northeved, H., Persson, M., Christensen, T., Kumar, P. E. K., Permin, A., Andresen, T. L., Gjetting, T., Lykkesfeldt, Jens, Vesterdal, L. K., Loft, Steffen & Møller, Peter, Oct 2016, In: Toxicology in Vitro. 36, p. 164-171 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    In vivo effect of rFVIII and rFVIIa in hemophilia A rats evaluated by the Tail Vein Transection Bleeding Model

    Stagaard, Rikke, Øvlisen, Gabi Overgaard, Klæbel, J. H., Danielsen, D., Lund, A., Elm, T. & Ley, C. D., 2023, In: Journal of Thrombosis and Haemostasis. 21, 5, p. 1189-1199 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    L-dehydroascorbic acid can substitute L-ascorbic acid as dietary vitamin C source in guinea pigs

    Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Redox Biology. 7, p. 8-13 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    18F-FDG PET/MR-imaging in a Göttingen Minipig model of atherosclerosis: Correlations with histology and quantitative gene expression

    Ludvigsen, T. P., Pedersen, S. F., Vegge, A., Ripa, Rasmus Sejersten, Johannesen, H. H., Hansen, Adam Espe, Löfgren, J., Schumacher-Petersen, Camilla, Kirk, R. K., Pedersen, H. D., Christoffersen, B. Ø., Ørbæk, M., Forman, Julie Lyng, Klausen, T. L., Olsen, Lisbeth Høier & Kjær, Andreas, 2019, In: Atherosclerosis. 285, p. 55-63 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    35Sulphate incorporation assay as a new tool for measuring early cartilage degradation following blood exposure in vitro and in vivo in f8 ko rats

    Pulles, A. E., Christensen, K. R., Coeleveld, K., Kjelgaard-Hansen, M., Schutgens, R. E., Lafeber, F. P., Roepstorff, K. & Mastbergen, S. C., Apr 2017, In: Osteoarthritis and Cartilage. 25, S1, p. S156-S157

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  6. Published

    A cafeteria diet alters the decision making strategy and metabolic markers in Sprague-Dawley male rats

    Virtuoso, Alessandro, Forkman, Björn, Sarruf, D. A., Tveden-Nyborg, Pernille & Sørensen, Dorte Bratbo, 2018, In: Applied Animal Behaviour Science. 199, p. 35-44 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A long‐term energy‐rich diet increases prefrontal bdnf in sprague‐dawley rats

    Virtuoso, Alessandro, Tveden-Nyborg, Pernille, Schou‐pedersen, A. M. V., Lykkesfeldt, Jens, Müller, H. K., Elfving, B. & Sørensen, Dorte Bratbo, 2022, In: Nutrients. 14, 1, 126.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A porcine model of subcutaneous Staphylococcus aureus infection: a pilot study

    Nielsen, O. L., Mellergaard, M., Frees, Dorte, Larsen, M. N., Skov, Søren, Olsen, Lisbeth Høier & Reimann, Maria Josefine, 2022, In: APMIS - Journal of Pathology, Microbiology and Immunology. 130, 7, p. 359-370

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A porcine subcutaneous Staphylococcus aureus abscess model - a pilot study

    Nielsen, O. L., Larsen, M. N., Frees, Dorte, Pedersen, M. M., Skov, Søren & Olsen, Lisbeth Høier, 2017.

    Research output: Contribution to conference › Conference abstract for conference › Communication

  10. Published

    A role of peroxisome proliferator-activated receptor gamma in non-alcoholic fatty liver disease

    Skat-Rørdam, Josephine, Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, May 2019, In: Basic & Clinical Pharmacology & Toxicology. 124, 5, p. 528-537

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate®)

    Pastoft, A. E., Lykkesfeldt, Jens, Ezban, M., Tranholm, M., Whinna, H. C. & Lauritzen, B., 2012, In: Haemophilia. 18, 5, p. 782-788 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A systematic Cochrane Review of antioxidant supplementation lung disease for cystic fibrosis

    Ciofu, Oana, Smith, S. & Lykkesfeldt, Jens, 2020, In: Paediatric Respiratory Reviews. 33, p. 28-29

