Lifepharm

  1. 2024
  2. Published

    Decreased Heart Rate After Dapagliflozin Treatment In Gottingen Minipigs With Chronic Myocardial Infarction

    Debes, Karina Poulsdóttir, Lyhne, Mille Kronborg, Hinz, K., Sand, K. P., Rose, V. H., Flethøj, M., Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2024, In: Journal of Cardiac Failure. 30, 1, p. 267-268

    Research output: Contribution to journalConference abstract in journalpeer-review

  3. Published
  4. 2023
  5. Published

    Effect of Remote Ischaemic Preconditioning on Perioperative Endothelial Dysfunction in Non-Cardiac Surgery: A Randomised Clinical Trial

    Wahlstrøm, K. L., Hansen, H. F., Kvist, M., Burcharth, Jakob, Lykkesfeldt, Jens, Gögenur, Ismail & Ekeloef, S., 16 Mar 2023, In: Cells. 12, 6, 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  6. Published

    In vivo effect of rFVIII and rFVIIa in hemophilia A rats evaluated by the Tail Vein Transection Bleeding Model

    Stagaard, Rikke, Øvlisen, Gabi Overgaard, Klæbel, J. H., Danielsen, D., Lund, A., Elm, T. & Ley, C. D., 2023, In: Journal of Thrombosis and Haemostasis. 21, 5, p. 1189-1199 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  7. Published
  8. Published

    Does Aging Affect Vitamin C Status Relative to Intake? Findings from NHANES 2017-2018

    Carr, A. C. & Lykkesfeldt, Jens, 2023, In: Nutrients. 15, 4, 10 p., 892.

    Research output: Contribution to journalJournal articlepeer-review

  9. Published

    Effects of two- and twelve-weeks sodium-glucose cotransporter 2 inhibition on DNA and RNA oxidation: two randomized, placebo-controlled trials

    Larsen, E. L., Andersen, A., Kjær, L. K., Eickhoff, M. K., Frimodt-Møller, M., Persson, F., Rossing, Peter, Lykkesfeldt, Jens, Knop, Filip Krag, Vilsbøll, Tina, Rungby, Jørgen & Poulsen, Henrik Enghusen, 2023, In: Free Radical Research. 57, 2, p. 140-151

    Research output: Contribution to journalJournal articlepeer-review

  10. Published

    Factors Affecting the Vitamin C Dose-Concentration Relationship: Implications for Global Vitamin C Dietary Recommendations

    Carr, A. C. & Lykkesfeldt, Jens, 2023, In: Nutrients. 15, 7, 19 p., 1657.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Functional and morphological renal changes in a Göttingen Minipig model of obesity-related and diabetic nephropathy

    Christoffersen, B. Ø., Kristensen, C. A., Lindgaard, R., Kirk, R. K., Viuff, B. M., Kvist, P. H., Pedersen, H. D., Ludvigsen, T. P., Skovgaard, T., Fels, J. J., Martinussen, Torben, Christiansen, L. B., Cirera, Susanna & Olsen, Lisbeth Høier, 2023, In: Scientific Reports. 13, 13 p., 6017.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    Generation of eight hiPSCs lines from two pathogenic variants in CACNA1A using the CRISPR-Cas9 gene editing technology

    Rivera-Sánchez, P., Søndergaard, L., Wathikthinnakon, Methi, B. D. Magnusson, H., Frederiksen, Henriette Reventlow S, Aabæk Hammer, F., Taleb, R., Christian Cassidy, C., Tranholm Bruun, M., Tümer, Asuman Zeynep, Holst, B., Brasch-Andersen, C., Møller, R., Freude, Kristine & Chandrasekaran, Abinaya, 2023, In: Stem Cell Research. 71, 103193.

    Research output: Contribution to journalJournal articlepeer-review

  13. Published
  14. Accepted/In press

    Influence of general anaesthesia on circulating biomarkers of glucose metabolism in pigs

    Christoffersen, B., Bundgaard, C. J., Hjøllund, K. R., Fels, J. J., Boll, K. K., Lyhne, Mille Kronborg & Olsen, Lisbeth Høier, 2023, (Accepted/In press) In: Laboratory Animals.

    Research output: Contribution to journalJournal articlepeer-review

  15. Published
  16. Published

    No impact of polymorphism in the phosphodiesterase 5A gene in Cavalier King Charles Spaniels on pimobendan-induced inhibition of platelet aggregation response

    Reimann, Maria Josefine, Faisst, D. N., Knold, M., Meurs, K. M., Stern, J. A., Cremer, Signe Emilie, Møller, J. E., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2023, In: Journal of Veterinary Internal Medicine. 37, 6, p. 1947-2660

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    O11 | In vitro and in vivo effects of dapagliflozin on adenosine diphosphate induced platelet aggregation response in Göttingen minipigs

    Hinz, K., Lyhne, Mille Kronborg, Debes, Karina Poulsdóttir, Reimann, Maria Josefine, Flethøj, M., Bruun, Camilla Vibeke Sichlau, Ludvigsen, Trine Pagh, Kirchhoff, J., Jespersen, Thomas, Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2023, In: Journal of Veterinary Pharmacology and Therapeutics. 46, S1, p. 33-33 1 p., O11.

    Research output: Contribution to journalConference abstract in journal

  18. Published

    Role of S1P-receptor and Rho-kinase in myogenic tone in mesenteric and cerebral arteries of young vs. middle-aged mice

    Skovsted, Gry Freja, Aupetit, A., Björling , K., Haanes, K. A., Syberg, S., Jørgensen, N. R., Freude, Kristine, Pearson, J. T. & Jensen, Lars Jørn, 2023, In: Acta Physiologica. 239, S728, e14042.

    Research output: Contribution to journalConference abstract in journal

  19. Published

    The dietary regulation of LEAP2 depends on meal composition in mice

    Gradel, Anna Katrina Jógvansdóttir, Holm, Stephanie Kjærulff, Byberg, Sarah, Merkestein, M., Hogendorf, W. F. J., Lund, M. L., Buijink, Jesse A., Damgaard, J., Lykkesfeldt, Jens & Holst, Birgitte, 2023, In: FASEB Journal. 37, 6, 21 p., 22923.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    The intestinal permeability marker FITC-dextran 4kDa should be dosed according to lean body mass in obese mice

    Voetmann, Louise Marie, Rolin, B., Kirk, R. K., Pyke, C. & Hansen, Axel Kornerup, 2023, In: Nutrition and Diabetes. 13, 1.

    Research output: Contribution to journalJournal articlepeer-review

  21. E-pub ahead of print

    Validation of computed tomography as a diagnostic tool in guinea pigs with non-alcoholic fatty liver disease

    Lintrup, K., Ipsen, David Højland, Skat-Rørdam, Josephine, Lykkesfeldt, Jens, Tveden-Nyborg, Pernille & Buelund, Lene Elisabeth, 2023, (E-pub ahead of print) In: Laboratory Animals.

    Research output: Contribution to journalJournal articlepeer-review

  22. Published

    Vitamin C – a scoping review for Nordic Nutrition Recommendations 2023

    Lykkesfeldt, Jens & Carr, A. C., 2023, In: Food and Nutrition Research. 67, 19 p., 10300.

    Research output: Contribution to journalReviewpeer-review

  23. 2022
  24. Published

    A long‐term energy‐rich diet increases prefrontal bdnf in sprague‐dawley rats

    Virtuoso, Alessandro, Tveden-Nyborg, Pernille, Schou‐pedersen, A. M. V., Lykkesfeldt, Jens, Müller, H. K., Elfving, B. & Sørensen, Dorte Bratbo, 2022, In: Nutrients. 14, 1, 126.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    A porcine model of subcutaneous Staphylococcus aureus infection: a pilot study

    Nielsen, O. L., Mellergaard, M., Frees, Dorte, Larsen, M. N., Skov, Søren, Olsen, Lisbeth Høier & Reimann, Maria Josefine, 2022, In: APMIS - Journal of Pathology, Microbiology and Immunology. 130, 7, p. 359-370

    Research output: Contribution to journalJournal articlepeer-review

  26. Published

    CTLA4-Ig prevents development of neutralizing antibody formation after continuous treatment with human FVIII in HA rats

    Øvlisen, Gabi Overgaard, Thygesen, P., Weldingh, K. N., Bloem, E., Skov, Søren, Almholt, K., Lövgren, K. M., Ley, C. D. & Holm, T. L., 2022, In: Haemophilia. 28, 4, p. 568-577

    Research output: Contribution to journalJournal articlepeer-review

  27. Published

    Comparison of the neuromuscular effects of two infusion rates of rocuronium in anesthetized pigs

    Pedersen, Kamilla, Kruhøffer, L. L., Lykkesfeldt, Jens & Kousholt, B. S., 2022, In: Acta Veterinaria Scandinavica. 64, 38.

    Research output: Contribution to journalJournal articlepeer-review

  28. Published
  29. Published

    Effect of the sodium-glucose cotransporter-2 inhibitor dapagliflozinon platelet aggregation response in Cavalier King Charles Spanielswith and without cardiac disease

    Speitzer, A., Øgelund, E., Reimann, Maria Josefine, Møller, J. E., Skovsted, G. F., Lyhne, Mille Kronborg, Verma, S., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2022, In: Journal of Veterinary Internal Medicine. 36, 6, p. 2473 1 p.

    Research output: Contribution to journalConference abstract in journalpeer-review

  30. Published

    Efficacy of fibroblast growth factor 21 in non-alcoholic fatty liver disease in guinea pigs

    Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Basic & Clinical Pharmacology & Toxicology. 130, 3, p. 385-393

    Research output: Contribution to journalJournal articlepeer-review

  31. Published

    Electrocardiography and heart rate variability in Göttingen Minipigs: Impact of diurnal variation, lead placement, repeatability and streptozotocin-induced diabetes

    Lyhne, Mille Kronborg, Debes, Karina Poulsdóttir, Helgogaard, T., Vegge, A., Kildegaard, J., Pedersen-Bjergaard, Ulrik & Olsen, Lisbeth Høier, 2022, In: Journal of Pharmacological and Toxicological Methods. 118, 107221.

    Research output: Contribution to journalJournal articlepeer-review

  32. Published

    Estimation of Vitamin C Intake Requirements Based on Body Weight: Implications for Obesity

    Carr, A. C., Block, G. & Lykkesfeldt, Jens, 2022, In: Nutrients. 14, 7, 8 p., 1460.

    Research output: Contribution to journalJournal articlepeer-review

  33. Published

    Implantation of telemetric blood pressure transmitters in Göttingen Minipigs: Validation of 24-h systemic blood pressure and heart rate monitoring and influence of anaesthesia

    Carlsen, M. F., Christoffersen, B. Ø., Lindgaard, R., Pedersen, H. D. & Olsen, Lisbeth Høier, 2022, In: Journal of Pharmacological and Toxicological Methods. 115, 107168.

    Research output: Contribution to journalJournal articlepeer-review

  34. Published

    In vitro cell cultures of Brunner's glands from male mouse to study GLP-1 receptor function

    Voetmann, Louise Marie, Underwood, C. R., Rolin, B., Hansen, Axel Kornerup, Kirk, R. K., Pyke, C., Knudsen, L. B. & Frederiksen, K. S., 2022, In: American journal of physiology. Cell physiology. 322, 6, p. C1260-C1269

    Research output: Contribution to journalJournal articlepeer-review

  35. Published

    Lower Vitamin C Levels Are Associated With Less Improvement in Negative Symptoms in Initially Antipsychotic-Naïve Patients With First-Episode Psychosis

    Myken, A. N., Ebdrup, Bjørn, Sørensen, M. E., Broberg, B. V., Skjerbæk, M. W., Glenthøj, Birte Yding, Lykkesfeldt, Jens & Nielsen, Mette Ødegaard, 2022, In: The international journal of neuropsychopharmacology. 25, 8, p. 613-618 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  36. Published

    Marked gut microbiota dysbiosis and increased imidazole propionate are associated with a NASH Göttingen Minipig model

    Lützhøft, Ditte Olsen, Sinioja, T., Christoffersen, B., Jakobsen, Rasmus Riemer, Geng, Dawei, Ahmad, H. F. B., Straarup, E. M., Pedersen, K. M., Kot, Witold, Pedersen, H. D., Cirera, Susanna, Hyötyläinen, T., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2022, In: BMC Microbiology. 22, 1, 287.

    Research output: Contribution to journalJournal articlepeer-review

  37. Published

    Optimization of pig models for translation of subcutaneous pharmacokinetics of therapeutic proteins: Liraglutide, insulin aspart and insulin detemir

    Pedersen, K., Gradel, Anna Katrina Jógvansdóttir, Ludvigsen, T. P., Christoffersen, B. Ø., Fuglsang-Damgaard, C. A., Bendtsen, K. M., Madsen, S. H., Manfé, V. & Refsgaard, H. H. F., 2022, In: Translational Research. 239, p. 71-84

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Prolonged insulin-induced hypoglycaemia reduces ß-cell activity rather than number in pancreatic islets in non-diabetic rats

    Jensen, Vivi Flou Hjorth, Mølck, A. M., Nowak, J., Fels, J. J., Lykkesfeldt, Jens & Bøgh, I. B., 2022, In: Scientific Reports. 12, 14113.

    Research output: Contribution to journalJournal articlepeer-review

  39. Published

    Semaglutide treatment attenuates vessel remodelling in ApoE−/− mice following vascular injury and blood flow perturbation

    Jensen, Ditte Marie, Skovsted, Gry Freja, Bonde, M. F. B., Bentzon, J. F., Rolin, B., Franck, G., Ougaard, M. K. E., Voetmann, Louise Marie, Bachmann, J. C., Uryga, A., Pyke, C., Kirk, R. K., Hvid, H., Knudsen, L. B., Lykkesfeldt, Jens & Nyberg, M., 2022, In: Atherosclerosis Plus. 49, p. 32-41 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  40. Published

    The G213D variant in Nav1.5 alters sodium current and causes an arrhythmogenic phenotype resulting in a multifocal ectopic Purkinje-related premature contraction phenotype in human-induced pluripotent stem cell-derived cardiomyocytes

    Callø, Kirstine, Geryk, M., Freude, Kristine, Treat, J. A., Vold, V. A., Frederiksen, Henriette Reventlow S, Broendberg, A. K., Frederiksen, T. C., Jensen, H. K. & Cordeiro, J. M., 2022, In: Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 24, 12, p. 2015–2027

    Research output: Contribution to journalJournal articlepeer-review

  41. Published
  42. Published

    Vitamin C deficiency may delay diet-induced NASH regression in the guinea pig

    Skat-Rørdam, Josephine, Pedersen, Kamilla, Skovsted, Gry Freja, Gregersen, I., Vangsgaard, S., Ipsen, David Højland, Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2022, In: Antioxidants. 11, 1, 69.

    Research output: Contribution to journalJournal articlepeer-review

  43. 2021
  44. Published

    Activation of the renal GLP-1R leads to expression of Ren1 in the renal vascular tree

    Bjørnholm, K. D., Ougaard, M. E., Skovsted, Gry Freja, Knudsen, L. B. & Pyke, C., 2021, In: Endocrinology, Diabetes and Metabolism. 4, 3, e00234.

    Research output: Contribution to journalJournal articlepeer-review

  45. Published

    An Oligosaccharide Rich Diet Increases Akkermansia spp. Bacteria in the Equine Microbiota

    Lindenberg, F. C., Lützhøft, Ditte Olsen, Krych, Lukasz, Fielden, J., Kot, Witold, Frøkiær, Hanne, van Galen, G., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2021, In: Frontiers in Microbiology. 12, 666039.

    Research output: Contribution to journalJournal articlepeer-review

  46. Published

    Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected

    Christiansen, L. B., Dohlmann, T. L., Ludvigsen, T. P., Parfieniuk, E., Ciborowski, M., Szczerbinski, L., Kretowski, A., Desler, Claus, Tiano, L., Orlando, P., Martinussen, Torben, Olsen, Lisbeth Høier & Larsen, Steen, 2021, In: Scientific Reports. 11, 15 p., 2167.

    Research output: Contribution to journalJournal articlepeer-review

  47. Published

    BCPT policy for experimental and clinical studies

    Tveden-Nyborg, Pernille, Bergmann, T. K., Jessen, N., Simonsen, U. & Lykkesfeldt, Jens, 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 4-8

    Research output: Contribution to journalReviewpeer-review

  48. Published

    Co-bedding of Preterm Newborn Pigs Reduces Necrotizing Enterocolitis Incidence Independent of Vital Functions and Cortisol Levels

    Brunse, Anders, Peng, Y., Li, Y., Lykkesfeldt, Jens & Sangild, Per Torp, 2021, In: Frontiers in Pediatrics. 9, 636638.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Collagen remodelling and plasma ascorbic acid levels in patients suspected of inherited bleeding disorders harbouring germline variants in collagen‐related genes

    Fager Ferrari, M., Zetterberg, E., Rossing, Caroline Maria, Manon‐jensen, T., Pehrsson, M., Karsdal, M. A., Lykkesfeldt, Jens & Leinoe, E., 2021, In: Haemophilia. 27, 1, p. e69-e77

    Research output: Contribution to journalJournal articlepeer-review

  50. Published

    Decreased expression of the GLP-1 receptor after segmental artery injury in mice

    Bjørnholm, K. D., Povlsen, G. K., Ougaard, M. E., Pyke, C., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Skovsted, Gry Freja, 2021, In: The Journal of endocrinology. 248, 3, p. 289-301 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  51. Published

    Depleted myocardial coenzyme Q10 in cavalier king charles spaniels with congestive heart failure due to myxomatous mitral valve disease

    Christiansen, L. B., Reimann, Maria Josefine, Schou-Pedersen, A. M. V., Larsen, Steen, Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Antioxidants. 10, 2, p. 1-13 13 p., 161.

    Research output: Contribution to journalJournal articlepeer-review

  52. Published

    Diet-Dependent Changes of the DNA Methylome Using a Göttingen Minipig Model for Obesity

    Feng, Y., Cirera, Susanna, Taşöz, E., Liu, Y., Olsen, Lisbeth Høier, Christoffersen, B. Ø., Pedersen, H. D., Ludvigsen, T. P., Kirk, R. K., Schumacher-Petersen, Camilla, Deng, Y., Fredholm, Merete & Gao, Fei, 2021, In: Frontiers in Genetics. 12, 632859.

    Research output: Contribution to journalJournal articlepeer-review

  53. Published

    Differential effects of dietary components on glucose intolerance and non‐alcoholic steatohepatitis

    Skat-Rørdam, Josephine, Ipsen, David Højland, Hardam, P. D., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Nutrients. 13, 8, 2523.

    Research output: Contribution to journalJournal articlepeer-review

  54. Published

    Discrepancies in global vitamin C recommendations: a review of RDA criteria and underlying health perspectives

    Carr, A. C. & Lykkesfeldt, Jens, 2021, In: Critical Reviews in Food Science and Nutrition. 61, 5, p. 742-755 14 p.

