Lifepharm

  1. 2017
  2. Published

    Pasteurization Procedures for Donor Human Milk Affect Body Growth, Intestinal Structure, and Resistance against Bacterial Infections in Preterm Pigs

    Li, Y., Nguyen, Duc Ninh, de Waard, M., Christensen, Lars, Zhou, P., Jiang, Pingping, Sun, Jing, Bojesen, Anders Miki, Lauridsen, C., Lykkesfeldt, Jens, Dalsgaard, T. K., Bering, S. B. & Sangild, Per Torp, Jun 2017, In: Journal of Nutrition. 147, 6, p. 1121-1130

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Acute Haemarthrosis in the Haemophilia A Rat Generates a Local and Systemic Proinflammatory Response

    Lovgren, K. M., Christensen, K. R., Majewski, W., Ostrup, O., Skov, Søren & Wiinberg, B., Nov 2017, In: Thrombosis and Haemostasis. 117, 11, p. 2092-2104

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers

    Nielsen, C. F., van Putten, S. M., Lund, I. K., Melander, M. C., Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Reckzeh, K., Christensen, K. R., Ingvarsen, S. Z., Gårdsvoll, Henrik, Jensen, K. E., Hamerlik, P., Engelholm, Lars Henning & Behrendt, Niels, 2017, In: OncoTarget. 8, 27, p. 44605-44624 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A porcine subcutaneous Staphylococcus aureus abscess model - a pilot study

    Nielsen, O. L., Larsen, M. N., Frees, Dorte, Pedersen, M. M., Skov, Søren & Olsen, Lisbeth Høier, 2017.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  6. Published

    Weekly ascorbic acid infusion in castration-resistant prostate cancer patients: A single-arm phase II trial

    Nielsen, Torben Kjær, Højgaard, M., Andersen, Jon Thor Trærup, Jørgensen, N. R., Zerahn, B., Kristensen, B., Henriksen, T., Lykkesfeldt, Jens, Mikines, K. J. & Poulsen, Henrik Enghusen, 2017, In: Translational Andrology and Urology. 6, 3, p. 517-528 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Plasma lipid oxidation predicts atherosclerotic status better than cholesterol in diabetic apolipoprotein E deficient mice

    Petersen, Karen Ekkelund, Lykkesfeldt, Jens, Raun, K. & Rakipovski, G., Jan 2017, In: Experimental Biology and Medicine (Maywood). 242, 1, p. 88-91

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    35Sulphate incorporation assay as a new tool for measuring early cartilage degradation following blood exposure in vitro and in vivo in f8 ko rats

    Pulles, A. E., Christensen, K. R., Coeleveld, K., Kjelgaard-Hansen, M., Schutgens, R. E., Lafeber, F. P., Roepstorff, K. & Mastbergen, S. C., Apr 2017, In: Osteoarthritis and Cartilage. 25, S1, p. S156-S157

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  9. Published

    Markers of Oxidative Stress in Dogs with Myxomatous Mitral Valve Disease are Influenced by Sex, Neuter Status, and Serum Cholesterol Concentration

    Reimann, Maria Josefine, Haggstrom, J., Moller, J. E., Lykkesfeldt, Jens, Falk, T. & Olsen, Lisbeth Høier, 2017, In: Journal of Veterinary Internal Medicine. 31, 2, p. 295-302 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Mitral Regurgitation Severity and Left Ventricular Systolic Dimension Predict Survival in Young Cavalier King Charles Spaniels

    Reimann, Maria Josefine, Moller, J. E., Haggstrom, J., Martinussen, Torben, Zatrazemi, S. S. C., Svanholm, L., Nielsen, L. B. M., Pedersen, H. D. & Olsen, Lisbeth Høier, 2017, In: Journal of Veterinary Internal Medicine. 31, 4, p. 1008-1016 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ETB receptors via the protein kinase MEK-ERK1/2 signaling pathway in rat

    Skovsted, Gry Freja, Kruse, L. S., Berchtold, L. A., Grell, A., Warfvinge, K. & Edvinsson, L., 1 Mar 2017, In: PLOS ONE. 12, 3, 18 p., e0174119.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Vitamin C deficiency reduces muscarinic receptor coronary artery vasoconstriction and plasma tetrahydrobiopterin concentration in guinea pigs