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  13. Published

    Abrogating fibrinolysis does not improve bleeding or rFVIIa/rFVIII treatment in a non-mucosal venous injury model in haemophilic rodents

    Stagaard, R., Flick, M. J., Bojko, B., Goryński, K., Goryńska, P. Z., Ley, C. D., Olsen, Lisbeth Høier & Knudsen, T., 2018, In: Journal of Thrombosis and Haemostasis. 16, 7, p. 1369-1382 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Absence of functional compensation between coagulation factor VIII and plasminogen in double-knockout mice

    Stagaard, R., Ley, C. D., Almholt, K., Olsen, Lisbeth Høier, Knudsen, T. & Flick, M. J., 2018, In: Blood advances. 2, 22, p. 3126-3136 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Activation of the renal GLP-1R leads to expression of Ren1 in the renal vascular tree

    Bjørnholm, K. D., Ougaard, M. E., Skovsted, Gry Freja, Knudsen, L. B. & Pyke, C., 2021, In: Endocrinology, Diabetes and Metabolism. 4, 3, e00234.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Acute Haemarthrosis in the Haemophilia A Rat Generates a Local and Systemic Proinflammatory Response

    Lovgren, K. M., Christensen, K. R., Majewski, W., Ostrup, O., Skov, Søren & Wiinberg, B., Nov 2017, In: Thrombosis and Haemostasis. 117, 11, p. 2092-2104

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Advanced electrocardiographic parameters change with severity of mitral regurgitation in Cavalier King Charles Spaniels in sinus rhythm

    Pakkanen, M. S., Petric, A. D., Olsen, Lisbeth Høier, Stepancic, A., Schlegel, T. T., Falk, B. T., Rasmussen, C. E. & Starc, V., 2012, In: Journal of Veterinary Internal Medicine. 26, 1, p. 93-100 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Advances in targeted delivery of small interfering RNA using simple bioconjugates

    Nielsen, C., Kjems, J., Sørensen, K. R., Engelholm, Lars Henning & Behrendt, Niels, 2014, In: Expert Opinion on Drug Delivery. 11, 5, p. 791-822 32 p.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Alpha-smooth muscle actin and serotonin receptors 2A and 2B in dogs with myxomatous mitral valve disease

    Cremer, Signe Emilie, Moesgaard, S. G., Rasmussen, C. E., Zois, N. E., Falk, T., Reimann, Maria Josefine, Cirera, Susanna, Aupperle, H., Oyama, M. A. & Olsen, Lisbeth Høier, 19 Mar 2015, In: Research in Veterinary Science. 100, p. 197-206 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Ampicillin-improved glucose tolerance in diet-induced obese C57BL/6NTac mice is age dependent

    Rune, Ida, Hansen, Camilla Hartmann Friis, Ellekilde, M., Nielsen, Dennis Sandris, Skovgaard, K., Rolin, B. C., Lykkesfeldt, Jens, Josefsen, K., Christensen, B. T., Kihl, Pernille & Hansen, Axel Kornerup, 2013, In: Experimental Diabetes Research. 2013, 13 p., 319321.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    An ELISA for detection of complement-bound circulating immune complexes in mice

    Boysen, L., Lauritzen, B., Viuff, B. M., Lykkesfeldt, Jens & Landsy, L. H., 2019, In: Journal of Immunotoxicology. 16, 1, p. 82-86 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    An Early Life Mucosal Insult Temporarily Decreases Acute Oxazolone-Induced Inflammation in Mice

    Bendtsen, K. M., Tougaard, P. & Hansen, Axel Kornerup, 2018, In: Inflammation. 41, 4, p. 1437-1447 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    An Oligosaccharide Rich Diet Increases Akkermansia spp. Bacteria in the Equine Microbiota

    Lindenberg, F. C., Lützhøft, Ditte Olsen, Krych, Lukasz, Fielden, J., Kot, Witold, Frøkiær, Hanne, van Galen, G., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2021, In: Frontiers in Microbiology. 12, 666039.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    An improved method for lifting and transporting anesthetized pigs within an animal facility

    Schumacher-Petersen, Camilla, Hammelev, Karsten Pharao & Flescher, Jens, Jul 2014, In: Lab Animal. 43, 7, p. 237-41 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    An oxazolone zebrafish model for inflammatory bowel disease (IBD): preliminary results

    Haarder, S., Kania, Per, Hyttel, P., Lindebo Holm, T. & Buchmann, Kurt, 2014.