    Research output: Contribution to journalReviewpeer-review

  55. Published

    Extracellular vesicles as drivers of non-alcoholic fatty liver disease: Small particles with big impact

    Ipsen, David Højland & Tveden-Nyborg, Pernille, 2021, In: Biomedicines. 9, 1, p. 1-13 13 p., 93.

    Research output: Contribution to journalReviewpeer-review

  56. Published

    Food intake rather than blood glucose levels affects the pharmacokinetic profile of insulin aspart in pigs

    Gradel, Anna Katrina Jógvansdóttir, Kildegaard, J., Porsgaard, T., Lykkesfeldt, Jens & Refsgaard, H. H. F., 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 6, p. 783-794

    Research output: Contribution to journalJournal articlepeer-review

  57. Published
  58. Published

    Hyperinsulinaemic hypoglycaemia in non-anaesthetized Göttingen minipigs induces a counter-regulatory endocrine response and electrocardiographic changes

    Lyhne, Mille Kronborg, Vegge, A., Povlsen, G. K., Slaaby, R., Kildegaard, J., Pedersen-Bjergaard, Ulrik & Olsen, Lisbeth Høier, 2021, In: Scientific Reports. 11, 11 p., 5983.

    Research output: Contribution to journalJournal articlepeer-review

  59. Published

    Insulin treatment improves liver histopathology and decreases expression of inflammatory and fibrogenic genes in a hyperglycemic, dyslipidemic hamster model of NAFLD

    Jensen, Victoria Svop, Fledelius, C., Zachodnik, C., Damgaard, J., Nygaard, H., Tornqvist, K. S., Kirk, R. K., Viuff, B. M., Wulff, E. M., Lykkesfeldt, Jens & Hvid, H., 2021, In: Journal of Translational Medicine. 19, 1, 80.

    Research output: Contribution to journalJournal articlepeer-review

  60. Published

    Liraglutide treatment improves endothelial function in the Ldlr-/- mouse model of atherosclerosis, and affects genes involved in vascular remodelling and inflammation

    Bjørnholm, K. D., Skovsted, Gry Freja, Mitgaard-Thomsen, A., Rakipovski, G., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Povlsen, G. K., 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 1, p. 103-114

    Research output: Contribution to journalJournal articlepeer-review

  61. Published
  62. Published
  63. Published

    Polymorphisms in the serotonin transporter gene and circulating concentrations of neurotransmitters in Cavalier King Charles Spaniels with myxomatous mitral valve disease

    Reimann, Maria Josefine, Fredholm, Merete, Cremer, Signe Emilie, Christiansen, L. B., Meurs, K. M., Møller, J. E., Häggström, J., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Journal of Veterinary Internal Medicine. 35, 6, p. 2596-2606

    Research output: Contribution to journalJournal articlepeer-review

  64. Published

    Tail vein transection bleeding model in fully anesthetized hemophilia A mice

    Carol Illa, Ariadna, Baumgarten, S., Danielsen, D., Larsen, K., Elm, T., Johansen, P. B., Knudsen, T., Lauritzen, B., Tranholm, M. & Ley, C. D., 2021, In: Journal of Visualized Experiments. 175, 17 p., e62952.

    Research output: Contribution to journalJournal articlepeer-review

  65. Published

    Temporal development of dyslipidemia and nonalcoholic fatty liver disease (Nafld) in syrian hamsters fed a high‐fat, high‐fructose, high‐cholesterol diet

    Jensen, Victoria Svop, Fledelius, C., Wulff, E. M., Lykkesfeldt, Jens & Hvid, H., 2021, In: Nutrients. 13, 2, p. 1-18 18 p., 604.

    Research output: Contribution to journalJournal articlepeer-review

  66. Published

    The development of nonalcoholic steatohepatitis is subjected to breeder dependent variation in guinea pigs

    Ipsen, David Højland, Agerskov, R. H., Klaebel, J. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Scientific Reports. 11, 2955.

    Research output: Contribution to journalJournal articlepeer-review

  67. Published

    The effect of acetylsalicylic acid and pentoxifylline in guinea pigs with non-alcoholic steatohepatitis

    Ipsen, David Højland, Skat-Rørdam, Josephine, Svenningsen, M., Andersen, Mia Trein, Latta, M., Buelund, Lene Elisabeth, Lintrup, K., Skaarup, R., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2021, In: Basic & Clinical Pharmacology & Toxicology. 128, 4, p. 583-593

    Research output: Contribution to journalJournal articlepeer-review

  68. Published

    The genetic consequences of dog breed formation - Accumulation of deleterious genetic variation and fixation of mutations associated with myxomatous mitral valve disease in cavalier King Charles spaniels: [+ correction]

    Axelsson, E., Ljungvall, I., Bhoumik, P., Conn, L. B., Muren, E., Ohlsson, Å., Olsen, L. H., Engdahl, K., Hagman, R., Hanson, J., Kryvokhyzha, D., Pettersson, M., Grenet, O., Moggs, J., Del Rio-Espinola, A., Epe, C., Taillon, B., Tawari, N., Mane, S., Hawkins, T. & 4 others, Hedhammar, Å., Gruet, P., Häggström, J. & Lindblad-Toh, K., 2021, In: PLOS Genetics. 17, 9, 34 p., e1009726.

    Research output: Contribution to journalJournal articlepeer-review

  69. Published

    The role of vitamin C in epigenetic cancer therapy

    Mikkelsen, Stine Ulrik, Gillberg, Linn, Lykkesfeldt, Jens & Grønbæk, Kirsten, 2021, In: Free Radical Biology and Medicine. 170, p. 179-193 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  70. Published

    Vitamin C: From Bench to Bedside

    Carr, A. C. & Lykkesfeldt, Jens, 2021, In: Nutrients. 13, 4, 3 p., 1102.

    Research output: Contribution to journalEditorialpeer-review

  71. Published
  72. 2020
  73. Published

    The counterregulatory response to hypoglycaemia in the pig

    Gradel, Anna Katrina Jógvansdóttir, Kildegaard, J., Ludvigsen, T. P., Porsgaard, T., Schou-Pedersen, A. M. V., Fels, J. J., Lykkesfeldt, Jens & Refsgaard, H. H. F., Oct 2020, In: Basic & Clinical Pharmacology & Toxicology. 127, 4, p. 278-286

    Research output: Contribution to journalJournal articlepeer-review

  74. Published

    Comparison of sublingual, facial and retro-bulbar blood sampling in mice in relation to animal welfare and blood quality

    Gjendal, K., Kiersgaard, M. K., Abelson, Klas, Sørensen, Dorte Bratbo & Ottesen, J. L., 1 May 2020, In: Journal of Pharmacological and Toxicological Methods. 103, 106680.

    Research output: Contribution to journalJournal articlepeer-review

  75. Published

    In vivo fluorescence molecular tomography of induced haemarthrosis in haemophilic mice: link between bleeding characteristics and development of bone pathology

    Vøls, Kåre Kryger, Kjelgaard-Hansen, M., Ley, C. D., Hansen, Axel Kornerup & Petersen, M., 14 Apr 2020, In: BMC Musculoskeletal Disorders. 21, 1, 10 p., 241.

    Research output: Contribution to journalJournal articlepeer-review

  76. Published

    A systematic Cochrane Review of antioxidant supplementation lung disease for cystic fibrosis

    Ciofu, Oana, Smith, S. & Lykkesfeldt, Jens, 2020, In: Paediatric Respiratory Reviews. 33, p. 28-29

    Research output: Contribution to journalComment/debatepeer-review

  77. Published

    Animal Models of Fibrosis in Nonalcoholic Steatohepatitis: Do They Reflect Human Disease?

    Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2020, In: Advances in Nutrition. 11, 6, p. 1696–1711

    Research output: Contribution to journalReviewpeer-review

  78. Published

    Ascorbate maintains a low plasma oxygen level

    Injarabian, L., Scherlinger, M., Devin, A., Ransac, S., Lykkesfeldt, Jens & Marteyn, B. S., 2020, In: Scientific Reports. 10, 1, 6 p., 10659.

    Research output: Contribution to journalJournal articlepeer-review

  79. Published

    Betamethasone Treatment for Atopic Dermatitis in Gut Microbiota Transplanted Mice

    Debes, Karina Poulsdóttir, Evdina, N. A., Laigaard, A., Larsen, J. M., Zachariassen, L. F., Hansen, Camilla Hartmann Friis & Hansen, Axel Kornerup, 2020, In: Comparative Medicine. 70, 1, p. 6-15 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  80. Published

    Cardiac adaptation in hibernating, free-ranging Scandinavian Brown Bears (Ursus arctos)

    Jørgensen, P. G., Evans, A., Kindberg, J., Olsen, Lisbeth Høier, Galatius, S. & Fröbert, O., 2020, In: Scientific Reports. 10, 1, 9 p., 247.

    Research output: Contribution to journalJournal articlepeer-review

  81. Published

    Central control of energy balance by amylin and calcitonin receptor agonists and their potential for treatment of metabolic diseases

    Zakariassen, Hannah Louise, John, L. M. & Lutz, T. A., 2020, In: Basic & Clinical Pharmacology & Toxicology. 127, 3, p. 163-177

    Research output: Contribution to journalReviewpeer-review

  82. Published

    Characterization of Atrial and Ventricular Structural Remodeling in a Porcine Model of Atrial Fibrillation Induced by Atrial Tachypacing

    Citerni, C., Kirchhoff, J., Olsen, Lisbeth Høier, Sattler, Stefan M, Gentilini, F., Forni, M., Zannoni, A., Grunnet, Morten, Edvardsson, N., Bentzen, Bo Hjorth & Diness, J. G., 2020, In: Frontiers in Veterinary Science. 7, 12 p., 179.

    Research output: Contribution to journalJournal articlepeer-review

  83. Published

    Dietary Intervention Accelerates NASH Resolution Depending on Inflammatory Status with Minor Additive Effects on Hepatic Injury by Vitamin E Supplementation

    Klaebel, J. H., Rakipovski, G., Andersen, B., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2020, In: Antioxidants. 9, 9, 9.

    Research output: Contribution to journalJournal articlepeer-review

  84. Published

    Effect of Repeated Exposure to Isoflurane on Nest Building and Burrowing in Mice

    Gjendal, K., Ottesen, J. L., Olsson, I. A. S. & Sørensen, Dorte Bratbo, 2020, In: Journal of the American Association for Laboratory Animal Science : JAALAS. 59, 1, p. 30-36 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  85. Published

    Effect of insulin on natriuretic peptide gene expression in porcine heart

    Terzic, D., Zois, N. E., Hunter, I., Christoffersen, Christina, Plomgaard, Peter Stendahl, Olsen, Lisbeth Høier, Jørgensen, Stine Ringholm, Pilegaard, Henriette & Goetze, Jens P. , 2020, In: Peptides. 131, 10 p., 170370.

    Research output: Contribution to journalJournal articlepeer-review

  86. Published

    Endothelial dysfunction and myocardial injury after major emergency abdominal surgery: a prospective cohort study

    Ekeloef, S., Oreskov, J. O., Falkenberg, A., Burcharth, J., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Gögenur, Ismail, 2020, In: BMC Anesthesiology. 20, 9 p., 67.

    Research output: Contribution to journalJournal articlepeer-review

  87. Published

    Fgf21 regulates hepatic metabolic pathways to improve steatosis and inflammation

    Keinicke, H., Sun, G., Mentzel, Caroline M. Junker, Fredholm, Merete, John, L. M., Andersen, B., Raun, K. & Kjaergaard, M., 2020, In: Endocrine Connections. 9, 8, p. 755-768 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  88. Published

    Formation and Glomerular Deposition of Immune Complexes in Mice Administered Human Antibodies: Evaluation of Dose, Frequency, and Biomarkers

    Boysen, L., Viuff, B. M., Landsy, L. H., Lykkesfeldt, Jens, Raymond, J. T., Price, S. A., Pelzer, H. & Lauritzen, B., 2020, In: Toxicologic Pathology. 48, 4, p. 570-585 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  89. Published

    Hypophosphatemic Hypovitaminosis D Induces Osteomalacia in the Adult Female Rat

    Durup, D., Diaz-delCastillo, M., Morgenlykke, J., Jensen, Lars Thorbjørn, Frandsen, E., Abelson, Klas, Pedersen, L., Lykkesfeldt, Jens, Ding, M., Jørgensen, Niklas Rye, Syberg, S., Petersen, S. & Heegaard, Anne-Marie, 2020, In: Endocrinology. 161, 8, bqaa100.

    Research output: Contribution to journalJournal articlepeer-review

  90. Published

    Importance of gestational hypoglycaemia for foetal malformations and skeletal development in rats

    Jensen, Vivi Flou Hjorth, Mølck, A. M., Lykkesfeldt, Jens, Fels, J. J., Andersen, L., Renaut, R., McGuigan, F., Åkesson, K. E. & Bøgh, I. B., 2020, In: Reproductive Toxicology. 91, p. 14-26 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  91. Published

    Inhibition of KCa2 and Kv11.1 Channels in Pigs With Left Ventricular Dysfunction

    Citerni, C., Kirchhoff, J., Olsen, Lisbeth Høier, Sattler, Stefan M, Grunnet, Morten, Edvardsson, N., Bentzen, Bo Hjorth & Diness, J. G., 2020, In: Frontiers in Pharmacology. 11, 11 p., 556.

    Research output: Contribution to journalJournal articlepeer-review

  92. Published

    Initial joint bleed volume in a delayed on-demand treatment setup correlates with subsequent synovial changes in hemophilic mice

    Vøls, Kåre Kryger, Kjelgaard-Hansen, M., Ley, C. D., Hansen, Axel Kornerup & Petersen, M., 2020, In: Animal models and experimental medicine. 3, 2, p. 160-168 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  93. Published

    Inner histopathologic changes and disproportionate zone volumes in foetal growth plates following gestational hypoglycaemia in rats

    Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B., Nowak, J., Viuff, B. M., Rasmussen, C. L. M., Voetmann, Louise Marie, Fels, J. J., Madsen, S. H., McGuigan, F. E., Tveden-Nyborg, Pernille, Lykkesfeldt, Jens & Akesson, K. E., 2020, In: Scientific Reports. 10, 1, 13 p., 5609.

    Research output: Contribution to journalJournal articlepeer-review

  94. Published

    Insulin Treatment Attenuates Small Nerve Fiber Damage in Rat Model of Type 2 Diabetes

    Andreasen, L. J., Kirk, R. K., Fledelius, C., Yorek, M. A., Lykkesfeldt, Jens & Akerstrom, T., 2020, In: Journal of Diabetes Research. 2020, 13 p., 9626398.

    Research output: Contribution to journalJournal articlepeer-review

  95. Published

    Intermittent mitral regurgitation in Cavalier King Charles spaniels: Short-term progression and influence of stress tests

    Reimann, Maria Josefine, Møller, J. E., Häggström, J., Åkerström, L. L. B., Martinussen, Torben & Olsen, Lisbeth Høier, 2020, In: Veterinary Journal. 258, 105457.

    Research output: Contribution to journalJournal articlepeer-review

  96. Published

    Malnutrition predisposes to endotoxin-induced edema and impaired inflammatory response in parenterally fed piglets

    Bæk, Ole, Fabiansen, C., Friis, Henrik, Ritz, C., Koch, Jørgen, Willesen, Jakob, Heegaard, P. M. H., Lykkesfeldt, Jens, Briend, A., Golden, M. H., Sangild, Per Torp & Thymann, Thomas, 2020, In: Journal of Parenteral and Enteral Nutrition. 44, 4, p. 668-676

    Research output: Contribution to journalJournal articlepeer-review

  97. Published

    Myocardial Changes in Diabetic and Nondiabetic Nonhuman Primates

    Krog, S., Ludvigsen, Trine Pagh, Nielsen, O. L., Kirk, R. K., Lykkegaard, K., Wulff, E. M., Møller, J. E., Pedersen, H. D. & Olsen, Lisbeth Høier, 2020, In: Veterinary Pathology. 57, 2, p. 332-343 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  98. Published

    On the effect of vitamin C intake on human health: How to (mis)interprete the clinical evidence

    Lykkesfeldt, Jens, 2020, In: Redox Biology. 34, 13 p., 101532.

    Research output: Contribution to journalReviewpeer-review

  99. Published

    Pharmacokinetics of Repeated Oral Dosing with Coenzyme Q10 in Cavalier King Charles Spaniels with Myxomatous Mitral Valve Disease

    Christiansen, L. B., Morsing, Malene Kjelin, Reimann, Maria Josefine, Martinussen, Torben, Birlie, Z., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2020, In: Antioxidants. 9, 9 p., 827.

    Research output: Contribution to journalJournal articlepeer-review

  100. Published

    Proteoglycan synthesis rate as a novel method to measure blood-induced cartilage degeneration in non-haemophilic and haemophilic rats

    Pulles, A. E., Vøls, Kåre Kryger, Christensen, K. R., Coeleveld, K., Hansen, Axel Kornerup, van Vulpen, L. F. D., Petersen, M., Mastbergen, S. C., Roepstorff, K., Schutgens, R. E. G., Kjelgaard-Hansen, M. & Lafeber, F. P. J. G., 2020, In: Haemophilia. 26, 3, p. e88-e96

    Research output: Contribution to journalJournal articlepeer-review

  101. Published

    Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice

    Zakariassen, Hannah Louise, John, L. M., Lykkesfeldt, Jens, Raun, K., Glendorf, T., Schaffer, L., Lundh, S., Secher, A., Lutz, T. A. & Le Foll, C., 2020, In: Neuropharmacology. 167, 107987.

    Research output: Contribution to journalJournal articlepeer-review

  102. Published

    Subcutaneous Administration of Insulin is Associated With Regional Differences in Injection Depot Variability and Kinetics in The Rat

    Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Lykkesfeldt, Jens, Brockhoff, P. M. B., Seested, T. & Refsgaard, H. H. F., 2020, In: Experimental and Clinical Endocrinology and Diabetes. 128, 5, p. 332-338 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  103. Published

    TL1A regulates adipose-resident innate lymphoid immune responses and enables diet-induced obesity in mice

    Tougaard, P., Martinsen, L. O., Lützhøft, Ditte Olsen, Jensen, Henrik Elvang, Flethøj, M., Vandenabeele, P., Pedersen, Anders Elm, Skov, Søren, Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2020, In: International journal of obesity (2005). 44, p. 1062–1074

    Research output: Contribution to journalJournal articlepeer-review

  104. Published

    The expression signatures in liver and adipose tissue from obese Göttingen Minipigs reveal a predisposition for healthy fat accumulation

    Cirera, Susanna, Taşöz, E., Juul Jacobsen, M., Schumacher-Petersen, Camilla, Østergaard Christoffersen, B., Kaae Kirk, R., Pagh Ludvigsen, T., Hvid, H., Duelund Pedersen, H., Olsen, Lisbeth Høier & Fredholm, Merete, 2020, In: Nutrition and Diabetes. 10, 1, 12 p., 9.