    Skovsted, Gry Freja, Tveden-Nyborg, Pernille, Lindblad, M. M., Hansen, S. N. & Lykkesfeldt, Jens, 2017, In: Nutrients. 9, 7, 14 p., 691.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Quality of life assessment in dogs and cats receiving chemotherapy: a review of current methods

    Vøls, Kåre Kryger, Heden, M. A., Kristensen, Annemarie T. & Sandøe, Peter, 2017, In: Veterinary and Comparative Oncology. 15, 3, p. 684–691 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  14. 2016
  15. Published

    Anti-RANKL treatment inhibits erosive joint destruction and lowers inflammation but has no effect on bone formation in the delayed-type hypersensitivity arthritis (DTHA) model

    Atkinson, S. M., Bleil, J., Maier, R., Kuehl, A. A., Thorn, M., Serikawa, K., Fox, B., Kruse, K., Haase, C., Skov, Søren, Nansen, A. & Syrbe, U., 23 Jan 2016, In: Arthritis Research & Therapy. 18, 12 p., 28.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Depletion of regulatory T cells leads to an exacerbation of delayedtype hypersensitivity arthritis in C57BL/6 mice that can be counteracted by IL-17 blockade

    Atkinson, S. M., Hoffmann, U., Bach, E., Danneskiold-Samsøe, Niels Banhos, Kristiansen, Karsten, Serikawa, K., Fox, B., Kruse, K., Haase, C., Skov, Søren & Nansen, A., 2016, In: Disease Models & Mechanisms. 9, p. 427-440 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Breeding Restrictions Decrease the Prevalence of Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels over an 8-to 10-Year Period

    Birkegård, A. C., Reimann, Maria Josefine, Martinussen, Torben, Haggstrom, J., Pedersen, H. D. & Olsen, Lisbeth Høier, 2016, In: Journal of Veterinary Internal Medicine. 30, 1, p. 63-68 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Zebrafisken - en holistisk miljømodel

    Buchmann, Kurt, Kania, Per, Haarder, S. & Jørgensen, Louise von Gersdorff, 25 Jan 2016, Villum Fonden - Velux Fonden: årsskrift 2015. Søborg: Villum Fonden, p. 52-58 7 p. (Villum Fonden - Velux Fonden : årsskrift, Vol. 2015).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  19. Published

    The F8(-/-) rat as a model of hemophilic arthropathy

    Christensen, K. R., Roepstorff, K., Wiinberg, B., Hansen, Axel Kornerup, Tranholm, M., Nielsen, Lise Nikolic & Kjelgaard-Hansen, M., Jun 2016, In: Journal of Thrombosis and Haemostasis. 14, 6, p. 1216-1225 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice

    Christophersen, D. V., Raun Jacobsen, N., Guerra Andersen, M. H., Connell, S. P., Barfod, K. K., Thomsen, Morten Bækgaard, Miller, M. R., Duffin, R., Lykkesfeldt, Jens, Vogel, U. B., Wallin, E. H. R., Loft, Steffen, Roursgaard, Martin & Møller, Peter, 14 Sep 2016, In: Toxicology. 371, p. 29-40 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Similar Adiponectin Levels in Obese Normotensive and Obese Hypertensive Men and No Vasorelaxant Effect of Adiponectin on Human Arteries

    Dreier, R., Asferg, C., Berg, J. O., Andersen, U. B., Flyvbjerg, A., Frystyk, J., Linneberg, Allan René, Jeppesen, J. L., Edvinsson, L. & Skovsted, Gry Freja, Feb 2016, In: Basic & Clinical Pharmacology & Toxicology. 118, 2, p. 128–135 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes

    Flethøj, M., Schwarzwald, C. C., Haugaard, M. M., Carstensen, Helena, Kanters, Jørgen K., Olsen, Lisbeth Høier & Buhl, Rikke, Jul 2016, In: Journal of Veterinary Internal Medicine. 30, 4, p. 1260-1269 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    L-dehydroascorbic acid can substitute L-ascorbic acid as dietary vitamin C source in guinea pigs

    Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Redox Biology. 7, p. 8-13 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Comparison of two chemically-induced colitis-models in adult zebrafish, using optical projection tomography and novel transcriptional markers