    Research output: Contribution to conference › Poster › Research › peer-review

  26. Published

    Analytical validation of a conventional cardiac troponin I assay for dogs and cats

    Langhorn, Rebecca, Yrfelt, J. D., Stjernegaard, C. S., Christiansen, L. B., Olsen, Lisbeth Høier & Nielsen, Lise Nikolic, 2019, In: Veterinary Clinical Pathology. p. 36-41

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Analytical validation of a flow cytometric protocol for quantification of platelet microparticles in dogs

    Cremer, Signe Emilie, Krogh, Anne Kirstine Havnsøe, Hedström, M. E. K., Christiansen, L. B., Tarnow, I. & Kristensen, Annemarie T., Jun 2018, In: Veterinary Clinical Pathology. 47, 2, p. 186-196 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Angiotensin-converting enzyme activity in Cavalier King Charles Spaniels with an ACE gene polymorphism and myxomatous mitral valve disease

    Meurs, K. M., Olsen, Lisbeth Høier, Reimann, Maria Josefine, Keene, B. W., Atkins, C. E., Adin, D., Aona, B., Condit, J., Defrancesco, T., Reina-Doreste, Y., Stern, J. A., Tou, S., Ward, J. & Woodruff, K., 2018, In: Pharmacogenetics and Genomics. 28, 2, p. 37-40 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Animal Models of Fibrosis in Nonalcoholic Steatohepatitis: Do They Reflect Human Disease?

    Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2020, In: Advances in Nutrition. 11, 6, p. 1696–1711

    Research output: Contribution to journal › Review › Research › peer-review

  30. Published

    Animal models in pharmacology and toxicology

    Meyer, O. A., Svendsen, O. & Lykkesfeldt, Jens, 2011, Handbook of laboratory animal science: volume II: Animal models. Hau, J. & J. Schapiro, S. (eds.). 3. ed. ed. CRC Press, Vol. 2. p. 149-184 36 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  31. Published

    Anti-RANKL treatment inhibits erosive joint destruction and lowers inflammation but has no effect on bone formation in the delayed-type hypersensitivity arthritis (DTHA) model

    Atkinson, S. M., Bleil, J., Maier, R., Kuehl, A. A., Thorn, M., Serikawa, K., Fox, B., Kruse, K., Haase, C., Skov, Søren, Nansen, A. & Syrbe, U., 23 Jan 2016, In: Arthritis Research & Therapy. 18, 12 p., 28.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Antibody response to recombinant human coagulation factor VIII in a new rat model of severe hemophilia A

    Löfgren, Karin Maria, Sondergaard, H., Skov, Søren, Weldingh, K. N., Tranholm, M. & Wiinberg, B., Apr 2016, In: Journal of Thrombosis and Haemostasis. 14, 4, p. 747-756

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Antimicrobial drug penetration into the pulmonary epithelial lining fluid and muscle measured by microdialysis in anesthetized pigs

    Rottbøll, Lisa Amanda Holm & Friis, C., Jul 2015, In: Journal of Veterinary Pharmacology and Therapeutics. 38, S1, p. 89 1 p., 1.12.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  34. Published

    Antioxidant supplementation does not alter endurance training adaptation

    Yfanti, C., Åkerström, T., Nielsen, S., Nielsen, A. R., Mounier, R., Mortensen, Ole Hartvig, Lykkesfeldt, Jens, Rose, A. J., Fischer, C. P. & Pedersen, Bente Klarlund, 1 Jul 2010, In: Medicine and Science in Sports and Exercise. 42, 7, p. 1388-95 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Antioxidant supplementation for lung disease in cystic fibrosis

    Ciofu, Oana & Lykkesfeldt, Jens, 2014, In: The Cochrane library. 2014, 8, 87 p., CD007020.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Antioxidant supplementation for lung disease in cystic fibrosis

    Ciofu, Oana, Smith, S. & Lykkesfeldt, Jens, 2019, In: Cochrane Database of Systematic Reviews. 2019, 10, CD007020.