    Research output: Contribution to journalJournal articlepeer-review

  105. Published

    The potential of human milk oligosaccharides to impact the microbiota-gut-brain axis through modulation of the gut microbiota

    Al-Khafaji, A. H., Jepsen, Stine Dam, Christensen, K. R. & Vigsnæs, L. K., 2020, In: Journal of Functional Foods. 74, 104176.

    Research output: Contribution to journalReviewpeer-review

  106. Published

    Variation in diagnostic NAFLD/NASH read-outs in paired liver samples from rodent models

    Jensen, Victoria Svop, Tveden-Nyborg, Pernille, Zacho-Rasmussen, C., Quaade, Michelle Lauge, Ipsen, David Højland, Hvid, H., Fledelius, C., Wulff, E. M. & Lykkesfeldt, Jens, 2020, In: Journal of Pharmacological and Toxicological Methods. 101, 9 p., 106651.

    Research output: Contribution to journalJournal articlepeer-review

  107. 2019
  108. Published

    Oral vitamin C supplementation to patients with myeloid cancer on azacitidine treatment: Normalization of plasma vitamin C induces epigenetic changes

    Gillberg, Linn, mxz703, mxz703, Nasif, A., Ohtani, H., Madaj, Z., Hansen, Jakob Werner, Rapin, N., Mogensen, J. B., Liu, M., Dufva, I. H., Lykkesfeldt, Jens, Hajkova, P., Jones, P. A. & Grønbæk, Kirsten, 17 Oct 2019, In: Clinical Epigenetics. 11, 1, p. 143-153 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  109. Published

    Burrowing and nest building activity in mice after exposure to grid floor, isoflurane or ip injections

    Gjendal, K., Ottesen, J. L., Olsson, I. A. S. & Sørensen, Dorte Bratbo, 1 Jul 2019, In: Physiology and Behavior. 206, p. 59-66 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  110. Published

    A role of peroxisome proliferator-activated receptor gamma in non-alcoholic fatty liver disease

    Skat-Rørdam, Josephine, Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, May 2019, In: Basic & Clinical Pharmacology & Toxicology. 124, 5, p. 528-537

    Research output: Contribution to journalReviewpeer-review

  111. Published

    Peri-operative endothelial dysfunction in patients undergoing minor abdominal surgery: An observational study

    Busch, S. V. E., Godthaab, C., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Gögenur, I., Feb 2019, In: European Journal of Anaesthesiology. 36, 2, p. 130-134 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  112. Published

    18F-FDG PET/MR-imaging in a Göttingen Minipig model of atherosclerosis: Correlations with histology and quantitative gene expression

    Ludvigsen, T. P., Pedersen, S. F., Vegge, A., Ripa, Rasmus Sejersten, Johannesen, H. H., Hansen, Adam Espe, Löfgren, J., Schumacher-Petersen, Camilla, Kirk, R. K., Pedersen, H. D., Christoffersen, B. Ø., Ørbæk, M., Forman, Julie Lyng, Klausen, T. L., Olsen, Lisbeth Høier & Kjær, Andreas, 2019, In: Atherosclerosis. 285, p. 55-63 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  113. Published

    An ELISA for detection of complement-bound circulating immune complexes in mice

    Boysen, L., Lauritzen, B., Viuff, B. M., Lykkesfeldt, Jens & Landsy, L. H., 2019, In: Journal of Immunotoxicology. 16, 1, p. 82-86 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  114. Published

    Analytical validation of a conventional cardiac troponin I assay for dogs and cats

    Langhorn, Rebecca, Yrfelt, J. D., Stjernegaard, C. S., Christiansen, L. B., Olsen, Lisbeth Høier & Nielsen, Lise Nikolic, 2019, In: Veterinary Clinical Pathology. p. 36-41

    Research output: Contribution to journalJournal articlepeer-review

  115. Published

    Antioxidant supplementation for lung disease in cystic fibrosis

    Ciofu, Oana, Smith, S. & Lykkesfeldt, Jens, 2019, In: Cochrane Database of Systematic Reviews. 2019, 10, CD007020.

    Research output: Contribution to journalReviewpeer-review

  116. Published

    Atorvastatin and vitamin e accelerates NASH resolution by dietary intervention in a preclinical guinea pig model

    Klaebel, J. H., Skjødt, M., Skat-Rørdam, Josephine, Rakipovski, G., Ipsen, David Højland, Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 11, 20 p., 2834.

    Research output: Contribution to journalJournal articlepeer-review

  117. Published

    Bleed volume of experimental knee haemarthrosis correlates with the subsequent degree of haemophilic arthropathy

    Vøls, Kåre Kryger, Kjelgaard-Hansen, M., Ley, C. D., Hansen, Axel Kornerup & Petersen, M., 2019, In: Haemophilia. 25, 2, p. 324-333 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  118. Published

    Cross-species reactive monoclonal antibodies against the extracellular domains of the insulin receptor and IGF1 receptor

    Ørstrup, Laura Kofoed Hvidsten, Slaaby, R., Rasch, M. G., Rasmussen, N., Lund, S., Brandt, J., Schluckebier, G., Wang, Z., Lützen, A., Pedersen, T. Å., Hvid, H., Hansen, B. F. & Blume, N., 2019, In: Journal of Immunological Methods. 465, p. 20-26 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  119. Published

    Delayed insulin absorption correlates with alterations in subcutaneous depot kinetics in rats with diet‐induced obesity

    Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Brockhoff, P. M. B., Seested, T., Lykkesfeldt, Jens & Refsgaard, H. H. F., 2019, In: Obesity Science & Practice. 5, 3, p. 281-288

    Research output: Contribution to journalJournal articlepeer-review

  120. Published

    Determination of reduced and oxidized coenzyme Q10 in canine plasma and heart tissue by HPLC-ECD: Comparison with LC-MS/MS quantification

    Schou-Pedersen, A. M. V., Schemeth, D. & Lykkesfeldt, Jens, 2019, In: Antioxidants. 8, 8, 253.

    Research output: Contribution to journalJournal articlepeer-review

  121. Published

    Dietary LPS traces influences disease expression of the diet-induced obese mouse

    Lindenberg, F. C. B., Ellekilde, M., Thörn, A. C., Kihl, Pernille, Larsen, C. S., Hansen, Camilla Hartmann Friis, Metzdorff, S. B., Aalbæk, Bent & Hansen, Axel Kornerup, 2019, In: Research in Veterinary Science. 123, p. 195-203 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  122. Published

    Effects of exercise and dietary protein sources on adiposity and insulin sensitivity in obese mice

    Fjære, E., Myrmel, L. S., Lützhøft, Ditte Olsen, Andersen, H., Holm, J. B., Kiilerich, P., Hannisdal, R., Liaset, B., Kristiansen, Karsten & Madsen, L., 2019, In: Journal of Nutritional Biochemistry. 66, p. 98-109

    Research output: Contribution to journalJournal articlepeer-review

  123. Published

    Experimental non-alcoholic steatohepatitis in Göttingen Minipigs: Consequences of high fat-fructose-cholesterol diet and diabetes

    Schumacher-Petersen, Camilla, Christoffersen, B. O., Kirk, R. K., Ludvigsen, T. P., Zois, N. E., Pedersen, H. D., Vyberg, M. & Olsen, Lisbeth Høier, 2019, In: Journal of Translational Medicine. 17, 1, 110.

    Research output: Contribution to journalJournal articlepeer-review

  124. Published

    Expression of endothelin type B receptors in uterine artery smooth muscle cells from pregnant Guinea pigs

    Skovsted, Gry Freja, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2019, In: Placenta. 77, p. 8-15 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  125. Published

    Formation and glomerular deposition of immune complexes in mice administered bovine serum albumin: Evaluation of dose, frequency, and biomarkers

    Boysen, L., Viuff, B. M., Landsy, L. H., Price, S. A., Raymond, J. T., Lykkesfeldt, Jens & Lauritzen, B., 2019, In: Journal of Immunotoxicology. 16, 1, p. 191-200 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  126. Published

    Generic immune complex assay for detection of murine anti-drug-antibodies in complex with human IgG

    Boysen, L., Sprinkel, A. M. E., Lauritzen, B., Breinholt, J., Lykkesfeldt, Jens, Viuff, B. M. & Landsy, L. H., 2019, In: Biologicals. 60, p. 42-48 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  127. Published

    Glycemic control during pregnancy — A predictor of vitamin C status at labor in type 1 diabeticwomen?

    Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, 2019, In: Antioxidants. 8, 6, 153.

    Research output: Contribution to journalJournal articlepeer-review

  128. Published

    Hyperglycemia-induced transcriptional regulation of ROCK1 and TGM2 expression is involved in small artery remodeling in obese diabetic Göttingen Minipigs

    Ludvigsen, T. P., Olsen, Lisbeth Høier, Pedersen, H. D., Østergaard Christoffersen, B. & Jensen, Lars Jørn, 2019, In: Clinical Science. 133, 24, p. 2499–2516 18 p.

    Research output: Contribution to journalJournal articlepeer-review

  129. Published

    Molecular drivers of non-alcoholic steatohepatitis are sustained in mild-to-late fibrosis progression in a guinea pig model

    Ipsen, David Højland, Skat-Rørdam, Josephine, Tsamouri, M. M., Latta, M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Molecular Genetics and Genomics. 294, 3, p. 649–661

    Research output: Contribution to journalJournal articlepeer-review

  130. Published

    Myxømatøs mitralklapsygdom hos hund: Medicinsk behandling

    Reimann, Maria Josefine, Christiansen, L. B., Falk, B. T. & Olsen, Lisbeth Høier, 2019, In: Dansk Veterinaertidsskrift. 2019, 11, p. 38-43

    Research output: Contribution to journalJournal articlepeer-review

  131. Published

    Myxømatøs mitralklapsygdom hos hund: Metoder til diagnostik af behandlingskrævende sygdomsstadier

    Reimann, Maria Josefine, Christiansen, L. B., Falk, T. & Olsen, Lisbeth Høier, 2019, In: Dansk Veterinaertidsskrift. 2019, 9, p. 28-32

    Research output: Contribution to journalReviewpeer-review

  132. Published

    Når leveren bliver for fed

    Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Aktuel Naturvidenskab. 2019, 3, p. 28-31

    Research output: Contribution to journalJournal article

  133. Published

    Oral LPS Dosing Induces Local Immunological Changes in the Pancreatic Lymph Nodes in Mice

    Kihl, Pernille, Krych, Lukasz, Deng, Ling, Kildemoes, A. O., Laigaard, A., Hansen, L. H., Hansen, Camilla Hartmann Friis, Buschard, K., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2019, In: Journal of Diabetes Research. 2019, 9 p., 1649279.

    Research output: Contribution to journalJournal articlepeer-review

  134. Published

    Rapid inflammation and early degeneration of bone and cartilage revealed in a time-course study of induced haemarthrosis in haemophilic rats

    Christensen, K. R., Kjelgaard-Hansen, M., Nielsen, Lise Nikolic, Wiinberg, B., Althoehn, F. A., Poulsen, N. B., Vøls, Kåre Kryger, Thyme, A. P., Lovgren, K. M., Hansen, Axel Kornerup & Roepstorff, K., 2019, In: Rheumatology. 58, 4, p. 588-599

    Research output: Contribution to journalJournal articlepeer-review

  135. Published

    Reduced early life mucosal integrity decreases thymic cell counts and increases local, but not thymic regulatory, T cell recruitment: Gut mucosal integrity breach and thymic T cells

    Zakariassen, Hannah Louise, Bendtsen, K. M., Tougaard, P. & Hansen, Axel Kornerup, 2019, In: European Journal of Inflammation. 17, p. 1-16

    Research output: Contribution to journalJournal articlepeer-review

  136. Published
  137. Published
  138. Published

    The Pharmacokinetics of Vitamin C

    Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2019, In: Nutrients. 11, 10, 20 p., 2412.

    Research output: Contribution to journalReviewpeer-review

  139. Published

    The effect of melatonin on endothelial dysfunction in patients after acute coronary syndrome: The MEFACS randomized clinical trial

    Zahid, J. A., Isbrand, A., Kleif, J., Schou-Pedersen, A. V., Lykkesfeldt, Jens, Madsen, M. T. & Gögenur, Ismail, 2019, In: Journal of Pineal Research. 67, 3, e12600.

    Research output: Contribution to journalLetterpeer-review

  140. Published

    Towards a Göttingen minipig model of adult onset growth hormone deficiency: evaluation of stereotactic electrocoagulation method

    Ørstrup, Laura Kofoed Hvidsten, Tvilling, L., Orlowski, D., Zaer, H., Bjarkam, C. R., von Voss, P., Andersen, P. S., Christoffersen, B., Hedemann Sørensen, J. C., Laursen, T., Thygesen, P., Lykkesfeldt, Jens & Glud, A. N., 2019, In: Heliyon. 5, 11, 8 p., e02892.

    Research output: Contribution to journalJournal articlepeer-review

  141. Published

    Urine 5-hydroxyindoleacetic acid in Cavalier King Charles spaniels with preclinical myxomatous mitral valve disease

    Christiansen, L. B., Cremer, Signe Emilie, Helander, A., Madsen, T., Reimann, Maria Josefine, Møller, J. E., Höglund, K., Ljungvall, I., Häggström, J. & Olsen, Lisbeth Høier, 2019, In: Veterinary Journal. 250, p. 36-43 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  142. 2018
  143. Published

    Cardiac procholecystokinin expression during haemodynamic changes in the mammalian heart

    Goetze, Jens P. , Hunter, I., Zois, N. E., Terzic, D., Valeur, N., Olsen, Lisbeth Høier, Smith, J., Plomgaard, Peter Stendahl, Hansen, L. H., Rehfeld, Jens Frederik, Balling, L. & Gustafsson, Finn, Oct 2018, In: Peptides. 108, p. 7-13 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  144. Published

    Structural remodeling in cerebral and mesenteric arteries from obese Göttingen minipigs with or without diabetes

    Ludvigsen, Trine Pagh, Olsen, Lisbeth Høier, Pedersen, H. D., Østergaard Christoffersen, B. & Jensen, Lars Jørn, 13 Sep 2018, p. 467P-468P . 2 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  145. Published

    Analytical validation of a flow cytometric protocol for quantification of platelet microparticles in dogs

    Cremer, Signe Emilie, Krogh, Anne Kirstine Havnsøe, Hedström, M. E. K., Christiansen, L. B., Tarnow, I. & Kristensen, Annemarie T., Jun 2018, In: Veterinary Clinical Pathology. 47, 2, p. 186-196 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  146. Published

    Evaluating IL-21 as a Potential Therapeutic Target in Crohn's Disease

    Lindebo Holm, T., Tornehave, D., Søndergaard, H., Kvist, P. H., Sondergaard, B., Hansen, L., Hermit, M. B., Holgersen, K., Vergo , S., Frederiksen , K. S., Haase, C. & Lundsgaard, D., 10 Apr 2018, In: Gastroenterology Research and Practice. 2018, 22 p., 5962624.

    Research output: Contribution to journalJournal articlepeer-review

  147. Published

    Effect of maternal hypoglycaemia during gestation on materno-foetal nutrient transfer and embryo-foetal development: Evidence from experimental studies focused primarily on the rat

    Jensen, Vivi Flou Hjorth, Mølck, A. M., Lykkesfeldt, Jens & Bøgh, I. B., Apr 2018, In: Reproductive Toxicology. 77, p. 1-24 24 p.

    Research output: Contribution to journalReviewpeer-review

  148. Published

    Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by ternary complex factors and the actin cytoskeleton

    Krawczyk, K. K., Skovsted, Gry Freja, Perisic, L., Rippe, C., Dreier, R., Berg, J. O., Lykkesfeldt, Jens, Hedin, U. & Sward, K., Apr 2018.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  149. Published
  150. Published

    Vasomotor function in rat arteries after ex vivo and intragastric exposure to food-grade titanium dioxide and vegetable carbon particles

    Jensen, Ditte Marie, Christophersen, D. V., Sheykhzade, Majid, Skovsted, Gry Freja, Lykkesfeldt, Jens, Münter, R., Roursgaard, Martin, Loft, Steffen & Møller, Peter, 26 Feb 2018, In: Particle and Fibre Toxicology. 15, p. 1-18 12.

    Research output: Contribution to journalJournal articlepeer-review

  151. Published

    Comparison of Three Sample Preparation Procedures for the Quantification of L-Arginine, Asymmetric Dimethylarginine, and Symmetric Dimethylarginine in Human Plasma Using HPLC-FLD

    Schou-Pedersen, A. M. V. & Lykkesfeldt, Jens, 1 Feb 2018, In: Journal of Analytical Methods in Chemistry. 2018, 7 p., 6148515.

    Research output: Contribution to journalJournal articlepeer-review

  152. Published

    Proximal Neuropathy and Associated Skeletal Muscle Changes Resembling Denervation Atrophy in Hindlimbs of Chronic Hypoglycaemic Rats

    Jensen, Vivi Flou Hjorth, Molck, A. M., Soeborg, H., Nowak, J., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., Jan 2018, In: Basic & Clinical Pharmacology & Toxicology. 122, 1, p. 165-175

    Research output: Contribution to journalJournal articlepeer-review

  153. Published

    Symmetric Dimethylarginine in Cats with Hypertrophic Cardiomyopathy and Diabetes Mellitus

    Langhorn, Rebecca, Kieler, Ida Nordang, Koch, Jørgen, Christiansen, L. B. & Jessen, Lisbeth Rem, Jan 2018, In: Journal of Veterinary Internal Medicine. 32, 1, p. 57-63 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  154. Published

    A cafeteria diet alters the decision making strategy and metabolic markers in Sprague-Dawley male rats

    Virtuoso, Alessandro, Forkman, Björn, Sarruf, D. A., Tveden-Nyborg, Pernille & Sørensen, Dorte Bratbo, 2018, In: Applied Animal Behaviour Science. 199, p. 35-44 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  155. Published

    Abrogating fibrinolysis does not improve bleeding or rFVIIa/rFVIII treatment in a non-mucosal venous injury model in haemophilic rodents

    Stagaard, R., Flick, M. J., Bojko, B., Goryński, K., Goryńska, P. Z., Ley, C. D., Olsen, Lisbeth Høier & Knudsen, T., 2018, In: Journal of Thrombosis and Haemostasis. 16, 7, p. 1369-1382 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  156. Published

    Absence of functional compensation between coagulation factor VIII and plasminogen in double-knockout mice

    Stagaard, R., Ley, C. D., Almholt, K., Olsen, Lisbeth Høier, Knudsen, T. & Flick, M. J., 2018, In: Blood advances. 2, 22, p. 3126-3136 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  157. Published

    An Early Life Mucosal Insult Temporarily Decreases Acute Oxazolone-Induced Inflammation in Mice

    Bendtsen, K. M., Tougaard, P. & Hansen, Axel Kornerup, 2018, In: Inflammation. 41, 4, p. 1437-1447 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  158. Published

    Angiotensin-converting enzyme activity in Cavalier King Charles Spaniels with an ACE gene polymorphism and myxomatous mitral valve disease

    Meurs, K. M., Olsen, Lisbeth Høier, Reimann, Maria Josefine, Keene, B. W., Atkins, C. E., Adin, D., Aona, B., Condit, J., Defrancesco, T., Reina-Doreste, Y., Stern, J. A., Tou, S., Ward, J. & Woodruff, K., 2018, In: Pharmacogenetics and Genomics. 28, 2, p. 37-40 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  159. Published

    Basic & Clinical Pharmacology & Toxicology Policy for Experimental and Clinical studies

    Tveden-Nyborg, Pernille, Bergmann, T. K. & Lykkesfeldt, Jens, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 233-235 3 p.