    Haarder, S., Kania, Per, Holm, T., Otani, M. & Buchmann, Kurt, 20 Dec 2016, In: Open Journal of Immunology. 6, p. 154-180 27 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Gall midges (Diptera: Cecidomyiidae) new to the Danish fauna

    Haarder, S., Bruun, Hans Henrik, Harris, K. M. & Skuhravá, M., 2016, In: Entomologisk Tidskrift. 137, p. 79-98 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Maternal vitamin C deficiency does not reduce hippocampal volume and beta-tubulin III intensity in prenatal Guinea pigs

    Hansen, S. N., Schjoldager, J. G., Paidi, M. D., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, Jul 2016, In: Nutrition Research. 36, 7, p. 696-702

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Dyslipidemia: Obese or Not Obese-That Is Not the Question

    Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Dec 2016, In: Current Obesity Reports. 5, 4, p. 405-412

    Research output: Contribution to journalReviewResearchpeer-review

  28. Published

    Normal Weight Dyslipidemia: Is It All About the Liver?

    Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Mar 2016, In: Obesity. 24, 3, p. 556-567 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    High-fat but not sucrose intake is essential for induction of dyslipidemia and non-alcoholic steatohepatitis in guinea pigs

    Ipsen, David Højland, Tveden-Nyborg, Pernille, Rolin, B., Rakipovski, G., Beck, M., Mortensen, L. W., Færk, L., Heegaard, P. M. H., Møller, Peter & Lykkesfeldt, Jens, 2016, In: Nutrition & Metabolism. 13, p. 51

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Rodent model choice has major impact on variability of standard preclinical readouts associated with diabetes and obesity research

    Jensen, Victoria Svop, Porsgaard, T., Lykkesfeldt, Jens & Hvid, H., 15 Aug 2016, In: American Journal of Translational Research. 8, 8, p. 3574-3584

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Histopathological nerve and skeletal muscle changes in rats subjected to persistent insulin-induced hypoglycemia

    Jensen, Vivi Flou Hjorth, Mølck, A., Heydenreich, A., Jensen, K. J., Bertelsen, L. O., Alifrangis, L., Andersen, L., Søeborg, H., Chapman, M., Lykkesfeldt, Jens & Bøgh, I. B., Jan 2016, In: Toxicologic Pathology. 29, 1, p. 17-30 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Oxidative costs of reproduction in mouse strains selected for different levels of food intake and which differ in reproductive performance

    Jothery, A. H. A., Vaanholt, L. M., Mody, N., Arnous, A., Lykkesfeldt, Jens, Bunger, L., Hill, W. G., Mitchell, S. E., Allison, D. B. & Speakman, J. R., 14 Nov 2016, In: Scientific Reports. 6, 12 p., 36353 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Is Diabetes Associated with Lower Vitamin C Status in Pregnant Women? A Prospective Study

    Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, Oct 2016, In: International Journal for Vitamin and Nutrition Research. 86, 5-6, p. 184-189

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Strategies for Using Plagiarism Software in the Screening of Incoming Journal Manuscripts: Recommendations Based on a Recent Literature Survey

    Lykkesfeldt, Jens, Aug 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 2, p. 161-164

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Antibody response to recombinant human coagulation factor VIII in a new rat model of severe hemophilia A

    Löfgren, Karin Maria, Sondergaard, H., Skov, Søren, Weldingh, K. N., Tranholm, M. & Wiinberg, B., Apr 2016, In: Journal of Thrombosis and Haemostasis. 14, 4, p. 747-756

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Joint bleeds increase the inhibitor response to human factor VIII in a rat model of severe haemophilia A

    Löfgren, Karin Maria, Søndergaard, H., Skov, Søren & Wiinberg, B., Sep 2016, In: Haemophilia. 22, 5, p. 772-779 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Non-genetic risk factors in haemophilia A inhibitor management: the danger theory and the use of animal models

    Löfgren, Karin Maria, Søndergaard, H., Skov, Søren & Wiinberg, B., Sep 2016, In: Haemophilia. 22, 5, p. 657-666 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  38. Published

    Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings

    Madsen, M. F., Kanters, Jørgen K., Pedersen, P. J., Haugaard, M. M., Carstensen, Helena, Olsen, Lisbeth Høier & Buhl, Rikke, 28 Nov 2016, In: BMC Veterinary Research. 12, 10 p., 266.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Changes in heart rate, arrhythmia frequency, and cardiac biomarker values in horses during recovery after a long-distance endurance ride

