- 2023
- Published
BCPT 2023 policy for experimental and clinical studies
Tveden-Nyborg, Pernille, Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, Jens, 2023, In: Basic and Clinical Pharmacology and Toxicology. 133, 4, p. 391-396Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intestinal permeability marker FITC-dextran 4kDa should be dosed according to lean body mass in obese mice
Voetmann, Louise Marie, Rolin, B., Kirk, R. K., Pyke, C. & Hansen, Axel Kornerup, 2023, In: Nutrition and Diabetes. 13, 1.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Remote Ischaemic Preconditioning on Perioperative Endothelial Dysfunction in Non-Cardiac Surgery: A Randomised Clinical Trial
Wahlstrøm, K. L., Hansen, H. F., Kvist, M., Burcharth, Jakob, Lykkesfeldt, Jens, Gögenur, Ismail & Ekeloef, S., 2023, In: Cells. 12, 6, 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes
Callø, Kirstine, Geryk, M., Freude, Kristine, Treat, J. A., Vold, V. A., Frederiksen, Henriette Reventlow S, Broendberg, A. K., Frederiksen, T. C., Jensen, H. K. & Cordeiro, J. M., 2022, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 24, 12, p. 2015–2027Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implantation of telemetric blood pressure transmitters in Göttingen Minipigs: Validation of 24-h systemic blood pressure and heart rate monitoring and influence of anaesthesia
Carlsen, M. F., Christoffersen, B. Ø., Lindgaard, R., Pedersen, H. D. & Olsen, Lisbeth Høier, 2022, In: Journal of Pharmacological and Toxicological Methods. 115, 107168.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Estimation of Vitamin C Intake Requirements Based on Body Weight: Implications for Obesity
Carr, A. C., Block, G. & Lykkesfeldt, Jens, 2022, In: Nutrients. 14, 7, 8 p., 1460.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Semaglutide treatment attenuates vessel remodelling in ApoE−/− mice following vascular injury and blood flow perturbation
Jensen, Ditte Marie, Skovsted, Gry Freja, Bonde, M. F. B., Bentzon, J. F., Rolin, B., Franck, G., Ougaard, M. K. E., Voetmann, Louise Marie, Bachmann, J. C., Uryga, A., Pyke, C., Kirk, R. K., Hvid, H., Knudsen, L. B., Lykkesfeldt, Jens & Nyberg, M., 2022, In: Atherosclerosis Plus. 49, p. 32-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prolonged insulin-induced hypoglycaemia reduces ß-cell activity rather than number in pancreatic islets in non-diabetic rats
Jensen, Vivi Flou Hjorth, Mølck, A. M., Nowak, J., Fels, J. J., Lykkesfeldt, Jens & Bøgh, I. B., 2022, In: Scientific Reports. 12, 14113.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of gluten-free diet and antibiotics on murine gut microbiota and immune response to tetanus vaccination
Kihl, Pernille, Krych, Lukasz, Deng, Ling, Hansen, Lars Hestbjerg, Buschard, K., Skov, Søren, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: Plos One. 17, 4, 21 p., e0266719.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy of fibroblast growth factor 21 in non-alcoholic fatty liver disease in guinea pigs
Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Basic & Clinical Pharmacology & Toxicology. 130, 3, p. 385-393Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electrocardiography and heart rate variability in Göttingen Minipigs: Impact of diurnal variation, lead placement, repeatability and streptozotocin-induced diabetes
Lyhne, Mille Kronborg, Debes, Karina Poulsdóttir, Helgogaard, T., Vegge, A., Kildegaard, J., Pedersen-Bjergaard, Ulrik & Olsen, Lisbeth Høier, 2022, In: Journal of Pharmacological and Toxicological Methods. 118, 107221.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model
Lützhøft, Ditte Olsen, Sinioja, T., Christoffersen, B., Jakobsen, Rasmus Riemer, Geng, Dawei, Ahmad, H. F. B., Straarup, E. M., Pedersen, K. M., Kot, Witold, Pedersen, H. D., Cirera, Susanna, Hyötyläinen, T., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: BMC Microbiology. 22, 1, 287.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lower Vitamin C Levels Are Associated With Less Improvement in Negative Symptoms in Initially Antipsychotic-Naïve Patients With First-Episode Psychosis
Myken, A. N., Ebdrup, Bjørn, Sørensen, M. E., Broberg, B. V., Skjerbæk, M. W., Glenthøj, Birte Yding, Lykkesfeldt, Jens & Nielsen, Mette Ødegaard, 2022, In: The international journal of neuropsychopharmacology. 25, 8, p. 613-618 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A porcine model of subcutaneous Staphylococcus aureus infection: a pilot study
Nielsen, O. L., Mellergaard, M., Frees, Dorte, Larsen, M. N., Skov, Søren, Olsen, Lisbeth Høier & Reimann, Maria Josefine, 2022, In: APMIS - Journal of Pathology, Microbiology and Immunology. 130, 7, p. 359-370Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs
Pedersen, Kamilla, Kruhøffer, L. L., Lykkesfeldt, Jens & Kousholt, B. S., 2022, In: Acta Veterinaria Scandinavica. 64, 38.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimization of pig models for translation of subcutaneous pharmacokinetics of therapeutic proteins: Liraglutide, insulin aspart and insulin detemir
Pedersen, K., Gradel, Anna Katrina Jógvansdóttir, Ludvigsen, T. P., Christoffersen, B. Ø., Fuglsang-Damgaard, C. A., Bendtsen, K. M., Madsen, S. H., Manfé, V. & Refsgaard, H. H. F., 2022, In: Translational Research. 239, p. 71-84Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin C deficiency may delay diet-induced NASH regression in the guinea pig
Skat-Rørdam, Josephine, Pedersen, Kamilla, Skovsted, Gry Freja, Gregersen, I., Vangsgaard, S., Ipsen, David Højland, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Antioxidants. 11, 1, 69.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vitamin C Deficiency Exacerbates Dysfunction of Atherosclerotic Coronary Arteries in Guinea Pigs Fed a High-Fat Diet
Skovsted, Gry Freja, Skat-Rørdam, Josephine, Frøkiær, A. P., Jensen, Henrik Elvang, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2022, In: Antioxidants. 11, 11, 2226.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of the sodium-glucose cotransporter-2 inhibitor dapagliflozinon platelet aggregation response in Cavalier King Charles Spanielswith and without cardiac disease
Speitzer, A., Øgelund, E., Reimann, Maria Josefine, Møller, J. E., Skovsted, G. F., Lyhne, Mille Kronborg, Verma, S., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2022, In: Journal of Veterinary Internal Medicine. 36, 6, p. 2473 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
A long‐term energy‐rich diet increases prefrontal bdnf in sprague‐dawley rats
Virtuoso, Alessandro, Tveden-Nyborg, Pernille, Schou‐pedersen, A. M. V., Lykkesfeldt, Jens, Müller, H. K., Elfving, B. & Sørensen, Dorte Bratbo, 2022, In: Nutrients. 14, 1, 126.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro cell cultures of Brunner's glands from male mouse to study GLP-1 receptor function
Voetmann, Louise Marie, Underwood, C. R., Rolin, B., Hansen, Axel Kornerup, Kirk, R. K., Pyke, C., Knudsen, L. B. & Frederiksen, K. S., 2022, In: American journal of physiology. Cell physiology. 322, 6, p. C1260-C1269Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CTLA4-Ig prevents development of neutralizing antibody formation after continuous treatment with human FVIII in HA rats
Øvlisen, Gabi Overgaard, Thygesen, P., Weldingh, K. N., Bloem, E., Skov, Søren, Almholt, K., Lövgren, K. M., Ley, C. D. & Holm, T. L., 2022, In: Haemophilia. 28, 4, p. 568-577Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
The genetic consequences of dog breed formation - Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels: [+ correction]
Axelsson, E., Ljungvall, I., Bhoumik, P., Conn, L. B., Muren, E., Ohlsson, Å., Olsen, L. H., Engdahl, K., Hagman, R., Hanson, J., Kryvokhyzha, D., Pettersson, M., Grenet, O., Moggs, J., Del Rio-Espinola, A., Epe, C., Taillon, B., Tawari, N., Mane, S., Hawkins, T. & 4 others, , 2021, In: PLOS Genetics. 17, 9, 34 p., e1009726.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
[68Ga]Ga-NODAGA-E[(cRGDyK)]2 Angiogenesis PET/MR in a Porcine Model of Chronic Myocardial Infarction
Bentsen, Simon, Clemmensen, Andreas Høeg, Loft, Mathias Hougaard, Flethøj, M., Debes, Karina Poulsdóttir, Ludvigsen, Trine Pagh, Larsen, C. B., Kirchhoff, J., Olsen, Lisbeth Høier, Møller, J. E., Andersen, Thomas Lund, Johannesen, Helle Hjorth, Jespersen, Thomas & Kjær, Andreas, 2021, In: Diagnostics. 11, 10, 1807.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of the renal GLP-1R leads to expression of Ren1 in the renal vascular tree
Bjørnholm, K. D., Ougaard, M. E., Skovsted, Gry Freja, Knudsen, L. B. & Pyke, C., 2021, In: Endocrinology, Diabetes and Metabolism. 4, 3, e00234.Research output: Contribution to journal › Journal article › Research › peer-review
Most downloads
-
5883
downloads
Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
5764
downloads
Increased systemic oxidatively generated DNA and RNA damage in schizophrenia
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
4601
downloads
Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
Research output: Contribution to journal › Review › Research › peer-review
Published
Latest publications
Novel traceable CRISPR-Cas9 engineered human embryonic stem cell line (E1C3 + hSEAP + 2xKO + pCD47), has potential to evade immune detection in pigs
Research output: Contribution to journal › Journal article › Research › peer-review
Vitamin C
Research output: Contribution to journal › Journal article › Research › peer-review
Vitamin C
Research output: Contribution to journal › Journal article › Research › peer-review