    Research output: Contribution to journalComment/debatepeer-review

  160. Published

    Biochemical and cognitive effects of docosahexaenoic acid differ in a developmental and SorLA dependent manner

    Højland, A., Richner, M., Mølgaard, S., Dieu, R. S., Eskelund, A., Nykjær, A., Nyengaard, J. R., Lykkesfeldt, Jens, Glerup, S. & Nielsen, M. S., 2018, In: Behavioural Brain Research. 348, p. 90-100 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  161. Published

    Deregulation of obesity-relevant genes is associated with progression in BMI and the amount of adipose tissue in pigs

    Mentzel, Caroline M. Junker, Cardoso, T. F., Pipper, C. B., Jacobsen, M. J., Jørgensen, Claus Bøttcher, Cirera, Susanna & Fredholm, Merete, 2018, In: Molecular Genetics and Genomics. 293, 1, p. 129–136 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  162. Published

    Dietary fat stimulates development of NAFLD more potently than dietary fructose in Sprague-Dawley rats

    Jensen, Victoria Svop, Hvid, H., Damgaard, J., Nygaard, H., Ingvorsen, C., Wulff, E. M., Lykkesfeldt, Jens & Fledelius, C., 2018, In: Diabetology and Metabolic Syndrome. 10, 13 p., 4.

    Research output: Contribution to journalJournal articlepeer-review

  163. Published

    Dietary normalization from a fat, fructose and cholesterol-rich diet to chow limits the amount of myocardial collagen in a Göttingen Minipig model of obesity

    Andreasen, L. J., Krog, S., Ludvigsen, T. P., Nielsen, O. L., Møller, J. E., Christoffersen, B. Ø., Pedersen, H. D. & Olsen, Lisbeth Høier, 2018, In: Nutrition and Metabolism. 15, 64.

    Research output: Contribution to journalJournal articlepeer-review

  164. Published

    Does colour matter? Preference of mice for different colours of the house mouse igloo: An observational study

    Gjendal, K., Ottesen, J. L. & Sørensen, Dorte Bratbo, 2018, In: Scandinavian Journal of Laboratory Animal Science. 44, 6.

    Research output: Contribution to journalJournal articlepeer-review

  165. Published

    Early life vitamin C deficiency does not alter morphology of hippocampal CA1 pyramidal neurons or markers of synaptic plasticity in a Guinea pig model

    Hansen, S. N., Jørgensen, J. M. B., Nyengaard, J. R., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Nutrients. 10, 6, 749.

    Research output: Contribution to journalJournal articlepeer-review

  166. Published

    Expression of endothelin type B receptors (EDNRB) on smooth muscle cells is controlled by MKL2, ternary complex factors, and actin dynamics

    Krawczyk, K. K., Skovsted, Gry Freja, Perisic, L., Dreier, R., Berg, Jais Oliver, Hedin, U., Rippe, C. & Swärd, K., 2018, In: American Journal of Physiology - Cell Physiology. 315, 6, p. C873-C884

    Research output: Contribution to journalJournal articlepeer-review

  167. Published

    Eye, body or tail? Thermography as a measure of stress in mice

    Gjendal, K., Franco, N. H., Ottesen, J. L., Sørensen, Dorte Bratbo & Olsson, I. A. S., 2018, In: Physiology and Behavior. 196, p. 135-143 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  168. Published

    Factors Affecting the Absorption of Subcutaneously Administered Insulin: Effect on Variability

    Gradel, Anna Katrina Jógvansdóttir, Porsgaard, T., Lykkesfeldt, Jens, Seested, T., Gram-Nielsen, S., Kristensen, N. R. & Refsgaard, H., 2018, In: Journal of Diabetes Research. 2018, 17 p., 1205121.

    Research output: Contribution to journalReviewpeer-review

  169. Published

    Gut microbiota recovery and immune response in ampicillin-treated mice

    Castro Mejia, J. L., Jakesevic, M., Fabricius, N. F., Krych, Lukasz, Nielsen, Dennis Sandris, Kot, W., Bendtsen, K. M. B., Vogensen, Finn Kvist, Hansen, Camilla Hartmann Friis & Hansen, Axel Kornerup, 2018, In: Research in Veterinary Science. 118, p. 357-364 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  170. Published

    Have you tried spermine? A rapid and cost-effective method to eliminate dextran sodium sulfate inhibition of PCR and RT-PCR

    Krych, Lukasz, Kot, W., Bendtsen, K. M. B., Hansen, Axel Kornerup, Vogensen, Finn Kvist & Nielsen, Dennis Sandris, 2018, In: Journal of Microbiological Methods. 144, p. 1-7 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  171. Published

    Heterozygous mutations in GTP-cyclohydrolase-1 reduce BH4 biosynthesis but not pain sensitivity

    Nasser, A., Møller, A. T., Hellmund, V., Thorborg, S. S., Jespersgaard, C., Bjerrum, Ole Jannik, Dupontd, E., Nachman, G., Lykkesfeldt, Jens, Jensen, T. S. & Møller, L. B., 2018, In: Pain. 159, 6, p. 1012-1024 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  172. Published

    High-fat feeding induces mobilization of vitamin C in obese prone rats

    Tranberg, B., Hellgren, L. I., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2018, In: Research in Veterinary Science. 119, p. 167-169 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  173. Published

    Holder C-vitamin dine blodkar sunde?

    Skovsted, Gry Freja, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2018

    Research output: Other contributionNet publication - Internet publicationCommunication

  174. Published

    Liraglutide Decreases Hepatic Inflammation and Injury in Advanced Lean Non-Alcoholic Steatohepatitis

    Ipsen, David Højland, Rolin, B., Rakipovski, G., Skovsted, Gry Freja, Madsen, A., Kolstrup, S., Schou-Pedersen, A. M., Skat-Rørdam, Josephine, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 3, p. 704-713

    Research output: Contribution to journalJournal articlepeer-review

  175. Published

    Long term Westernized diet leads to region-specific changes in brain signaling mechanisms

    Hansen, S. N., Ipsen, David Højland, Schou-Pedersen, A. M., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Neuroscience Letters. 676, p. 85-91 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  176. Published

    Long-term Western diet fed apolipoprotein E-deficient rats exhibit only modest early atherosclerotic characteristics

    Rune, Ida, Rolin, B., Lykkesfeldt, Jens, Nielsen, Dennis Sandris, Krych, Lukasz, Kanter, J. E., Bornfeldt, K. E., Kihl, Pernille, Buschard, K., Josefsen, K., Fels, J. J., Mortensen, A., Christoffersen, B., Kirk, R. K. & Hansen, Axel Kornerup, 2018, In: Scientific Reports. 8, 1, 12 p., 5416.

    Research output: Contribution to journalJournal articlepeer-review

  177. Published

    Molecular mechanisms of hepatic lipid accumulation in non-alcoholic fatty liver disease

    Ipsen, David Højland, Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Cellular and Molecular Life Sciences. 75, 18, p. 3313-3327 15 p.

    Research output: Contribution to journalReviewpeer-review

  178. Published

    Oral insulin does not alter gut microbiota composition of NOD mice

    Kihl, Pernille, Krych, Lukasz, Buschard, K., Wesley, J. D., Kot, W., Hansen, Axel Kornerup, Nielsen, Dennis Sandris & von Herrath, M. G., 2018, In: Diabetes/Metabolism Research and Reviews. 34, 6, 9 p., e3010.

    Research output: Contribution to journalJournal articlepeer-review

  179. Published

    Role of pannexin and adenosine triphosphate (ATP) following myocardial ischemia/reperfusion

    Kristiansen, S. B., Skovsted, Gry Freja, Berchtold, L. A., Radziwon-Balicka, A., Dreisig, K., Edvinsson, L., Sheykhzade, Majid & Haanes, Kristian Agmund, 2018, In: Scandinavian Cardiovascular Journal. 52, 6, p. 340-343

    Research output: Contribution to journalJournal articlepeer-review

  180. Published

    SK channel inhibition did not increase short-term variability of the QT intervals in atrial tachypaced pigs with left ventricular dysfunction in contrast to the positive control dofetilide

    Citerni, C., Kirchhoff, J., Olsen, Lisbeth Høier, Gentilini, F., Forni, M., Zannoni, A., Edvardsson, N., Bentzen, B., Grunnet, M. & Diness, J., 2018, In: European Heart Journal. 39, S1, p. 809-809 P3811.

    Research output: Contribution to journalConference abstract in journalpeer-review

  181. Published

    Spatial Memory Dysfunction Induced by Vitamin C Deficiency Is Associated with Changes in Monoaminergic Neurotransmitters and Aberrant Synapse Formation

    Hansen, S. N., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2018, In: Antioxidants. 7, 7, p. 11 82.

    Research output: Contribution to journalJournal articlepeer-review

  182. Published

    The E3 ubiquitin ligase SMURF1 regulates cell-fate specification and outflow tract septation during mammalian heart development

    Rasmussen, K. K., Skat-Rørdam, Josephine, Andersen, P., Warzecha, C. B., Pye, M., Andersen, T. A., Ajbro, K. D., Bendsen, E., Narimatsu, M., Vilhardt, Frederik, Pedersen, Lotte Bang, Wrana, J. L., Anderson, R. H., Møllgård, Kjeld, Christensen, Søren Tvorup & Larsen, Lars Allan, 2018, In: Scientific Reports. 8, 1, 14 p., 9542.

    Research output: Contribution to journalJournal articlepeer-review

  183. Published

    The impact of exercise training and resveratrol supplementation on gut microbiota composition in high-fat diet fed mice

    Brandt, N., Kotowska, D., Kristensen, C. M., Olesen, J., Lützhøft, Ditte Olsen, Halling, J. F., Hansen, M., Al-Soud, W. A., Hansen, Lars Hestbjerg, Kiilerich, P. & Pilegaard, Henriette, 2018, In: Physiological Reports. 6, 20, p. 1-11 e13881.

    Research output: Contribution to journalJournal articlepeer-review

  184. Published

    Vasomotor dysfunction in human subcutaneous arteries exposed ex vivo to food-grade titanium dioxide

    Jensen, Ditte Marie, Skovsted, Gry Freja, Lykkesfeldt, Jens, Dreier, R., Berg, J. O., Jeppesen, J. L., Sheykhzade, Majid, Loft, Steffen & Møller, Peter, 2018, In: Food and Chemical Toxicology. 120, p. 321-327 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  185. 2017
  186. Published

    Acute Haemarthrosis in the Haemophilia A Rat Generates a Local and Systemic Proinflammatory Response

    Lovgren, K. M., Christensen, K. R., Majewski, W., Ostrup, O., Skov, Søren & Wiinberg, B., Nov 2017, In: Thrombosis and Haemostasis. 117, 11, p. 2092-2104

    Research output: Contribution to journalJournal articlepeer-review

  187. Published

    Hang on: An evaluation of the hemp rope as environmental enrichment in C57BL/6 mice

    Gjendal, K., Sørensen, Dorte Bratbo, Kiersgaard, M. K. & Ottesen, J. L., Nov 2017, In: Animal Welfare. 26, 4, p. 437-447 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  188. Published

    Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans: randomised, controlled trials

    Larsen, E. L., Cejvanovic, V., Kjær, L. K., Pedersen, M. T., Popik, S. D., Hansen, L. K., Andersen, Jon Thor Trærup, Solem, Espen Victor Jimenez, Broedbaek, K., Petersen, M., Weimann, A., Henriksen, T., Lykkesfeldt, Jens, Torp-Pedersen, C. & Poulsen, Henrik Enghusen, Aug 2017, In: British Journal of Clinical Pharmacology. 83, 8, p. 1643-1653

    Research output: Contribution to journalJournal articlepeer-review

  189. Published

    Toxicological Effects during and following Persistent Insulin-Induced Hypoglycaemia in Healthy Euglycaemic Rats

    Jensen, Vivi Flou Hjorth, Molck, A., Berthelsen, L. O., Alifrangis, L., Andersen, L., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., Jul 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 1, p. 53-66

    Research output: Contribution to journalJournal articlepeer-review

  190. Published

    Pasteurization Procedures for Donor Human Milk Affect Body Growth, Intestinal Structure, and Resistance against Bacterial Infections in Preterm Pigs

    Li, Y., Nguyen, Duc Ninh, de Waard, M., Christensen, Lars, Zhou, P., Jiang, Pingping, Sun, Jing, Bojesen, Anders Miki, Lauridsen, C., Lykkesfeldt, Jens, Dalsgaard, T. K., Bering, Stine Brandt & Sangild, Per Torp, Jun 2017, In: Journal of Nutrition. 147, 6, p. 1121-1130

    Research output: Contribution to journalJournal articlepeer-review

  191. Published

    35Sulphate incorporation assay as a new tool for measuring early cartilage degradation following blood exposure in vitro and in vivo in f8 ko rats

    Pulles, A. E., Christensen, K. R., Coeleveld, K., Kjelgaard-Hansen, M., Schutgens, R. E., Lafeber, F. P., Roepstorff, K. & Mastbergen, S. C., Apr 2017, In: Osteoarthritis and Cartilage. 25, S1, p. S156-S157

    Research output: Contribution to journalConference abstract in journalpeer-review

  192. Published

    Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ETB receptors via the protein kinase MEK-ERK1/2 signaling pathway in rat

    Skovsted, Gry Freja, Kruse, L. S., Berchtold, L. A., Grell, A., Warfvinge, K. & Edvinsson, L., 1 Mar 2017, In: PLOS ONE. 12, 3, 18 p., e0174119.

    Research output: Contribution to journalJournal articlepeer-review

  193. Published

    Endothelial dysfunction in the early postoperative period after major colon cancer surgery.

    Ekeløf, S., Larsen, M. H., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, Feb 2017, In: British Journal of Anaesthesia. 118, 2, p. 200-206

    Research output: Contribution to journalJournal articlepeer-review

  194. Published

    Plasma lipid oxidation predicts atherosclerotic status better than cholesterol in diabetic apolipoprotein E deficient mice

    Petersen, Karen Ekkelund, Lykkesfeldt, Jens, Raun, K. & Rakipovski, G., Jan 2017, In: Experimental Biology and Medicine (Maywood). 242, 1, p. 88-91

    Research output: Contribution to journalJournal articlepeer-review

  195. Published

    Visualization of haemophilic arthropathy in F8(-/-) rats by ultrasonography and micro-computed tomography

    Christensen, K. R., Roepstorff, K., Petersen, M., Wiinberg, B., Hansen, Axel Kornerup, Kjelgaard-Hansen, M. & Nielsen, L. N., Jan 2017, In: Haemophilia. 23, 1, 11 p., 152-162.

    Research output: Contribution to journalJournal articlepeer-review

  196. Published

    A porcine subcutaneous Staphylococcus aureus abscess model - a pilot study

    Nielsen, O. L., Larsen, M. N., Frees, Dorte, Pedersen, M. M., Skov, Søren & Olsen, Lisbeth Høier, 2017.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  197. Published

    Assessment of implantable infusion pumps for continuous infusion of human insulin in rats: potential for group housing

    Jensen, Vivi Flou Hjorth, Molck, A., Martensson, M., Strid, M. A., Chapman, M., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: Laboratory Animals. 51, 3, p. 273-283

    Research output: Contribution to journalJournal articlepeer-review

  198. Published

    Chronic Hyperinsulinaemic Hypoglycaemia in Rats Is Accompanied by Increased Body Weight, Hyperleptinaemia, and Decreased Neuronal Glucose Transporter Levels in the Brain

    Jensen, Vivi Flou Hjorth, Molck, A., Chapman, M., Alifrangis, L., Andersen, L., Lykkesfeldt, Jens & Bogh, I. B., 2017, In: International Journal of Endocrinology. 2017, 14 p., 7861236.

    Research output: Contribution to journalJournal articlepeer-review

  199. Published

    Effect of ES products from Anisakis (Nematoda: Anisakidae) on experimentally induced colitis in adult zebrafish

    Haarder, S., Kania, Per, Holm, T., Jørgensen, Louise von Gersdorff & Buchmann, Kurt, 2017, In: Parasite Immunology. 39, 10, 8 p., e12456.

    Research output: Contribution to journalJournal articlepeer-review

  200. Published

    Effect of High Inspiratory Oxygen Fraction on Endothelial Dysfunction in Healthy Volunteers: A Randomized Controlled Cross-over Pilot Study

    Larsen, M. H. H., Ekeløf, S., Kokotovic, D., Schou-Pedersen, A. M. V., Lykkesfeldt, Jens & Gögenur, I., 2017, In: Anesthesia and Analgesia. 125, 5, p. 1793–1796

    Research output: Contribution to journalJournal articlepeer-review

  201. Published

    Effect of early-life gut mucosal compromise on disease progression in NOD mice

    Bendtsen, K. M., Hansen, Camilla Hartmann Friis, Krych, Lukasz, Buschard, K., Farlov, H. & Hansen, Axel Kornerup, 2017, In: Comparative Medicine. 67, 5, p. 388-399 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  202. Published

    Gestational Protein Restriction in Wistar Rats; Effect of Taurine Supplementation on Properties of Newborn Skeletal Muscle

    Larsen, L. H., Sandø-Pedersen, S., Ørstrup, Laura Kofoed Hvidsten, Grunnet, N., Quistorff, B. & Mortensen, Ole Hartvig, 2017, Taurine 10. Lee, D-H., Schaffer, S. W., Park, E. & Kim, H. W. (eds.). Springer, Vol. 975. p. 413-433 21 p. (Advances in Experimental Medicine and Biology; No. 975).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  203. Published

    Immunological effects of reduced mucosal integrity in the early life of BALB/c mice

    Bendtsen, K. M. B., Hansen, Camilla Hartmann Friis, Krych, Lukasz, Skovgaard, K., Kot, W. P., Vogensen, Finn Kvist & Hansen, Axel Kornerup, 2017, In: PLOS ONE. 12, 5, 20 p., 0176662.