    Madsen, M. F., Kanters, Jørgen K., Haugaard, M. M., Pedersen, P. J., Carstensen, Helena, Balling, J. D., Olsen, Lisbeth Høier & Buhl, Rikke, 1 May 2016, In: Journal of the American Veterinary Medical Association. 248, 9, p. 1034-1042 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published
  41. Published

    Does Glucagon-like Peptide-1 Ameliorate Oxidative Stress in Diabetes? Evidence Based on Experimental and Clinical Studies

    Petersen, Karen Ekkelund, Rakipovski, G., Raun, K. & Lykkesfeldt, Jens, 2016, In: Current Diabetes Reviews. 12, 4, p. 331-358 28 p.

    Research output: Contribution to journalReviewResearchpeer-review

  42. Published

    Pulsatile Hyperglycaemia Induces Vascular Oxidative Stress and GLUT 1 Expression More Potently than Sustained Hyperglycaemia in Rats on High Fat Diet

    Rakipovski, G., Lykkesfeldt, Jens & Raun, K., 20 Jan 2016, In: P L o S One. 11, 1, e0147412.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Simvastatin and oxidative stress in humans: A randomized, double-blinded, placebo-controlled clinical trial

    Rasmussen, S. T., Andersen, Jon Thor Trærup, Nielsen, T. K., Cejvanovic, V., Petersen, K. M., Henriksen, T., Weimann, A., Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2016, In: Redox Biology. 9, p. 32-38

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Increased serum C-reactive protein concentrations in dogs with congestive heart failure due to myxomatous mitral valve disease

    Reimann, Maria Josefine, Ljungvall, I., Hillstrom, A., Møller, J. E., Hagman, R., Falk, T., Hoglund, K., Haggstrom, J. & Olsen, Lisbeth Høier, Mar 2016, In: Veterinary Journal. 209, p. 113-118

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Penetration of antimicrobials to pulmonary epithelial lining fluid and muscle and impact of drug physicochemical properties determined by microdialysis

    Rottbøll, Lisa Amanda Holm & Friis, C., 2016, In: Journal of Pharmacological and Toxicological Methods. 78, p. 58-65 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines

    Roursgaard, Martin, Knudsen, K. B., Northeved, H., Persson, M., Christensen, T., Kumar, P. E. K., Permin, A., Andresen, T. L., Gjetting, T., Lykkesfeldt, Jens, Vesterdal, L. K., Loft, Steffen & Møller, Peter, Oct 2016, In: Toxicology in Vitro. 36, p. 164-171 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Modulating the gut microbiota improves glucose tolerance, lipoprotein profile and atherosclerotic plaque development in ApoE-deficient mice

    Rune, Ida, Rolin, B., Larsen, C. S., Nielsen, Dennis Sandris, Kanter, J. E., Bornfeldt, K. E., Lykkesfeldt, Jens, Buschard, K., Kirk, R. K., Christoffersen, B., Fels, J. J., Josefsen, K., Kihl, Pernille & Hansen, Axel Kornerup, 2016, In: P L o S One. 11, 1, 16 p., e0146439.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Simultaneous quantification of monoamine neurotransmitters and their biogenic metabolites intracellularly and extracellularly in primary neuronal cell cultures and in sub-regions of guinea pig brain

    Schou-Pedersen, A. M. V., Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 15 Aug 2016, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1028, p. 222-230 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Reduced Mechanical Stretch Induces Enhanced Endothelin B Receptor-mediated Contractility via Activation of Focal Adhesion Kinase and Extra Cellular-regulated Kinase 1/2 in Cerebral Arteries from Rat

    Spray, S., Rasmussen, M. N. P., Skovsted, Gry Freja, Warfvinge, K., Sheykhzade, Majid & Edvinsson, L., Jun 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 1, p. 68-77 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Spontaneous bleeds in the elbows of F8-/- rats cause development of blood-induced joint disease closely resembling human hemophilic arthropathy

    Thyme, A. P., Vøls, Kåre Kryger, Christensen, K. R., Löfgren, Karin Maria, Wiinberg, B., Kvist, P. H., Kjelgaard-Hansen, M., Roepstorff, K., Nielsen, Lise Nikolic & Tranholm, M., 2016.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  51. Published

    Diet-induced dyslipidemia leads to nonalcoholic fatty liver disease and oxidative stress in guinea pigs

    Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland, Thiessen, T. S., Feldmann, L. D. B., Lindblad, M. M., Jensen, Henrik Elvang & Lykkesfeldt, Jens, 1 Feb 2016, In: Translational Research. 168, p. 146-160 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Vitaminer til hjernen

    Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Aktuel Naturvidenskab. 2016, 4, p. 8-11 4 p.