    Research output: Contribution to journal › Review › Research › peer-review

  37. Published

    Applicability of chronic inflammation models for mechanistic in vivo studies

    Christensen, A. D., 2014

    Research output: Book/Report › Ph.D. thesis › Research

  38. Published

    Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings

    Madsen, M. F., Kanters, Jørgen K., Pedersen, P. J., Haugaard, M. M., Carstensen, Helena, Olsen, Lisbeth Høier & Buhl, Rikke, 28 Nov 2016, In: BMC Veterinary Research. 12, 10 p., 266.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Ascorbate and dehydroascorbic acid as biomarkers of oxidative stress: validity of clinical data depends on vacutainer system used

    Lykkesfeldt, Jens, 2012, In: Nutrition Research. 32, 1, p. 66-69 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Ascorbate deficiency increases progression of shigellosis in guinea pigs and mice infection models

    Skerniskyte, J., Mulet, C., André, A. C., Anderson, M. C., Injarabian, L., Buck, A., Prade, V. M., Sansonetti, P. J., Reibel-Foisset, S., Walch, A. K., Lebel, M., Lykkesfeldt, Jens & Marteyn, B. S., 2023, In: Gut Microbes. 15, 2, 18 p., 2271597.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Ascorbate maintains a low plasma oxygen level

    Injarabian, L., Scherlinger, M., Devin, A., Ransac, S., Lykkesfeldt, Jens & Marteyn, B. S., 2020, In: Scientific Reports. 10, 1, 6 p., 10659.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Ascorbate status modulates reticuloendothelial iron stores and response to deferasirox iron chelation in ascorbate-deficient rats

    Brewer, C., Otto-Duessel, M., Lykkesfeldt, Jens, Nick, H. & Wood, J. C., 2012, In: Experimental Hematology. 40, 10, p. 820-827 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Assessment of implantable infusion pumps for continuous infusion of human insulin in rats: potential for group housing

    Jensen, Vivi Flou Hjorth, Molck, A., Martensson, M., Strid, M. A., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: Laboratory Animals. 51, 3, p. 273-283

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Associations between N-terminal procollagen type III, fibrosis and echocardiographic indices in dogs that died due to myxomatous mitral valve disease

    Hezzell, M. J., Falk, B. T., Olsen, Lisbeth Høier, Boswood, A. & Elliott, J., 2014, In: Journal of Veterinary Cardiology. 16, 4, p. 257-264 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Asymmetric dimethylarginine in somatically healthy schizophrenia patients treated with atypical antipsychotics: a case-control study

    Jørgensen, Anders, Knorr, Ulla Benedichte Søsted, Soendergaard, M. G., Lykkesfeldt, Jens, Fink-Jensen, Anders, Poulsen, Henrik Enghusen, Jørgensen, Martin Balslev, Olsen, N. V. & Staalsø, J. M., 2015, In: B M C Psychiatry. 15, 8 p., 67.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Atorvastatin and vitamin e accelerates NASH resolution by dietary intervention in a preclinical guinea pig model

    Klaebel, J. H., Skjødt, M., Skat-Rørdam, Josephine, Rakipovski, G., Ipsen, David Højland, Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 11, 20 p., 2834.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected

    Christiansen, L. B., Dohlmann, T. L., Ludvigsen, T. P., Parfieniuk, E., Ciborowski, M., Szczerbinski, L., Kretowski, A., Desler, Claus, Tiano, L., Orlando, P., Martinussen, Torben, Olsen, Lisbeth Høier & Larsen, Steen, 2021, In: Scientific Reports. 11, 15 p., 2167.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    BCPT 2023 policy for experimental and clinical studies

    Tveden-Nyborg, Pernille, Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, Jens, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 4, p. 391-396

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    BCPT policy for experimental and clinical studies

    Tveden-Nyborg, Pernille, Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, Jens, 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 4-8

    Research output: Contribution to journal › Review › Research › peer-review

  50. Published

    Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies

    Tveden-Nyborg, Pernille, Bergmann, T. K. & Lykkesfeldt, Jens, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 233-235 3 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

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