    Research output: Contribution to journalJournal articlepeer-review

  204. Published

    Markers of Oxidative Stress in Dogs with Myxomatous Mitral Valve Disease are Influenced by Sex, Neuter Status, and Serum Cholesterol Concentration

    Reimann, Maria Josefine, Haggstrom, J., Moller, J. E., Lykkesfeldt, Jens, Falk, T. & Olsen, Lisbeth Høier, 2017, In: Journal of Veterinary Internal Medicine. 31, 2, p. 295-302 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  205. Published

    Mitral Regurgitation Severity and Left Ventricular Systolic Dimension Predict Survival in Young Cavalier King Charles Spaniels

    Reimann, Maria Josefine, Moller, J. E., Haggstrom, J., Martinussen, Torben, Zatrazemi, S. S. C., Svanholm, L., Nielsen, L. B. M., Pedersen, H. D. & Olsen, Lisbeth Høier, 2017, In: Journal of Veterinary Internal Medicine. 31, 4, p. 1008-1016 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  206. Published

    Poor vitamin C status late in pregnancy is associated with increased risk of complications in type 1 diabetic women: A cross-sectional study

    Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, 2017, In: Nutrients. 9, 3, 9 p., 186.

    Research output: Contribution to journalJournal articlepeer-review

  207. Published

    Quality of life assessment in dogs and cats receiving chemotherapy: a review of current methods

    Vøls, Kåre Kryger, Heden, M. A., Kristensen, Annemarie T. & Sandøe, Peter, 2017, In: Veterinary and Comparative Oncology. 15, 3, p. 684–691 8 p.

    Research output: Contribution to journalReviewpeer-review

  208. Published

    The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers

    Nielsen, C. F., van Putten, S. M., Lund, I. K., Melander, M. C., Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Reckzeh, K., Christensen, K. R., Ingvarsen, S. Z., Gårdsvoll, Henrik, Jensen, K. E., Hamerlik, P., Engelholm, Lars Henning & Behrendt, Niels, 2017, In: OncoTarget. 8, 27, p. 44605-44624 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  209. Published

    Vitamin C deficiency reduces muscarinic receptor coronary artery vasoconstriction and plasma tetrahydrobiopterin concentration in guinea pigs

    Skovsted, Gry Freja, Tveden-Nyborg, Pernille, Lindblad, M. M., Hansen, S. N. & Lykkesfeldt, Jens, 2017, In: Nutrients. 9, 7, 14 p., 691.

    Research output: Contribution to journalJournal articlepeer-review

  210. Published

    Weekly ascorbic acid infusion in castration-resistant prostate cancer patients: A single-arm phase II trial

    Nielsen, Torben Kjær, Højgaard, M., Andersen, Jon Thor Trærup, Jørgensen, N. R., Zerahn, B., Kristensen, B., Henriksen, T., Lykkesfeldt, Jens, Mikines, K. J. & Poulsen, Henrik Enghusen, 2017, In: Translational Andrology and Urology. 6, 3, p. 517-528 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  211. 2016
  212. Published

    Comparison of two chemically-induced colitis-models in adult zebrafish, using optical projection tomography and novel transcriptional markers

    Haarder, S., Kania, Per, Holm, T., Otani, M. & Buchmann, Kurt, 20 Dec 2016, In: Open Journal of Immunology. 6, p. 154-180 27 p.

    Research output: Contribution to journalJournal articlepeer-review

  213. Published

    Dyslipidemia: Obese or Not Obese-That Is Not the Question

    Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Dec 2016, In: Current Obesity Reports. 5, 4, p. 405-412

    Research output: Contribution to journalReviewpeer-review

  214. Published

    Appropriate threshold levels of cardiac beat-to-beat variation in semi-automatic analysis of equine ECG recordings

    Madsen, M. F., Kanters, Jørgen K., Pedersen, P. J., Haugaard, M. M., Carstensen, Helena, Olsen, Lisbeth Høier & Buhl, Rikke, 28 Nov 2016, In: BMC Veterinary Research. 12, 10 p., 266.

    Research output: Contribution to journalJournal articlepeer-review

  215. Published

    Oxidative costs of reproduction in mouse strains selected for different levels of food intake and which differ in reproductive performance

    Jothery, A. H. A., Vaanholt, L. M., Mody, N., Arnous, A., Lykkesfeldt, Jens, Bunger, L., Hill, W. G., Mitchell, S. E., Allison, D. B. & Speakman, J. R., 14 Nov 2016, In: Scientific Reports. 6, 12 p., 36353 .

    Research output: Contribution to journalJournal articlepeer-review

  216. Published

    In vitro toxicity of cationic micelles and liposomes in cultured human hepatocyte (HepG2) and lung epithelial (A549) cell lines

    Roursgaard, Martin, Knudsen, K. B., Northeved, H., Persson, M., Christensen, T., Kumar, P. E. K., Permin, A., Andresen, T. L., Gjetting, T., Lykkesfeldt, Jens, Vesterdal, L. K., Loft, Steffen & Møller, Peter, Oct 2016, In: Toxicology in Vitro. 36, p. 164-171 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  217. Published

    Is Diabetes Associated with Lower Vitamin C Status in Pregnant Women? A Prospective Study

    Juhl, B., Lauszus, F. F. & Lykkesfeldt, Jens, Oct 2016, In: International Journal for Vitamin and Nutrition Research. 86, 5-6, p. 184-189

    Research output: Contribution to journalJournal articlepeer-review

  218. Published
  219. Published

    Cardiovascular health effects of oral and pulmonary exposure to multi-walled carbon nanotubes in ApoE-deficient mice

    Christophersen, D. V., Raun Jacobsen, N., Guerra Andersen, M. H., Connell, S. P., Barfod, K. K., Thomsen, Morten Bækgaard, Miller, M. R., Duffin, R., Lykkesfeldt, Jens, Vogel, U. B., Wallin, E. H. R., Loft, Steffen, Roursgaard, Martin & Møller, Peter, 14 Sep 2016, In: Toxicology. 371, p. 29-40 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  220. Published

    Joint bleeds increase the inhibitor response to human factor VIII in a rat model of severe haemophilia A

    Löfgren, Karin Maria, Søndergaard, H., Skov, Søren & Wiinberg, B., Sep 2016, In: Haemophilia. 22, 5, p. 772-779 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  221. Published

    Non-genetic risk factors in haemophilia A inhibitor management: the danger theory and the use of animal models

    Löfgren, Karin Maria, Søndergaard, H., Skov, Søren & Wiinberg, B., Sep 2016, In: Haemophilia. 22, 5, p. 657-666 10 p.

    Research output: Contribution to journalReviewpeer-review

  222. Published

    Rodent model choice has major impact on variability of standard preclinical readouts associated with diabetes and obesity research

    Jensen, Victoria Svop, Porsgaard, T., Lykkesfeldt, Jens & Hvid, H., 15 Aug 2016, In: American Journal of Translational Research. 8, 8, p. 3574-3584

    Research output: Contribution to journalJournal articlepeer-review

  223. Published

    Simultaneous quantification of monoamine neurotransmitters and their biogenic metabolites intracellularly and extracellularly in primary neuronal cell cultures and in sub-regions of guinea pig brain

    Schou-Pedersen, A. M. V., Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 15 Aug 2016, In: Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 1028, p. 222-230 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  224. Published

    Strategies for Using Plagiarism Software in the Screening of Incoming Journal Manuscripts: Recommendations Based on a Recent Literature Survey

    Lykkesfeldt, Jens, Aug 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 2, p. 161-164

    Research output: Contribution to journalJournal articlepeer-review

  225. Published

    Left Ventricular Function After Prolonged Exercise in Equine Endurance Athletes

    Flethøj, M., Schwarzwald, C. C., Haugaard, M. M., Carstensen, Helena, Kanters, Jørgen K., Olsen, Lisbeth Høier & Buhl, Rikke, Jul 2016, In: Journal of Veterinary Internal Medicine. 30, 4, p. 1260-1269 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  226. Published

    Maternal vitamin C deficiency does not reduce hippocampal volume and beta-tubulin III intensity in prenatal Guinea pigs

    Hansen, S. N., Schjoldager, J. G., Paidi, M. D., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, Jul 2016, In: Nutrition Research. 36, 7, p. 696-702

    Research output: Contribution to journalJournal articlepeer-review

  227. Published

    Establishment and use of surgical rat models for assessment of organ specific in vivo clearance

    Vestergaard, Bill, Jun 2016, In: Danish Medical Journal. 63, 6, 17 p., B5247.

    Research output: Contribution to journalReviewpeer-review

  228. Published

    Reduced Mechanical Stretch Induces Enhanced Endothelin B Receptor-mediated Contractility via Activation of Focal Adhesion Kinase and Extra Cellular-regulated Kinase 1/2 in Cerebral Arteries from Rat

    Spray, S., Rasmussen, M. N. P., Skovsted, Gry Freja, Warfvinge, K., Sheykhzade, Majid & Edvinsson, L., Jun 2016, In: Basic & Clinical Pharmacology & Toxicology. 119, 1, p. 68-77 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  229. Published

    The F8(-/-) rat as a model of hemophilic arthropathy

    Christensen, K. R., Roepstorff, K., Wiinberg, B., Hansen, Axel Kornerup, Tranholm, M., Nielsen, Lise Nikolic & Kjelgaard-Hansen, M., Jun 2016, In: Journal of Thrombosis and Haemostasis. 14, 6, p. 1216-1225 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  230. Published

    Changes in heart rate, arrhythmia frequency, and cardiac biomarker values in horses during recovery after a long-distance endurance ride

    Madsen, M. F., Kanters, Jørgen K., Haugaard, M. M., Pedersen, P. J., Carstensen, Helena, Balling, J. D., Olsen, Lisbeth Høier & Buhl, Rikke, 1 May 2016, In: Journal of the American Veterinary Medical Association. 248, 9, p. 1034-1042 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  231. Published

    The kidneys play a central role in the clearance of rhGH in rats

    Vestergaard, Bill, Thygesen, P., Kreilgaard, M., Fels, J. J., Lykkesfeldt, Jens & Agerso, H., 30 Apr 2016, In: European Journal of Pharmaceutical Sciences. 86, p. 29-33

    Research output: Contribution to journalJournal articlepeer-review

  232. Published

    Antibody response to recombinant human coagulation factor VIII in a new rat model of severe hemophilia A

    Löfgren, Karin Maria, Sondergaard, H., Skov, Søren, Weldingh, K. N., Tranholm, M. & Wiinberg, B., Apr 2016, In: Journal of Thrombosis and Haemostasis. 14, 4, p. 747-756

    Research output: Contribution to journalJournal articlepeer-review

  233. Published

    Increased serum C-reactive protein concentrations in dogs with congestive heart failure due to myxomatous mitral valve disease

    Reimann, Maria Josefine, Ljungvall, I., Hillstrom, A., Møller, J. E., Hagman, R., Falk, T., Hoglund, K., Haggstrom, J. & Olsen, Lisbeth Høier, Mar 2016, In: Veterinary Journal. 209, p. 113-118

    Research output: Contribution to journalJournal articlepeer-review

  234. Published

    Normal Weight Dyslipidemia: Is It All About the Liver?

    Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, Mar 2016, In: Obesity. 24, 3, p. 556-567 12 p.

    Research output: Contribution to journalReviewpeer-review

  235. Published

    Diet-induced dyslipidemia leads to nonalcoholic fatty liver disease and oxidative stress in guinea pigs

    Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland, Thiessen, T. S., Feldmann, L. D. B., Lindblad, M. M., Jensen, Henrik Elvang & Lykkesfeldt, Jens, 1 Feb 2016, In: Translational Research. 168, p. 146-160 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  236. Published

    Similar Adiponectin Levels in Obese Normotensive and Obese Hypertensive Men and No Vasorelaxant Effect of Adiponectin on Human Arteries

    Dreier, R., Asferg, C., Berg, J. O., Andersen, U. B., Flyvbjerg, A., Frystyk, J., Linneberg, Allan René, Jeppesen, J. L., Edvinsson, L. & Skovsted, Gry Freja, Feb 2016, In: Basic & Clinical Pharmacology & Toxicology. 118, 2, p. 128–135 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  237. Published

    Zebrafisken - en holistisk miljømodel

    Buchmann, Kurt, Kania, Per, Haarder, S. & Jørgensen, Louise von Gersdorff, 25 Jan 2016, Villum Fonden - Velux Fonden: årsskrift 2015. Søborg: Villum Fonden, p. 52-58 7 p. (Villum Fonden - Velux Fonden : årsskrift, Vol. 2015).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  238. Published

    Anti-RANKL treatment inhibits erosive joint destruction and lowers inflammation but has no effect on bone formation in the delayed-type hypersensitivity arthritis (DTHA) model

    Atkinson, S. M., Bleil, J., Maier, R., Kuehl, A. A., Thorn, M., Serikawa, K., Fox, B., Kruse, K., Haase, C., Skov, Søren, Nansen, A. & Syrbe, U., 23 Jan 2016, In: Arthritis Research & Therapy. 18, 12 p., 28.

    Research output: Contribution to journalJournal articlepeer-review

  239. Published

    Pulsatile Hyperglycaemia Induces Vascular Oxidative Stress and GLUT 1 Expression More Potently than Sustained Hyperglycaemia in Rats on High Fat Diet

    Rakipovski, G., Lykkesfeldt, Jens & Raun, K., 20 Jan 2016, In: P L o S One. 11, 1, e0147412.

    Research output: Contribution to journalJournal articlepeer-review

  240. Published

    Histopathological nerve and skeletal muscle changes in rats subjected to persistent insulin-induced hypoglycemia

    Jensen, Vivi Flou Hjorth, Mølck, A., Heydenreich, A., Jensen, K. J., Bertelsen, L. O., Alifrangis, L., Andersen, L., Søeborg, H., Chapman, M., Lykkesfeldt, Jens & Bøgh, I. B., Jan 2016, In: Toxicologic Pathology. 29, 1, p. 17-30 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  241. Published

    L-dehydroascorbic acid can substitute L-ascorbic acid as dietary vitamin C source in guinea pigs

    Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Redox Biology. 7, p. 8-13 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  242. Published

    Breeding Restrictions Decrease the Prevalence of Myxomatous Mitral Valve Disease in Cavalier King Charles Spaniels over an 8-to 10-Year Period

    Birkegård, A. C., Reimann, Maria Josefine, Martinussen, Torben, Haggstrom, J., Pedersen, H. D. & Olsen, Lisbeth Høier, 2016, In: Journal of Veterinary Internal Medicine. 30, 1, p. 63-68 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  243. Published

    Depletion of regulatory T cells leads to an exacerbation of delayedtype hypersensitivity arthritis in C57BL/6 mice that can be counteracted by IL-17 blockade

    Atkinson, S. M., Hoffmann, U., Bach, E., Danneskiold-Samsøe, Niels Banhos, Kristiansen, Karsten, Serikawa, K., Fox, B., Kruse, K., Haase, C., Skov, Søren & Nansen, A., 2016, In: Disease Models & Mechanisms. 9, p. 427-440 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  244. Published

    Does Glucagon-like Peptide-1 Ameliorate Oxidative Stress in Diabetes? Evidence Based on Experimental and Clinical Studies

    Petersen, Karen Ekkelund, Rakipovski, G., Raun, K. & Lykkesfeldt, Jens, 2016, In: Current Diabetes Reviews. 12, 4, p. 331-358 28 p.

    Research output: Contribution to journalReviewpeer-review

  245. Published

    Gall midges (Diptera: Cecidomyiidae) new to the Danish fauna

    Haarder, S., Bruun, Hans Henrik, Harris, K. M. & Skuhravá, M., 2016, In: Entomologisk Tidskrift. 137, p. 79-98 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  246. Published

    High-fat but not sucrose intake is essential for induction of dyslipidemia and non-alcoholic steatohepatitis in guinea pigs

    Ipsen, David Højland, Tveden-Nyborg, Pernille, Rolin, B., Rakipovski, G., Beck, M., Mortensen, L. W., Færk, L., Heegaard, P. M. H., Møller, Peter & Lykkesfeldt, Jens, 2016, In: Nutrition & Metabolism. 13, p. 51

    Research output: Contribution to journalJournal articlepeer-review

  247. Published

    Modulating the gut microbiota improves glucose tolerance, lipoprotein profile and atherosclerotic plaque development in ApoE-deficient mice

    Rune, Ida, Rolin, B., Larsen, C. S., Nielsen, Dennis Sandris, Kanter, J. E., Bornfeldt, K. E., Lykkesfeldt, Jens, Buschard, K., Kirk, R. K., Christoffersen, B., Fels, J. J., Josefsen, K., Kihl, Pernille & Hansen, Axel Kornerup, 2016, In: P L o S One. 11, 1, 16 p., e0146439.

    Research output: Contribution to journalJournal articlepeer-review

  248. Published

    Penetration of antimicrobials to pulmonary epithelial lining fluid and muscle and impact of drug physicochemical properties determined by microdialysis

    Rottbøll, Lisa Amanda Holm & Friis, C., 2016, In: Journal of Pharmacological and Toxicological Methods. 78, p. 58-65 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  249. Published

    Simvastatin and oxidative stress in humans: A randomized, double-blinded, placebo-controlled clinical trial

    Rasmussen, S. T., Andersen, Jon Thor Trærup, Nielsen, T. K., Cejvanovic, V., Petersen, K. M., Henriksen, T., Weimann, A., Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2016, In: Redox Biology. 9, p. 32-38

    Research output: Contribution to journalJournal articlepeer-review

  250. Published

    Spontaneous bleeds in the elbows of F8-/- rats cause development of blood-induced joint disease closely resembling human hemophilic arthropathy

    Thyme, A. P., Vøls, Kåre Kryger, Christensen, K. R., Löfgren, Karin Maria, Wiinberg, B., Kvist, P. H., Kjelgaard-Hansen, M., Roepstorff, K., Nielsen, Lise Nikolic & Tranholm, M., 2016.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  251. Published

    Vitaminer til hjernen

    Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2016, In: Aktuel Naturvidenskab. 2016, 4, p. 8-11 4 p.

    Research output: Contribution to journalJournal article

  252. 2015
  253. Published

    Treatment with anti-C5aR mAb leads to early-onset clinical and mechanistic effects in the murine delayed-type hypersensitivity arthritis model

    Atkinson, S. M., Nansen, A., Usher, P. A., Sondergaard, B., Mackay, C. R., Friedrichsen, B., Chang, C., Tang, R., Skov, Søren, Haase, C. & Hornum, L., Nov 2015, In: Autoimmunity. 48, 7, p. 460-470 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  254. Published

    Thick methacrylate sections devoid of lost caps simplify stereological quantifications based on the optical fractionator design

    Andersen, S. H., Lykkesfeldt, Jens & Larsen, J. O., 15 Sep 2015, In: Anatomical Record. 298, 12, p. 2141-2150 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  255. Published

    Calcium signaling in coronary artery after reperfusion damage in rat model of acute myocardial infarct

    Kristiansen, S. B., Skovsted, Gry Freja, Sheykhzade, Majid & Edvinsson, L., Sep 2015, In: Acta Physiologica (Print). 215, Supplement, p. 3-4 7.