    Research output: Contribution to journalJournal articleResearch

  53. Published

    Establishment and use of surgical rat models for assessment of organ specific in vivo clearance

    Vestergaard, Bill, Jun 2016, In: Danish Medical Journal. 63, 6, 17 p., B5247.

    Research output: Contribution to journalReviewResearchpeer-review

  54. Published

    The kidneys play a central role in the clearance of rhGH in rats

    Vestergaard, Bill, Thygesen, P., Kreilgaard, M., Fels, J. J., Lykkesfeldt, Jens & Agerso, H., 30 Apr 2016, In: European Journal of Pharmaceutical Sciences. 86, p. 29-33

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 2015
  56. Published

    Distribution of vitamin C is tissue specific with early saturation of the brain and adrenal glands following differential oral dose regimens in guinea pigs

    Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2015, In: British Journal of Nutrition. 113, 10, p. 1539-1549 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Thick methacrylate sections devoid of lost caps simplify stereological quantifications based on the optical fractionator design

    Andersen, S. H., Lykkesfeldt, Jens & Larsen, J. O., 15 Sep 2015, In: Anatomical Record. 298, 12, p. 2141-2150 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Treatment with anti-C5aR mAb leads to early-onset clinical and mechanistic effects in the murine delayed-type hypersensitivity arthritis model

    Atkinson, S. M., Nansen, A., Usher, P. A., Sondergaard, B., Mackay, C. R., Friedrichsen, B., Chang, C., Tang, R., Skov, Søren, Haase, C. & Hornum, L., Nov 2015, In: Autoimmunity. 48, 7, p. 460-470 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    The influence of the young microbiome on inflammatory diseases - lessons from animal studies

    Bendtsen, K. M. B., Fisker, L., Hansen, Axel Kornerup, Hansen, Camilla Hartmann Friis & Nielsen, Dennis Sandris, 2015, In: Birth Defects Research. Part C: Embryo Today Reviews (Print). 105, 4, p. 278-295 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  60. Published

    Vascular gene expression in diet-induced atherosclerotic Gottingen minipigs

    Christensen, Liv von Voss, Skovgaard, K., Ludvigsen, T. P., Kirk, R. K., Christoffersen, B. O., Pedersen, H. D., Heegaard, P. M. & Olsen, Lisbeth Høier, Jul 2015, In: Atherosclerosis. 241, 1, p. E85-E85 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  61. Published

    Alpha-smooth muscle actin and serotonin receptors 2A and 2B in dogs with myxomatous mitral valve disease

    Cremer, Signe Emilie, Moesgaard, S. G., Rasmussen, C. E., Zois, N. E., Falk, T., Reimann, Maria Josefine, Cirera, Susanna, Aupperle, H., Oyama, M. A. & Olsen, Lisbeth Høier, 19 Mar 2015, In: Research in Veterinary Science. 100, p. 197-206 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Plasma and serum serotonin concentrations and surface-bound platelet serotonin expression in Cavalier King Charles Spaniels with myxomatous mitral valve disease

    Cremer, Signe Emilie, Kristensen, Annemarie T., Reimann, Maria Josefine, Eriksen, N. B., Petersen, S. F., Marschner, C. B., Tarnow, I., Oyama, M. A. & Olsen, Lisbeth Høier, 2015, In: American Journal of Veterinary Research. 76, 6, p. 520-531 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Serotonin markers show altered transcription levels in an experimental pig model of mitral regurgitation

    Cremer, Signe Emilie, Zois, N. E., Moesgaard, S. G., Ravn, N., Cirera, Susanna, Honge, J. L., Smerup, M. H., Hasenkam, J. M., Sloth, E., Leifsson, Páll S., Falk, B. T., Oyama, M. A., Orton, C., Martinussen, Torben & Olsen, Lisbeth Høier, 2015, In: The Veterinary Journal. 203, 2, p. 192-198 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Randall Selitto pressure algometry for assessment of bone-related pain in rats

    Falk, S., Ipsen, David Højland, Appel, C. K., Ugarak, A., Durup, D., Dickenson, A. H. & Heegaard, Anne-Marie, 2015, In: European Journal of Pain. 19, 3, p. 305-312 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Første fund af Aphanogmus hibernicus (Hymenoptera: Ceraphronidae) udenfor Irland.

    Haarder, S., 2015, In: Entomologiske Meddelelser. 83, 1, p. 31-32 2 p.

    Research output: Contribution to journalJournal articleResearch

  66. Published

    Lower limb ischaemia and reperfusion injury in healthy volunteers measured by oxidative and inflammatory biomarkers

    Halladin, N. L., Busch, S. V. E., Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 10 Apr 2015, In: Perfusion. 30, 1, p. 64-70 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Controlled exposure to particulate matter from urban street air is associated with decreased vasodilation and heart rate variability in overweight and older adults

    Hemmingsen, J. G., Rissler, J., Lykkesfeldt, Jens, Sallsten, G., Kristiansen, J., Møller, Peter & Loft, Steffen, 2015, In: Particle and Fibre Toxicology. 12, 10 p., 6.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    High-resolution gene expression profiling using RNA sequencing in patients with inflammatory bowel disease and in mouse models of colitis

    Holgersen, Kristine, Kutlu, B., Fox, B., Serikawa, K., Lord, J., Hansen, Axel Kornerup & Holm, T. L., Mar 2015, In: Journal of Crohn's and Colitis (JCC). 9, 6, p. 492-506 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Piroxicam treatment augments bone abnormalities in interleukin-10 knockout mice

    Holgersen, Kristine, Dobie, R., Farquharson, C., Van't Hof, R., Ahmed, S. F., Hansen, Axel Kornerup & Lindebo Holm, T., Feb 2015, In: Inflammatory Bowel Diseases. 21, 2, p. 257-266 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Asymmetric dimethylarginine in somatically healthy schizophrenia patients treated with atypical antipsychotics: a case-control study

    Jørgensen, Anders, Knorr, Ulla Benedichte Søsted, Soendergaard, M. G., Lykkesfeldt, Jens, Fink-Jensen, Anders, Poulsen, Henrik Enghusen, Jørgensen, Martin Balslev, Olsen, N. V. & Staalsø, J. M., 2015, In: B M C Psychiatry. 15, 8 p., 67.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Dietary magnesium deficiency affects gut microbiota and anxiety-like behaviour in C57BL/6N mice

    Jørgensen, B. M. P., Winther, G., Kihl, Pernille, Nielsen, Dennis Sandris, Wegener, G., Hansen, Axel Kornerup & Sørensen, Dorte Bratbo, 2015, In: Acta Neuropsychiatrica (Print). 27, 5, p. 307-311 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    The Zebra Fish IBD Model Assessed By Novel Probe Based TagMan Assays

    Kania, Per, Buchmann, Kurt & Haarder, S., 29 Jun 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  73. Published

    In vivo toxicity of cationic micelles and liposomes

    Knudsen, K. B., Northeved, H., Kumar Ek, P., Permin, A., Gjetting, T., Andresen, T. L., Larsen, S., Wegener, K. M., Lykkesfeldt, Jens, Jantzen, K., Loft, Steffen, Møller, Peter & Roursgaard, Martin, 25 Feb 2015, In: Nanomedicine: Nanotechnology, Biology and Medicine. 11, 2, p. 467-477 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Calcium signaling in coronary artery after reperfusion damage in rat model of acute myocardial infarct

    Kristiansen, S. B., Skovsted, Gry Freja, Sheykhzade, Majid & Edvinsson, L., Sep 2015, In: Acta Physiologica (Print). 215, Supplement, p. 3-4 7.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  75. Published

    Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals

    Ludvigsen, Trine Pagh, Kirk, R. K., Christoffersen, B. Ø., Pedersen, H. D., Martinussen, Torben, Kildegaard, J., Heegaard, P. M. H., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2015, In: Journal of Translational Medicine. 13, 12 p., 312.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Elimination of ascorbic acid after high-dose infusion in prostate cancer patients: a pharmacokinetic evaluation