    Research output: Contribution to journalConference abstract in journalpeer-review

  256. Published

    Antimicrobial drug penetration into the pulmonary epithelial lining fluid and muscle measured by microdialysis in anesthetized pigs

    Rottbøll, Lisa Amanda Holm & Friis, C., Jul 2015, In: Journal of Veterinary Pharmacology and Therapeutics. 38, S1, p. 89 1 p., 1.12.

    Research output: Contribution to journalConference abstract in journalpeer-review

  257. Published

    Chronic dyslipidemia induces fatty liver disease in Guinea pigs

    Tveden-Nyborg, Pernille, Birck, M. M., Ipsen, David Højland & Lykkesfeldt, Jens, Jul 2015, In: Atherosclerosis. 241, 1, p. e119-e120 2 p.

    Research output: Contribution to journalConference abstract in journalpeer-review

  258. Published

    Vascular gene expression in diet-induced atherosclerotic Gottingen minipigs

    Christensen, Liv von Voss, Skovgaard, K., Ludvigsen, T. P., Kirk, R. K., Christoffersen, B. O., Pedersen, H. D., Heegaard, P. M. & Olsen, Lisbeth Høier, Jul 2015, In: Atherosclerosis. 241, 1, p. E85-E85 1 p.

    Research output: Contribution to journalConference abstract in journalpeer-review

  259. Published

    The Zebra Fish IBD Model Assessed By Novel Probe Based TagMan Assays

    Kania, Per, Buchmann, Kurt & Haarder, S., 29 Jun 2015.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  260. Published

    Lower limb ischaemia and reperfusion injury in healthy volunteers measured by oxidative and inflammatory biomarkers

    Halladin, N. L., Busch, S. V. E., Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 10 Apr 2015, In: Perfusion. 30, 1, p. 64-70 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  261. Published

    Alpha-smooth muscle actin and serotonin receptors 2A and 2B in dogs with myxomatous mitral valve disease

    Cremer, Signe Emilie, Moesgaard, S. G., Rasmussen, C. E., Zois, N. E., Falk, T., Reimann, Maria Josefine, Cirera, Susanna, Aupperle, H., Oyama, M. A. & Olsen, Lisbeth Høier, 19 Mar 2015, In: Research in Veterinary Science. 100, p. 197-206 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  262. Published

    High-resolution gene expression profiling using RNA sequencing in patients with inflammatory bowel disease and in mouse models of colitis

    Holgersen, K., Kutlu, B., Fox, B., Serikawa, K., Lord, J., Hansen, Axel Kornerup & Holm, T. L., Mar 2015, In: Journal of Crohn's and Colitis (JCC). 9, 6, p. 492-506 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  263. Published

    The effect of short-term, high-dose oral N-acetylcysteine treatment on oxidative stress markers in cystic fibrosis patients with chronic P. aeruginosa infection: a pilot study

    Skov, M., Pressler, T., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen, Jensen, Peter Østrup, Johansen, Helle Krogh, Qvist, T., Kræmer, D., Høiby, Niels & Ciofu, Oana, Mar 2015, In: Journal of Cystic Fibrosis. 14, 2, p. 211-218 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  264. Published

    In vivo toxicity of cationic micelles and liposomes

    Knudsen, K. B., Northeved, H., Kumar Ek, P., Permin, A., Gjetting, T., Andresen, T. L., Larsen, S., Wegener, K. M., Lykkesfeldt, Jens, Jantzen, K., Loft, Steffen, Møller, Peter & Roursgaard, Martin, 25 Feb 2015, In: Nanomedicine: Nanotechnology, Biology and Medicine. 11, 2, p. 467-477 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  265. Published

    IL-33 promotes GATA-3 polarization of gut-derived T cells in experimental and ulcerative colitis

    Seidelin, Jakob Benedict, Coskun, M., Kvist, P. H., Holm, T. L., Holgersen, K. & Nielsen, Ole Haagen, Feb 2015, In: Journal of Gastroenterology. 50, 2, p. 180-190 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  266. Published

    Piroxicam treatment augments bone abnormalities in interleukin-10 knockout mice

    Holgersen, K., Dobie, R., Farquharson, C., Van't Hof, R., Ahmed, S. F., Hansen, Axel Kornerup & Lindebo Holm, T., Feb 2015, In: Inflammatory Bowel Diseases. 21, 2, p. 257-266 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  267. Published

    Asymmetric dimethylarginine in somatically healthy schizophrenia patients treated with atypical antipsychotics: a case-control study

    Jørgensen, Anders, Knorr, Ulla Benedichte Søsted, Soendergaard, M. G., Lykkesfeldt, Jens, Fink-Jensen, Anders, Poulsen, Henrik Enghusen, Jørgensen, Martin Balslev, Olsen, N. V. & Staalsø, J. M., 2015, In: B M C Psychiatry. 15, 8 p., 67.

    Research output: Contribution to journalJournal articlepeer-review

  268. Published

    Colonic lesions, cytokine profiles, and gut microbiota in plasminogen-deficient mice

    Vestergaard, Bill, Krych, Lukasz, Lund, L. R., Jørgensen, B. M. P., Hansen, Lars Hestbjerg, Jensen, Henrik Elvang, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2015, In: Comparative Medicine. 65, 5, p. 382-397 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  269. Published

    Controlled exposure to particulate matter from urban street air is associated with decreased vasodilation and heart rate variability in overweight and older adults

    Hemmingsen, J. G., Rissler, J., Lykkesfeldt, Jens, Sallsten, G., Kristiansen, J., Møller, Peter & Loft, Steffen, 2015, In: Particle and Fibre Toxicology. 12, 10 p., 6.

    Research output: Contribution to journalJournal articlepeer-review

  270. Published

    Dietary magnesium deficiency affects gut microbiota and anxiety-like behaviour in C57BL/6N mice

    Jørgensen, B. M. P., Winther, G., Kihl, Pernille, Nielsen, Dennis Sandris, Wegener, G., Hansen, Axel Kornerup & Sørensen, Dorte Bratbo, 2015, In: Acta Neuropsychiatrica (Print). 27, 5, p. 307-311 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  271. Published

    Dietary magnesium deficiency alters gut microbiota and leads to depressive-like behaviour

    Winther, G., Jørgensen, B. M. P., Elfving, B., Nielsen, Dennis Sandris, Kihl, Pernille, Lund, S., Sørensen, Dorte Bratbo & Wegener, G., 2015, In: Acta Neuropsychiatrica (Print). 27, 3, p. 168-176 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  272. Published

    Distribution of vitamin C is tissue specific with early saturation of the brain and adrenal glands following differential oral dose regimens in guinea pigs

    Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2015, In: British Journal of Nutrition. 113, 10, p. 1539-1549 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  273. Published

    Elimination of ascorbic acid after high-dose infusion in prostate cancer patients: a pharmacokinetic evaluation

    Nielsen, Torben Kjær, Højgaard, M., Andersen, J. T. T., Poulsen, Henrik Enghusen, Lykkesfeldt, Jens & Mikines, K. J., 2015, In: Basic & Clinical Pharmacology & Toxicology. 116, 4, p. 343-348 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  274. Published

    Endothelin-1 and endothelin-3 regulate endothelin receptor expression in rat coronary arteries

    Skovsted, Gry Freja, Kilic, S. & Edvinsson, L., 2015, In: Basic & Clinical Pharmacology & Toxicology Online. 117, 5, p. 297-305 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  275. Published

    Første fund af Aphanogmus hibernicus (Hymenoptera: Ceraphronidae) udenfor Irland.

    Haarder, S., 2015, In: Entomologiske Meddelelser. 83, 1, p. 31-32 2 p.

    Research output: Contribution to journalJournal article

  276. Published

    Göttingen minipig model of diet-induced atherosclerosis: influence of mild streptozotocin-induced diabetes on lesion severity and markers of inflammation evaluated in obese, obese and diabetic, and lean control animals

    Ludvigsen, Trine Pagh, Kirk, R. K., Christoffersen, B. Ø., Pedersen, H. D., Martinussen, Torben, Kildegaard, J., Heegaard, P. M. H., Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2015, In: Journal of Translational Medicine. 13, 12 p., 312.

    Research output: Contribution to journalJournal articlepeer-review

  277. Published

    Intrabronchial microdialysis: effects of probe localization on tissue trauma and drug penetration into the pulmonary epithelial lining fluid

    Rottbøll, Lisa Amanda Holm, Skovgaard, K., Barington, Kristiane, Jensen, Henrik Elvang & Friis, C., 2015, In: Basic & Clinical Pharmacology & Toxicology. 117, 4, p. 242-250 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  278. Published

    Maternal vitamin C deficiency during pregnancy results in transient fetal and placental growth retardation in guinea pigs: [Plus] erratum

    Schjoldager, J. G., Paidi, M. D., Lindblad, M. M., Birck, M. M., Kjærgaard, A. B., Dantzer, V., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2015, In: European Journal of Nutrition. 54, 4, p. 667-676 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  279. Published

    Plasma and serum serotonin concentrations and surface-bound platelet serotonin expression in Cavalier King Charles Spaniels with myxomatous mitral valve disease

    Cremer, Signe Emilie, Kristensen, Annemarie T., Reimann, Maria Josefine, Eriksen, N. B., Petersen, S. F., Marschner, C. B., Tarnow, I., Oyama, M. A. & Olsen, Lisbeth Høier, 2015, In: American Journal of Veterinary Research. 76, 6, p. 520-531 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  280. Published

    Randall Selitto pressure algometry for assessment of bone-related pain in rats

    Falk, S., Ipsen, David Højland, Appel, C. K., Ugarak, A., Durup, D., Dickenson, A. H. & Heegaard, Anne-Marie, 2015, In: European Journal of Pain. 19, 3, p. 305-312 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  281. Published

    Serotonin markers show altered transcription levels in an experimental pig model of mitral regurgitation

    Cremer, Signe Emilie, Zois, N. E., Moesgaard, S. G., Ravn, N., Cirera, Susanna, Honge, J. L., Smerup, M. H., Hasenkam, J. M., Sloth, E., Leifsson, Páll S., Falk, B. T., Oyama, M. A., Orton, C., Martinussen, Torben & Olsen, Lisbeth Høier, 2015, In: The Veterinary Journal. 203, 2, p. 192-198 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  282. Published

    The influence of the young microbiome on inflammatory diseases - lessons from animal studies

    Bendtsen, K. M. B., Fisker, L., Hansen, Axel Kornerup, Hansen, Camilla Hartmann Friis & Nielsen, Dennis Sandris, 2015, In: Birth Defects Research. Part C: Embryo Today Reviews (Print). 105, 4, p. 278-295 18 p.

    Research output: Contribution to journalReviewpeer-review

  283. Published

    Third-stage nematode larvae of Contracaecum osculatum from Baltic cod (Gadus morhua) elicit eosinophilic granulomatous reactions when penetrating the stomach mucosa of pigs

    Strøm, S. B., Haarder, S., Korbut, R., Mejer, H., Thamsborg, Stig Milan, Kania, Per & Buchmann, Kurt, 2015, In: Parasitology Research. 114, 3, p. 1217-1220 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  284. 2014
  285. Published

    Zebra fish as a model for inflammatory bowel disease (IBD): preliminary results

    Haarder, S., Kania, Per, Hyttel, P., Lindebo Holm, T. & Buchmann, Kurt, Nov 2014.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  286. Published

    An improved method for lifting and transporting anesthetized pigs within an animal facility

    Schumacher-Petersen, Camilla, Hammelev, Karsten Pharao & Flescher, Jens, Jul 2014, In: Lab Animal. 43, 7, p. 237-41 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  287. Published

    Positive charge, negative effect: the impact of cationic nanoparticles in the brain

    Møller, Peter & Lykkesfeldt, Jens, Jul 2014, In: Nanomedicine. 9, 10, p. 1441-3 3 p.

    Research output: Contribution to journalEditorialpeer-review

  288. Published

    Validation of Piroxicam-Accelerated Colitis in the Interleukin-10 Knock out Mouse - a Preclinical Model Mimicking Human Inflammatory Bowel Disease

    Holgersen, K., Kvist, P. H., Hansen, Axel Kornerup & Holm, T. L., May 2014.

    Research output: Contribution to conferencePosterResearchpeer-review

  289. Published

    Potassium and calcium channel gene expression in small arteries in porcine and rat models of diet-induced obesity (Poster)

    Jensen, Lars Jørn, Salomonsson, M., Sorensen, Charlotte Mehlin, von Holstein-Rathlou, Niels-Henrik, Pedersen, H. D., Christoffersen, B. Ø., Olsen, Lisbeth Høier & Ludvigsen, Trine Pagh, 27 Apr 2014, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28, Supplement 1, 1 p., 676.4.

    Research output: Contribution to journalConference abstract in journalpeer-review

  290. Published

    Advances in targeted delivery of small interfering RNA using simple bioconjugates

    Nielsen, C., Kjems, J., Sørensen, K. R., Engelholm, Lars Henning & Behrendt, Niels, 2014, In: Expert Opinion on Drug Delivery. 11, 5, p. 791-822 32 p.

    Research output: Contribution to journalReviewpeer-review

  291. Published

    An oxazolone zebrafish model for inflammatory bowel disease (IBD): preliminary results

    Haarder, S., Kania, Per, Hyttel, P., Lindebo Holm, T. & Buchmann, Kurt, 2014.

    Research output: Contribution to conferencePosterResearchpeer-review

  292. Published

    Antioxidant supplementation for lung disease in cystic fibrosis

    Ciofu, Oana & Lykkesfeldt, Jens, 2014, In: The Cochrane library. 2014, 8, 87 p., CD007020.

    Research output: Contribution to journalJournal articlepeer-review

  293. Published

    Applicability of chronic inflammation models for mechanistic in vivo studies

    Christensen, A. D., 2014

    Research output: Book/ReportPh.D. thesis

  294. Published

    Associations between N-terminal procollagen type III, fibrosis and echocardiographic indices in dogs that died due to myxomatous mitral valve disease

    Hezzell, M. J., Falk, B. T., Olsen, Lisbeth Høier, Boswood, A. & Elliott, J., 2014, In: Journal of Veterinary Cardiology. 16, 4, p. 257-264 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  295. Published

    Biodistribution of rhodamine B fluorescence-labeled cationic nanoparticles in rats

    Knudsen, K. B., Northeved, H., Gjetting, T., Permin, A., Andresen, T. L., Wegener, K. M., Rye Lam, H. & Lykkesfeldt, Jens, 2014, In: Journal of Nanoparticle Research. 16, 1, 11 p., 2221.

    Research output: Contribution to journalJournal articlepeer-review

  296. Published

    Biopterin status in dogs with myxomatous mitral valve disease is associated with disease severity and cardiovascular risk factors

    Reimann, Maria Josefine, Häggström, J., Mortensen, A., Lykkesfeldt, Jens, Møller, J. E., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1520-1526 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  297. Published

    Canine mitral valve disease: From genetics through screening programs, to practical breeding advice

    Häggström, J., Swift, S. & Olsen, Lisbeth Høier, 2014.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  298. Published

    Cardiovascular of Inflammatory Disease Models: In vivo imaging, Pathology and Pharmacology

    Olsen, Lisbeth Høier, Nielsen, O. L., Hunter, I., Falk, B. T., Cremer, Signe Emilie, Ludvigsen, Trine Pagh, Reimann, Maria Josefine, Olsen, H. G., Nielsen, K. M., Laursen, H., Kronborg, S. & Kjempff, C. T., 2014.

    Research output: Contribution to conferencePosterCommunication

  299. Published

    Characterisation of enterocolitis in the piroxicam-accelerated interleukin-10 knock out mouse: a model mimicking inflammatory bowel disease

    Holgersen, K., Kvist, P. H., Markholst, H., Hansen, Axel Kornerup & Holm, T. L., 2014, In: Journal of Crohn's and Colitis. 8, 2, p. 147-160 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  300. Published

    Chronic vitamin C deficiency promotes redox imbalance in the brain but does not alter sodium-dependent vitamin C transporter 2 expression

    Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrients. 6, 5, p. 1809-1822 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  301. Published

    Development and Characterization of an Atherosclerotic Minipig Model

    Ludvigsen, Trine Pagh, 2014, Copenhagen University.

    Research output: Book/ReportPh.D. thesis

  302. Published

    Development of left ventricular hypertrophy in a novel porcine model of mitral regurgitation

    Ravn, N., Zois, N. E., Moesgaard, S. G., Hønge, J. L., Smerup, M. H., Hasenkam, J. M., Sloth, E., Cremer, Signe Emilie & Olsen, Lisbeth Høier, 2014, In: Scandinavian Cardiovascular Journal. 48, 3, p. 189-195 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  303. Published

    Differential toxicological response to positively and negatively charged nanoparticles in the rat brain

    Knudsen, K. B., Northeved, H., Ek, P. K., Permin, A., Andresen, T. L., Larsen, S., Wegener, K. M., Lam, H. R. & Lykkesfeldt, Jens, 2014, In: Nanotoxicology. 8, 7, p. 764-774 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  304. Published

    Does vitamin C deficiency affect cognitive development and function?

    Hansen, S. N., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 9, p. 3818-3846 29 p.

    Research output: Contribution to journalJournal articlepeer-review

  305. Published

    Does vitamin C deficiency promote fatty liver disease development?

    Ipsen, David Højland, Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2014, In: Nutrients. 6, 12, p. 5473-5499 27 p.

    Research output: Contribution to journalReviewpeer-review

  306. Published

    Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies

    Mortensen, A. & Lykkesfeldt, Jens, 2014, In: Nitric Oxide: Biology and Chemistry. 36, p. 51-57 7 p.

    Research output: Contribution to journalReviewpeer-review

  307. Published

    Echocardiographic assessment of left ventricular function in mitral regurgitation: is the dog a useful model of man?

    Zois, N. E., Pedersen, H. D., Häggström, J. & Olsen, Lisbeth Høier, 2014, In: Cardiovascular Endocrinology. 3, 1, p. 9-14 6 p.

    Research output: Contribution to journalReviewpeer-review

  308. Published

    Effect of insulin-induced hypoglycaemia on the central nervous system: evidence from experimental studies

    Jensen, Vivi Flou Hjorth, Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 3, p. 123-150 28 p.

    Research output: Contribution to journalJournal articlepeer-review

  309. Published

    Effect of insulin-induced hypoglycaemia on the peripheral nervous system: focus on adaptive mechanisms, pathogenesis and histopathological changes

    Jensen, Vivi Flou Hjorth, Mølck, A., Bøgh, I. B. & Lykkesfeldt, Jens, 2014, In: Journal of Neuroendocrinology. 26, 8, p. 482-496 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  310. Published

    Effect of melatonin on human nighttime endotoxaemia: randomized, double-blinded, cross-over study

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, 6, p. 1057-1063 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  311. Published

    Feasibility of simultaneous PET/MR in diet-induced atherosclerotic minipig: a pilot study for translational imaging

    Pedersen, S. F., Ludvigsen, Trine Pagh, Johannesen, Helle Hjorth, Löfgren, J., Ripa, Rasmus Sejersten, Hansen, Adam Espe, Ettrup, A. J., Christoffersen, B. Ø., Pedersen, H. D., Olsen, Lisbeth Høier, Højgaard, Liselotte & Kjær, Andreas, 2014, In: American Journal of Nuclear Medicine and Molecular Imaging. 4, 5, p. 448-58 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  312. Published

    Functional network analysis of obese and lean Göttingen minipigs elucidates changes in oxidative and inflammatory networks in obese pigs

    Boonen, H. C. M., Moesgaard, S. G., Birck, M. M., Christoffersen, B. Ø., Cirera, Susanna, Heegaard, P. M. H., Højbøge, T. R., Jensen, Lars Jørn, Mortensen, A., Olsen, Lisbeth Høier, Sheykhzade, Majid, Tang, J. & Lykkesfeldt, Jens, 2014, In: Pflügers ARchiv (European Journal of Physiology). 466, 12, p. 2167-2176 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  313. Published

    High-fat feeding increases hepatic vitamin C synthesis and its circulatory mobilization in mice

    Christensen, B. T., Hansen, Axel Kornerup & Lykkesfeldt, Jens, 2014, In: European Journal of Nutrition. 53, 6, p. 1441-1444 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  314. Published

    High-level serotonin binding in subpopulation of highly activated platelets in cavalier King charles spaniels with myxomatous mitral valve disease

    Cremer, Signe Emilie, Kristensen, Annemarie T., Reimann, Maria Josefine, Eriksen, N. B., Petersen, S. F., Marschner, C. B., Tarnow, I., Oyama, M. A. & Olsen, Lisbeth Høier, 2014.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  315. Published

    High-level serotonin-binding in subpopulation of highly-activated platelets in Cavalier King Charles Spaniels with myxomateous valve disease

    Cremer, S. E., Kristensen, Annemarie T., Reimann, M. J., Eriksen, N. B., Petersen, S. F., Marschner, C. B., Tarnow, I., Oyama, M. A. & Olsen, Lisbeth Høier, 2014. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  316. Published

    Holter monitoring of small breed dogs with advanced myxomatous mitral valve disease with and without a history of syncope

    Rasmussen, C. E., Falk, B. T., Petrič, A. D., Schaldemose, M., Zois, N. E., Moesgaard, S. G., Åblad, B., Nielsen, H. Y., Ljungvall, I., Höglund, K., Häggström, J., Pedersen, H. D., Bland, J. M. & Olsen, Lisbeth Høier, 2014, In: Journal of Veterinary Internal Medicine. 28, 2, p. 363-370 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  317. Published

    In vivo vitamin C deficiency in guinea pigs increases ascorbate transporters in liver but not kidney and brain

    Søgaard, D., Lindblad, M. M., Paidi, M. D., Andersen, S. H., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Nutrition Research. 34, 7, p. 639-645 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  318. Published

    Increased Contracaecum osculatum infection in Baltic cod (Gadus morhua) livers (1982-2012) associated with increasing grey seal (Halichoerus gryphus) populations.

    Haarder, S., Kania, Per, Galatius, A. & Buchmann, Kurt, 2014, In: Journal of Wildlife Diseases. 50, 3, p. 537-543 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  319. Published

    Matrix metalloproteinases (MMPs), tissue inhibitors of metalloproteinases (TIMPs) and transforming growth factor-β (TGF-β) in advanced canine myxomatous mitral valve disease

    Moesgaard, S. G., Aupperle, H., Rajamäki, M. M., Falk, T., Rasmussen, C. E., Zois, N. E. & Olsen, Lisbeth Høier, 2014, In: Research in Veterinary Science. 97, 3, p. 560-567 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  320. Published

    Melatonin does not affect oxidative/inflammatory biomarkers in a closed-chest porcine model of acute myocardial infarction

    Halladin, N. L., Busch, S. V. E., Jensen, S. E., Aarøe, J., Kjærgaard, B., Heegaard, P. M. H., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: In Vivo. 28, p. 483-488 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  321. Published

    Melatonin suppresses markers of inflammation and oxidative damage in a human daytime endotoxemia model

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, Ismail, 2014, In: Journal of Critical Care. 29, 1, p. 184.e9-184.e13 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  322. Published

    Microdialysis as a tool for drug quantification in the bronchioles of anaesthetized pigs

    Rottbøll, Lisa Amanda Holm & Friis, C., 2014, In: Basic & Clinical Pharmacology & Toxicology Online. 114, 3, p. 226-232 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  323. Published

    Natriuretic peptides in cardiometabolic regulation and disease

    Zois, N. E., Bartels, E. D., Hunter, I., Kousholt, B. S., Olsen, Lisbeth Høier & Gøtze, J. P., 2014, In: Nature Reviews Cardiology. 11, 7, p. 403-412 10 p.

    Research output: Contribution to journalReviewpeer-review

  324. Published

    Neonatal Vitamin C Deficiency and Impaired Brain Development: A Dose-response Study

    Andersen, S. H., 2014, Copenhagen University.

    Research output: Book/ReportPh.D. thesis

  325. Published

    New records of gall midges (Diptera: Cecidomyiidae) from Denmark

    Bruun, Hans Henrik, Haarder, S., Jørgensen, J. & Skuhravá, M., 2014, In: Entomologiske Meddelelser. 82, 1, p. 25-37 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  326. Published

    Non-terminal blood sampling techniques in Guinea pigs

    Birck, M. M., Tveden-Nyborg, Pernille, Lindblad, M. M. & Lykkesfeldt, Jens, 2014, In: Journal of Visualized Experiments. 92, e51982.

    Research output: Contribution to journalJournal articlepeer-review

  327. Published

    Noninvasive assessment of pulse-wave velocity and flow-mediated vasodilation in anesthetized Göttingen minipigs

    Ludvigsen, Trine Pagh, Wiinberg, N., Jensen, C. J., Callesen, A. T., Andersen, R. W., Jørgensen, A. S. H., Christoffersen, B. Ø., Pedersen, H. D., Moesgaard, S. G. & Olsen, Lisbeth Høier, 2014, In: Comparative Medicine. 64, 6, p. 471-477 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  328. Published

    Pig models for the human heart failure syndrome

    Hunter, I., Terzic, D., Zois, N. E., Olsen, Lisbeth Høier & Gøtze, J. P., 2014, In: Cardiovascular Endocrinology. 3, 1, p. 15-18 4 p.

    Research output: Contribution to journalReviewpeer-review

  329. Published

    Predictive validity and immune cell involvement in the pathogenesis of piroxicam-accelerated colitis in interleukin-10 knockout mice

    Holgersen, K., Kvist, P. H., Hansen, Axel Kornerup & Holm, T. L., 2014, In: International Immunopharmacology. 21, 1, p. 137-147 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  330. Published

    Prenatal vitamin C deficiency results in differential levels of oxidative stress during late gestation in foetal guinea pig brains

    Paidi, M. D., Schjoldager, J. G., Lykkesfeldt, Jens & Tveden-Nyborg, Pernille, 2014, In: Redox Biology. 2, p. 361-367 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  331. Published

    Pronounced inflammatory response to endotoxaemia during nighttime: a randomised cross-over trial

    Alamili, M., Bendtzen, K., Lykkesfeldt, Jens, Rosenberg, Jacob & Gögenur, I., 2014, In: PloS one. 9, 1, 7 p., e87413.

    Research output: Contribution to journalJournal articlepeer-review

  332. Published

    R-R interval variations influence the degree of mitral regurgitation in dogs with myxomatous mitral valve disease

    Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2014, In: The Veterinary Journal. 199, 3, p. 348-354 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  333. Published

    Serotonin concentration is elevated in platelet-rich plasma and left ventricular myocardial and mitral valve leaflet tissue in dogs with myxomatous mitral valve disease

    Cremer, Signe Emilie, Singletary, G. E., Olsen, Lisbeth Høier, Wallace, K., Häggström, J., Ljungvall, I., Höglund, K., Reynolds, C. A., Pizzinat, N. & Oyama, M. A., 2014.

    Research output: Contribution to conferenceConference abstract for conferenceCommunication

  334. Published

    Serotonin concentrations in platelets, plasma, mitral valve leaflet, and left ventricular myocardial tissue in dogs with myxomatous mitral valve disease

    Cremer, Signe Emilie, Singletary, G. E., Olsen, Lisbeth Høier, Wallace, K., Häggström, J., Ljungvall, I., Höglund, K., Reynolds, C. A., Pizzinat, N. & Oyama, M. A., 2014, In: Journal of veterinary internal medicine / American College of Veterinary Internal Medicine. 28, 5, p. 1534-1540 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  335. Published

    Strong association between activated valvular interstitial cells and histopathological lesions in porcine model of induced mitral regurgitation

    Cremer, Signe Emilie, Zois, N. E., Moesgaard, S. G., Ravn, N., Cirera, Susanna, Honge, J. L., Smerup, M. H., Hasenkam, J. M., Sloth, E., Leifsson, Páll S., Falk, B. T., Oyama, M. A., Orton, C., Martinussen, Torben & Olsen, Lisbeth Høier, 2014, In: International Journal of Cardiology. 174, 2, p. 443-446 4 p.

    Research output: Contribution to journalLetterpeer-review

  336. Published

    The kidneys play an important role in the clearance of rFVIIa in rats

    Vestergaard, Bill, Appa, R. S., Lykkesfeldt, Jens & Agersø, H., 2014, In: Thrombosis Research. 133, 6, p. 1124-1129 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  337. Published

    The role of neutrophils and G-CSF in DNFB-induced contact hypersensitivity in mice

    Christensen, A. D., Skov, Søren & Haase, C., 2014, In: Immunity, Inflammation and Disease. 2, 1, p. 21-34 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  338. Published

    Transfer of gut microbiota from lean and obese mice to antibiotic-treated mice

    Ellekilde, M., Selfjord, E. M., Larsen, C. S., Jakesevic, M., Rune, Ida, Christensen, B. T., Vogensen, Finn Kvist, Nielsen, Dennis Sandris, Bahl, M. I., Licht, T. R., Hansen, Axel Kornerup & Hansen, Camilla Hartmann Friis, 2014, In: Scientific Reports. 4, 8 p., 5922.

    Research output: Contribution to journalJournal articlepeer-review

  339. Published

    Vitamin C

    Lykkesfeldt, Jens, Michels, A. J. & Frei, B., 2014, In: Advances in Nutrition. 5, 1, p. 16-18 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  340. 2013
  341. Published

    Ampicillin-improved glucose tolerance in diet-induced obese C57BL/6NTac mice is age dependent

    Rune, Ida, Hansen, Camilla Hartmann Friis, Ellekilde, M., Nielsen, Dennis Sandris, Skovgaard, K., Rolin, B. C., Lykkesfeldt, Jens, Josefsen, K., Christensen, B. T., Kihl, Pernille & Hansen, Axel Kornerup, 2013, In: Experimental Diabetes Research. 2013, 13 p., 319321.

    Research output: Contribution to journalJournal articlepeer-review

  342. Published

    Cardiac natriuretic peptide gene expression and plasma concentrations during the first 72 hours of life in piglets

    Smith, J., Christoffersen, Christina, Nørgaard, L. M., Olsen, Lisbeth Høier, Vejlstrup, N. G., Andersen, C. B. & Gøtze, J. P., 2013, In: Endocrinology. 154, 5, p. 1864-1872 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  343. Published

    Cardiac troponin-I concentration, myocardial arteriosclerosis, and fibrosis in dogs with congestive heart failure because of Myxomatous Mitral Valve Disease

    Falk, B. T., Ljungvall, I., Zois, N. E., Höglund, K., Olsen, Lisbeth Høier, Pedersen, H. D. & Häggström, J., 2013, In: Journal of Veterinary Internal Medicine. 27, 3, p. 500-506 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  344. Published

    Circadian Variation in the Response to Experimental Endotoxemia and Modulatory Effects of Exogenous Melatonin

    Alamili, M., Klein, M., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2013, In: Chronobiology International. 30, 9, p. 1174-1180 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  345. Published

    Comparative infectivity of three larval nematode species in three different salmonids

    Haarder, S., Kania, Per & Buchmann, Kurt, 2013, In: Parasitology Research. 112, 8, p. 2997-3004 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  346. Published

    Coronary flow and reactivity, but not arrhythmia vulnerability, are affected by cardioplegia during cardiopulmonary bypass in piglets

    Liuba, P., Johansson, S., Pesonen, E., Odermarsky, M., Hansen, Axel Kornerup, Forslid, A., Aburawi, E. H., Higgins, T., Birck, M. M. & Perez-de-Sa, V., 2013, In: Journal of Cardiothoracic Surgery. 8, 6 p., 157.

    Research output: Contribution to journalJournal articlepeer-review

  347. Published

    Decreased Right Ventricular Systolic Function in Dogs with Myxomatous Mitral Valve Disease

    Olsen, Lisbeth Høier, Reimann, Maria Josefine, Møller, J. E., Häggström, J., Jangdin, S. E., Falk, B. T., Uggla, T. & Zois, N. E., 2013, In: Journal of Veterinary Internal Medicine. 27, 3, p. 628-629 2 p., C6.

    Research output: Contribution to journalConference abstract in journal

  348. Published

    Does vitamin C deficiency increase lifestyle-associated vascular disease progression? evidence based on experimental and clinical studies

    Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Antioxidants & Redox Signaling. 19, 17, p. 2084-2104 21 p.

    Research output: Contribution to journalJournal articlepeer-review

  349. Published

    Endothelial cell death and intimal foam cell accumulation in the coronary artery of infected hypercholesterolemic minipigs

    Birck, M. M., Saraste, A., Hyttel, P., Odermarsky, M., Liuba, P., Saukko, P., Hansen, Axel Kornerup & Pesonen, E., 2013, In: Journal of Cardiovascular Translational Research. 6, 4, p. 579-587 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  350. Published

    Evaluation of the breeding program aiming at reducing the prevalence of myxomatous mitral valve disease in Cavalier King Charles Spaniels in Denmark

    Birkegaard , A. C., Reimann, Maria Josefine, Häggström, J., Martinussen, Torben, Pedersen , H. D. & Olsen, Lisbeth Høier, 2013, American College of Veterinary Internal Medicine, Congress Proceedings. Sellon, R. K. & McClure, J. T. (eds.). Lakewood, p. 172 1 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  351. Published

    Expression of immune relevant genes in rainbow trout following exposure to live Anisakis simplex larvae

    Haarder, S., Kania, Per, Bahlool, Q. Z. M. & Buchmann, Kurt, 2013, In: Experimental Parasitology. 135, 3, p. 564-569 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  352. Published

    Guinea pig ascorbate status predicts tetrahydrobiopterin plasma concentration and oxidation ratio in vivo

    Mortensen, A., Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrition Research. 33, 10, p. 859-867 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  353. Published

    Gut microbiota regulates NKG2D ligand expression on intestinal epithelial cells

    Hansen, Camilla Hartmann Friis, Holm, T. L., Krych, Lukasz, Andresen, Lars, Nielsen, Dennis Sandris, Rune, Ida, Hansen, Axel Kornerup & Skov, Søren, 2013, In: European Journal of Immunology. 43, 2, p. 447-457 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  354. Published

    Human and equine cardiovascular endocrinology: beware to compare

    Vekens, N. V. D., Hunter, I., Goetze, Jens P. , Decloedt, A., Clercq, D. D. & Loon, G. V., 2013, In: Cardiovascular Endocrinology. 2, 4, p. 67-76 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  355. Published

    Immune reactions in fish against parasites from protozoans to metazoans

    Buchmann, Kurt, Chettri, J. K., Desmukh, S., Jaafar, Rzgar, Haarder, S., Bahlool, Q. Z. M., Jørgensen, L. G. & Kania, Per, 2013, In: Fish and Shellfish Immunology. 34, 6, p. 1641 1 p.

    Research output: Contribution to journalConference abstract in journalpeer-review

  356. Published

    Increased systemic oxidatively generated DNA and RNA damage in schizophrenia

    Jørgensen, A., Brødbæk, K., Fink-Jensen, Anders, Knorr, U., Greisen Søndergaard, M., Henriksen, T., Weimann, A., Jepsen, P., Lykkesfeldt, Jens, Poulsen, Henrik Enghusen & Jørgensen, Martin Balslev, 2013, In: Psychiatry Research. 209, 3, p. 417–423 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  357. Published

    Increasing Contracaecum osculatum infections of Baltic cod (Gadus morhua L.) associated with grey seal (Halichoerus gryphus L.) colonization of spawning grounds.

    Haarder, S., Kania, Per, Galatius, A. & Buchmann, Kurt, 2013.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  358. Published

    Inflammation and bone remodeling in the delayed-type hypersensitivity (DTH) arthritis model

    Atkinson, S. M., Thorn, M., Autzen Usher, P., Fox, B., Serikawa, K., Biswas, S., Haase, C., Skov, Søren & Nansen, A., 2013, In: Scandinavian Journal of Immunology. 77, 4, p. 304

    Research output: Contribution to journalConference abstract in journal

  359. Published

    Influence of R-R interval variations on the degree of mitral regurgitation in dogs with myxomatous mitral valve disease

    Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2013, In: Journal of Veterinary Internal Medicine. 27, 3, p. 636-637 2 p., C-30.