    Nielsen, Torben Kjær, Højgaard, M., Andersen, J. T. T., Poulsen, Henrik Enghusen, Lykkesfeldt, Jens & Mikines, K. J., 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 4, p. 343-348 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Antimicrobial drug penetration into the pulmonary epithelial lining fluid and muscle measured by microdialysis in anesthetized pigs

    Rottbøll, Lisa Amanda Holm & Friis, C., Jul 2015, In: Journal of Veterinary Pharmacology and Therapeutics. 38, S1, p. 89 1 p., 1.12.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  78. Published

    Intrabronchial microdialysis: effects of probe localization on tissue trauma and drug penetration into the pulmonary epithelial lining fluid

    Rottbøll, Lisa Amanda Holm, Skovgaard, K., Barington, Kristiane, Jensen, Henrik Elvang & Friis, C., 2015, In: Basic & Clinical Pharmacology & Toxicology. 117, 4, p. 242-250 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Maternal vitamin C deficiency during pregnancy results in transient fetal and placental growth retardation in guinea pigs: [Plus] erratum

    Schjoldager, J. G., Paidi, M. D., Lindblad, M. M., Birck, M. M., Kjærgaard, A. B., Dantzer, V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2015, In: European Journal of Nutrition. 54, 4, p. 667-676 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    IL-33 promotes GATA-3 polarization of gut-derived T cells in experimental and ulcerative colitis

    Seidelin, Jakob Benedict, Coskun, M., Kvist, P. H., Holm, T. L., Holgersen, Kristine & Nielsen, Ole Haagen, Feb 2015, In: Journal of Gastroenterology. 50, 2, p. 180-190 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study

    Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Endothelin-1 and endothelin-3 regulate endothelin receptor expression in rat coronary arteries

    Skovsted, Gry Freja, Kilic, S. & Edvinsson, L., 2015, In: Basic & Clinical Pharmacology & Toxicology Online. 117, 5, p. 297-305 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Third-stage nematode larvae of Contracaecum osculatum from Baltic cod (Gadus morhua) elicit eosinophilic granulomatous reactions when penetrating the stomach mucosa of pigs

    Strøm, S. B., Haarder, S., Korbut, R., Mejer, H., Thamsborg, Stig Milan, Kania, Per & Buchmann, Kurt, 2015, In: Parasitology Research. 114, 3, p. 1217-1220 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Chronic dyslipidemia induces fatty liver disease in Guinea pigs

    Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland & Lykkesfeldt, Jens, Jul 2015, In: Atherosclerosis. 241, 1, p. e119-e120 2 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  85. Published

    Colonic lesions, cytokine profiles, and gut microbiota in plasminogen-deficient mice

    Vestergaard, Bill, Krych, Lukasz, Lund, L. R., Jørgensen, B. M. P., Hansen, Lars Hestbjerg, Jensen, Henrik Elvang, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2015, In: Comparative Medicine. 65, 5, p. 382-397 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Dietary magnesium deficiency alters gut microbiota and leads to depressive-like behaviour

    Winther, G., Jørgensen, B. M. P., Elfving, B., Nielsen, Dennis Sandris, Kihl, Pernille, Lund, S., Sørensen, Dorte Bratbo & Wegener, G., 2015, In: Acta Neuropsychiatrica (Print). 27, 3, p. 168-176 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. 2014
  88. Published

    Effect of melatonin on human nighttime endotoxaemia: randomized, double-blinded, cross-over study

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, 6, p. 1057-1063 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Melatonin suppresses markers of inflammation and oxidative damage in a human daytime endotoxemia model

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: Journal of Critical Care. 29, 1, p. 184.e9-184.e13 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Pronounced inflammatory response to endotoxaemia during nighttime: a randomised cross-over trial

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, I., 2014, In: PloS one. 9, 1, 7 p., e87413.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Neonatal Vitamin C Deficiency and Impaired Brain Development: A Dose-response Study

    Andersen, S. H., 2014, Copenhagen University.

    Research output: Book/ReportPh.D. thesisResearch

  92. Published

    Non-terminal blood sampling techniques in Guinea pigs

    Birck, M. M., Tveden-Nyborg, Pernille, Lindblad, M. M. & Lykkesfeldt, Jens, 2014, In: Journal of Visualized Experiments. 92, e51982.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs

    Boonen, H. C. M., Moesgaard, S. G., Birck, M. M., Christoffersen, B. Ø., Cirera, Susanna, Heegaard, P. M. H., Højbøge, T. R., Jensen, Lars Jørn, Mortensen, A., Olsen, Lisbeth Høier, Sheykhzade, Majid, Tang, J. & Lykkesfeldt, Jens, 2014, In: Pflügers ARchiv (European Journal of Physiology). 466, 12, p. 2167-2176 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    New records of gall midges (Diptera: Cecidomyiidae) from Denmark

    Bruun, Hans Henrik, Haarder, S., Jørgensen, J. & Skuhravá, M., 2014, In: Entomologiske Meddelelser. 82, 1, p. 25-37 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Applicability of chronic inflammation models for mechanistic in vivo studies

    Christensen, A. D., 2014

    Research output: Book/ReportPh.D. thesisResearch

  96. Published

    The role of neutrophils and G-CSF in DNFB-induced contact hypersensitivity in mice

    Christensen, A. D., Skov, Søren & Haase, C., 2014, In: Immunity, Inflammation and Disease. 2, 1, p. 21-34 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    High-fat feeding increases hepatic vitamin C synthesis and its circulatory mobilization in mice

    Christensen, B. T., Hansen, Axel Kornerup & Lykkesfeldt, Jens, 2014, In: European Journal of Nutrition. 53, 6, p. 1441-1444 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Antioxidant supplementation for lung disease in cystic fibrosis

    Ciofu, Oana & Lykkesfeldt, Jens, 2014, In: The Cochrane library. 2014, 8, 87 p., CD007020.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    High-level serotonin-binding in subpopulation of highly-activated platelets in Cavalier King Charles Spaniels with myxomateous valve disease

    Cremer, S. E., Kristensen, Annemarie T., Reimann, M. J., Eriksen, N. B., Petersen, S. F., Marschner, C. B., Tarnow, I., Oyama, M. A. & Olsen, Lisbeth Høier, 2014. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  100. Published

    High-level serotonin binding in subpopulation of highly activated platelets in cavalier King charles spaniels with myxomatous mitral valve disease

    Cremer, Signe Emilie, Kristensen, Annemarie T., Reimann, Maria Josefine, Eriksen, N. B., Petersen, S. F., Marschner, C. B., Tarnow, I., Oyama, M. A. & Olsen, Lisbeth Høier, 2014.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  101. Published

    Serotonin concentration is elevated in platelet-rich plasma and left ventricular myocardial and mitral valve leaflet tissue in dogs with myxomatous mitral valve disease

    Cremer, Signe Emilie, Singletary, G. E., Olsen, Lisbeth Høier, Wallace, K., Häggström, J., Ljungvall, I., Höglund, K., Reynolds, C. A., Pizzinat, N. & Oyama, M. A., 2014.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  102. Published

    Serotonin concentrations in platelets, plasma, mitral valve leaflet, and left ventricular myocardial tissue in dogs with myxomatous mitral valve disease

    Cremer, Signe Emilie, Singletary, G. E., Olsen, Lisbeth Høier, Wallace, K., Häggström, J., Ljungvall, I., Höglund, K., Reynolds, C. A., Pizzinat, N. & Oyama, M. A., 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1534-1540 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Strong association between activated valvular interstitial cells and histopathological lesions in porcine model of induced mitral regurgitation

    Cremer, Signe Emilie, Zois, N. E., Moesgaard, S. G., Ravn, N., Cirera, Susanna, Honge, J. L., Smerup, M. H., Hasenkam, J. M., Sloth, E., Leifsson, Páll S., Falk, B. T., Oyama, M. A., Orton, C., Martinussen, Torben & Olsen, Lisbeth Høier, 2014, In: International Journal of Cardiology. 174, 2, p. 443-446 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  104. Published

    Transfer of gut microbiota from lean and obese mice to antibiotic-treated mice

    Ellekilde, M., Selfjord, E. M., Larsen, C. S., Jakesevic, M., Rune, Ida, Christensen, B. T., Vogensen, Finn Kvist, Nielsen, Dennis Sandris, Bahl, M. I., Licht, T. R., Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2014, In: Scientific Reports. 4, 8 p., 5922.

    Research output: Contribution to journalJournal articleResearchpeer-review