    Research output: Contribution to journalConference abstract in journalpeer-review

  360. Published

    Kinetics of acid-induced degradation of tetra- and dihydrobiopterin in relation to their relevance as biomarkers of endothelial function

    Mortensen, A. & Lykkesfeldt, Jens, 2013, In: Biomarkers. 18, 1, p. 55-62 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  361. Published

    Laparoscopic Roux-en-Y gastric bypass in super obese Göttingen minipigs

    Birck, M. M., Vegge, A., Støckel, M., Gögenur, Ismail, Thymann, Thomas, Hammelev, Karsten Pharao, Sangild, Per Torp, Hansen, Axel Kornerup, Raun, K., von Voss, P. & Eriksen, Thomas, 2013, In: American Journal of Translational Research. 5, 6, p. 643-653 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  362. Published

    Left ventricular twist and circumferential strain in dogs with myxomatous mitral valve disease

    Zois, N. E., Olsen, N. T., Moesgaard, S. G., Rasmussen, C. E., Falk, B. T., Häggström, J., Pedersen, H. D., Møller, J. E. & Olsen, Lisbeth Høier, 2013, In: Journal of Veterinary Internal Medicine. 27, 4, p. 875-883 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  363. Published

    Nephrectomized and hepatectomized animal models as tools in preclinical pharmacokinetics

    Vestergaard, Bill, Agersø, H. & Lykkesfeldt, Jens, 2013, In: Basic & Clinical Pharmacology & Toxicology Online. 113, 2, p. 75-86 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  364. Published

    Occurrence of Diplostomum pseudospathaceum Niewiadomska, 1984 and D. mergi Dubois, 1932 (Digenea: Diplostomidae) in Danish freshwater snails: ecological and molecular data

    Haarder, S., Jørgensen, K., Kania, Per, Skovgaard, A. & Buchmann, Kurt, 2013, In: Folia Parasitologica. 60, 2, p. 177-180 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  365. Published

    Physiological parameters of endurance horses pre-compared to post-race, correlated with performance: a two race study from Scandinavia

    Larsson, J., Pilborg, P. H., Johansen, M., Christophersen, M. T., Holte, A., Roepstorff, L., Olsen, Lisbeth Høier & Harrison, Adrian Paul, 2013, In: ISRN Veterinary Science. 2013, 12 p., 684353.

    Research output: Contribution to journalJournal articlepeer-review

  366. Published

    Pigs in space

    Goetze, J. P., Hunter, I., Smith, J. & Hasenkam, J. M., 2013, In: Cardiovascular Endocrinology. 2, 1, p. 4-5 2 p.

    Research output: Contribution to journalJournal articlepeer-review

  367. Published

    Plasma proANP and SDMA and microRNAs are associated with chronic mitral regurgitation in a pig model

    Cirera, Susanna, Moesgaard, S. G., Zois, N. E., Ravn, N., Goetze, Jens P. , Cremer, Signe Emilie, Teerlink, T., Leifsson, Páll S., Honge, J. L., Hasenkam, J. M. & Olsen, Lisbeth Høier, 2013, In: Endocrine Connections. 2, 3, p. 161-171 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  368. Published

    ProANP plasma measurement predicts all-cause mortality in acutely hospitalised patients: a cohort study

    Lauridsen, B. K., Iversen, K., Hunter, I., Bay, M., Kirk, V., Nielsen, O. W., Nielsen, H., Boesgaard, S., Køber, Lars Valeur & Goetze, J. P., 2013, In: B M J Open. 3, 10 p., e003288.

    Research output: Contribution to journalJournal articlepeer-review

  369. Published

    Prolonged effect of a new O-glycoPEGylated FVIII (N8-GP) in a murine saphenous vein bleeding model

    Pastoft, A. E., Ezban, M., Tranholm, M., Lykkesfeldt, Jens & Lauritzen, B., 2013, In: Haemophilia Online. 19, 6, p. 913-919 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  370. Published

    Prolonged maternal vitamin C deficiency overrides preferential fetal ascorbate transport but does not influence perinatal survival in guinea pigs

    Schjoldager, J. G., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: British Journal of Nutrition. 110, 9, p. 1573-1579 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  371. Published

    R-R interval variations influence the degree of mitral regurgitation in dogs with myxomatous mitral valve disease

    Reimann, Maria Josefine, Møller, J. E., Häggström, J., Markussen, Bo, Holen, A. E. W., Falk, B. T. & Olsen, Lisbeth Høier, 2013.

    Research output: Contribution to conferencePosterResearch

  372. Published

    Regulation of vitamin C homeostasis during deficiency

    Lindblad, M. M., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2013, In: Nutrients. 5, 8, p. 2860-2879 20 p.

    Research output: Contribution to journalJournal articlepeer-review

  373. Published

    Translational aspects of rectal evoked potentials: a comparative study in rats and humans

    Nissen, T. D., Brock, C., Graversen, C., J. Coen, S., Hultin, L., Aziz, Q., Lykkesfeldt, Jens & Drewes, A. M., 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, p. G119-G128 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  374. Published

    Whey protein reduces early life weight gain in mice fed a high-fat diet

    Christensen, B. T., Hellgren, L., Lykkesfeldt, Jens, Sejrsen, K., Jeamet, A., Rune, Ida, Ellekilde, M., Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 2013, In: PLOS ONE. 8, 8, 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  375. Published

    Zebrafish as a model for inflammatory bowel disease (IBD)

    Haarder, S., Kania, Per, Hyttel, P., Lindebo Holm, T. & Buchmann, Kurt, 2013.

    Research output: Contribution to conferencePosterResearch

  376. 2012
  377. Published

    Evaluation of the piroxicam-accelerated interleukin-10 knock out mouse: - As a model of human inflammatory bowel disease.

    Holgersen, K., Kvist, P. H., Hansen, Axel Kornerup & Holm, T. L., Sep 2012.

    Research output: Contribution to conferencePosterResearchpeer-review

  378. Published

    Left ventricular twist and twist rate in dogs with mitral regurgitation attributable to myxomatous mitral valve disease

    Zois, N. E. & Olsen, Lisbeth Høier, Sep 2012. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  379. Published

    A sensitive venous bleeding model in haemophilia A mice: effects of two recombinant FVIII products (N8 and Advate®)

    Pastoft, A. E., Lykkesfeldt, Jens, Ezban, M., Tranholm, M., Whinna, H. C. & Lauritzen, B., 2012, In: Haemophilia. 18, 5, p. 782-788 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  380. Published

    Advanced electrocardiographic parameters change with severity of mitral regurgitation in Cavalier King Charles Spaniels in sinus rhythm

    Pakkanen, M. S., Petric, A. D., Olsen, Lisbeth Høier, Stepancic, A., Schlegel, T. T., Falk, B. T., Rasmussen, C. E. & Starc, V., 2012, In: Journal of Veterinary Internal Medicine. 26, 1, p. 93-100 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  381. Published

    Ascorbate and dehydroascorbic acid as biomarkers of oxidative stress: validity of clinical data depends on vacutainer system used

    Lykkesfeldt, Jens, 2012, In: Nutrition Research. 32, 1, p. 66-69 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  382. Published

    Ascorbate status modulates reticuloendothelial iron stores and response to deferasirox iron chelation in ascorbate-deficient rats

    Brewer, C., Otto-Duessel, M., Lykkesfeldt, Jens, Nick, H. & Wood, J. C., 2012, In: Experimental Hematology. 40, 10, p. 820-827 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  383. Published

    Chronic vitamin C deficiency does not accelerate oxidative stress in ageing brains of guinea pigs

    Tveden-Nyborg, Pernille, Andersen, S. H., Miyashita, N., Moos, T., Poulsen, Henrik Enghusen & Lykkesfeldt, Jens, 2012, In: Basic & Clinical Pharmacology & Toxicology Online. 110, 6, p. 524-529 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  384. Published

    Circulating cytokine concentrations in dogs with different degrees of myxomatous mitral valve disease

    Zois, N. E., Moesgaard, S. G., Kjelgaard-Hansen, M., Rasmussen, C. E., Falk, B. T., Fossing, C., Häggström, J., Pedersen, H. D. & Olsen, Lisbeth Høier, 2012, In: Veterinary Journal. 192, 1, p. 106-111 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  385. Published

    Discordant porcine cardiac natriuretic peptide gene expression and plasma concentrations during the first 72 h of life

    Smith, J., Christoffersen, C., Nørgaard, L. M., Olsen, Lisbeth Høier, Vejlstrup, N. G., Andersen, C. B. & Goetze, J. P., 2012, In: Regulatory Peptides. 177, Supplement, p. S33 1 p.

    Research output: Contribution to journalConference abstract in journalpeer-review

  386. Published

    Flow-mediated vasodilation measurements in Cavalier King Charles Spaniels with increasing severity of myxomatous mitral valve disease

    Moesgaard, S. G., Løwert, C. K., Zois, N. E., Teerlink, T., Molin, M., Falk, B. T., Rasmussen, C. E., Fuentes, V. L., Jones, I. D. & Olsen, Lisbeth Høier, 2012, In: Journal of Veterinary Internal Medicine. 26, 1, p. 61-68 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  387. Published

    Gut microbiota composition is correlated to grid floor induced stress and behavior in the BALB/c mouse

    Bendtsen, K. M. B., Krych, Lukasz, Sørensen, Dorte Bratbo, Pang, W., Nielsen, Dennis Sandris, Josefsen, K., Hansen, Lars Hestbjerg, Sørensen, Søren Johannes & Hansen, Axel Kornerup, 2012, In: P L o S One. 7, 10, 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  388. Published

    Heart rate, heart rate variability, and arrhythmias in dogs with myxomatous mitral valve disease

    Rasmussen, C. E., Falk, B. T., Zois, N. E., Moesgaard, S. G., Häggström, J., Pedersen, H. D., Åblad, B., Nilsen, H. Y. & Olsen, Lisbeth Høier, 2012, In: Journal of Veterinary Internal Medicine. 26, 1, p. 76-84 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  389. Published

    Immunological mechanisms of contact hypersensitivity in mice

    Christensen, A. D. & Haase, C., 2012, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 120, 1, p. 1-27 27 p.

    Research output: Contribution to journalReviewpeer-review

  390. Published

    Maternal vitamin C deficiency during pregnancy persistently impairs hippocampal neurogenesis in offspring of guinea pigs

    Tveden-Nyborg, Pernille, Vogt, L., Schjoldager, J. G., Jeannet, N., Andersen, S. H., Paidi, M. D., Christen, S. & Lykkesfeldt, Jens, 2012, In: P L o S One. 7, 10, 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  391. Published

    Oxidative stress response after laparoscopic versus conventional sigmoid resection: a randomized, double-blind clinical trial

    Madsen, M. T., Kücükakin, B., Lykkesfeldt, Jens, Rosenberg, J. & Gögenur, I., 2012, In: Surgical Laparoscopy, Endoscopy and Percutaneous Techniques. 22, 3, p. 215-219 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  392. Published

    Poor antioxidant status exacerbates oxidative stress and inflammatory response to Pseudomonas aeruginosa lung infection in Guinea Pigs

    Jensen, Peter Østrup, Lykkesfeldt, Jens, Bjarnsholt, Thomas, Hougen, H. P., Høiby, Niels & Ciofu, Oana, 2012, In: Basic & Clinical Pharmacology & Toxicology. 110, 4, p. 353-358 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  393. Published

    Radial and longitudinal strain and strain rate assessed by speckle-tracking echocardiography in dogs with myxomatous mitral valve disease

    Zois, N. E., Tidholm, A., Nägga, K. M., Moesgaard, S. G., Rasmussen, C. E., Falk, B. T., Häggström, J., Pedersen, H. D., Åblad, B., Nilsen, H. Y. & Olsen, Lisbeth Høier, 2012, In: Journal of Veterinary Internal Medicine. 26, 6, p. 1309-1319 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  394. Published

    Role of vitamin C and E supplementation on IL-6 in response to training

    Yfanti, C., Fischer, C. P., Nielsen, S., Åkerström, T., Nielsen, A. R., Veskoukis, A. S., Kouretas, D., Lykkesfeldt, Jens, Pilegaard, Henriette & Pedersen, Bente Klarlund, 2012, In: Journal of Applied Physiology. 112, 6, p. 990-1000 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  395. Published

    Vitamin C and its role in brain development and cognition

    Andersen, S. H., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2012, Nutrition and mental performance: a develomental perspective. Riby, L., Smith, M. & Foster, J. (eds.). Palgrave Macmillan, p. 29-52 24 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  396. Published

    What is the optimum intake of vitamin C in humans?

    Frei, B., Birlouez-Aragon, I. & Lykkesfeldt, Jens, 2012, In: Critical Reviews in Food Science and Nutrition. 52, 9, p. 815-829 15 p.

    Research output: Contribution to journalJournal articlepeer-review

  397. 2011
  398. Published

    Effect of inoculating C57BL/6NTac mice with different gut microbiotas on gut colonization and glucose tolerance

    Ellekilde, M., Viscardi, M., Rune, Ida, Vogensen, Finn Kvist, Nielsen, Dennis Sandris & Hansen, Axel Kornerup, 1 Nov 2011. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  399. Published

    The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice

    Rune, Ida, Hansen, Axel Kornerup, Ellekilde, M., Nielsen, Dennis Sandris & Hansen, C., Nov 2011. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  400. Published

    The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice

    Rune, Ida, Nielsen, Dennis Sandris, Hansen, Axel Kornerup, Ellekilde, M., Lykkesfeldt, Jens, Hansen, Camilla Hartmann Friis & Rolin, B., Nov 2011. 1 p.

    Research output: Contribution to conferencePosterResearch

  401. Published

    Animal models in pharmacology and toxicology

    Meyer, O. A., Svendsen, O. & Lykkesfeldt, Jens, 2011, Handbook of laboratory animal science: volume II: Animal models. Hau, J. & J. Schapiro, S. (eds.). 3. ed. ed. CRC Press, Vol. 2. p. 149-184 36 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  402. Published

    Development of rodents with a controlled gut microbiota and low variation

    Hansen, Axel Kornerup, Nielsen, Dennis Sandris, Vogensen, Finn Kvist, Hansen, Camilla Hartmann Friis, Ellekilde, M., Rune, Ida & Bech-Nielsen, G. V., 2011. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  403. Published

    Effect of antioxidant supplementation on insulin sensitivity in response to endurance exercise training

    Yfanti, C., Nielsen, A. R., Åkerström, T., Nielsen, S., Rose, A. J., Richter, Erik A., Lykkesfeldt, Jens, Fischer, C. P. & Pedersen, Bente Klarlund, 2011, In: American Journal of Physiology: Endocrinology and Metabolism. 300, 5, p. E761-E770 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  404. Published

    Effect of vitamin C and iron chelation on diesel exhaust particle and carbon black induced oxidative damage and cell adhesion molecule expression in human endothelial cells

    Frikke-Schmidt, H. R., Roursgaard, Martin, Lykkesfeldt, Jens, Loft, Steffen, Nøjgaard, J. K. & Møller, Peter, 2011, In: Toxicology Letters. 203, 3, p. 181-189 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  405. Published

    Fluctuating hyperglycaemia increases oxidative stress response in lean rats compared to sustained hyperglycaemia despite lower glycaemic exposure

    Rakipovski, G., Raun, K. & Lykkesfeldt, Jens, 2011, In: Diabetes and Vascular Disease Research. 8, 4, p. 295-298 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  406. Published

    High dietary fat and cholesterol exacerbates chronic vitamin C deficiency in guinea pigs

    Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille, Birck, M. M. & Lykkesfeldt, Jens, 2011, In: British Journal of Nutrition. 105, 1, p. 54-61 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  407. Published

    Reply to Hemilä by Lykkesfeldt and Poulsen

    Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2011, In: British Journal of Nutrition. 105, 3, p. 488 1 p.

    Research output: Contribution to journalLetterpeer-review

  408. Published

    Storage-induced increase in biomarkers of oxidative stress and inflammation in red blood cell components

    Kücükakin, B., Kocak, V., Lykkesfeldt, Jens, Nielsen, H. J., Magnussen, K., Rosenberg, Jacob & Gögenür, I., 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 4, p. 299-303 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  409. Published

    The effect of altered gut flora on glucose intolerance in C57BL/6NTac mice

    Rune, Ida, Ellekilde, M., Hansen, Camilla Hartmann Friis, Nielsen, Dennis Sandris, Rolin, B. C., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2011. 1 p.

    Research output: Contribution to conferencePosterResearch

  410. Published

    Vitamin C in human nutrition

    Frikke-Schmidt, H. R., Tveden-Nyborg, Pernille & Lykkesfeldt, Jens, 2011, Vitamins in the prevention of human diseases. Herrmann, W. & Obeid, R. (eds.). De Gruyter, p. 323-362 40 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  411. 2010
  412. Published

    Antioxidant supplementation does not alter endurance training adaptation

    Yfanti, C., Åkerström, T., Nielsen, S., Nielsen, A. R., Mounier, R., Mortensen, Ole Hartvig, Lykkesfeldt, Jens, Rose, A. J., Fischer, C. P. & Pedersen, Bente Klarlund, 1 Jul 2010, In: Medicine and Science in Sports and Exercise. 42, 7, p. 1388-95 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  413. Published

    Distribution and time course of corticosterone excretion in faeces and urine of female mice with varying systemic concentrations

    Kalliokoski, Otto, Hau, Jann, Jacobsen, K. R., Schumacher-Petersen, Camilla & Abelson, Klas, 2010, In: General and Comparative Endocrinology. 168, 3, p. 450-4 4 p.

    Research output: Contribution to journalJournal articlepeer-review

  414. Published

    Efficacy of Elimination of Pasteurella pneumotropica from a Mouse Specific Pathogen-Free Barrier Breeding Unit through Treatment with Enrofloxacin

    Østergaard, Grete, Arnorsdottir, S. E., Schumacher-Petersen, Camilla, Bundgaard, C. J., Koch, J. & Hau, Jann, 2010, In: JAALAS - Journal of the American Association for Laboratory Animal Science. 49, 5, p. 671-671 1 p.

    Research output: Contribution to journalConference abstract in journalpeer-review

  415. Published

    Is vitamin C supplementation beneficial? lessons learned from randomised controlled trials

    Lykkesfeldt, Jens & Poulsen, Henrik Enghusen, 2010, In: British Journal of Nutrition. 103, 9, p. 1251-1259 9 p.

    Research output: Contribution to journalJournal articlepeer-review

  416. Published

    Keeping the intracellular vitamin C at a physiologically relevant level in endothelial cell culture

    Frikke-Schmidt, H. R. & Lykkesfeldt, Jens, 2010, In: Analytical Biochemistry. 397, 1, p. 135-137 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  417. Published

    No effect of melatonin on oxidative stress after laparoscopic cholecystectomy: a randomized placebo-controlled trial

    Kücükakin, B., Klein, M., Lykkesfeldt, Jens, Reiter, R. J., Rosenberg, J. & Gögenür, I., 2010, In: Acta Anaesthesiologica Scandinavica. 54, 9, p. 1121-1127 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  418. Published

    No effect of melatonin to modify surgical-stress response after major vascular surgery: a randomised placebo-controlled trial

    Kücükakin, B., Wilhelmsen, M., Lykkesfeldt, Jens, Reiter, R. J., Rosenberg, J. & Gögenur, I., 2010, In: European Journal of Vascular and Endovascular Surgery. 40, 4, p. 461-467 7 p.

    Research output: Contribution to journalJournal articlepeer-review

  419. Published

    Obese Prone Rats on high- and low-fat diets gain weight equally

    Christensen, B. T., Hellgren, L., Sejrsen, K., Lykkesfeldt, Jens & Hansen, Axel Kornerup, 2010.

    Research output: Contribution to conferencePosterResearch